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Could a daily moisturizer help to lower markers of inflammation and reduce anxiety, panic, PTSD, phobias and social anxiety?

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Could using a good quality moisturizer on a daily basis help to lower markers of inflammation (proinflammatory markers) and actually help reduce anxiety, panic, PTSD, phobias, social anxiety and other mental health symptoms, plus other chronic health conditions at the same time? Based on a new pilot study, I’m going out on a limb and saying this may well pan out to be true. And there is certainly no harm in making this a daily self-care routine until further research confirms this, certainly because of the other benefits of using a moisturizer.

New study: a skin moisturizer reduces markers of inflammation

Let’s take a look at this new study which reports how using a skin moisturizer actually reduces markers of inflammation in the body: Topical Applications of an Emollient Reduce Circulating Pro-Inflammatory Cytokine Levels in Chronically Aged Humans: A Pilot Clinical Study

Emollients are moisturizers that help keep the skin moist and supple by reducing water loss from the epidermis, the outer layer of the skin.

The study set out to mirror an animal study where skin problems in older/aged mice was tied to elevated markers of inflammation called cytokines. When epidermal function/skin health in the mice was improved, the circulating cytokine levels were reduced:

Thirty‐three aged humans were treated twice‐daily for 30 days, with ≈3 ml of an emollient, previously shown to improve epidermal [i.e. skin] function

Changes in epidermal function and levels of three key, age‐related, plasma cytokines (IL‐1β, IL‐6 and TNFα) were measured at baseline and after treatment.

Circulating levels of proinflammatory cytokines in the body, IL‐1β, IL‐6 and TNFα, were higher in the older adults before the use of the emollient. After topical use, i.e, using the cream on their skin twice a day for 30 days:

circulating levels of IL‐1β and IL‐6 normalized, while TNFα levels declined substantially.

The authors suggest larger clinical trials to confirm this connection between high levels of proinflammatory cytokines and chronic inflammatory disorders and to show how improving skin health by moisturizing may prevent chronic inflammatory disorders such as heart disease, type II diabetes, osteoporosis and Alzheimer’s disease in older adults.

The University of California explains the mechanism:

Our skin starts to deteriorate around age 50 with changes to epidermal pH, hydration, and the permeability barrier, which keeps water in and bacteria and other potential pathogens out. A loss of moisture and breaks in the permeability barrier cause the skin to release inflammatory cytokines. Ordinarily, these cytokines help to repair defects in the barrier, but in aging skin the barrier can’t be fixed as easily, so the inflammatory signals continue to be released, eventually reaching the blood.

This article and the study authors are suggesting this is an issue to be addressed with older adults and with respect to the above chronic diseases, but there is enough research on the role of inflammation on anxiety and other mental health conditions at any age, that this study had me perk up and take notice. Also, if you’re young and not moisturizing or living in a dry climate or have other factors contributing to inflammation (more on that below), could this be happening too? I believe it’s highly likely.

The role of inflammation on anxiety and other mental health conditions

Here is one of the many anxiety-inflammation studies: Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond, reporting that:

heightened concentrations of inflammatory signals, including cytokines and C-reactive protein, have been described in posttraumatic stress disorder (PTSD), generalized anxiety disorder (GAD), panic disorder (PD), and phobias (agoraphobia, social phobia), etc.

And concludes that:

targeting inflammation may serve as a potential therapeutic target for treating these fear- and anxiety-based disorders in the future

Inflammation plays a role in depression too. This paper, Role of Inflammation in Depression and Treatment Implications reports that:

Numerous studies (including meta-analyses) have found elevated peripheral and central inflammatory cytokines and acute phase proteins in depression.

The ongoing inflammation affects neurotransmitters and makes antidepressants less effective:

Chronic exposure to increased inflammation is thought to drive changes in neurotransmitters and neurocircuits that lead to depressive symptoms and that may also interfere with or circumvent the efficacy of antidepressants.

Many approaches for reducing cytokines and inflammation

I do want to address the one statement in the emollient study where they say that “approaches that reduce circulating cytokines are not yet available.” There are, in fact, many approaches for reducing cytokines and inflammation.

In one study vitamin D supplementation improved mood, reduced anxiety and lowered markers of inflammation (CRP and IL-10) in female diabetics who had low levels of vitamin D.

In another study looking at anxiety in women with PCOS (polycystic ovary syndrome), probiotics and selenium improved their mental health and hormonal profiles, lowered markers of inflammation and reduced oxidative stress.

