GABA

Theanine for easing stress and anxiety, and improving cognition and sleep in healthy adults

January 24, 2020 By Trudy Scott 14 Comments

L-Theanine is a “unique non-protein amino acid found in green tea” which according to the study below, has shown benefits when used short-term or acutely as a supplement for it’s anti-stress effects, reducing anxiety, improving sleep quality, improving cognition and even easing depression.

This 2019 study, Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial, aimed to examine the effects of four weeks use of l-theanine:

on stress-related symptoms and cognitive functions in healthy adults. Participants were 30 individuals (nine men and 21 women; aged 20-69) who had no major psychiatric illness.

The trial was randomized, placebo-controlled, crossover, and double-blind.

L-theanine (200 mg/day of Suntheanine), was used by study participants before going to bed each night and was used for four-weeks.

Study participants who used the theanine for two weeks observed the following:

For sleep: Reductions in sleep latency (the amount of time it takes to fall asleep), sleep disturbance and less use of sleep medication
For cognitive function: Improvements in verbal fluency (especially letter fluency) and improvements in executive function (planning, multi-tasking etc)

The Japanese versions of The Self-rating Depression Scale, State-Trait Anxiety Inventory-trait, and Pittsburgh Sleep Quality Index (PSQI) scores decreased and the study concludes as follows:

Our findings suggest that L-theanine has the potential to promote mental health in the general population with stress-related ailments and cognitive impairments.

The authors also note that “there were no significant adverse events, demonstrating the safety of four weeks of L-theanine administration.”

As expected, the participants saw increases in serum theanine concentrations. What is unusual and inconsistent with previous studies, is the fact that there was “no significant effect on cortisol or immunoglobulin A levels in the saliva or serum.” I’m not sure I understand the reasoning they propose i.e. that “the reduction of salivary cortisol and immunoglobulin A levels may be short term, recoverable effect of L-theanine administration.” I’ll be digging deeper into this to try and get a better understanding of these differences.

Some of the reported possible mechanisms of action

Here are some of the reported possible mechanisms of action of theanine from some studies referenced in his paper:

via glutamate receptors (improving cognitive dysfunction)
as a neuroprotective agent and “increases in brain serotonin, dopamine, GABA levels” (improving mood and focus and reducing anxiety)
enhances hippocampal activity (the hippocampus has a major role in learning and memory)
via a proposed increase in the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus (BDNF is a protein implicated in the stress response, long-term memory, Alzheimer’s disease, and psychiatric disorders)

Theanine or GABA – which one to use when?

I typically start my clients with a trial of GABA Calm for low GABA symptoms like physical tension, stress and overwhelm, panic attacks and insomnia. If we are not getting all the expected benefits with GABA and there is a need for added cognitive benefits then we’ll consider adding theanine too. Some folks find one works better than the other and some like a combination (at the same time or theanine in the day/GABA at night or GABA in the day/theanine at night).

I recently reached out on facebook asking: “Theanine or GABA? Which do you prefer for anxiety and why? How much helps? And any other benefits (like reduced body pain, better thinking/cognition, easing IBS gut pain, reduced cravings, less negative self-talk etc)?Or do you like a combination of both?”

As you can see from these varied responses it’s a matter or trialing both to find what works for each person’s unique needs:

Lorraine shared this: “They are both good, but I reach for GABA Calm first.. 2 or 3 lozenges. If anxiety doesn’t leave quickly with GABA ( which works well for a panic attack), and I continue to have anxiety humming along in the background, then I’ll reach for theanine.”
Jackie shared this: “I take 200mg theanine in morning, then 100mg GABA around 4pm, when the kids get home from school. I had a panic attack in the middle of the night last week, took GABA 100 mg, then seemed to calm down.” I asked if theanine gives her a feeling of calm focus and she said: “yes, I think so. I noticed if I take 200mg of GABA, it makes me drowsy.”
Evelyn shared this: “I use both at night for sleep. If I could only use one it would be l-theanine.” Theanine is more consistently helpful for stress reduction and sleep for me. I use 200mg. When I use GABA it’s 500mg of chewables.”
Sara shared this: “GABA during the day, theanine at night.”
Karine shared this: “GABA!! The Source Naturals Theanine Serene with Holy Basil is really good. But GABA Calm (also Source Naturals which is a sublingual lozenge) is the only thing for a severe issue/episode and helps me concentrate right before an important presentation at work etc. Pure GABA from any supplier is good for long periods where you need a boost or to tone down general anxiety. I also bought a probiotic that also includes GABA (Jarrodophilus Mood) and notice it improves digestion too.”

