anxiety

Help! I’m worried all the time! Soothe with supplements and tame worry with food!

April 20, 2018 By Trudy Scott Leave a Comment

Some of my simple tips for worry were shared in the April edition of Women’s World so here they are for you to enjoy in case you didn’t see them in the magazine. I’m quite chuffed to see it’s for a piece called “Ask America’s Ultimate Experts.”

I share tips about the benefits of a B- complex vitamin (for adrenal support), vitamin B6 (especially for PMS-type anxiety and worry, the calming amino acid called GABA, plus the mood-boosting and calming benefits of a grass-fed burger (loaded with zinc, iron and omega-3s) and pumpkin seeds as a snack (because they’re rich in both tryptophan and zinc)

Here are my tips from the article:

#1 Soothe with supplements

Here are some supporting articles and research for some of the above tips. A good B- complex vitamin for adrenal support has been shown to minimize psychological stress after a natural disaster and vitamin B6 (or pyridoxine) helps with PMS-type anxiety and worry.

A paper titled Pyridoxine in the treatment of premenstrual syndrome: a retrospective survey in 630 patients, reports the following results:

The daily doses of pyridoxine hydrochloride varied from 40 to 100 mg early in the study and from 120 to 200 mg in the later period of the investigations. The response to treatment was recorded as good (no significant residual complaints) in 40 per cent or more of patients taking 100-150 mg pyridoxine daily and in 60 per cent of patients treated with 160-200 mg daily. Together with partial response (useful benefit but still some significant complaints), the positive effect of the treatment increased to 65-68 per cent and 70-88 per cent respectively. No symptoms consistent with a diagnosis of peripheral neuropathy were reported

The calming amino acid called GABA helps with the physical-tension and stiff-and-tense-muscles type of anxiety and helps with worry and inhibition of unwanted thoughts.

#2 Tame worry with foods

Professor Felice Jacka, nutritional psychiatry researcher, discusses the mood-boosting and calming benefits of grass-fed beef (loaded with zinc, iron and omega-3s) on our Anxiety Summit interview: The Research – Food to prevent and treat anxiety and depression?

Pumpkin seeds are rich in tryptophan and zinc and research shows that a functional food made from these seeds actually helps with social anxiety.

Here are a few minor discrepancies in the above sections:

In #1 dopamine is not a calming brain chemical but instead it’s stimulating and helps with focus and motivation. The B vitamin mentioned contain folic acid whereas methyl folate is the preferred choice.
In #2 the GABA product recommended is 500mg and I find starting much lower is a more effective approach with my clients.

#3 Cue calm – open a worry window

Opening a worry window is a new approach for me and I’d love to hear if it helps you now or has helped you in the past.

Anti-anxiety gummies and low serotonin

Ali Miller, RD, shares a recipe for anti-anxiety gummies (you can see it in the PDF) and I love that it includes coconut water, ginger and turmeric. I’d replace the cup of orange juice (which is high in sugar) with water and use 2 tablespoons instead. Be sure to watch that these gelatin gummies don’t make your anxiety (or depression or sleep worse). It’s a small amount of gelatin but if you’re eating a lot of them and you’re prone to low serotonin, this may be a problem for you. I write about this in a blog post here – Collagen and gelatin lower serotonin: does this increase your anxiety and depression? If it does cause an adverse reaction it doesn’t mean you can’t eat them, instead it simply means you may need to take tryptophan when eating them (if low serotonin is the issue.

If you’d like a PDF of the article you can grab a copy here.

I’d love to hear if any of these approaches have helped you or your clients/patients. Keep in mind that it’s a fun article that is by no means comprehensive in terms of addressing all the possible root causes of anxiety.

Could yeast infections impair recovery from mental illness?

April 13, 2018 By Trudy Scott Leave a Comment

Julia Rucklidge, PhD, is an associate professor in the Department of Psychology, University of Canterbury, Christchurch, New Zealand and has published a number of studies looking at “micronutrients to treat psychiatric disorders including attention-deficit/hyperactivity disorder (ADHD), mood disorders, stress, and anxiety,” where benefits were reported. “Despite the positive benefits associated with micronutrients, some factors may limit a positive response, one of which may be the overgrowth of intestinal Candida.”

