serotonin

GABA is a life saver for anxiety, theanine helps at night (insomnia) and 5-HTP makes a significant difference in lessening daily pain

September 16, 2022 By Trudy Scott 16 Comments

Joie has Sjogren’s, Hashimoto’s, fibromyalgia & collagenous colitis (all diagnosed after severe mold exposure) and shared how GABA is a life saver for her anxiety, how theanine helps at night with her insomnia and how 5-HTP makes a significant difference in lessening her daily pain. Here is her wonderful feedback in her own words (my feedback for her follows):

I was diagnosed with Sjogrens several years ago. I also have Hashimoto’s, Fibromyalgia & Collagenous Colitis. All of these happened after a severe mold exposure which destroyed my pituitary, and caused Exocrine Pancreatic Insufficiency (EPI). I have to take human growth hormone injections daily, as my pituitary isn’t working, digestive enzymes for the EPI, and have experienced the anxiety and depression you’ve written about.

The GABA has been a life saver for me (for my anxiety), and I share this with all I know who experience anxiety. I also use L-theanine at night because of insomnia. The 5-HTP has helped somewhat for sleep. L-tryptophan didn’t seem to make a difference. However the 5-HTP has made a significant difference in lessening my daily pain levels, which I am most grateful for.

Unfortunately, I am also taking Klonopin and Gabapentin, both of which I have tried to get off of but keep finding myself back on both in order to have greater than 5 hours of sleep at night. Even with these, I often awaken after 4-6 hours and take 1-2 chewable GABA which allows me to go back to sleep and get 2-4 more hours of sleep.

She shared this on the blog, Sjogren’s syndrome: tryptophan and GABA for anxiety, and moisturizing for dry skin and inflammation?, where I write about the prevalence of anxiety and depression in this autoimmune condition, and the fact that serotonin and GABA are often low.

I shared how sorry I was to hear how mold has impacted her but that it was wonderful to hear the GABA has been a lifesaver for you in terms of anxiety (and when waking in the night) and that theanine helps her sleep. It’s wonderful that 5-HTP helps ease her daily pain (here is fibromyalgia research on 5-HTP) and helps somewhat with her sleep issues.

Has she increased the amino acids to the optimal doses for her unique needs?

My question for her was this: “how much of each of these amino acids are you using and have you increased them to the optimal doses for your unique needs?” I asked this because many folks don’t do this and we always want to capitalize on what is working.

Here are some examples that relate to Joie:

When 5-HTP helps with pain relief we also do afternoon and bedtime trials to see if it can improve sleep further. And we always explore some of the reasons why serotonin may be low and address those too. You can read more on that here: what causes low serotonin

I shared that tryptophan doesn’t work for everyone and some do better with 5-HTP, but I do also consider melatonin when sleep is an issue, especially timed release to prevent waking in the night.

Since GABA is a lifesaver for her in terms of her anxiety and also helps when she wakes, trialing higher doses at bedtime may prevent the early morning waking. The same could be said for trialing a higher dose of theanine and using both GABA and theanine together at night (a 2019 study shows the combination decreases sleep latency and improves NREM sleep).

High cortisol, rebound sleep issues with meds and/or poor fat digestion?

If she has already done the above, I’d explore high cortisol and do a 5-collection an adrenal saliva test). When cortisol is high during the night, the use of Seriphos can be a game-changer for many.

Unfortunately both Klonopin and Gabapentin (especially the former) can cause rebound insomnia even when they seem to be helping in the short-term.

I also mentioned that my recent blog post many be helpful since she mentions exocrine pancreatic insufficiency, which could affect sleep by impacting her fat digestion – Waking in the night due to environmental toxins: impacts on the liver, gallbladder and fat digestion (making oxalate issues worse). This has relevance whether or not oxalates are an issue.

Autoimmune-Paleo (AIP) diet, pyroluria and moisturizing for reducing inflammation

It goes without saying that since Sjogren’s, Hashimoto’s and even Collagenous Colitis are autoimmune conditions, following an Autoimmune-Paleo (AIP) diet is key too. I have links to some AIP resources on the above Sjogren’s blog post.

In this blog I also mention pyroluria which may be relevant for someone with Collagenous Colitis and is crucial to address when there has been toxic mold exposure or other chronic issues like Lyme disease or MCAS. More on this here.

And you can also read about the value of moisturizing for reducing inflammation.

I thanked her and said I plan to share her results and my response as a new blog as I feel it will help others and give hope!

Resources if you are new to using amino acids as supplements

If you are new to using any of the amino acids as supplements, here is the Amino Acids Mood Questionnaire from The Antianxiety Food Solution (you can see all the symptoms of neurotransmitter imbalances, including low serotonin and low GABA).

If you suspect low levels of any of the neurotransmitters and do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the practitioner/health team you or your loved one is working with.

There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, gluten, blood sugar control, sugar cravings, self-medicating with alcohol and more.

