GABA

Perimenopause and menopause: low GABA, pyroluria and the adrenals

March 16, 2019 By Trudy Scott Leave a Comment

As you go into perimenopause and menopause you don’t have to settle for increased anxiety, dull moods, depression, a foggy brain, a flabby belly, night sweats, insomnia, fatigue, low libido, weight gain and the bone loss that so “common” and “accepted” with getting older.

There are natural, effective and easy-to-implement solutions to balance your hormones at any age!

My perimenopausal symptoms hit with a vengeance in my late 30s. The stress that I was experiencing at work, together with all the hormone changes and what I call my “perfect storm” of gluten issues, heavy metals, low GABA, low serotonin, low zinc, adrenal issues, vegetarian diet, candida, pyroluria and leaky gut, all worked together to cause my anxiety and panic attacks.

I didn’t settle and as soon as I used GABA and tryptophan the anxiety and panic attacks stopped and I could take a step back and work on all the other underlying issues, without all the overwhelm.

I share my story in my interview on the Perimenopause Summit with summit host Dr. Michelle Sands, and go into great detail about how to use the amino acids in the most effective way to ease anxiety, worry, fear, negative self-talk, ruminations and overwhelm.

I also share a study about tryptophan easing PMS symptoms in just 3 cycles, as well as some of my other tips for PMS symptom relief (think liver support).

I also talk about a topic that no-one is addressing and yet there is such a simple solution for this excruciatingly painful condition called proctalgia fugax. You may not have heard this term but if you have you know it! In the medical literature it is described as “a condition that leads to rectal spasms and sharp fleeting pain in the lower rectum or anus.” Sublingual GABA works miracles in a few minutes).

My interview – Amino Acid Therapy for Anxiety

Problems with commonly prescribed anti-anxiety meds
How food affects mood
Right and wrong way to use amino acid therapy

Unfortunately, hormone and women’s health issues are incredibly misdiagnosed and misunderstood, leaving many women feeling hopeless, broken and stuck.

Dr. Michelle gets all this because she was also there, in her 20s with irregular and absent periods, mood swings, joint pain, infertility, low libido, digestive issues and insomnia. She was told her ovaries had failed and to manage her symptoms for the rest of her life with birth control pills, antidepressants and other medications. So, she found a better way — a natural way to help her body heal itself — and she’s here to teach you how to do the very same, no matter whether you’re in your 20s or decades older!

The pyroluria perimenopause connection

There are little known connections between pyroluria (a social anxiety condition) and perimenopause.

The nutrients, zinc, vitamin B6 and evening primrose oil, eliminate the social anxiety symptoms and have a direct tie in to perimenopause because these same nutrients:

are needed to make neurotransmitters like GABA and serotonin
are also are needed to make our sex hormones (and help so much with PMS and perimenopausal hormone imbalance)

In my interview with Dr. Michelle I also share how I discovered I had pyroluria before I even knew what pyroluria was. I was in perimenopause and had terrible PMS. I read Ann Louise Gittleman’s wonderful book Before the Change: Taking Charge of Your Perimenopause (my Amazon link), and she recommended zinc, vitamin B6, and evening primrose oil for PMS symptoms. Once I started taking these nutrients I had fewer hormonal issues and they helped so much with my social anxiety.

A few years later when I was working with clients with pyroluria and I looked at the pyroluria questionnaire I thought: “that looks like me, maybe I’ve got this too!” I did the urine test and I discovered that I have pyroluria.

In my interview I talk about :

the pyroluria-introvert connection and why I believe there is a nutritional aspect to introversion and it’s not purely a personality trait
the pyroluria-Lyme connection and how Klinghardt feels that Lyme Disease cannot be treated until the underlying pyroluria is addressed

Be sure to also tune in to Ann Louise Gittleman’s interview. Her discussion about zinc and copper is a perfect complement to my interview.

Ann Louise Gittleman, PhD, CNS: Is Perimenopause a Mineral Imbalance?

Do you have toxic levels of this mineral (copper)?
Best way to test mineral imbalance
Overcoming nutrient and mineral imbalance

Adrenal health is so important during perimenopause

Adrenal health is so important during perimenopause. This is covered in this interview – Adrenals are a Perimenopausal Gal’s Bestie with Marcelle Pick MSN, OB-GYN, NP. She covers the following:

Role of the adrenal glands in hormone balance
Causes and consequences of adrenal burnout
Caring for your adrenals.