In this 2013 paper, Could yeast infections impair recovery from mental illness? A case study using micronutrients and olive leaf extract for the treatment of ADHD and depression the authors discuss the impact of candida on gut health and response to supplementation:

a number of factors influence optimal response and absorption of nutrients, including the health of the gut, particularly the presence of yeast infections, such as Candida.

As part of a wider investigation into the impact of micronutrients on psychiatric symptoms, many participants who experienced a yeast infection during their treatment showed a diminished response to the micronutrients.

One particular female client was followed for a 3-year period:

Kate (an alias) is a 24-year-old female of European descent who had participated in the 2010 trial by Rucklidge et al using micronutrients for the treatment of ADHD. In the past, she had been prescribed methylphenidate [Ritalin] by a psychiatrist but could not tolerate the side effects.

For just over 2 years, while using the micronutrient, she had no ADHD or mood symptoms, other than a mild increase around her period.

About 2.5 years participating in the trial, Kate started to feel increasingly unwell and reported the following:

(1) a chronic sore throat; (2) a constant runny nose; (3) cramps; (4) itchy toes, anus, and vagina; (5) rashes on her legs and groin area; and (6) an overall flu-like feeling. Concomitantly, all her psychiatric symptoms had returned… She was moody, anhedonic (unable to experience pleasure), and chronically irritable and was having cravings for sugary and starchy foods. Kate visited her family physician, who diagnosed Kate with a vaginal yeast infection

Over the next year, it was found that her psychiatric symptoms (ADHD and mood) got worse when she was infected with Candida and then her ADHD and mood symptoms improved once she was successfully treated with olive leaf extract and probiotics.

The study makes this conclusion about the role of inflammation, gut health and nutrient absorption:

This case outlines that micronutrient treatment might be severely compromised by infections such as Candida and may highlight the importance of gut health when treating psychiatric disorders with nutrients.

Given the role that inflammation can play in absorption of nutrients, it was hypothesized that the infection was impairing absorption of the micronutrients.

The authors also mention the growing body of literature on the gut-brain connection and how

the gut microbiota can influence brain function and subsequent psychiatric functioning.

Candida is always considered as one of many possible root causes with my anxious clients – it can contribute to anxiety as well as ADHD and depression, and out-of-control-sugar and intense carb cravings.

Olive leaf extract is one of many approaches for eliminating candida is more commonly used in Australia and New Zealand.

Another approach is to use garlic and oregano to kill the candida. I have great success with these products from Designs for Health:

Allicillin – a garlic product that contains Garlicillin®, a blend of garlic oil and parsley oil with specified levels of garlic sulfides and ajoene, the most bioactive compound formed from garlic and
Oil of Oregano – which has powerful antioxidant and intestinal cleansing benefits. It also helps to maintain a healthy microbial balance. This product is standardized for carvacrol and thymol, the principal phenolic compounds in oregano

Probiotics are also part of the protocol, as are dietary changes. Fresh garlic, onion, daikon, olive oil, coconut oil, lemon, apple cider vinegar, fermented vegetables and coconut oil are all therapeutic foods on an anti-candida diet.

In addition to killing the candida and restoring the good bacteria with probiotics, I also use targeted individual amino acids to help reduce the sugar and carb cravings, making it easier to quit the bread, sugar, cookies, cakes and fruit. These amino acids can also help to alleviate some of the anxiety, mood and ADHD symptoms from day one, offering relief and hope right away since eliminating candida is not a quick process:

tryptophan for afternoon cravings and mental worry (tryptophan also has some direct anti-candida effects – more to come on this in the future blog)
GABA for stress-related cravings and physical anxiety
glutamine for intense sugar cravings and low blood sugar
DPA for reward eating and weepiness
tyrosine for cravings due to low energy and low motivation

[all of the above supplements, including Allicillin, Oil of Oregano, various probiotics and an olive leaf product, called Olivirex Combination, can be ordered via my online store – details for creating an account on my supplements page. The category once you login is candida/dysbiosis]

Have you experienced anxiety, depression, panic attacks, ADHD and cravings with candida?

Have supplements that worked in the past stop working while you’re dealing with the candida?

Have you found the amino acids to help with anxiety and cravings while you’re addressing your candida?