This paper lists a number of underling root causes that cause systemic inflammation and depression: psychosocial or life stressors, poor diet, physical inactivity, obesity, smoking, altered gut permeability (i.e. leaky gut), atopy (a genetic tendency to allergies – this could include gluten sensitivity), poor dental health, sleep issues and vitamin D deficiency.

Of course, these factors may also play a role in anxiety and using a functional medicine and nutritional approach, you can reduce the inflammation and eliminate the anxiety/depression. It’s a matter of finding your root cause/s and addressing them.

Research is also finding that GABA, one of the main calming neurotransmitters, may also have a possible role in “neuroimmune interaction, being involved in the modulation of immune cell activity associated with different systemic and enteric inflammatory conditions.”

Low zinc and low vitamin B6 are also factors in inflammation, and addressing low levels reduces inflammation and eases anxiety such as pyroluria (a social anxiety condition) and low GABA and low serotonin anxiety because zinc and vitamin B6 are co-factors for making these brain chemicals.

The benefit of touch and a boost of oxytocin

I’d like to mention other benefits of using a daily moisturizer – the benefits of touch, massage and a boost of oxytocin:

  • Hand massage and therapeutic touch has been shown to decrease anxiety and make the elderly in a nursing home feel more comforted. If you’re a caregiver to a parent, make daily moisturizing part of your routine.
  • Swedish massage reduces anxiety in ICU patients and improves vital signs.
  • Touch increases the release of oxytocin improving well-being and may also have “applications in neuropsychiatric disorders especially those characterized by persistent fear, repetitive behavior, reduced trust and avoidance of social interactions.”

Adding skin moisturizing to your daily self-care routine

I feel very comfortable saying you now we have a new tool – daily skin moisturizing – to add to your toolbox to help lower your markers of inflammation and reduce anxiety, panic, PTSD, phobias and social anxiety. Let’s use everything at your disposal to heal and feel your absolute best.

It’s something most women (and a few men) are already doing, and this information can give you more reason to continue to do it.

It’s a lovely self-care routine if you’ve not been doing it for some time or have never regularly used a moisturizer. This information can be an incentive to add it back to your daily routine or start doing it.

The biggest problem I see with moisturizing is using toxic chemicals and less than ideal creams on your skin so I reached out to colleagues and my community on Facebook to get input on their favorite home-made and store-bought moisturizers:

In the meanwhile, feel free to share your favorites and what your moisturizing self-care routine is like, and if you get regular massages and use moisturizing creams with love ones. Simply comment below.

Additional Anxiety Resources
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The best food-mood-nutrient topics of 2017

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As we move into 2018, it’s time to recap and share the best of 2017 – from both blog posts and facebook posts. Hopefully these topics have helped you move forward as you address your anxiety symptoms and will help you (and your clients/patients if you’re a practitioner) take even bigger leaps as you move into 2018!

Most popular blog posts

Here are the most popular blog posts of 2017, based on comments and questions. If you have already read one of these and found it interesting at the time of publication, it’s worth a re-read for all the valuable comments/questions and my feedback.

Collagen and gelatin lower serotonin: does this increase your anxiety and depression?

I see everyone raving about gelatin and collagen – and rightly so – they have amazing health benefits. However, no-one is addressing the fact that gelatin is actually used in tryptophan-depletion studies to lower serotonin.

Some people get more anxious and depressed when consuming collagen, some do just fine and some even use it to lower their serotonin. Many need to use it with added tryptophan. I recently made some additional updates to this blog and have more to add so stay tuned for more on this topic.

How much GABA should I use and which GABA product is best?

There is no simple answer! It requires a blog post to provide a good answer because we are all unique, have different needs and these needs can even differ at different times depending on the issue and what is going on in our lives at the moment.

My Kid is Not Crazy and PANS/PANDAS awareness day 2017

PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections) occurs when strep triggers a misdirected immune response results in inflammation on a child’s brain. In turn, the child quickly begins to exhibit life changing symptoms such as OCD, anxiety, tics, personality changes, decline in math and handwriting abilities, sensory sensitivities, restrictive eating, and more.

Anxiety, compulsive thinking, counting behaviors: gluten, tryptophan and inositol

Today I’m going to share my feedback on a question I received on how to approach working with a child with anxiety, compulsive thinking and counting behaviors in the hope it can help you or someone you know (or are working with if you’re a practitioner)

DPA for weepiness, pain and comfort and reward eating

This amino acid is a favorite with so many of my clients because it helps with [weepiness, pain and comfort and reward eating] by boosting your endorphins and when you chew a capsule you feel like you just got a big hug.