And shares these gems:

Prior to menopause about 15% of our sex hormones are produced by our adrenals and after menopause it’s 30% – this is why adrenal health is so important!
When you are stressed the adrenals will make cortisol at the expense of estrogen and progesterone

She also talks about how we handle stress impact the adrenals and why it’s so important to work on lifestyle changes. One great example she shares is this: “are we a perfectionist and do we expect too much of ourselves?”

I’d like to add to this and say that the first step is recognizing that you are a perfectionist and reminding you that perfectionism is a classic sign of low serotonin. That way you can consider using the amino acids tryptophan or 5-HTP to say goodbye to perfectionism and ease some of your stress.

I talk all about low serotonin in my interview but want to help you make this connection as you listen to Dr. Marcelle’s and my interviews.

Dr. Marcelle also discusses what to eat, some of her favorite adaptogenic herbs for the adrenals, exercise advice (and why to do less when you are healing your adrenals) and the effects of childhood trauma.

Do let us know if any of this resonates with you and feel free to post questions in the comments below.

Mindd 2019: The cell danger response and microbiome; and microchimerism and pregnancy

March 15, 2019 By Trudy Scott 15 Comments

Today’s blog highlights two interesting and very different topics that can impact both your mental and physical health: The cell danger response: inflammation, the microbiome and digestion; and microchimerism and how pregnancy can change the health of a mother in unintended ways.

I love to share resources after I’ve attended a conference but today I’m switching it up and sharing resources before the conference for three reasons: 1) to get you fired up and excited about attending in person (or on the Livestream) 2) to share in case you can’t attend in person (or via Livestream) and 3) to highlight the amazing work that the Mindd Foundation is doing via the Mindd Forum 2019, which will be in Sydney, Australia, March 23-24, 2019.

There’s also a giveaway of 2 free tickets to the Public stream (in-person or livestream) so read on below to see how to enter.

The cell danger response: inflammation, the microbiome and digestion

The cell danger response can cause increased inflammation and have direct impacts on the microbiome and digestion. The Cell Danger Response (also known as CDR)

is the intracellular response to stressors, viruses, chemicals or toxins and any foreign particles that come into the human system that need to be expelled. If the cell danger response is constantly being activated and is defective, it may cause a heightened prevalence and severity of inflammation.

The above article highlights the effects on the cell danger response on the microbiome, digestion and nutrient absorption, with ramifications for anxiety, depression, ASD (autism spectrum disorder), ADHD (attention deficit hyperactivity disorder) and many other conditions. Here are some highlights of what the CDR can impact the lower part of the colon

alter disaccharide metabolism, causing the lower/distal bowel to receive a more significant number of simple sugars and change carbohydrate digestion
alter the cells that line the intestines leading to differences in how amino acids are processed, affecting production of neurotransmitters such as GABA, serotonin and dopamine, with consequences for both your brain and gut health

Dr. Robert Naviaux coined the term CDR and will address these links in detail and explain current research with regard to the CDR, cellular healing and how to incorporate these concepts into practice. He will address the role this plays in the healing cycle and treating chronic disease, and specifics on CDR as it applies to understanding Chronic Fatigue Syndrome. His masterclass series is titled: Cellular Pathways for Chronic Disease Recovery.

According to Mindd, three of Dr. Robert Naviaux’s research publications were the most frequently downloaded papers in the journal Mitochondrion in the last 90 days, so this gives you an idea on the relevance of this topic.

Dr Nancy O’Hara also has a helpful explanation of the CDR here cover Clinical Applications of Dr. Naviaux’s research, together with Dr. Elizabeth Mumper.

It’s a pretty complex topic and I’ve been trying to get my head around it for some time. I blogged about some of his early research on CDR and the dramatic effects of a single dose of suramin on “social communication and play, speech and language, calm and focus, repetitive behaviors and coping skills” in 10 boys, ages 5 to 14 years, all diagnosed with autism.

What does all this mean for you?

Could the CDR be a factor in your chronic unresolved SIBO (small intestinal bacterial overgrowth)?
Could there be applications for anxiety for you if you have tried ALL the nutritional/biochemical approaches and are still not seeing symptom resolution?
Could addressing the CDR help you if you’ve been harmed by benzodiazepines, SSRIs and/or fluoroquinolones and can’t take any supplements or can only tolerate very small doses?
Could addressing the CDR help when you have a combination of many stresses like past or recent trauma, genetic defects, heavy metals, mold and Lyme, as well as gut issues and nutritional imbalances?