Ketogenic diet: reductions in auditory hallucinations and delusions, better mood and energy, and weight loss

April 6, 2018 By Trudy Scott 2 Comments

Two schizoaffective patients of Dr. Chris Palmer, a psychiatrist from Harvard’s McLean Hospital in Belmont, Massachusetts, tried a ketogenic diet for weight loss. As well as losing weight, they experienced reductions in auditory hallucinations and delusions, had a better mood and had more energy.

Here is additional information about these remarkable results, published late last year in this letter to the editor – Ketogenic diet in the treatment of schizoaffective disorder: Two case studies.

The male patient: lost weight, reductions in auditory hallucinations and delusions, better mood and energy

The male patient, diagnosed with schizoaffective disorder, with a prior psychiatric history of attention deficit hyperactivity disorder and major depression, experienced “dramatic” reductions in auditory hallucinations and delusions, as well as better mood and energy on the ketogenic diet. He also lost weight, losing 104 pounds over the course of a year.

He weighed 322 lb and wanted to lose weight by following a ketogenic diet, typically consisting of coffee with medium chain triglyceride (MCT) oil and butter (“bulletproof coffee”), eggs, meat, fish, poultry, spinach, kale, and olive oil. Within 3 weeks, he had lost 15 lb, but also noted a dramatic reduction in his auditory hallucinations and delusions, and improvement in his mood, energy, and ability to concentrate. For the past year, he has largely remained on this ketogenic diet and has lost 104 lb.

His functioning has improved and he has become more independent:

He completed a certification course, successfully participates in an online college program, has friends, began dating, and moved from his father’s home into an independent apartment.

The female patient: lost weight, resolution of her delusions

After four weeks on the ketogenic diet, the female patient, also diagnosed with schizoaffective disorder, and with a prior psychiatric history of major depression and anorexia nervosa, had resolution of her delusions and lost ten pounds:

she wanted to lose weight, and went on a ketogenic diet, consisting mostly of coffee, eggs, poultry, and lettuce. Within 4 weeks, she lost 10 lb and noted that her delusions were no longer present, and that her mood and energy were much better. After 4 months, she lost a total of 30 lb and her PANSS score decreased to 70 [down from 107]

In both instances their symptoms returned when they stopped the diet, but then improved again when back on the ketogenic diet.

In case you’re not familiar with the ketogenic diet here is a quick summary:

The ketogenic diet is a high-fat / low carbohydrate [and low protein] diet that has been used since the 1920’s to treat childhood epilepsy, with some studies suggesting that over 50% of patients experience significant reductions in seizure frequency. The ketogenic diet results in ketone bodies, instead of glucose, being used as the primary energy source in the brain.

There simply is no psychiatric medication available with the power to accomplish these results

I had the pleasure of meeting Dr. Georgia Ede, MD last year at the ISNPR conference. She is a Harvard-trained psychiatrist and nutrition consultant practicing at Smith College, and writes about these two schizoaffective cases in her article – Low-Carbohydrate Diet Superior to Antipsychotic Medications:

These outcomes are truly remarkable: improvement by dozens of points on the PANSS, significant weight loss, and better quality of life. There simply is no psychiatric medication available with the power to accomplish these results.

I agree with Dr. Ede especially when we look at the medications these patients had trialed. These medication trials for the male patient: methylphenidate, amphetamine salts, dextroamphetamine, bupropion, sertraline, paroxetine, buspirone, lamotrigine, lorazepam, clonazepam, gabapentin, haloperidol, perphenazine, aripiprazole, olanzapine, quetiapine, and clozapine. The female patient had a similarly long list of medication trials and she also received 23 electroconvulsive therapy treatments. For both of them, positive and negative symptoms persisted.