The book doesn’t include product names (per the publisher’s request) so this blog, The Antianxiety Food Solution Amino Acid and Pyroluria Supplements, lists the amino acids that I use with my individual clients and those in my group programs. You can find them all in my online store.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA QuickStart Program (if you have low GABA symptoms). This is a paid online/virtual group program where you get my guidance and community support. Another option is the budget-friendly GABA QuickStart Homestudy Program.

If you need serotonin support, the Serotonin QuickStart Program is a good place to get help. This is also a paid online/virtual group program where you get my guidance on using tryptophan and 5-HTP safely, and community support during 5 LIVE Q&A calls. You can sign up to be notified when the next live launch of this program is happening.

If you are a practitioner, join us in The Balancing Neurotransmitters: the Fundamentals program. This is also a paid online/virtual program with an opportunity to interact with me and other practitioners who are also using the amino acids.

Wrapping up and your feedback

I’d love to hear if GABA helped with your anxiety and insomnia? What about theanine? And 5-HTP for your pain? Or melatonin for sleep?

Have you used taurine with success for fat digestion? Or Seriphos for high cortisol?

What else has helped you with symptoms like these ones?

If you have questions please share them here too.

Low lithium questionnaire and how we use lithium orotate with the amino acids

August 19, 2022 By Trudy Scott 44 Comments

This is the low lithium questionnaire that I use with new clients in order for us to figure out if a trial of low dose lithium, in the form of lithium orotate, may be helpful. The hallmark of low lithium is a rollercoaster of emotions. Keep in mind that this is just one of 12 questionnaires that I have my clients complete. Many of the following symptoms can have multiple causes, the labs may relate to other deficiencies and the conditions have other root causes. This questionnaire simply provides additional evidence that lithium orotate may help.

We typically do a lithium orotate trial, starting with 5 mg once a day, and going up to 10 mg twice a day. We do this after we have started trialing the respective amino acids for low serotonin, low GABA, low endorphins, low catecholamines and low blood sugar. A big clue that lithium orotate may be helpful (when many of the symptoms below are checked off) is when the amino acids for low serotonin (tryptophan or 5-HTP), low GABA (GABA or theanine), low endorphins (DPA or DLPA), low catecholamines (tyrosine or DLPA) and low blood sugar (glutamine) are not as effective as expected (based on the amino acids mood/neurotransmitter questionnaire).

Low lithium questionnaire

Symptoms
Mood swings (a rollercoaster of emotions)
Addictions and/or cravings
Depressed
Low self-esteem
Boredom
Easily distracted
Rebellious, disruptive behavior and/or aggressiveness
Irritability
Restless/internal anxiety (similar to low serotonin worry/ruminating anxiety)
Restless/external anxiety (similar to low GABA physical anxiety)
Anxiety ups and downs (fluctuations)
Melancholic pessimism
Suicidal thoughts
Disorganized with planning difficulties
Focus issues/ADHD
Insomnia
Procrastination and/or no initiative
Jack of all trades, master of none
Impulsive and/or lacking tact
Poor insight
Risky behavior
Cognitive issues
Migraines or cluster headaches

Effectiveness of amino acids
The amino acids for low serotonin, low GABA, low endorphins, low catecholamines and low blood sugar are not as effective as expected (based on the amino acids mood/neurotransmitter questionnaire)

Labs
Low white blood cell count
Low red blood cell count
Anemia
Low platelet count

Conditions
Anorexia nervosa
Heart disease (heart arrhythmias, history of heart attack)
Raised blood sugar or diabetes
Kleptomania
Alcoholism
Alzheimer’s disease
Fibromyalgia
Bipolar II
Gout
Hyperthyroidism
Nearsightedness or glaucoma
Herpes infections (current or prone to them)

If you are new to low dose lithium / lithium orotate

As I share in this blog, Upping my tryptophan and lithium orotate have been absolutely profound for me: I’ve been depression free and anxiety free for over a year, I’ve used lithium orotate with many clients and use it when folks have mood swings and anxiety ups and downs. It’s harder for the amino acids to work when there is a moving goal post and lithium orotate evens things out.

You can read Katrin’s wonderful results: “Upping my tryptophan dose and also including and upping the dose of lithium orotate has been absolutely profound for me. I’m off my SSRI/antidepressant (which I was off and on for a number of years). I’ve been depression/anxiety free for over a year. So fantastic.”

The above blog also includes additional information on the differences between low dose lithium / lithium orotate and prescription lithium carbonate. The latter is used at much higher doses and does have side-effects.

One of the many ways lithium works is via the impact on neurotransmitter production. This paper, Potential Mechanisms of Action of Lithium in Bipolar Disorder, states this: “At a neuronal level, lithium reduces excitatory (dopamine and glutamate) but increases inhibitory (GABA) neurotransmission.” It also increases protective proteins such as BDNF (brain-derived neurotrophic factor), helps reduce oxidative stress and is neuroprotective. This paper is referring to lithium carbonate and not lithium orotate but until we have more research on lithium orotate, I feel comfortable extrapolating, given what I’ve seen clinically with lithium orotate.