We clearly have much to learn in this area and I’m excited to hear more from these practitioners.

Microchimerism and how pregnancy can change the health of a mother in unintended ways

Pregnancy can change the health of a mother in unintended ways, sometimes causing harm and in other instances saving the mother’s life. Microchimerism is the “two-way implantation of cells between a mother and fetus.”

Approximately 50-75% of women carry immune cells derived from their fetus after giving birth. Not only that, but the offspring can also hold onto maternal cells too. The fetal cells present in a mother can be apparent for years after giving birth, and their role in human health is currently being investigated. Research is also evaluating the likelihood of whether an older sibling/previous pregnancy can pass cells to a current fetus of a different pregnancy.

The majority of research on microchimerism has investigated its potential to cause harm. This is due to a 1996 paper hypothesizing the link between microchimerism and the cause of autoimmune conditions. However, the connection between microchimerism and positive health outcomes has been receiving attention in the last few years. This is partly due to detecting the capability of mammals to save their mother’s lives by providing cells that are repairing tissue, including bone marrow, to replace dysfunctional cells.

While the mechanism of action is currently unclear, it is understood that microchimeric fetal cells can provide repair processes within maternal tissue, via cellular differentiation.

Leah Hechtman will be speaking at the Mindd Forum 2019 on Microchimerism, mRNA and Parental Wisdom. She will review the understanding of how pregnancy can change the health of a mother in unintended ways and “how we can influence unique genetic pathways to improve the health of future generations.” Read about Leah and more about this fascinating topic in the MINDD article on microchimerism.

Ideally, attend the conference in person. These topics will all be presented as part of both the Public stream and the Practitioner stream, and will also be available via Livestream – at the Mindd Forum 2019 (links below).

Here are all the links

The cell danger response and the microbiome – what’s the link?

What is the Cell Danger Response? with Dr. Nancy O’Hara

A new outlook on Microchimerism

Practitioner stream link

Public stream link

You can find the Mindd Foundation on facebook here.

Drawing to win a ticket to the Public sessions (2 tickets to be won) and 10% discount

If you’d like to be entered into a drawing to enter a ticket to the Public Stream (in-person or livestream):

Comment below and share why you’d like to attend/listen in and what interests you about any or all of these topics
AND share this blog with a friend, colleague and/or on social media. Be sure to mention where you shared it when you comment.
AND let me know if you’d like to attend the Public track in person or do the livestream Public track

I have 2 tickets to give away and I’ll announce the winners on the blog Monday March 18 at 10pm PDT (USA) which is Tuesday March 19 at 4pm AEDT (Australia), and will email you directly if you’re a winner.

As a Mindd Ambassador, I am also thrilled to be able to offer a 10% discount to my community. Use the promotional code TRUDY10 at checkout to receive this discount (this is for both the practitioner and public tracks and the livestream).

Can you see any applications of the above for your health personally or for someone in your family, or a client/patient?

Feel free to post your questions here too and I’ll do my best to try and address them.

And don’t forget to comment and share the blog for a chance to win a ticket to the Public stream!

I have issues with perimenopausal anxiety a couple of weeks per month and don’t want to turn to SSRIs.

March 8, 2019 By Trudy Scott 3 Comments

My challenges with anxiety have been hormonal. I’ve had issues with both postpartum anxiety and now perimenopausal anxiety a couple of weeks per month as I’m approaching menopause. I don’t want to turn to SSRIs but some days are pretty miserable and most other days I feel fine. Any info you have to share regarding this topic or any natural solutions would be of great interest.

When I’m working with a client who reports symptoms like this we start with serotonin and GABA support; determine if they have low zinc, low vitamin B6 and low iron. I also always ask the question: are you on the birth control pill (now or in even in the past).

I’ve blogged about much of this in the past so I’m going to share snippets and blogs for further reading.

Serotonin support with tryptophan for immediate worry-type anxiety relief

In a study published in 1999, A placebo-controlled clinical trial of L-tryptophan in premenstrual dysphoria, tryptophan was found to reduce symptoms of PMS when used in the luteal phase or second half of the cycle (i.e. after ovulation).