I do still have questions about the ketogenic diet

The research in epilepsy is extensive and the research in mental health is growing. I am really impressed with the results, but I do still have questions about the ketogenic diet. Perhaps you have some similar questions and concerns. Here goes…

If this particular nutritional psychiatry approach works so well for severe mental health disorders such as schizophrenia and psychosis, how will it work for less severe conditions like anxiety and panic attacks? Are these severe cases like the “canaries in the coal-mine” paving the way and teaching us about the benefits of this way of eating?
Should you use a ketogenic dietary approach as the first approach or consider it as a last resort once the other dietary approaches have been implemented and you’re not seeing full symptom resolution? In other words, should you start with a real whole foods diet, then implement a gluten-free diet, then a grain-free diet, then remove dairy (if it’s an issue), then incorporate low FODMAPs if needed and only then implement a ketogenic diet? (low oxalate, low salicylate and low histamine would be incorporated as needed earlier in the process, based on each person’s unique needs). If we look only at schizoaffective disorder, there is growing evidence of the role of gluten in some individuals with this paper “suggesting that an antigliadin IgG positive population of schizophrenia could be a distinct subgroup.” This 2 person pilot study reports the benefits of a gluten-free diet: “this potential mechanism is exciting and may provide improvement for up to one-fourth of patients (antibody-positive) who suffer from this devastating disorder.”
How do we clearly define a ketogenic diet and communicate this definition to practitioners and to those who choose to implement this way of eating on their own? I’ve had feedback from many people who tell me they have been on a ketogenic diet (and it’s worked well for them or maybe it hasn’t worked so well for them), only to discover they are not really eating a true ketogenic diet. How do we simplify this way of eating and make it easy for individuals to understand and then stay in ketosis?
How do we create a ketogenic diet that is nutrient dense and also offers the benefits seen in this research. I have major concerns about long-term nutritional deficiencies with a diet of coffee, eggs, poultry, and lettuce (as eaten by the female patient in this case study). It should ideally include plenty of leafy greens, non-starchy vegetables like broccoli, cauliflower, asparagus etc. and healthy fats like avocado, grass-fed butter and coconut oil, together with fermented vegetables and bone broths. I’m also not convinced that coffee should be part of the ketogenic diet, especially if coffee increases your anxiety and affects your sleep.

How do we help individuals make the switch to this way of low carb eating and help them maintain so they don’t feel deprived and are not relying on willpower alone? As you can see from these 2 cases, the diet can be challenging to sustain and slip ups are common. If you are eating enough health fats (and it’s a lot more than you’re used to eating), this typically helps with cravings. If you still have cravings and feel you are deprived and missing out on treats, the targeted individual amino acids offer powerful results: tryptophan (for afternoon cravings), GABA (for stress eating), DPA (for comfort eating), tyrosine (when there is low motivation) and glutamine (for low blood sugar cravings).
Is the ketogenic diet the next big fad or weight-loss trend as we’re hearing in the media? Based on the above research it truly does have impressive therapeutic benefits beyond only weight-loss. So can we see similar benefits with a modified ketogenic diet, using intermittent fasting and/or cycling in and out of ketosis, and even adding in a ‘feasting day’ of carbs?
Who shouldn’t adopt a ketogenic diet? For example: those with the APOE4 gene, women with adrenal and hormone issues, and individuals with thyroid issues and no gallbladder? The question then becomes this: of those suffering with anxiety and depression or another mental health disorder, who doesn’t have one of these issues? And how do we address the keto rash, constipation, fat malabsorption, fatigue, mineral deficiencies and other issues some people experience on a ketogenic diet?

Right now, this is my thinking: as with any nutritional or functional medicine approach, I would say there is no one-size-fits all for who should implement a ketogenic diet (we need to consider the unique biochemistry of each person) and there is no one set ketogenic diet (it will need to be customized for each person).

I’m hoping to get answers to many of these questions on the upcoming Keto Edge Summit (May 7-13, 2018), hosted by ketogenic diet expert, Dr. David Jockers. If you have similar questions, be sure to tune in too. I’m going to reach out to Dr. Jockers for an interview too.

I’m also hoping to do my own interview with Dr. Palmer to discuss his interest in the ketogenic diet for mental health, to learn more about these cases and other patients he’s seen success with. Feel free to post your questions for Dr. Palmer (and Dr. Jockers) here and I’ll be sure to get them addressed. We certainly appreciate Dr. Palmer for sharing these results so we can all learn, and also appreciate his patients for being willing to share their stories.

Please do share if you’ve adopted a ketogenic diet and the benefits you have experienced, and if you experienced any issues. Be sure to share what a typical day’s diet looks like for you.