You can find my favorite GABA/theanine combination product, a theanine-only product and my most popular GABA products on the supplements blog here (and with details for how to set up an account for my online store)

Nutritional Fundamentals for Health GABA-T SAP: 300mg GABA, 150mg theanine. This is pleasant-tasting when opened on to the tongue and works very well when GABA Calm can’t be used.

Pure Encapsulations L-Theanine: 200mg theanine. This is also pleasant-tasting when opened on to the tongue. Unlike like GABA, it can also be swallowed.

Source Naturals GABA Calm. This is a pleasant-tasting sublingual product that is my most popular and most effective form of GABA I use with my clients. It can be used in conjunction with theanine.

Enzymatic Therapy GABA: 250 mg GABA. This is also pleasant-tasting when opened on to the tongue and works very well when GABA Calm can’t be used. It can also be used in conjunction with theanine.

Please let us know … theanine or GABA: which do you prefer for anxiety and why? How much helps? And any other benefits (like reduced body pain, better thinking/cognition, easing IBS gut pain, reduced cravings, less negative self-talk etc)? Or do you like a combination of both?”

Essential tremor, dystonia, anxiety and cravings – diet, GABA, tryptophan, zinc and vitamin B6

January 17, 2020 By Trudy Scott 34 Comments

Today I’m sharing how diet, GABA, tryptophan, zinc, vitamin B6 and other B vitamins can resolve essential tremor and sugar cravings in 2 months, and also resolve musician’s dystonia and social anxiety within 4 months.

According to Medical News Today essential tremor is a movement disorder that can cause hand tremors and “is among the most common movement disorders.” … “The tremor usually affects both sides of the body, but it may be more noticeable in the dominant hand. It tends to occur when the person is moving as well as when standing still. Genetics may be responsible for around half of the cases of essential tremor.”

Essential tremor – diet, GABA, tryptophan and B vitamins

This Croatian paper, Treatment of Essential Tremor with Multi-Modal Nutritional Therapy in a Teenage Patient, reports the “case of a 13-year-old boy with [essential tremor] causing severe functional impairment” over the previous 2 years.

“A multi-modal nutritional therapy approach” was used to target three possible areas that could be contributing to the tremors: a poor diet that was high in sugar, low GABA levels and low serotonin. These changes were implemented:

(i) diet (specifically adopting a Mediterranean diet)

(ii) GABA (through oral supplementation) and

(iii) L-tryptophan/vitamin B pathways (Triptobel oral supplement).

The papers states: “After two months of therapy, his tremor decreased significantly and he regained normal function.”

Once the essential tremor resolved, this teen was able to resume his plans to pursue a musical career as a guitar player (which had been put on hold due to the tremor and his inability to play). What wonderful results!

I’m thrilled to see tryptophan and GABA being used for this condition and am really pleased to read this case report. Here is my commentary on the supplements and doses he used for anyone wishing to try and replicate this nutritional approach (keeping in mind there is no one-size-fits-all).