This is very typical when I’m working with someone with both PMS (premenstrual syndrome) and perimenopausal anxiety, depression, irritability and mood swings. It typically takes 2 to 3 cycles for an amino acid like tryptophan to have an impact on the cyclical nature of your perimenopausal symptoms.

However, tryptophan does typically start to work right away on the less severe anxiety and mood symptoms assuming you find the ideal dose for your needs. I use the trial method to help my clients figure this out.

When you boost serotonin you also reduce the worry-in-your-head and ruminating type of anxiety, and end to panic attacks and phobias, a boost of confidence, no more depression and negativity, imposter syndrome that is no more, an end to your anger issues and irritability, an improvement in sleep and no more afternoon/evening cravings for something sweet.

You can read more about tryptophan here: Tryptophan for the worry-in-your-head and ruminating type of anxiety

GABA support for relief from tension-type anxiety

During perimenopause progesterone is often low and when it is low, we can expect GABA to be low too. Research confirms low GABA and high glutamate-glutamine in premenstrual dysphoric disorder (PMDD) and that shifting hormones may lead to dysregulation of GABA which contributes to HPA axis dysfunction. The HPA (hypothalamic pituitary adrenal) axis is your stress response system and when it’s not functioning well you are more susceptible to the effects of stress and more likely to feel depressed and anxious.

If your GABA levels are low you will feel increased physical tension and insomnia. The amino acid GABA, opened on to the tongue, can provide calming results within minutes.

Dee likes the instant calm and compares how it worked as well as Xanax had worked for her in the past:

I have taken Xanax in the past for panic attacks. My functional medicine doctor suggested this product as I wanted a natural product. I was amazed how it works just like the Xanax did – instant calm feeling within 10 mins of taking 2 capsules. I use them as needed when I am having heightened stress and anxiety.

Low zinc, low vitamin B6 and/or low iron?

Low iron/ferritin is common if you’re still having a period and it’s one of the important -cofactors for making serotonin, thyroid hormones and the sex hormones. Low iron, together with low vitamin B6 plays a role in anxiety and panic attacks. In one study premenopausal women who had been admitted to the emergency room with panic attacks were found to have both low iron and low vitamin B6. I have an entire blog post on this topic here

The other key co-factor for making serotonin is zinc. You’ll want to look into and address pyroluria if you feel more anxious in social situations like family gatherings, going to church events or community picnics, or even while doing business networking or in work meetings. The key nutrients for pyroluria are zinc and vitamin B6 and both help with PMS and perimenopausal anxiety, and hormone balance.

Are you on the birth control pill?

I recently reviewed Beyond the Pill A 30-Day Program to Balance Your Hormones, Reclaim Your Body, and Reverse the Dangerous Side Effects of the Birth Control Pill by Dr. Jolene Brighten.

If you currently on the pill or have been in the recent past read the above review and get the book to give you an excellent understanding of what may be going on with your body.

Dr. Jolene shares that mood disruption is common and mentions a study in the Journal of the American Medical Association which reports the following:

women who began the pill were more likely to be prescribed an antidepressant – which means it contributes to a bit more than moodiness

She writes in great detail about Post–birth control syndrome (PBCS) which is “is a constellation of symptoms women experience when they discontinue hormonal birth control.” She has found the symptoms of PBCS typically occur in the first 4-6 months after stopping the pill. As well as mood swings and anxiety, you may also experience heavy bleeding or no period, acne, headaches, infertility, pill-induced PCOS (polycystic ovarian syndrome), hypothyroidism, gut issues and even autoimmune symptoms.

You also want to reduce your stress levels. Here are some ideas for you:

Get into nature and experience the incredible benefits of forest bathing
Do some bird-watching in your backyard or at a nearby park: People living in neighborhoods with more birds, shrubs and trees are less likely to suffer from depression, anxiety and stress
Get outside and start bouldering or go and “play” in a climbing gym: A growing body of research suggests that bouldering, a form of rock climbing, can help build muscle and endurance while reducing stress

All the above is a great starting point. You also want to consider adrenal support if needed; and support liver health, together with dietary changes, addressing gut health and thyroid health, getting toxins out of your life and figuring out whatever your own root causes may be.

Here is the link to the amino acids and pyroluria supplements I use with my clients.

Have you found that any of the above has helped you with your PMS or perimenopausal anxiety?