Wi-Fi is an important threat to human health and may contribute to unresolved anxiety, SIBO, oxalate issues and high cortisol

March 30, 2018 By Trudy Scott 12 Comments

A new paper by Martin Pall, Wi-Fi is an important threat to human health, states the following:

Repeated Wi-Fi studies show that Wi-Fi causes oxidative stress, sperm/testicular damage, neuropsychiatric effects including EEG changes, apoptosis, cellular DNA damage, endocrine changes, and calcium overload.

He states that EMF effects are often cumulative, EMFs may impact young people more than adults and that voltage-gated calcium channel (VGCC) activation plays a role in all seven effects:

Each of these seven is also produced by downstream effects of the main action of such EMFs, voltage-gated calcium channel (VGCC) activation.

Peroxynitrite is a very powerful oxidant leading to major oxidative stress in the body and his landmark VGCC paper covers how peroxynitrite is created:

EMF activation of VGCCs leads to rapid elevation of intracellular Ca2+ [calcium ions], nitric oxide and in some cases at least, peroxynitrite

I’m studying the human threats of Wi-Fi and EMFs in the practitioner ElectrosmogRx course being taught by Nick Pineault, so the timing of this new paper is excellent. Nick’s course is highly recommended too.

I’ll have much more to share once the course is over but this is just some of what I’ve learned so far about the biological impacts of EMFs (other than what is mentioned in the above new paper by Martin Pall):

A contribution to mitochrondrial dysfunction
Increased inflammation
Glutathione depletion
Glutamate excitotoxicty
Break down of the blood brain barrier and other barriers like the gut
Melatonin depletion

And much more – all of which have major implications for mental health (and other health conditions too of course).

My speculations about chronic anxiety, insomnia, benzodiazepine issues, SIBO and oxalate issues

Based on the above and making some extrapolations from the research I am speculating that EMF overload may play a role in the following situations in some susceptible individuals:

Why some individuals have chronic high cortisol and yet nutritional support for the adrenals offers minimal help? And why some individuals continue to experience anxiety and insomnia (due in part to high cortisol and/or low melatonin) despite making all the root cause changes to diet, addressing gut health and addressing nutritional deficiencies? Or why ongoing nutrient support is needed despite following a healthy lifestyle?
Why some individuals on benzodiazepines have such a difficult time with tolerance, physical dependence and tapering, and even continue to experience adverse effects long after their last dose. This is based on extrapolations from research showing “Chronic benzodiazepine administration potentiates high voltage-activated calcium currents in hippocampal CA1 neurons”
Why so many have issues with dietary oxalates (found in nuts, wheat, leafy greens like spinach, strawberries, eggplant, kiwi fruit and other healthy vegetables and fruits) leading to increased anxiety and pain. I’m just starting to look at all the research – here is one paper that discusses the effects of electromagnetic radiation on the rat kidney: “kidney tissue is extremely sensitive to oxidative damage since it is one of the organs involving intense oxidation processes”
Why we are seeing such an increase in SIBO (small intestinal bacterial overgrowth) and why are there so many individuals who cannot resolve their chronic SIBO. I’m still looking for some research linking EMFs and SIBO and/or IBS but Nick writes about this in his book. Is the high use of the cell phone for texting and communicating on social media playing a role since you hold your phone on your lap right by your belly? I did find this interesting research: could oxalate issues be contributing to chronic SIBO?

If you can relate to any of the above and you are now wondering if your Wi-Fi exposure could be playing a role, I’d love to hear from you in the comments. Please share your situation and symptoms and your current Wi-Fi and EMF exposure i.e. what are you being exposed to and for how long each day are you using various devices.

How to start mitigating your EMF exposure

I’ll be sharing more in the next few weeks, connecting some of the dots, digging into the research and sharing all the steps you can take to mitigate your EMF exposure. Here are some tips to get you started right now:

No electric blanket or clock radio next to your bed
Never have your cell phone on in a moving car (you can use Google maps with your cell phone on airplane mode – just do the search first and then put your phone on airplane mode)
Always have your cell phone on airplane mode at night (it’s even better to switch it off completely) and when carrying it in your bag or on your person
Never hold your cell phone to your ear – only ever speak on your cell phone using the speaker or use a hollow-tube headset
Stop texting/reading social media with your phone on your lap (it’s right by your belly and may be affecting your microbiome)
Do not allow children to use your cell phone or iPad or similar smart device unless they are on airplane mode.
Remove Wi-Fi from your home or at least (for starters) switch it off at night
Get rid of your wireless “toys” like wireless keyboard and mouse (I really didn’t want to get rid of mine)
Work on your laptop via an external wired keyboard and work on battery mode (charging it when you’re not working)
Get rid of cordless phones and get a corded phone

Nicolas Pineault is an investigative journalist and is the author of “The Non-Tinfoil Guide to EMFs” (my Amazon link). He is an expert on EMFs and his book is a wealth of knowledge.