How to Beat Anxiety and Resolve Panic Attacks with Targeted Amino Acids: Wellness Mama podcast

I share my wonderful interview with Katie, the “Wellness Mama”. We talk about my favorite topic: How to Beat Anxiety and Resolve Panic Attacks with Targeted Amino Acids, with some extra questions about pregnancy and nursing that I’m not often asked about.

GABA for the physical-tension and stiff-and-tense-muscles type of anxiety

I’m going to review some GABA products for the physical-tension and stiff-and-tense-muscles type of anxiety, and share some additional resources for you….

I share that sublingual is best, do a trial and start low, my favorite GABA products and when it works and when it doesn’t.

Tryptophan for the worry-in-your-head and ruminating type of anxiety

I’m going to review some tryptophan products for the worry-in-your-head and ruminating type of anxiety… Lidtke is the only brand of tryptophan that I recommend simply because I see it work so well and because of quality issues with tryptophan in the past.

I also share when to use tryptophan and when to use GABA, and tryptophan for PMS.

GABA: an amino acid supplement for neurotransmitter support and anxiety relief

I recently attended the first international meeting of International Society for Nutritional Psychiatry Research and was honored and thrilled to present my poster – GABA: an amino acid supplement for neurotransmitter support and anxiety relief Because you were not able to be there, here are the contents of my poster word for word.

How GABA eases agonizing rectal pain and spasms in under 2 minutes

Proctalgia fugax is described as a condition that leads to rectal spasms and sharp fleeting pain in the lower rectum or anus. In some people it can be more than fleeting and is often described as excruciating and agonizing.

I have experienced this awful anal sphincter spasm and pain myself so I want to shine some light on this condition and offer the simplest and most effective solution: oral and sublingual GABA. It works to completely eliminate the pain in 1-2 minutes! And it can also be used to prevent a full-on spasm if you catch it in advance.

Migraines, Anxiety and Antiphospholipid Syndrome: on the Chronic Headache & Migraine Summit

The autoimmune condition called Antiphospholipid Syndrome (APS) is one of many possible contributing factors for both migraines and anxiety.

Cognitive impairment, strokes and livedo reticularis is common.

GABA protects against hypothyroidism caused by fluoride and reduces anxiety

To the best of our knowledge, this is the first study to establish the therapeutic efficacy of GABA as a natural antioxidant in inducing thyroprotection against fluoride-induced toxicity.

GABA for children: ADHD, focus issues, irritability, anxiety and tantrums

My daughter hasn’t been diagnosed with ADHD but has a lot of ADHD qualities. We were having a huge amount of behavior problems as she is getting older (she’s 11). I did some research and went to the health food store and bought a bottle [of GABA Calm]. At this point I was mentally exhausted from all the fighting and drama at home and at school. I was desperate and didn’t want to put her on any hard medication.

She has had amazing behavior at school and at home since giving it to her. She’s almost like different child. GABA has truly changed our life. She’s been taking it for almost 2 months.

Anxiety: when to use GABA and tryptophan and how much to use

When you have anxiety it can be confusing trying to figure out the root cause. I like to start by assessing for low GABA and low serotonin because when you address these with targeted individual amino acids you typically see results right away and feel hopeful (and now have time to look for other root causes like gluten issues, high cortisol, gut issues, dietary changes etc).

But there may still be some confusion about when to use GABA and when to use tryptophan and how much of each of these amino acids to use.

Vulvodynia: oxalates, GABA, tryptophan and physical therapy

I just listened to the webinar talking about oxalates. I was shocked and delighted to hear the mention of the connection between high oxalates and vulvodynia.

Research shows there is serotonin involvement with vulvodynia and SSRIs are often prescribed, as are benzodiazepines. My recommendation is trials of tryptophan and/or GABA.

Seriphos Original Formula is back: the best product for anxiety and insomnia caused by high cortisol

If you have high nighttime cortisol (as measured by an adrenal saliva test) it can cause insomnia and anxiety. Using 1-3 x Seriphos about 1-3 hours before the high cortisol is the best way I know for lowering the high cortisol and providing relief.

The product was reformulated and didn’t work like it used to and then the original formula was brought back.

GABA takes some of the anxiety edge away and now I want to add tryptophan: how do I do this?

I would say this – ask yourself what low GABA anxiety symptoms (this is the physical anxiety) have improved with the GABA and how much (rate each one before – out of 10; and what are they now – out of 10). From your question it sounds like they could improve more – so if we were working together I’d continue to increase GABA before adding something new.