Do you have any stress-relief tips to share with other women who find themselves so stressed out at this age?

Feel free to post questions here too.

Tulsi or holy basil: adaptogenic herb for adrenal support, anxiety and anti-stress effects

March 1, 2019 By Trudy Scott 4 Comments

One very effective approach for supporting the adrenals, reducing anxiety and providing general anti-stress support is using a herbal adaptogen. One of my favorite herbal adaptogens and one that I have found to be very effective and well tolerated by my clients is tulsi, also known as holy basil or the “Elixir of Life” in Ayurveda. I also really like rhodiola. ashwagandha and licorice root but we’ll cover these in another blog.

As stated in this 2017 paper, The Clinical Efficacy and Safety of Tulsi in Humans: A Systematic Review of the Literature

Tulsi, also known as holy basil, is indigenous to the Indian continent and highly revered for its medicinal uses within the Ayurvedic and Siddha medical systems. Many in vitro, animal and human studies attest to tulsi having multiple therapeutic actions including adaptogenic, antimicrobial, anti-inflammatory, cardioprotective, and immunomodulatory effects.

The above paper is a review of the literature and the 24 studies that were included, reported favorable therapeutic effects of tulsi for humans and no significant adverse effects. Only one clinical trial reported mild nausea that lasted a short while.

The authors conclude that the outcome of this review

reinforces traditional uses and suggests tulsi is an effective treatment for lifestyle-related chronic diseases including diabetes, metabolic syndrome, and psychological stress.

With regards to psychological stress, three of the clinical studies reviewed

reported significant reduction in anxiety and stress levels with higher doses of tulsi given over a longer time period.

The positive effect of tulsi on mood was demonstrated … with two studies reporting reductions of 31.6%–39% in overall stress-related symptoms in patients with psychosomatic problems compared to a control group.

In two of these stress studies the dosage ranged from 300mg to 400mg 3 x day and was taken either before or after a meal. In one stress study, 3g (3,000mg) twice a day was used. In all the stress/anxiety studies improvements were observed in 4-12 weeks.

The review also looked at studies on metabolic disorders i.e. type 2 diabetes with “measures of blood glucose, lipids, and blood pressure” and studies on immunity, all showing benefits. In one of the immunity studies, the participants were given 10g (10,000mg) /day for viral hepatitis and symptoms all improved within 2 weeks. I’m sharing this so you can see that the dosage varies depending on the condition and severity of symptoms.

Adrenal support, anxiety, depression and radiation-protection

Here are some additional animal studies that support the use of holy basil or tulsi for adrenal support, for easing anxiety and even depression, and for the anti-stress effect it offers:

Anti-stress Activity of Ocimum sanctum: Possible Effects on Hypothalamic-Pituitary-Adrenal Axis

found to be effective in the management of stress effects, and anti-stress activity could be due to inhibition of cortisol release

Effects of Ocimum sanctum and Camellia sinensis on stress-induced anxiety and depression in male albino Rattus norvegicus

With all the WiFi we are exposed to and the fact that research is now showing that EMFs (electromagnetic frequencies) are likely playing a role in anxiety, depression and ADHD, I’m really pleased to see there are also some animal studies on tulsi being protective against radiation.

Consuming tulsi tea on a daily basis

The review paper above mentions

the Ayurvedic tradition of consuming tulsi on a daily basis

and an easy and delicious way to do this is to drink it as a herbal tea.

Next time you’re ordering your amino acids and pyroluria supplements from my online store with Fullscript, be sure to add a few boxes of Organic India tulsi tea to your shopping cart. This way you can enjoy the healing and anti-stress benefits of tulsi together with the many other herbs included in their teas.

The Lemon Ginger Tulsi has been a long-time favorite of mine and is wonderful when flying to counter motion sickness. Based on the radiation research I uncovered when writing this blog. I’m thrilled I’ll be getting those benefits when flying too. I also enjoy the Peppermint Tulsi early in the day and have recently found a new favorite, the Tumeric Ginger Tulsi (not pictured below). Just so you know, you can also find the herbal teas in most health shops and natural food markets.

The adaptogenic Tulsi-Holy Basil product

Organic India also carries the wonderful adaptogenic Tulsi-Holy Basil product which is taken as a supplement. This is an option if you’re not a herbal tea drinker and/or you need some additional support.

If you’re interested in purchasing the tea or Tulsi-Holy Basil product, you can go to my online store with Fullscript, and simply search for “tulsi”.