I’ve also blogged about low dose or microdose lithium here: Microdose lithium formulation is capable of halting signs of advanced Alzheimer’s and improving cognition. In a study published in 2020, “a team of researchers has shown that, when given in a formulation that facilitates passage to the brain, lithium in doses up to 400 times lower than what is currently being prescribed for mood disorders is capable of both halting signs of advanced Alzheimer’s pathology and of recovering lost cognitive abilities.” In this study, they used lithium citrate in similar doses as the lithium orotate i.e 3.2 mg to 6.4 mg NP03 based on 70kg of body weight (which is around 154.3 lbs).

Resources if you are new to using the amino acids as supplements (and where to get lithium orotate)

You can find the amino acid products I use and a number of different lithium orotate products in my online Fullscript store.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA QuickStart Program (if you have low GABA symptoms). This is a paid online/virtual group program where you get my guidance and community support. There are many moms in the program who are having much success with their kids.

Do you resonate with any of the above and have you used lithium orotate with success?

Was the rollercoaster of emotions and fluctuating anxiety a hallmark for you before using lithium orotate?

If you’re a practitioner, do you use lithium orotate with your clients or patients?

If you have questions please share them here too.

Upping my tryptophan and lithium orotate have been absolutely profound for me: I’ve been depression free and anxiety free for over a year

July 8, 2022 By Trudy Scott 67 Comments

Upping my tryptophan dose and also including and upping the dose of lithium orotate has been absolutely profound for me.

I’m off my SSRI/antidepressant (which I was off and on for a number of years). I’ve been depression/anxiety free for over a year. So fantastic.

Everyone is bioindividual, of course, so please avoid using my dosing regime, but it wasn’t until I increased the lithium orotate to 20mg a day – 10mg in the AM and PM.

Life changing

Katrin shared this wonderful feedback on Facebook and I’m sharing this today in order to illustrate how much tryptophan dosing can vary, when you may need to up your dosage of tryptophan, how the addition of lithium orotate may be the missing link, and increasing it may help further and to offer hope (as always). And I share my insights and some additional information on lithium orotate.

Katrin was inspired by a post of mine where I discussed increasing tryptophan over and above 500mg twice a day and only taking it when needed). She shared this:

I was taking 3g tryptophan split up between the hours of 2pm and bedtime. 3 grams was what I increased to after floundering on 500mg afternoon and evening. I don’t take it every day (as per your great suggestion of not taking an amino acid if you feel you don’t need to.) But if I’m having a stressful week etc and my serotonin tanks, I’ll start to take it again.

After the initial increase of lithium orotate, in conjunction with the tryptophan increase, that’s when I started to feel the real difference – the icing on the cake, so to speak (sugar-free, gluten free icing and cake, of course). Lithium orotate was the game changer.

She started with 5mg lithium orotate twice a day and then increased it to 10mg twice a day and has recently reduced this (more on this below).

Is there a role for lithium orotate in psychiatry?

If you’re new to lithium orotate, this editorial, Is there a role for lithium orotate in psychiatry?, is a useful introduction. Here are a few highlights:

The growing evidence from epidemiological studies mirror the cellular studies that suggest lithium is perhaps a crucial trace element necessary for optimum brain functioning. All these studies imply that adequate lithium intake may be neuroprotective. Conversely, inadequate lithium intake (especially in vulnerable individuals) may predispose and/or perpetuate a range of psychiatric and neurodegenerative conditions.
If further studies confirm this hypothesis, then a safe and effective lithium mineral supplement will be needed to correct this specific mineral deficiency. Advocates of lithium orotate argue that such a supplement already exists and that it is both safe and effective.
Lithium orotate has been used worldwide, mainly by non-medical health practitioners for over 30 years

Lithium orotate is used at low doses and the dosing is much lower and in a different form to prescription lithium (carbonate) that is prescribed for bipolar disorder. The above editorial explains some of the differences and standard daily dose:

To further illustrate the differences in the daily doses of elemental lithium between the orotate and carbonate forms, a single 120 mg tablet of lithium orotate contains about 5mg of elemental lithium. This is only 10% of the dose of elemental lithium that you would find in a single 250 mg tablet of lithium carbonate, which would have about 50 mg of elemental lithium.

There are no established (medical) guidelines for the daily dose of lithium orotate. However, the standard dose prescribed by alternative health practitioners is a single tablet of 120 mg of lithium orotate a day (which is equivalent to 5 mg of elemental lithium).

The authors conclude with this: “There have only been a few small trials done in humans, and they showed that lithium orotate was effective, safe and generally well tolerated.” Until we have more human trials we have to rely on what we see clinically. And based on what I’ve seen and the feedback from colleagues, there is most definitely a role for lithium orotate in psychiatry.