The most popular facebook posts

And here are some of the most popular Facebook posts on TrudyScottAntianxietyFoodSolution (based on comments and shares). Many of these link to other sources like the research or other blogs with additional information. Most of them have a great back and forth discussion on the Facebook post so feel free to join in there.

Canola oil linked to worsened memory and learning ability in Alzheimer’s

Canola oil is one of the most widely consumed vegetable oils in the world, yet surprisingly little is known about its effects on health. Now, a new study published online December 7 in the journal Scientific Reports by researchers at the Lewis Katz School of Medicine at Temple University (LKSOM) associates the consumption of canola oil in the diet with worsened memory, worsened learning ability and weight gain in mice which model Alzheimer’s disease. The study is the first to suggest that canola oil is more harmful than healthful for the brain.

Canola oil is not something I’ve ever recommended and I’m really glad to see this research. You have to read labels because it’s in a lot of salad dressings and processed foods!

Nestle to buy vitamin maker Atrium Innovations for $2.3 billion

The following brands are now owned by Nestle: Garden of Life, Douglas Laboratories, Pure Encapsulations.

This is not good! Other than the fact that the formulations will likely be changed, there is much to be said about Nestle and their ethics.

The Big Vitamin D Mistake

This could lead to a recommendation of 1000 IU for children <1 year on enriched formula and 1500 IU for breastfed children older than 6 months, 3000 IU for children >1 year of age, and around 8000 IU for young adults and thereafter. Actions are urgently needed to protect the global population from vitamin D deficiency.

Do you use a zinc supplement every day?

1) how much and what form? and with or without copper?
2) how did you decide to add zinc (or was it recommended by a practitioner)
3) how did you assess your zinc status (alk phos? zinc challenge/tally? mood symptoms? white flecks on nails? poor digestion? pyroluria questionnaire? blood work? other?)
4) how it helps you? (less anxious? more social? less depressed? less cravings? better digestion? better skin? less aches/pains? better blood sugar control? less PMS/hormone symptoms? better adrenal health? better immunity? other?)

Scary new information about benzodiazepine deaths

The five most frequently occurring drugs found in decedents were ethyl alcohol (5,318), benzodiazepines (5,167, including 1,851 alprazolam occurrences), cocaine (2,882), cannabinoids (2,292), and morphine (2,040).

With teen mental health deteriorating over five years, there’s a likely culprit

In a new paper published in Clinical Psychological Science, my colleagues and I found that the increases in depression, suicide attempts and suicide appeared among teens from every background – more privileged and less privileged, across all races and ethnicities and in every region of the country. All told, our analysis found that the generation of teens I call “iGen” – those born after 1995 – is much more likely to experience mental health issues than their millennial predecessors.

What happened so that so many more teens, in such a short period of time, would feel depressed, attempt suicide and commit suicide? After scouring several large surveys of teens for clues, I found that all of the possibilities traced back to a major change in teens’ lives: the sudden ascendance of the smartphone.

Gabapentin and pregabalin are as problematic as benzodiazepines

Crippling toll of the new valium that’s ruining the lives of MILLIONS

Can you relate to the term high-functioning anxiety?

Busy and in control. High-achieving and perfectionistic. Driven by details and order in a desperate attempt to calm racing thoughts, worry, and the fear that invade every ounce of the mind and body. An over-thinker with a tendency to perseverate, dwell, and stew on everything.

I used to be like this before the panic attacks and it’s a big clue that it’s time to do something about it but too often we push and push and push and then it gets really bad. I would love to be able to reach women (and men) at this stage before it gets really bad!

Great article about squatting and the benefits

How often do you squat? and do you use a device like the Squatty Potty?

Screen time might boost depression, suicide behaviors in teens

A new study finds that teens, especially girls, who spend several hours per day on phones and tablets are more likely to be depressed and have suicide-related outcomes.

When it comes to cravings, addiction and appetite we have this research supporting the use of glutamine

– Glutamine and glutamatergic metabolism is a factor in cravings and alcohol dependence
– A combination of tyrosine, lecithin, glutamine and 5-HTP helped withdrawal syndromes and mental symptoms in detoxified heroin addicts
– Glutamine has been shown to decrease secretion of ghrelin, the hormone that impacts appetite regulation. High levels of ghrelin appear to make high-calorie foods look more appealing.

Why the vaginal mesh scandal could be ‘bigger than thalidomide’

More than 92,000 women had vaginal mesh implants between 2007 and 2015 in England, and about one in 11 is said to have complications. More than 800 of these women are now taking legal action against the NHS and mesh manufacturers.