He used 150 mg of the Triptobel supplement three times daily at 8 am, 1 pm, and 6 pm. One capsule of the Triptobel contains 150mg L-tryptophan and a B vitamin complex of thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), vitamin B6, folic acid (vitamin B9), and cyanocobalamin (vitamin B12). The total tryptophan dose was 450mg per day. A typical starting dose for someone with anxiety is 500mg 2 x day so his dose was on the low-end. The Triptobel was also used at mealtimes and according to the label “on a full stomach after a light meal, preferably without protein.” I like to use tryptophan between meals (away from protein) and a B complex with meals so I’m intrigued by this application (but wonder when protein was consumed).
He also used 750mg GABA twice daily at 10 am and 4 pm. This is considered a high starting dose for the majority of my clients with anxiety and I start low and build up to this amount.

Anxiety and low mood was not mentioned so I don’t know if they were factors.

It appears sugar and carb cravings were very likely a factor given that his normal daily diet contained “large amounts of refined sugars (chocolate, cake, biscuits, ice cream, etc).” The amino acids would have helped him with those cravings.

With regards to his diet, given how common movement disorders are with gluten issues, I would also consider I gluten-free diet which has been shown to have an adverse impact on neurotransmitter levels and B vitamins. Could gluten have triggered these nutritional deficiencies and the tremors?

And now to share a very similar case in an adult male … with a different and yet related approach.

Dystonia and hand tremors – and the pyroluria connection

This same Medical News Today article also describes dystonic tremor/dystonia as a movement disorder that can also cause hand tremors, stating that “the brain sends incorrect messages, resulting in overactive muscles, abnormal postures, and sustained undesired movements. Young adults and those in middle age are most likely to develop dystonic tremors, which can occur in any muscle.”

If you’ve been reading my recent articles on pyroluria (the pyroluria-vagus nerve connection and the introversion-pyroluria-loneliness connection) I’m sure you’ll be be interested to learn that there appears to be a strong link between pyroluria and focal musician’s dystonia (or musician’s cramp) in some individuals.

As you read in the blog above, Jay, also a guitar player, had to put his professional music career on hold due to musician’s dystonia. He also happened to have social anxiety and he started to notice improvements in his anxiety and tremors within the first 2 weeks. At the end of 4 months of being on the pyroluria protocol, he shared this:

I think it is, at this point, safe to say that the pyroluria treatment [120mg vitamin B6 and 60mg zinc) is, at least in my case, the cure for pyroluria and dystonia. 90%+ of my symptoms have disappeared, I am working extensively on repertoire and I am thinking about getting back into performing.

He says his experience was “akin to rebirth as a musician and also as a person.” How wonderful is that to read. Jay’s musician’s dystonia resolved and so did his social anxiety.

The outcome for the teen and Jay were similar and yet the approaches used were seemingly very different. This isn’t actually the case since zinc and vitamin B6 are co-factors that are needed to make GABA and serotonin.

Do you experience tremors, or have you been diagnosed with essential tremor or dystonia (or know someone who has)? And have you considered a nutritional approach?

Do share if you’ve seen success with either of the above approaches, and also experienced reduced anxiety or felt more social?

Parasites, Anxiety and TUDCA for Your Liver with Dr. Jay Davidson: The Anxiety Summit 5

November 22, 2019 By Trudy Scott 1 Comment

***** IT’S ENCORE WEEKEND OF THE ANXIETY SUMMIT – NOV 23-24 ******

Dr. Jay Davidson is one my guest experts on The Anxiety Summit 5: Gut-Brain Axis and our topic is: Parasites, Anxiety and TUDCA for Your Liver. What you’ll learn

Parasite facts and myths
New dosing options for mimosa pudica seed
TUDCA for liver, neuroinflammation and depression

and much more. It’s an excellent interview and was voted as one of the top 5 interviews of the summit.

After hearing Dr. Jay’s explanation of what a parasite is, I couldn’t resist using the above image of a happy worm. This is what he shares:

the Greek meaning of parasite is one that sits at another’s table. So essentially think of a parasite as it’s taking things from you. It’s taking nutrients, it’s taking key things that your body needs and literally off of you, not to the point that it’s killing you because then you’re not a good host to give a good environment. So it’s basically just kind of sucking you dry.