Lithium orotate works when there are mood swings and anxiety ups and downs

I’ve used lithium orotate with many clients and use it when folks have mood swings and anxiety ups and downs. It’s harder for the amino acids to work when there is a moving goal post and lithium orotate evens things out. Katrin said she resonates with this and this may be why the lithium orotate works so well for her.

There are not many studies on lithium orotate, although it’s exciting that there has been an increase in the last few years. This small study done in 1994, Effects of nutritional lithium supplementation on mood, mentions the “mood-improving and stabilizing effect.” They used a yeast based lithium supplement of 400 μg (which is just 0.4 mg) for former drug users of mostly heroin and crystal methamphetamine.

The above editorial states the following reported benefits of taking lithium orotate:

feeling calmer; experiencing fewer or less intense depressive, hypomanic or mixed affective symptoms; being less impulsive; experiencing less frequent and less intense suicidal thoughts or aggressive impulses; reduced consumption of alcohol and not getting as easily upset by stressors.

I also use a low lithium questionnaire with clients. A number of symptoms/signs other than mood swings provide a clue that you may have low lithium levels and lithium orotate may need to be trialed.

My insights on Katrin’s approach to increasing her tryptophan and adding/increasing lithium orotate

Katrin increased the tryptophan to 3g and added lithium orotate at the same time. I recommend changing one thing at a time i.e. do a trial or tryptophan, then increase the tryptophan for better results (increasing slowly from 500mg 2 x day to 1000mg 2 x day and then 1500mg 2 x day, and tracking symptom improvements); then add lithium orotate; and then increase lithium orotate for even better results. But if it’s done the way Katrin did it, you simply unwind things so you can figure out what is really working for you.

Keep in mind, the starting dose for tryptophan is 500mg twice a day and lithium orotate is 5mg once a day. I would never recommend that anyone starts on 3g tryptophan or 20mg lithium orotate.

Experimenting with different doses and combinations

Katrin stayed at this dosing and combination of tryptophan and lithium orotate for close to a year. When something is working well, you understandably don’t want to change things. But more recently she has been experimenting with different doses and combinations. She is what is is doing now:

“currently trying lithium orotate by itself, during the day while only taking 1g tryptophan at night before bed.”
“now I only take a lithium orotate dose of 5mg twice a day and I do that every second day. It’s working for me.”

This is the perfect way to adjust things and if she finds the new combination doesn’t work over the coming weeks and months she can adjust again.

Also, keep in mind that your needs change as your hormones fluctuate, when you’re under more stress, with seasonal changes (winter time/winter blues and due to seasonal allergies), if you’re exposed to a toxin such as lead (it can impact serotonin levels) or parasites etc.

It goes without saying that diet must be addressed too – gluten-free, sugar-free, caffeine-free, real whole food, quality animal protein, organic vegetables and fruit, fermented foods and healthy fats.

Resources if you are new to using the amino acids as supplements

You can find the Lidtke Tryptophan products I use and a number of different lithium orotate products in my online Fullscript store.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA QuickStart Program (if you have low GABA symptoms). This is a paid online/virtual group program where you get my guidance and community support. There are many moms in the program who are having much success with their kids.

Wrapping up and your feedback

With much appreciation for Katrin for sharing her wonderful success story – I’m so thrilled for her! I’d love to get this published as case studies to further add to the evidence. If you are a researcher or have a resource for me please do let me know.

Did you need to adjust your tryptophan dose for easing your anxiety, depression and other low serotonin symptoms? What adjustments did you make?

Have you found the addition of lithium orotate has helped keep things more even so the amino acids are more effective? What dosing works for you?

If you’re a practitioner, do you find the addition of lithium orotate to be helpful for your patients/clients?

If you have questions please share them here too.

How to alleviate the fear and anxiety associated with choking and vomiting in Avoidant Restrictive Food Intake Disorder (ARFID)

May 27, 2022 By Trudy Scott 14 Comments

According to The National Eating Disorders Association /NEDA, “Avoidant Restrictive Food Intake Disorder (ARFID) is a new diagnosis in the DSM-5, and was previously referred to as “Selective Eating Disorder.” ARFID is similar to anorexia in that both disorders involve limitations in the amount and/or types of food consumed, but unlike anorexia, ARFID does not involve any distress about body shape or size, or fears of fatness.”

As you can read on this page:

“Many children with ARFID also have a co-occurring anxiety disorder, and they are also at high risk for other psychiatric disorders”
There are also “fears of choking or vomiting” and
There is a “dramatic restriction in types or amount of food eaten” and they will often “only eat certain textures of food”

What we seldom see addressed is the biochemical causes of anxiety and fears which can show up as phobias and ongoing worrying and obsessing about ingesting certain foods. These are all typical low serotonin symptoms.

With low serotonin (you can see all the symptoms here) we use the amino acids tryptophan or 5-HTP to raise serotonin and alleviate these symptoms (often within a few minutes).