Please be aware of the dangers of vaginal mesh (and other procedures that use mesh) – it’s something I’ve always warned my clients about and it needs to become common knowledge

Do you take probiotics on a daily basis and do they help? Have you had to stop taking probiotics because of any adverse effects?

Melatonin–estrogen interactions in breast cancer

Individualized protocols in Dr. Nalini Chilkov’s OutSmart Cancer system include melatonin at 10-20mg at bedtime (to match nature’s cycling of melatonin…not for sleep issues) . MANY breast cancer patients have low or aberrant melatonin patterns.

The anti antidepressant. Depression affects 16 million Americans.

One third don’t respond to treatment. A surprising new drug may change that: ketamine.

I’m quite surprised how many women who are smart and savvy when it comes to eating and natural health continue to color their hair (or straighten or perm or treat).

I’m curious if you are one of those people ? And if yes why? Do you know the risks or would you just prefer not to know?

Excellent article on toxic sunscreen ingredients

I have always avoided conventional sunscreens and teach my clients about this but wish more people were aware of these issues. It’s not just sunscreens either…so many skin care products, makeup, hair products and household products have ingredients that are endocrine disrupters, cause DNA and oxidative damage and affect our health – both physically and mentally! What sunscreen do you use?

My favorite protein powder

I love this one because _______. I use it in these ways ______, _______, ________.

Right now my favorite protein powder is a pea protein (made by Nuzest). I love this one because it’s gluten-free, dairy and soy free, GMO-free and is pea only (no other ingredients!). I just found out it’s also available in USA and other countries.

My favorite healthy protein bar

I love it because _______ AND/OR I tried ______ and don’t like it because ________. My clients are always looking for protein bars for a quick healthy snack but so many are loaded with sugar OR don’t have enough protein and fat OR are full of processed soy OR contain a ton of nuts OR aren’t gluten-free.

Thank you for being such a huge part of this community, for sharing your stories and successes and for offering words of encouragement to others in the community. Thank you too, for asking your questions. Keep the questions coming – they keep me on my toes and help me to learn too!

I’d love to hear how the above topics have helped you and what topics you’d like me to cover in 2018, plus which areas you’d like me to take an even deeper dive into.

Vitamin D: anxiety, depression, sun exposure, supplements and optimal levels

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vitamin-d
(image from Vitamin D Day website http://www.vitamindday.net/)

It was Vitamin D Day on November 2nd and it was a day to recognize vitamin D deficiency as a world problem. The day is led by the Vitamin D Society, Vitamin D Council and GrassrootsHealth, non-profit organizations dedicated to spread awareness on the vitamin D deficiency pandemic. According to the Vitamin D Day site:

Researchers agree that at least one third of the world is deficient in vitamin D, and some scientists even think a greater percent of people are deficient in vitamin D.

Why are so many people deficient, you might ask? It’s simple really. We get vitamin D from sun exposure. And now, more than ever, the world’s population lives an indoor lifestyle, avoiding the sun daily.

Doctors are beginning to discover that vitamin D deficiency is a risk factor for many diseases, including heart disease and cancer.

Furthermore, they’re discovering that vitamin D deficiency may make some diseases more severe, like respiratory diseases and autoimmune diseases like multiple sclerosis and lupus. And they’re discovering that vitamin D can be an important piece in the treatment of some illnesses and diseases, including multiple sclerosis, cystic fibrosis, asthma and many other diseases!

Low vitamin D is also a factor when it comes to mental health. Even though this information is not listed on the Vitamin D day site, there is much research supporting the connection:

There is a strong association between low S-25(OH)D and higher negative and depressive symptoms in psychotic disorders.

In women at risk for depression, early pregnancy low vitamin D levels are associated with higher depressive symptom scores in early and late pregnancy.

Participants with higher serum vitamin D (serum 25-hydroxyvitamin D) levels were significantly less likely to report problems with depression and anxiety.

Serum vitamin D status is related to the occurrence of anxiety in post-stroke patients and may be an independent risk factor of [post-stroke anxiety] after 1 month.

Here are eight key factors to know about vitamin D for Vitamin D day:

  1. Vitamin D comes from sun exposure, not your diet.
  2. Scientists and doctors agree that at least a third of the world is deficient in vitamin D.
  3. If you don’t get frequent moderate sun exposure or take a vitamin D supplement, you’re likely deficient in vitamin D.
  4. Moderate midday sun exposure is the best for making vitamin D.
  5. You don’t need to burn to make vitamin D.
  6. Vitamin D supplements are a good option in the wintertime to get the vitamin D you need.