I’d love to hear your level of awareness and concerns about the risks of EMFs? And what you currently do to reduce the risk for you and your family? And have you noticed any improvements in health or strange symptoms?

Or are you not concerned?

If you’re a practitioner is this something you discuss with your clients or patients? Have you observed they respond better to your recommendations and heal more quickly?

The Lyme Solution by Dr. Darin Ingels

March 30, 2018 By Trudy Scott 1 Comment

I highly recommend Dr. Darin Ingels, ND new book The Lyme Solution: A 5-Part Plan to Fight the Inflammatory Auto-Immune Response and Beat Lyme Disease. As a functional medicine practitioner, he provides a natural approach to treating Lyme disease that is both comprehensive and designed to each person’s own unique needs i.e. he doesn’t use a one size fits all approach. His uniquely holistic approach to treating this rampant disease, treats both the infection and the resulting autoimmune response. He’s also recovered from Lyme disease himself so he really gets it!

According to the CDC, over 300,000 cases of Lyme are reported every year in the U.S.A.

As you can see, many conditions can mimic Lyme disease, including anxiety and depression.

Many in my community have both Lyme disease and anxiety and many nutritional solutions, such as GABA (a calming amino acid supplement), can ease their anxiety while my client is working with a doctor such as Dr. Ingels in order to address and eliminate the Lyme disease.

Tricia Soderstrom from Abounding in Hope With Lyme shares her Lyme GABA story here: GABA helps with Lyme anxiety (while addressing the underlying disease)

Dr. Ingels shared this with me when I asked about what GABA products he likes and why:

I use DFH PharmaGaba and Allergy Research Liposomal GABA, which also has theanine. Liposomal GABA works beautifully for anxiety and sleep disturbances in my Lyme patients and children with autism. I also love how quickly it seems to affect people, often within 10-15 minutes of taking it.

Including the latest research about the diagnosis and treatment of Lyme, The Lyme Solution provides a path to wellness by strengthening the body’s ability to heal from within. Dr. Ingels suggests an actionable 5-Part Plan to:

Fortify gut health and restore the immune system
Follow a diet that increases immunity and reduces inflammation
Thwart and target an active infection
Identify hidden toxins that worsen Lyme
Lifestyle suggestions to help healing

Here are some of his gut support protocols: digestive enzymes, glutamine, resveratrol, herbs like slippery elm and marshmallow, fish oil and probiotics:

The Lyme Solution is a simple guide for how you can advocate for your own health and use innovative treatments to maintain wellness, using the least invasive ways to facilitate treatment. By following this plan, you can become even stronger than you were before the Lyme and better equipped to manage recurring symptoms.

UPDATE: April 20, 2018 – My actual review

I highly recommend this book if you have Lyme disease or if you suspect that Lyme disease may be playing a role in your ill-health or have chronic anxiety (or another chronic health condition) and have not yet found a solution. I also highly recommend it for practitioners who are both treating Lyme disease patients and those, like myself, who want to really understand all aspects in order to make good referrals for Lyme treatment.

I read it cover to cover in one sitting and could not put it down!

Chapter 1 – An excellent discussion about the problems with long-term antibiotics for chronic Lyme disease and when antibiotics should be used. The chronic inflammatory autoimmune connection is unique to Dr. Ingels’ approach for treating Lyme disease and makes a great deal of sense. The Lyme facts are invaluable: Lyme spirochete going dormant and hiding in scar tissue and lymph nodes; the nymph the most dangerous; Lyme-reactive antibodies form against proteins in the brain, giving rise to neurological symptoms.