However, what do we do when a child (or adult) with ARFID has low serotonin and is too terrified to even consider a trial of tryptophan or 5-HTP? This may be because of fear of choking or vomiting and/or because of an aversion to the taste/texture and/or the fact that they are being offered something new that is not on their “safe foods” list.

There is a similar issue with low GABA which can show up as physical anxiety and tummy issues like “constipation, abdominal pain, upset stomach.” Intrusive thoughts are a common sign of low GABA too and this can manifest as a debilitating fear of choking and dying.

There is the same issue with not being able to have the individual use sublingual GABA as a supplement in order to alleviate these symptoms.

It’s for this reason, we have to be creative and find other ways to support serotonin and GABA.

Other ways to boost serotonin and GABA

The traditional ways that tryptophan/5-HTP and GABA are used is opened onto the tongue or swallowed or chewed. However, there are other ways to boost serotonin and GABA in these kids with ARFID, without further adding to their distress:

Experiment with using tryptophan or 5-HTP topically. I’m not aware of a commercial topical product but I recently mixed 500mg tryptophan powder (only tryptophan with no fillers) into a base cream (I used Primal Derma beef tallow) and used it topically with success.
Experiment in a similar way with using GABA topically. It could be made at home too (with a GABA only powder) or a product such as Somnium GABA cream is an excellent option (I have used this product with success). I suspect the liposomal GABA/theanine products may also work topically (but have yet to experiment with this option).
If tolerated, GABA powder swished in the mouth but not swallowed, may be an option once some of the anxiety and fears have been reduced. GABA powder doesn’t taste bad (it’s slightly sweet) and mixes well in water. By swishing some in the mouth it can help reduce the fear of choking and esophageal spasms (if they are present). It may also help with the sensation of a lump-in-the-throat (called globus pharyngeus) that some kids with ARFID describe.
Liquid zinc (zinc sulfate) tastes like water when zinc levels are low and may be tolerated. This 2021 paper, Macro- and Micronutrient Intake in Children with Avoidant/Restrictive Food Intake Disorder, lists low vitamin B1, vitamin B2, vitamin C, vitamin K, zinc, iron, and potassium in kids with ARFID. Zinc, iron and the B vitamins are all needed to make serotonin and GABA, and low zinc can reduce appetite. It’s also possible these children had low levels of some of these nutrients beforehand and that this contributed to their fears and restrictive eating.
Magnesium spray or other forms of topical magnesium creams can be used. Magnesium itself is calming and is a cofactor for making serotonin and GABA. An Epsom salts bath also provides magnesium and a warm bath with Epsom salts and an essential oil such as lavender is very calming.

Other less direct but equally effective approaches to include are:

gentle yoga (it supports GABA production and is calming)
swinging on an outdoor swing (reduces stress, cortisol and anxiety)
full spectrum light therapy (boosts serotonin)
vagus nerve support “This modern world can lead to overstimulation of the nervous system and you can become desensitized to chronic stress. Over time, this can lead to low vagal tone, which has been linked to a variety of mental and physical health issues.”
full spectrum infrared sauna (low heat and of short duration to simulate light exercise)
a weighted blanket is calming and improves mood and sleep and
essential oils such as orange (topically or diffused) can help with fear and anxiety.

Once serotonin and GABA levels have improved with some of the above measures, and more and more of the fear of choking and vomiting dissipates and food texture and taste aversion is reduced, the amino acids can then hopefully be introduced in the ways they are typically used (more on that below). This will further speed up the anxiety and fear reduction, allowing more and more foods to be slowly introduced.

If you are new to Avoidant Restrictive Food Intake Disorder (ARFID)

Be sure to read more about ARFID on The National Eating Disorders Association /NEDA site: diagnostic criteria, risk factors, warning signs and symptoms (behavioral and psychological, and physical).

As with all eating disorders, the risk factors for ARFID involve a range of biological, psychological, and sociocultural issues. These factors may interact differently in different people, which means two people with the same eating disorder can have very diverse perspectives, experiences, and symptoms.

Resources if you are new to using tryptophan/5-HTP and GABA as supplements

If you are new to using the amino acids as supplements, here is the Amino Acids Mood Questionnaire from The Antianxiety Food Solution (you can see all the low serotonin and low GABA symptoms).

If you suspect low levels of GABA or any of the neurotransmitters and do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the team you or your loved one is working with.

There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, blood sugar control, sugar cravings, self-medicating with alcohol and more.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA QuickStart Program. This is a paid online/virtual group program where you get my guidance and community support. There are many moms in the program who are having much success with their kids.

If you feel comfortable doing so, please share more about the ARFID struggles of your son or daughter in order to help more parents understand this disorder – their age, how long they have struggled, their fears and their safe food list.

Do let us know if you have found success with any of these approaches with your loved one with ARFID (or yourself)? And what other approaches have also helped?

If you are a practitioner are you seeing results with approaches like these with your ARFID clients/patients?

If you have questions please share them here too.