How do I use tulsi with my anxious clients?

Where does recommending the tulsi herbal teas and/or the Tulsi-Holy Basil supplements fit in with the dietary and nutritional protocols of my anxious clients?

If you have stress in your life (and who doesn’t?!), drinking the tulsi herbal tea on a daily basis is beneficial. You can mix-and-match with other naturally caffeine-free and healing herbal teas such as rooibos
If you have done adrenal testing and cortisol results are outside of the reference ranges (either high or low) drink the herbal tea and use an adaptogenic herbal supplement such as tulsi (or rhodiola, licorice or ashwagandha), together with a B-Complex, extra vitamin C and extra pantothenic acid
Assess for low serotonin and low GABA anxiety with the questionnaire and do trials of amino acids for the low GABA physical anxiety and/or tryptophan for the worry-in-the-head anxiety
If you are tapering from a benzodiazepine and are not able to initially tolerate high doses of GABA, tulsi is often gentle enough to provide some additional healing support. Research shows the immune modulating effects of tulsi may be mediated by GABAergic pathways).
Make all the dietary changes and address gut health, blood sugar control, low levels of various nutrients like low zinc, reduce stress etc.

Organic India’s ethic and mission

I really love that Organic India works “with thousands of small family farmers in India to cultivate tens of thousands of acres of sustainable organic farmland”, the fact that their “farmers and tribal wildcrafters are educated in organic and regenerative agricultural practices”, and that they have global wellness as part of their bigger mission.

I would like to disclose that Organic India has sponsored me on a number of occasions, providing samples of herbal tea for me to share at conferences such as IMMH. I’ve blogged about this in the past thanking Organic India and other companies.

I do also want to mention that the review paper discloses that one of the authors, Professor Marc M. Cohen, “receives remuneration as a consultant and advisor to Organic India Pty. Ltd., which is a company that manufactures and distributes tulsi products. This article is the independent work of the authors and Organic India did not have input into the article’s content or the decision to publish it.” I appreciate this disclosure.

Do you drink tulsi tea on a regular basis and have you seen the anti-stress and calming benefits? If you drink Organic India tea, which one is your favorite one?

Have you used tulsi or holy basil in supplement form as an adaptogenic herb and what benefits have you observed? Have you used it while tapering from a benzodiazepine?

If you’re a practitioner do you use tulsi with clients/patients or recommend tulsi tea?

Feel free to post questions here too.

The Antianxiety Food Solution online supplement store at Fullscript

March 1, 2019 By Trudy Scott 1 Comment

Fullscript is my online supplement distributor. I have set up an account with them to make it convenient for my clients and those in my online community find quality professional grade supplements

In order to purchase from Fullscript you will need to first set up a customer account under my practitioner account. There is no charge for this and you only need to do this once.

I have thoroughly researched and vetted the products I recommend because, as you know, quality is key when it comes to supplements just as it is key when it comes to food. That being said, formulations do change from time to time, so please don’t hesitate to let me know if a product has changed or is no longer available.

Fullscript carries everything I recommend except Solaray Optizinc (which you can purchase at your local health store).

Here are some tips on how to find products in Fullscript (once you’ve set up an account):

Look under “Product Category” and select “Shop by Dispensary Categories.” You’ll see categories such as Adrenal Support, Amino Acids, Anxiety, Basics, Candida, Cognition, Liquid and Powder Options, Pyroluria and so on OR
If you are doing the online group program Amazing Amino Acids for Eliminating Anxiety look under Class 1, Class 2, Class 3, Class 4 and Class 5 for the recommended products for each of the five classes OR
You can simply use the search feature to find the product/s by name or brand (sometimes you have to go to the brand and then search for the product name)

You can also find information here about the amino acids and pyroluria supplements I use with clients.

And some product-specific blogs about some of the above amino acids:

Create account

If you do already have a Fullscript account, simply click the button above to place your new order or

Unfortunately, they do not yet ship internationally.

Beyond the Pill by Dr. Jolene Brighten – my book review

February 15, 2019 By Trudy Scott 2 Comments

I really wish this book – Beyond the Pill A 30-Day Program to Balance Your Hormones, Reclaim Your Body, and Reverse the Dangerous Side Effects of the Birth Control Pill by Dr. Jolene Brighten – was available when I was in my 30s and on the pill.