Chapter 2 – Covers complex and controversial issues with diagnosis and pitfalls of the various testing that is available. It contains Lyme signs/symptoms and a Lyme questionnaire. It was eye-opening to learn that the bull’s-eye rash is Lyme specific and that changes in handwriting and mixing up words may be a sign of chronic Lyme disease. This is one of my favorite chapters of the book and is very comprehensive.

Chapter 3 – Gut and immune restoring protocols and more on the autoimmune connection. Addressing gut health is key to any condition and Dr. Ingels reiterates that addressing the immune system is key for recovery from Lyme.

Chapter 4 – Immune boosting diet and the importance of alkalinity. This is my least favorite chapter because I’m an advocate of the Paleo diet and have found that when done well with large amounts of vegetables, it is healing and alkaline. (He did connect with me on this and agrees in principle with a Paleo diet that does include plenty of vegetables). I am pleased to see coffee is off the list but would have liked to hear his experiences with intermittent fasting.

Chapter 5 – Covers targeting the infection in a way that doesn’t impact gut flora and undermine the immune system. This chapter has extensive coverage of the herbal protocols Dr. Ingels has found to be effective for his patients: Zhang protocol, his version of the Cowden protocol and others. He goes into great detail for each herb, including products to help with a Herxheimer reaction, as well as the rationale and protocols for breaking up biofilm. It’s also one of my favorite chapters in the book.

Chapter 6 – Cleaning your home and environment and getting rid of toxic chemicals and products, as well as addressing mold. This is also common-sense to address for any condition so it’s great to cover for Lyme.

Chapter 7 – Sleep, exercise and stress reduction. This is also common-sense to address for any condition. I do have a professional difference of opinion for the GABA recommendation for sleep and typically start my clients on much lower doses. I also love GABA for stress and anxiety.

Chapter 8 – Advanced protocols for specific symptoms: mitochondrial issues, neuropathy and balance, low dose immunotherapy, LDN and other approaches where you’ll need to work with a health care provider. Another favorite chapter of mine.

Chapter 9 – Additional lab testing, SIBO, Mast cell activation syndrome and POTS are addressed in relation to Lyme disease. This chapter is enlightening.

The case studies throughout the book reflect the complex nature of Lyme disease and help us get a better understanding about unexpected symptoms, as well as Dr. Ingels’ level of expertise. One such example is Peter’s story: he developed tics but none of the other classic Lyme symptoms, PANS was found and then Lyme disease.

Given that neuropsychiatric symptoms are common in Lyme disease I hope to see more coverage of this in a later edition or follow-up book. I work with individuals with anxiety and underlying Lyme disease is very common, with benzodiazepines and SSRIs commonly prescribed. Using nutritional approaches for the anxiety and/or depression and since it gets to the root cause it’s more effective, plus it lowers the toxic burden and side-effects of added medications. (He also connected with me about this and said he agrees but word-count was the challenge in this first book).

Overall, this book is an excellent resource and I highly recommend it! It offers practical solutions and hope for those who are been suffering with chronic Lyme disease and are seeking a solution.

Learn more and get your copy here on Amazon (my link) or at major bookstores. Get access to a digital version of chapter 1 here.

An “omnivore” like diet or Paleo diet is associated with reduced anxiety and depression

March 23, 2018 By Trudy Scott 6 Comments

A new study published last month, Do patterns of nutrient intake predict self-reported anxiety, depression and psychological distress in adults? SEPAHAN study, reports that

An “omnivore” like diet high in amino acids, cobalamin, zinc, phosphorus, saturated fat, cholesterol and pantothenic acid is associated with reduced psychological disorders.

This was a cross-sectional study, meaning it was a type of observational study design where the outcome and the exposures in the study participants are measured at the same time. The aim was to find an association (rather than causal relationship) between patterns of nutrients intake and psychological disorders such as anxiety and depression.

The study authors had 3846 Iranian adults between 18 and 55 of age complete questionnaires in order to assess their diets and nutrient patterns, as well as psychological factors including anxiety, depression, and overall health in general. This group comprised 1712 males and 2134 females.