Unfortunately you have this very “happy” and satisfied parasite sitting at your “table” and causing all kinds of symptoms:

Mood stuff for sure, which obviously this is The Anxiety Summit. So we want to highlight that one, absolutely. Sleep issues though. In the big sleep one that I see is restless sleep where you toss, you turn, you wake often. You can’t just be relaxed when you sleep. Parasites get active when you go to bed.

So the more active they are within your body and the more you’re trying to calm down, the more your body is getting stressed out. This is where teeth grinding happens when you sleep. This is, again, where the restless legs. You can also say the calf cramping, restless leg type symptoms would come in as well being associated. It’s classic, though, for parasites to affect the gut. So obviously diarrhea, is clearly a classic sign of acute parasitic type infection.

Other symptoms we discuss at length: bowel urgency, SIBO, vertical wrinkles above your mouth, nail-biting, food sensitivities, bed-wetting, insomnia (especially around full moon), grinding teeth, night sweats and anxiety, and also how parasites affects neurotransmitter imbalances.

We cover why and how do do the parasite protocol before, during and after the full moon, his parasite story and the latest information on mimosa pudica seed:

So mimosa pudica seed is an amazing, just overall gut support. So even if your goal isn’t the parasite cleanse, mimosa pudica seed is awesome to help support the digestive tract. It can help break up biofilm. It’s really good against Candida and just helping to normalize microbial levels within the GI besides the fact that it can help with parasites.

Dr. Jay shares what he’s seeing clinically in terms of dosing mimosa pudica seed and when exactly to use it.

I share that I found an animal study where they were looking at the whole plant extract and found that it helped with modulating GABA receptors. And they said it had very similar effects to diazepam, which is a benzodiazepine that a lot of people with anxiety are prescribed. Fascinating!

The latter half of the interview focuses on drainage and supporting bile production with TUDCA, which also happens to support the mitochondria and help prevent Alzheimer’s disease.

I encourage you to also listen to Pyroluria, Oxidative Stress and Parasites with Todd Watts, DC, PScD. We discuss some of these same protocols in the context of pyroluria/social anxiety and oxidative stress.

You’re going to be hearing a lot more from me about these products and protocols as I learn more and trial them personally.

You may notice this image doesn’t look like the video on the summit. This was one of 4 interviews we had to repeat due to technical issues!

Be sure to listen to Dr. Jay’s wonderful interview on The Anxiety Summit 5: Gut-Brain Axis. As I mentioned, his interview was voted as one of the top 5 interviews of the summit. The other 4 top voted interviews are:

Fix the Brain to Fix the Gut – Datis Kharrazian, DHSc, DC, MS, FACN, CNS (more here)
Why Bile is the Key to Anxiety & Hormone Havoc – Ann Louise Gittleman, PhD, CNS (more here)
Vagus Nerve Activation to Reduce Anxiety – Dr. Navaz Habib, DC (more here)

and my interview GABA & Tryptophan: The Gut-Anxiety Connections (more here)

If you have already signed up for the summit and have been tuning in, I do hope you enjoy these interview highlights and the encore weekend. Look out for encore weekend emails from Health Talks Online.

If you have yet to sign up, please do come and join us and learn on this encore weekend – November 23-24 – when all the interviews will be replaying for 48 hours.

Encore weekend

If you’re considering purchasing the summit to keep for your learning library, you have a number of options that include:

Online only or flash drive or both
A PDF or printed transcripts of all the interviews
The Best of Anxiety-Gut interviews from previous Anxiety Summits
GABA Quickstart Program (a group program with me on how to actually use GABA for your physical anxiety, with a private Facebook group and live Q & A call)

Purchase options

If you’re already familiar with Dr. Jay’s parasite protocols and TUDCA please share how they have helped you. That way we can all learn.

If you’d like to ask a question, please post in the comments below.

I’d also love to hear from you once you’ve listened in to Dr. Jay’s interview and the others.