In the northern hemisphere, the sun starts focusing more on the southern hemisphere. The sun’s rays strike the northern hemisphere at a different angle, an angle that isn’t quite as intense as during the summer. In consequence, your body has a harder time making vitamin D in the winter compared to the summer. The further north you live, the more difficult it is to make vitamin D in the winter.

Remember you can always check to see if you’re making vitamin D by looking at your shadow. If it’s longer than you, you aren’t making much vitamin D. And in the winter, your shadow is often longer than you.

Have no fear that you can’t make vitamin D! Vitamin D supplements are a good option in the wintertime. Low-pressure sunbeds and UV light units are also options to help you make vitamin D during the winter.

  1. Vitamin D is important for many things, including your bones, heart, respiratory system, brain [and mental health], and likely cancer prevention.
  2. Consider getting tested for vitamin D, to see if you’re getting enough.

Vitamin D tests are pretty easy. You can ask your doctor to add it to your next routine blood panel, or you can order an in-home test online through the Vitamin D Council.

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(image from Vitamin D Day website http://www.vitamindday.net/)

Here are the vitamin D range guidelines from various organizations and the recommendations from the Vitamin D council:

vitamin-d-2

This blog post by the Vitamin D Council helps you to interpret your results: I tested my vitamin D level. What do my results mean?

When you get your test results you will see a number in units of ng/ml, for example, 50 ng/ml. These are the units that health professionals in the United States use. Elsewhere in the world, vitamin D blood test results are given in units of nmol/l.

  • To convert a test result measured in ng/ml to one measured in nmol/l, multiply the ng/ml number by 2.5. For example, 20 ng/ml is the same as 50 nmol/l (20 x 2.5).
  • To convert a test result measured in nmol/l to one measured in ng/ml, divide the nmol/l number by 2.5. For example, 50 nmol/l is the same as 20 ng/ml (50÷2.5).

This great Sunshine Calendar shows the amount of time needed to produce sufficient vitamin D.

vitamin-d-3
(image from Vitamin D Day website http://www.vitamindday.net/)

And this graphic shows why most of us aren’t getting enough vitamin D and why we need to supplement and get more sunshine exposure.

vitamin-d-4
(image from Vitamin D Day website http://www.vitamindday.net/)

To learn more about vitamin D, please visit Vitamin D Council, Vitamin D Society, GrassRootsHealth and the Vitamin D Day website.

Do you have your vitamin D levels tested at least once or twice a year? Are they in the 40-80ng/ml range?

And do you spend time in the sun and supplement?

Reduced anxiety in forensic inpatients – long-term intervention with Atlantic salmon

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wild-salmon
Wild salmon (picture used with permission: Vital Choice

Seafood is a great source of amino acids, omega-3 fatty acids, zinc, iodine, iron, calcium, selenium, and vitamins B12, A, and D, many of which are beneficial for mood disorders.

Fish in the diet has a positive impact on depression

A number of studies have found that including fish in the diet has a positive impact on depression, especially those that refer to traditional diets (the famous one is by Jacka and colleagues) and the Mediterranean diet (there are a number of studies by Sanchez-Villegas et al). A study from Finland found that the prevalence of depression was lower in countries where consumption of seafood is high.

When it comes to diet and nutrients there is much more research on depression than anxiety, so when my book The Antianxiety Food Solution was published in 2011, I wrote the following:

Given the link between anxiety and depression, it’s possible that seafood consumption could also help reduce the incidence of anxiety.

A study that now shows reduced anxiety with fish consumption

We have a study that now shows this: Reduced anxiety in forensic inpatients after a long-term intervention with Atlantic salmon

In the study, 95 male forensic patients were randomly assigned to one of two groups:

  • a Fish group where they consumed Atlantic salmon three times per week from September to February OR
  • a Control group where they consumed other protein sources such as chicken, pork, or beef three times per week, also from September to February

The paper lists the incidence of the following disorders amongst the study participants (all sexual offenders) who were in a secure forensic inpatient facility in the USA:

Personality disorders (antisocial personality disorder, borderline personality disorder or personality disorder with antisocial traits) were diagnosed among 76% of the participants. Moreover, about 31% of the participants were diagnosed with some kind of anxiety disorder (GAD, OCD, PD or post-traumatic stress disorder) and about 18% were diagnosed with depression (major depressive disorder or depressive disorder). About 31% of the participants had both a personality disorder and an anxiety or depressive disorder.