The study results

After calculating the daily intakes of 57 nutrients (including individual amino acids,

starch, dietary fiber, simple sugars, different fatty acids, vitamins, minerals, and bioactive substances), 3 nutrient patterns were identified:

1) the “omnivore” pattern

high in individual amino acids, cobalamin, zinc, phosphorus, saturated fatty acids, cholesterol and pantothenic acid

in both women and men, with pyridoxine (vitamin B6) high in men only

2) the “grains and dairy” pattern

high in thiamin, folate, selenium, iron, starch, maltose, betaine, calcium, riboflavin, and niacin

and low in the following

mono-unsaturated fats, vitamin E and polyunsaturated fats

3) “fruits and vegetables” pattern

high in copper, vitamin C, glucose, fructose, potassium, dietary fiber, sucrose, vitamin A, magnesium and vitamin K.

These are the associations that were observed after adjusting for confounding factors:

Men in the top tertile of the omnivore nutrient pattern had lower anxietyand depression scores than those in the bottom tertile
Women in the top tertile of the omnivore nutrient pattern had better overall poor health scores than those in the bottom tertile and had lower odds of psychological distress, such as anxiety and depression.

This type of diet is also referred to as a Paleo or cave-man type of diet. Even though this study was only showing associations and not a cause-and-effect, it’s still very encouraging to see new research in the field of nutritional psychiatry, further supporting the results we see in clinical practice.

What are the mechanisms?

The high amino acids provide the building blocks for the production of our feel-good neurotransmitters such as serotonin, GABA, dopamine and endorphins, with zinc being a key co-factor for making these brain chemicals. The authors share some of the mechanisms for the association in the discussion section of the paper:

Dietary protein intake and also individual amino acid status have been linked to psychological status in previously published studies. For instance, methionine in the form of S-adenosyl-L-methionine, tryptophan and serine were inversely associated to depression. Lysine, arginine, beta-alanine, tryptophan and tyrosine have been shown to have anxiolytic effects. As amino acids are important precursors for neurotransmitters; they might affect psychological condition. Important neurotransmitters like dopamine and serotonin are made from amino acids tyrosine and tryptophan, respectively.

Pantothenic acid is a B vitamin that is key for stress and adrenal health. Low levels of B12 or cobalamin can be associated with both anxiety and depression, as well as fatigue. Both zinc and B12 are common deficiencies, and more so in vegetarian and vegan diets. The authors discuss some possible zinc mechanisms:

zinc has antidepressant-like activities such as up-regulation of the expression of brain derived neurotrophic factor (BDNF) gene
zinc is an antagonist of the glutamate/N-methyl-D-aspartate (NMDA) receptor

Seeing saturated fat and high cholesterol mentioned in favorable terms in a study – both of which are needed for a healthy brain and for good blood sugar control – is always exciting. The authors discuss these possible mechanisms:

low serum total cholesterol may increase the risk of depression and suicide attempts. It is hypothesized that low cholesterol intake might cause a depressed central serotonergic activity which in turn leads to depression.

Here is my addition to the discussion: in our interview on a prior Anxiety Summit, Dr. Kurt Woeller and I discuss the link between low cholesterol and low oxytocin and the role this plays in anxiety, social bonding and depression.

One area I’m a little confused about is the findings on pyridoxine (vitamin B6). They report it was high only in men in the omnivore group, and not in women. As they report, vitamin B6 is also a key co-factor in the serotonin-tryptophan pathway and we know it’s important for alleviating anxiety- related PMS symptoms in women. It’s mentioned in the concluding paragraph for playing a role in the association for both men and women and yet it is not mentioned in the abstract. I’ll report back as I find out more.

Here are some actual real-life results from someone eating this way

I blogged about anxiety and depression success stories on Paleo and grain free diets around this time last year. I shared Andrea’s feedback about her diet-mood results with a grain-free and high fat diet:

I happened upon a fat loss diet that had me cut out grains, most dairy, and sugar while focusing on mostly meat, fish, fats from nature such as butter, olive, and coconut oils. Nuts, seeds, and legumes were allowed too. These rules made it so I had to avoid processed foods. There was one day a week of eating anything.

Within 6 weeks I was shocked that I got much much more than fat loss. My depression, anxiety, mood swings, sleep issues and all but one pesky health symptom disappeared. I was stronger, faster, and felt energy I never remember having.

Have you found benefits with an omnivore or Paleo diet? Less anxiety and depression? Better overall health? More energy? Better sleep?

If you’re a practitioner have you found this approach works with your clients/patients?