What causes low serotonin? Use tryptophan/5-HTP to help with the anxiety, overwhelm and worry right away and address all the root causes

May 13, 2022 By Trudy Scott 40 Comments

Low serotonin has a number of root causes which can be different for each person. If you do have low serotonin levels you always want to figure and address why it’s low. This can take time to figure out and resolve so you want to be using either tryptophan or 5-HTP (and sometimes both) to boost your serotonin levels and get symptom relief quickly. This helps with the worry, overwhelm, anxiety, insomnia, carb cravings, TMJ, irritability, PMS, anger, OCD, low mood and ruminations right away. It also helps with the worry and overwhelm triggered by sometimes complex and challenging root causes.

Here is a list of some of the many factors that may cause low serotonin for you:

stress and adrenal dysfunction (high cortisol affects your sex hormone and neurotransmitter production, inlcuding serotonin)
eating junk food and sugar (a Western diet “of processed or fried foods, refined grains, sugary products, and beer was associated with a higher odds of mood disorders”
consuming caffeine (which reduces zinc and B vitamins, needed to make serotonin)
not consuming enough quality animal protein (amino acids are the building blocks of our neurotransmitters, and grass fed red meat provides zinc, iron and omega-3s – all needed to make serotonin)
low stomach acid (meaning you can’t digest the protein you’re consuming)
gluten issues (leading to low serotonin and other nutritional deficiencies such as low iron, low vitamin D etc.)
low vitamin D (“Brain serotonin is synthesized from tryptophan by tryptophan hydroxylase 2, which is activated by vitamin D hormone”)
low iron/ferritin levels (iron is a cofactor for making serotonin)
dysbiosis and microbiome imbalances (we make so much serotonin in the gut)
candida (in one study short exposure to serotonin resulted in antifungal activity)
liver issues (affecting how you process xenoestrogens)
low bile production (affecting how you digest the healthy fats you’re eating)
sex hormone imbalances (serotonin and estrogen are very closely linked and women make less serotonin than men. In one study, tryptophan improved the low serotonin PMS symptoms)
thyroid imbalance (“it is postulated that one mechanism, among others, through which exogenous thyroid hormones may exert their modulatory effects in affective illness is via an increase in serotonergic neurotransmission”)
histamine imbalances (in one study “Acute LPS-induced inflammation increases CNS histamine and decreases CNS serotonin)”
the birth control pill (which lowers zinc and vitamin B6, both of which are needed for serotonin production)
statins (leading to cholesterol that is too low)
mold exposure/mycotoxins/mold poisoning
heavy metal toxicity such as lead (and tryptophan and ascorbic acid can help ease the anxiety)
Lyme disease and other co-infections (serotonin was found to be low in cerebrospinal fluid in patients with post-Lyme disease syndrome i.e. chronic Lyme)
collagen consumption (in susceptible folks this can lower serotonin levels)
seasonal allergies (“Cytokines may lead to a mood disturbance via the expression of the IDO enzyme, which shifts the synthesis of tryptophan from serotonin to kynurenine. The resultant acute tryptophan depletion results in decreased brain serotonin”)
genetics (one example is the MTHFR polymorphism)
low zinc, low vitamin B6 (and other B vitamins), low selenium, low magnesium etc. – all needed to make serotonin
oxalates (which can bind to zinc and deplete it)
a high copper diet (nut flours on Paleo diets can be problematic), copper IUD, copper pipes etc. (which can cause low zinc)
lack of nature (forest bathing reduces cortisol which affects serotonin production)
lack of exercise
lack of sunshine (like in the winter when serotonin declines)

When I posted some of this list on Facebook earlier this week, there was a great deal of interest, hence this blog. I’ve included one relevant link for each one so you can read further on the topic.

When I posted it I also asked this: “Have you figured out your root cause/s that are contributing to your low serotonin levels? And has tryptophan or 5-HTP helped while you’re figuring it all out?”

Leanne has mold, dysbiosis, Lyme, low vitamin D, bile issues and more

Leanne responded and gave me the go ahead to share especially if this helps someone else (I appreciate that!) She shared she has identified these root causes:

Mold. Dysbiosis. Possible Lyme/co-infections. Low vitamin D. Bile and motility issues. Liver issues. Stress. Low HCL. Those are the ones I’m aware of. And taking each and every day to work on them. It takes time to heal

I agree it takes time to heal and can be a longer journey for some folks, especially when there are a number of underlying factors. She is in a good frame of mind, saying pragmatically, it takes time to heal. This confirms her serotonin levels are robust i.e. she is not in a state of overwhelm and worry. Sure enough, when I asked if tryptophan or 5-HTP has been helping this was her response:

5-HTP and GABA calm initially helped me in my first round of going through this back in 2015. Then I discovered l-tryptophan about a year ago and that seemed to be a better help over 5-HTP.

Since I’ve just identified that histamine is an issue and started a low histamine diet this past week I noticed less of a need for l-tryptophan as I did before. My body is calming down significantly. And my digestion is working a little better.