The study findings

The study participants consumed salmon for 6 months and the study findings suggest that

Atlantic salmon consumption may have an impact on mental health related variables such as underlying mechanisms playing a key role in emotion-regulation and state-anxiety

And that

The present results showed that fatty fish consumption caused changes in HRV [heart rate variability] which is regarded as an essential underlying biological mechanism involved in anxiety and emotion-regulation.

A few interesting factors about this study

  • The salmon was farmed and mercury and dioxin levels were measured. Despite this, mental health benefits and reduced anxiety was observed. I suspect even more favorable results would have been observed had wild salmon been used
  • The authors mention that a longer intervention as in this study i.e. 23 weeks/6 months is likely to lead to better results than a shorter intervention
  • The Fish group had a significant increase in both omega-3 fatty acids: EPA and DHA
  • The authors speculate about how improved vitamin D status in the Fish group may help regulate serotonin production and thereby help regulate heart rate variability and reduce anxiety
  • The study highlights nutritional benefits of fatty fish other than marine omega-3 fatty acids and vitamin D: selenium, iodine, vitamin B12 and high quality proteins. I’d like to add that it is a source of zinc and iron too, both of which are co-factors for making brain chemicals.
  • Although the study found a significant decrease in state-anxiety, it did not find any changes in trait-anxiety (here are the differences in state-anxiety and trait-anxiety). The authors suggest that trait-anxiety may be more difficult to change during a 6-month intervention study. I’d like to add that other concurrent nutritional and biochemical interventions would likely have provided additional mental health benefits. This could include: a gluten-free diet, targeted individual amino acids, addressing dysbiosis, addressing high or low histamine, pyroluria and zinc-copper imbalances and so on.

The authors mention a limitation of the study, in that this group of adult male forensic inpatients may make it difficult to generalize the results to other groups in the population and recommend further similar research in children and women.

I look forward to future research but I feel very comfortable about putting this limitation aside for now, especially with the positive results found with this group of patients with very severe symptoms.

I also feel very comfortable extrapolating these results from salmon to sardines and would expect similar beneficial results. I highly recommend selecting wild salmon or wild sardines rather than farmed.  

If you suffer from anxiety and stress, or any mood disorder, I hope this research is further motivation to eat wild fatty fish a few times a week. How much fatty fish do you eat each week and have you observed mood or other health improvements?

And if you’re a practitioner, I hope this research is a bigger incentive to continue to recommend fatty fish to your clients or patients.

If you’re looking for some great recipes check out this yummy summer salmon pate recipe and this delicious pomegranate olive mint salsa to serve on grilled salmon. Vital Choice, a wonderful source for great quality home delivery WILD fish, has great recipes on their site too.

The Anxiety Summit – Take magnesium and melt your anxiety away

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Dr. Carolyn DeanQuote_Anxiety2

Dr. Carolyn Dean, MD, ND, author of The Magnesium Miracle was interviewed  by host of the Anxiety Summit, Trudy Scott, Food Mood Expert and Nutritionist, author of The Antianxiety Food Solution.

Take magnesium and melt your anxiety away

  • how important is magnesium: enzymatic processes, mitochondria, heart health, anxiety
  • how important is magnesium compared to calcium; and the vitamin D connection
  • the medication fluoride concern and magnesium impact
  • the symptoms of magnesium deficiency
  • why we are deficient in magnesium
  • dietary sources of magnesium and why diet is often not enough
  • how to test your magnesium level

Here are some snippets from our interview:

If your magnesium is low, your adrenal glands, which require a lot of magnesium, get kind of trigger-happy. And you can start getting adrenaline surges when you’re under stress, blood sugar can go low and you think you’re having an anxiety attack or a panic attack.

Now, your cholesterol depends on a magnesium enzyme to balance cholesterol. If you have too much, it brings it down; if you have too little, it brings it up. It’s done through the mechanism of magnesium. But the statin drugs kill that particular enzyme! And, as well, they cause more magnesium deficiency because many of the statin drugs actually have a fluoride molecule attached, and that fluoride molecule will bind up more magnesium.

Here is one of the 2014 studies we mentioned: Effect of oral magnesium supplementation on physical performance in healthy elderly women involved in a weekly exercise program: a randomized controlled trial

Daily magnesium oxide supplementation for 12 wk seems to improve physical performance in healthy elderly women. These findings suggest a role for magnesium supplementation in preventing or delaying the age-related decline in physical performance.