Dr. Jolene mentions a study in the Journal of the American Medical Association which reports the following:

women who began the pill were more likely to be prescribed an antidepressant – which means it contributes to a bit more than moodiness.

This was not a small study and included over one million women.

Symptoms caused by the pill and the damage it does to your body

This book, Beyond the Pill, provides a comprehensive list of symptoms caused by the pill:

hormonal confusion: missing or irregular periods, light or heavy periods, short cycles, infertility, headaches
digestive problems: leaky gut, gut dysbiosis, inflammatory bowel disease
energy reduction: fatigue, adrenal and thyroid dysfunction
skin issues: hair loss, dry skin
mood disruption: depression, anxiety
lady part disturbance: low libido (Oh, hell no!), vaginal dryness, chronic infection, pain with sex
vitamin, mineral, and antioxidant depletion (such as folate, B12, and magnesium) (I’ll add vitamin B6 to this list too – it is mentioned elsewhere in the book)

The pill does further damage to your body and also:

intensifies the risk of blood clots, which lead to strokes
increases the risk of breast, cervical, and liver cancers
increases the risk of diabetes
raises the risk of heart attacks
triggers autoimmune disease

Truth-bombs about how the pill works

She shares plenty of truth-bombs about how the pill works – like these gems:

As long as you’re on the pill, your brain and ovaries aren’t talking, which can seriously affect all your hormones.

When you take that week of placebo pills, you’re not actually getting a period because you never ovulated. Instead, this is what is called a withdrawal bleed (I did not know this!)

Post–birth control syndrome (PBCS)

I first became aware of Dr. Jolene’s brilliance in this area when she started writing about Post–birth control syndrome (PBCS) a few years ago. PBCS is “is a constellation of symptoms women experience when they discontinue hormonal birth control.” She has found the symptoms of PBCS – hormonal irregularities like no period or heavy bleeding, acne, mood swings and anxiety, headaches, infertility, pill-induced PCOS (polycystic ovarian syndrome), hypothyroidism, gut issues and even autoimmune symptoms – typically occur in the first 4-6 months after stopping the pill. To make it easy for you the PBCS symptoms are all laid out in a handy quiz in the book.

She has found these symptoms won’t go away without taking the necessary steps that include detox, gut repair, healing the thyroid and adrenals, addressing metabolic health or blood sugar control, boosting mood, improving libido and addressing nutritional deficiencies that the pill has caused. This is all covered in the book as a 30-day program to balance your hormones, reclaim your body, and reverse the dangerous side effects of the birth control pill.

I really appreciate that Dr. Jolene shares this:

I want you to know I’m not anti-pill. Nope. I’m pro–informed consent, which means doctors giving you all the information you need to consent to taking birth control.

This book will help you understand what those hormonal symptoms mean, how the pill is affecting your body, and what to do if you either need to stay on it or are ready to get off it.

Addressing low vitamin B6, low serotonin and low GABA

Here are a few of the nutritional supporting approaches she covers (all supported by research) that are very applicable for support for anxiety specifically and relevant to what you’ve been learning from me: addressing low vitamin B6, low serotonin and low GABA.

Because the pill depletes vitamin B6, she recommends up to 100mg per day for PMS and mood-related symptoms, and symptoms of PBCS. (I know vitamin B6 is controversial and she does acknowledge this).

Dr Jolene identifies the concerning and far-reaching effects of the pill on serotonin: “studies have shown that women on the pill don’t metabolize tryptophan normally” affecting both serotonin and melatonin production, reducing kynurenic acid and raising high-sensitivity C-reactive protein (hs-CRP), a marker of inflammation and immune system activation, and shifting the “tryptophan pathway… toward quinolinic acid production, which is inflammatory and harmful to the brain.”

I would have loved to see more about tryptophan and 5-HTP and even vitamin B6 (given that it is crucial for the conversion of tryptophan away from quinolinic acid) in this section of the book. Using tryptophan as a supplement is only briefly mentioned and 50-100mg 5-HTP is only recommended for serotonin-related cravings. As you may know from my work using targeted trials of the amino acid tryptophan and/or 5-HTP offers very quick anxiety relief and support for PMS within 3 cycles. Fortunately, you can fill in the gaps and use what I teach about these amino acids in conjunction with everything else in the book.