But I still have to address mold, SIBO, candida, parasites and possibly Lyme and underlying hidden viruses.

So I know these amino acids will play a key part in supporting me as I dive deeper into addressing them all.

It’s wonderful the amino acids have helped her so much and they will most likely continue to help. A quick comment on her preference for tryptophan over 5-HTP – some folks do better on one vs the other.

Regarding the histamine issues/root cause, it’s good that she is now addressing this. Already she needs less tryptophan (for now). Things may fluctuate in the future again as she peels away the onion layers of root causes. She may find she needs tryptophan again or a higher dose or needs to get back on the GABA.

As you can see she has been working on her health for some time. This is not unusual. Slow and steady is just fine, especially when there is so much going on.

The amino acids are intended for short-term use while diet and underlying root causes are addressed. But when the list is long this is a common reason for the ongoing need for serotonin support. Keep in mind, your list may be a short one and may be quick to resolve. And not everyone has the same root causes.

Resources if you are new to using tryptophan or 5-HTP as supplements

If you are new to using tryptophan or 5-HTP as supplements, here is the Amino Acids Mood Questionnaire from The Antianxiety Food Solution (you can see all the low serotonin symptoms).

If you suspect low levels of serotonin or any of the neurotransmitters and do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the team you or your loved one is working with.

There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, blood sugar control, sugar cravings, self-medicating with alcohol and more.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), if you need serotonin support, the Serotonin QuickStart Program is a good place to start. This is a paid online/virtual group program where you get my guidance on using tryptophan and 5-HTP safely, and community support during 5 LIVE Q&A calls. You can sign up to be notified when the next live launch of this program is happening. We take a deep dive into product options including Lidtke products and others if you’re not able to access Lidtke.

Low GABA can cause physical tension and overwhelm, affect sleep and cause stress eating. If you also have low GABA symptoms, the next step to get help is the GABA QuickStart Program. This is also a paid online/virtual group program where you get my guidance and community support. Another option is the budget-friendly GABA QuickStart Homestudy Program.

Have you figured out your root cause/s that are contributing to your low serotonin levels? And does this give you a better understanding of your own issues?

Wrapping up

Now I’d love to hear from you ….

Do you have any other root causes I may have missed? (when I posted this list on Facebook, a few people pointed out I had missed a few. I’ll update the list and continue to add as we discover new connections).

Has tryptophan and/or 5-HTP helped you feel less overwhelmed and worried while you’re figuring it all out?

Have you adjusted doses of tryptophan and/or 5-HTP as things change and root causes are addressed/resolved?

If you’re a practitioner, do you have anything to add and do your clients/patients find this useful?

If you have questions please share them here too.

Thera360 Plus: my portable full-spectrum infrared sauna from Therasage (better sleep and digestion, more energy, and even more joy!)

April 29, 2022 By Trudy Scott 39 Comments

Today I’m sharing why I personally chose the Thera360 Plus, a portable full-spectrum infrared sauna from Therasage. And I also share my feedback on how I feel after using this sauna. I also have a call to action asking you to share your sauna experiences so the community can benefit from the collective wisdom of everyone who has one or uses one.

I also highlight some of the many health benefits of regular sauna sessions – both mental and physiological.

Mental health benefits: improved well-being, reduced pain, stress reduction and improved sleep

Here are some of the mental health benefits from this paper, Clinical Effects of Regular Dry Sauna Bathing: A Systematic Review):

In addition to having profound physiological effects, sauna bathing is reported to have beneficial psychological effects that are reflected in the many reports of improved well-being and pain tolerance.
The psychological impact of sauna bathing may be due to a combination of factors that include release of endorphins and other opioid-like peptides such as dynorphins, forced mindfulness, psychological stress reduction, relaxation, improved sleep, time out from busy life schedules, placebo effects, and other aspects of individual psychological and social interactions that likely occur around frequent sauna activity.
While it is difficult to distinguish between the different factors that produce positive psychological effects, such effects may enhance other physiological and metabolic benefits as they are likely to promote adherence to regular sauna activity.

Remember, endorphin release leads to feeling joyful.

And this last bullet is an important one to highlight: when you really enjoy doing something you are more likely to continue doing it. This means you’ll continue to see benefits.

There is also research that supports serotonin-boosting effects and cortisol-lowering effects, both of which are important when it comes to anxiety and mood too. (I’ll address this in a future blog on saunas, together with other mechanisms).

Physiological benefits: reduced inflammation, benefits for Alzheimer’s, reducing toxins and improved heart health

Here are a few studies you can read to learn more about some of the many physiological benefits of sauna:

Elevating body temperature to reduce low-grade inflammation: a welcome strategy for those unable to exercise?
Could Heat Therapy Be an Effective Treatment for Alzheimer’s and Parkinson’s Diseases? A Narrative Review
Evaluation of Interventions to Reduce Firefighter Exposures
Sauna bathing is associated with reduced cardiovascular mortality and improves risk prediction in men and women: a prospective cohort study
Effectiveness of a far-infrared low-temperature sauna program on geriatric syndrome and frailty in community-dwelling older people [improvements were noted]
Effects of Waon therapy on chronic fatigue syndrome: a pilot study [Waon therapy is a type of far infrared sauna and improvements were noted]
Sauna as a valuable clinical tool for cardiovascular, autoimmune, toxicant- induced and other chronic health problems [they are safe and offer multiple health benefits to regular users].