Here’s the blog post: When magnesium makes me worse  It also has information about magnesium RBC testing with RequestaTest.com and fluoride in medications.

This is the last study Carolyn mentioned – Magnesium deficiency induces anxiety and HPA axis dysregulation: modulation by therapeutic drug treatment.

Overall, the present findings demonstrate the robustness and validity of the Mg(2+) deficiency model as a mouse model of enhanced anxiety, showing sensitivity to treatment with anxiolytics and antidepressants. It is further suggested that dysregulations in the HPA axis may contribute to the hyper-emotionality in response to dietary induced hypomagnesaemia.

Carolyn’s gift 4 Weeks of 2 Year Wellness Program PLUS Invisible Minerals

If you are not already registered for the Anxiety Summit you can get live access to the speakers of the day here www.theAnxietySummit.com

Breast Cancer Awareness: don’t be driven by fear

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DrNalini Chilkov’s new book
Dr. Nalini Chilkov’s new book

October is Breast Cancer awareness month so here are 7 resources to keep you informed, hopeful and inspired to take charge of your overall health and breast health – for prevention and healing – and no more fear!

#1 Reduce stress in your life. Here is a blog post I wrote in 2010 with information from my colleague Ellyn Hilliard: 10 Unique Ways to Support You During Breast Cancer Awareness Month

Reduce the stresses in your life. Calm the nervous system. Meditate, go on a walk…

Start to look at chemicals in your life. Find natural alternatives to cleaning products.

#2 Exercise to prevent cancer and have fun at the same time

up to a third of breast cancer cases in Western countries could be avoided with a nutritious diet and exercise

If exercise is a chore, find something fun to do and it will be a totally different experience

#3 Be aware that a lot of pinkwashing goes on – it’s quite awful how people are being taken advantage of. And know there is so much you can do that is healing and preventative. You can read more here: Pinkwashing for the cure (ridiculous!) or green for prevention?

Pinkwasher: (pink’-wah-sher) noun. A company or organization that claims to care about breast cancer by promoting a pink ribbon product, but at the same time produces, manufactures and/or sells products that are linked to the disease.

Helyane Waldman’s book “The Whole-Food Guide for Breast Cancer Survivors: A Nutritional Approach to Preventing Recurrence”

Rebecca Katz’s “The Cancer-Fighting Kitchen: Nourishing, Big-Flavor Recipes for Cancer Treatment and Recovery”

#4 Ann Louise Gittleman, author of The Fat Flush Diet and Get the Sugar Out, just posted a great blog on how to become a breast health warrior

Raise your daily Vitamin D intake (D is like a hormone rather than a vitamin) to at least 1,000 – 4,000 IU to reach a level of at least 52 ng/mL. Women with serum levels at

Get the Sugar Out! Plain and simple, cancer feeds on sugar which is known to immobilize white blood cells for up to five hours.

#5 Dr Nalini Chilkov is my cancer referral source and she has a new cancer booklet called 32 Ways to OutSmart Cancer. It has beautiful back-to-basics advice about eating nourishing nutrient-dense, antioxidant- and polyphenol-rich real whole food. I especially like the section on herbs and spices and love the chapter on gratitude. Here is a yummy salmon recipe from her blog.

#6 Be hopeful and optimistic. My colleague Fran Sussman shares her journey and story of recovery from breast cancer in this article called I am a breast cancer survivor: There is hope. Fran will be offering six-week support classes for women diagnosed with breast cancer starting in December.

I’ve come through it, with great resilience and rebounding health. I feel better than ever post-breast cancer, at age 60. I am healthy; my doctors concur.

What can you do for prevention? Support your body with optimal nutrition, exercise, sleep and hydration. Use nutrition to minimize inflammation and insulin resistance.

 Acknowledge and work with your fear, but don’t be driven by it.

#7 And my final piece of advice is stated so beautifully by Fran: “Acknowledge and work with your fear, but don’t be driven by it.” Anxiety and depression is very common in people who have been diagnosed with cancer.  This is understandable, but I encourage you to look for and get support in this area too, so you are not driven by your fear.

You may need to address low GABA levels, keep your blood sugar stable with good quality protein at breakfast, support your adrenals, and drink calming carob instead of coffee.  There is so much you can do.

If you’re looking for more great resources for your healing journey, I invite you to join us on The Anxiety Summit, Nov 3-16, and learn more about nutritional and natural solutions for anxiety.  The topics our expert address will also lead to improved overall health, improved heart health and will help with cancer prevention too.