I do love that she adds to our knowledge base with other tips, sharing that the botanicals “passionflower and skullcap support healthy serotonin production by reducing quinolinic acid production.” This was new to me and I’m intrigued.

I love what she writes about progesterone inducing “a sense of calm and a deep sense of love and connection by stimulating gamma-aminobutyric acid (GABA) receptors.” Theanine and taurine (a precursor of GABA) are recommended and taurine is also part of her detox and adrenal protocols which I love.

However, I use GABA itself extensively in my work and find it to be more effective than theanine or taurine for the anxiety symptoms – it’s a firm favorite for the majority of my anxious clients. Again, you can fill in the gaps and check out what I share about GABA for very quick anxiety relief and PMS support.

My other favorite sections: libido and orgasms, and liver detox

Some of my other favorite sections include the libido section and her wonderful information about orgasms – she shares the myriad of health benefits of orgasms and recommends once-weekly orgasms but need I say more than this comment from Dr. Jolene:

Women can have four different types of orgasm throughout the month because of the hormonal changes we experience. Dude, this is a serious reason to consider ending that pill pack.

I couldn’t resist including this advice for anxiety and insomnia:

Trouble with anxiety? Have sex. Trouble with insomnia? Have sex. When you have an orgasm and release oxytocin, it relaxes you, calms your mind, and enables you to get a good night’s sleep. Besides oxytocin, your body releases vasopressin during orgasm, a hormone that often accompanies the release of melatonin.

If you do have low libido Dr. Jolene has this covered.

I also love the liver detox chapter and so will you. You’ll learn that the pill can cause benign liver tumors and can contribute to gallstones and gallbladder disease. She also shares this about the synthetic estrogen in birth control pills and the liver/libido connection:

There is some concern that long-term exposure to the synthetic estrogen in birth control pills actually alters your liver genes to make higher levels of SHBG (sex hormone binding globulin) for the rest of your life. Unfortunately, SHBG also binds up your testosterone. The result is a libido that’s nonexistent.

She also has you covered on how to detox as part of this wonderfully comprehensive hormone balancing program.

The official book blurb

Out of the 100 million women – almost 11 million in the United States alone – who are on the pill, roughly 60 percent take it for non-contraceptive reasons like painful periods, endometriosis, PCOS, and acne. While the birth control pill is widely prescribed as a quick-fix solution to a variety of women’s health conditions, taking it can also result in other more serious and dangerous health consequences.

Did you know that women on the pill are more likely to be prescribed an antidepressant? That they are at significantly increased risk for autoimmune disease, heart attack, thyroid and adrenal disorders, and even breast and cervical cancer? That the pill can even cause vaginal dryness, unexplained hair loss, flagging libido, extreme fatigue, and chronic infection.

As if women didn’t have enough to worry about, that little pill we’re taking to manage our symptoms is only making things worse.

This book is perfect for you if

You’re a woman in your child-bearing years and are currently on the pill, considering the pill, have been on the pill in the past and had issues, and even did well on the pill in the past
You’re a woman like me and past the birth control age and yet are intrigued to get a better understanding of how you may have been affected by the pill in the past and also want a better understanding of your body and hormonal health going forward
You have a daughter or grand-daughter or niece or friend you can gift a copy to
You are a practitioner who works with women
You are a curious male with women in your life and would like to understand them better so you can continue to have the healthiest relationship possible.

I’m already recommending this book and will continue to recommend it going forward!

This much-needed solution-based and heavily referenced book released January 29. It’s ground-breaking information and I’m thrilled to be sharing it with you!

Grab your copy of Beyond the Pill (my Amazon link) and find additional information here.

I now recognize that post–birth control syndrome (PBCS) was part the perfect storm that contributed to my anxiety and panic attacks in my late 30s (and a whole host of other symptoms). Personally, I found the entire book fascinating reading, and wish I’d had access to this material while I was in the midst of trying to figure things out.

Fortunately, GABA and tryptophan helped immensely with my anxiety and PMS (together with everything else I did) and I eventually discovered FAM (Fertility Awareness Method). But wish I’d know about this safer option when I was younger. Dr. Jolene is a big fan of FAM and covers it extensively in the book, sharing what I found to be true: it works even if it seems scary at first AND you get to learn so much about your body.

Please feel free to share your experiences with the birth control pill (both good and bad), why it was prescribed and what you learn from this book that can help others in your situation. Feel free to post questions here too.