And this is an excerpt from the Therasage site

The Thera360 Plus sauna enhances mitochondrial health and cellular energy, improves microcirculation and blood oxygenation, enhances the natural production of nitric oxide, offers skin and anti-aging benefits, and the best natural detoxification possible, along with all the amazing health benefits of Full Spectrum Infrared.

The many positive features that helped me pick this sauna

The Thera360 Plus is the sauna I own and endorse. Here are a few of the many positive features that helped me decide to purchase this one (I did a fair amount of research and did look at other units too):

It is a full-spectrum (near and far) infrared sauna
It comes with red light/photobiomodulation panels (which also help with pain, mood and reducing inflammation).
It has the tourmaline gemstones built-in (these generate negative ions so it feels like you’ve been at the beach or a waterfall).
The chair and foot base is made of non-toxic bamboo materials. I’m used to having to leave new items outside for days in order to off-gas. I was surprised that this was not needed. Their “No Off-Gassing” message holds true.
The bamboo foot base is a grounding mat.
It is low EMF and shields not only EMF’s but also ELF’s, RF’s and dirty electricity. Before I purchased my sauna, I met with the owner and am super-impressed by this feature. It’s a really important factor for me and anyone with anxiety or chronic illness and/or electromagnetic hypersensitivity). As soon as it arrived I set it up (set up is so easy) and got out my meter and measured all the EMFs and sure enough there is no exposure when inside the sauna.
The digital temperature controller is simple to use.
It’s portable, small and convenient to use.
It’s affordable, is made in California and the company ships internationally.

My personal feedback as to how I feel after using this sauna

For me, this infrared sauna (with red light therapy and tourmaline) helps me with sleep, digestion and energy primarily (I have chronic Lyme). I also know it’s helping me with ongoing detoxification, mitochondrial health, stress reduction and mood support, immune function and cardiovascular health.

The good news is that the sauna has anti-inflammatory benefits and provides me with wonderful relief from pain, muscle spasms and other injuries.

Also, I feel a real sense of joy after using it … I can’t stop smiling for hours after a session. That is the endorphin and serotonin boost I’m getting, plus some of the benefits of negative ions! I love the outdoors and after a session in the sauna, I almost feel like I’ve been for a hike or walk on the beach.

I’ve also positioned my sauna facing a large window that looks onto our covered patio. It has lots of greenery and I can see the blue sky off to the left. This is particularly pleasant on a cold winter’s day and I get some of the benefits of nature.

I love the bamboo chair that ships with it but it wasn’t providing me with any lower back support (I’m prone to back injuries). I made a modification with a bamboo garden stake and PVC bracket (with some help from my darling father-in-law). Here are some images in case it’s something you’ve been considering….it works perfectly for the back support I need, keeps my bare back exposed to the heat and the bamboo garden stake slides out if needed.

A more in-depth blog post: mechanisms and additional insights

I believe we can all benefit from regular sauna bathing! And I’ll be sharing a more in-depth blog post on additional benefits of infrared sauna, some of the mechanisms, how to interpret the research (since there is so much research on traditional/Finnish saunas which are shorter duration and higher temperatures), how to assess the different saunas that are available, and how to use one and get the most benefits.

I’ll also share my insights on using sauna bathing for benzodiazepine, SSRI, opioid and alcohol detox; why folks with pyroluria may see specific benefits; and using sauna bathing to help reduce the impact of these things that increase anxiety – toxic mold, heavy metals, Lyme disease, pesticides, glyphosate, fluoride, phthalates and much more.

Learn more about the Thera360 Plus sauna here on the Therasage site. If you decide to purchase use coupon code TRUDY10 to save 10%.

I was confused when I started looking into saunas and if you’ve been following me for a while you know I like to share what I learn – hence this blog post. I’m still learning and will continue to share in follow-up posts.

There are many excellent saunas available for purchase and this is just one of them that I landed upon after researching a number of them.

If you have a home sauna, please share:

which one you have
why you purchased this type/brand (or use this type of sauna)
and the benefits you have experienced.

And do feel free to share more about:

how you use yours – duration, frequency, temperature
what you do before and after (for hydration)
if you dry-brush (before or after)
if you use certain nutrients (like niacin, charcoal, magnesium and other electrolytes, glutathione, NAC etc)
anything else you do as part of your sauna bathing
what other detox approaches you use (such as rebounding or castor oil packs etc).

By using the collective wisdom from this community we can all learn and benefit. And giving/contributing gives you a nice endorphin boost too!

If you have questions please share them here too.