Sage, gluten, CBD and gut-brain axis: highlights from The Anxiety Summit 5

November 8, 2019 By Trudy Scott 13 Comments

Today I’m sharing a few highlights from The Anxiety Summit 5: Gut-Brain Axis which airs November 11-17. We cover all new material, it’s research-based and we talk about practical solutions.

The highlights cover sage and other herbs that can impact GABA and anxiety; new testing for gluten issues; CBD and the role in gut health, anxiety and PTSD; and the microbiome and gut-brain axis and neurotransmitters.

#1 Herbs to Improve Digestion and Support GABA ~ Magdalena Wszelaki, author of Cooking for Hormone Balance, shares this in our interview

Astringents like sage, rose and red raspberry tighten loose junctions in IBS, support female hormonal health and ease anxiety.

We discuss sage and make reference to this study called Flavonoids: some of the wisdom of sage? which concludes that the “actions of molecules such as hispidulin [a flavonoid found in sage] might be able to target GABA_A receptors for the management of anxiety and epilepsy.”

What I really love about this interview is that Magdalena brings it all back to practical steps and shares how to make a healing medicinal tea.

#2 Latest Gluten Research and Testing (Part 2) ~ Dr. Tom O’Bryan, DC, CCN. We discuss the Neural and Wheat Zoomer tests and Dr. Tom shares this:

Let’s do a different test that’s more accurate and more sensitive. That’s why the Wheat Zoomer looks at 26 different peptides of poorly digested wheat. And it’s the most comprehensive test on the market today …. on the Anxiety Summit, the ones that you’d be most concerned about is the gluteomorphins and the prodynorphins because those antibodies attack the opiate receptors, and that is critically important with brain dysfunction.

#3 Gut-Brain Axis and Mental Health ~ Peter Bongiornio, ND, LAc, author of Put Anxiety Behind You, talks about the microbiome and bidirectional aspects:

so we have this microbiota, all these germs and bacteria that are in our digestive tract as an example. What we’re seeing now is that the health and the diversity of those create either a healthy brain or an unhealthy brain; that the microbiota that are in our gut actually play a very, very strong role and how neurotransmitters are made both in the gut and in the brain. As well as they also create inflammatory molecules and peptides and things that also travel to the brain and will affect brain inflammation, and affect brain neurotransmitters and affect the receptors of these neurotransmitters as well.

#4 Endocannabinoid System and Your Gut ~ Hyla Cass, MD, talks about CBD and anandamide in the endocannabinoid system:

CBD influences the breakdown of anandamide , extending it’s use. Anandamide is found in both the brain and the gut and the name comes from the Sanskrit word ananda, which means bliss.

So what CBD is doing is extending the life of the anandamides, so they can act longer. Dr. Cass also shares the connection between the endocannabinoid system, stress, the HPA axis, the gut and PTSD:

we react to stress and trauma through the hypothalamic pituitary-adrenal axis/ the HPA Axis. And the endocannabinoid system tends to tone down or modulate the HPA axis to protect us from stress. And when it’s protecting us from stress in that way, it’s also signaling to the GI system to calm down. People that don’t have enough endocannabinoid activity are more likely to have posttraumatic stress disorder.

The Anxiety Summit 5: Gut-Brain Axis airs online Monday Nov 11 to Sunday Nov 17, with replays the following weekend. I do hope you’ll be joining us.

If you’re having any doubts, read this delightful message I received this week and be inspired and motivated to tune in and learn:

Trudy … thanks so very much for the 3 transcripts featuring Ann Louise Gittleman, Carolyn Ledowsky and Dr. Datis Kharrazian … they were ALL fantastic and unlike many of the health related docu-series, I felt that I obtained some great insights and key take-aways that will help me on my road to good health journey! You asked some GREAT questions and I appreciate you digging further for names of supplements and more specificity to ensure clarity. You are a PRO and I am so glad I found you ❤️

Please join us and listen to this interview and all the others on The Anxiety Summit 5: Gut-Brain Axis.

When you register now you’ll get access to there 3 interviews right away:

Fix the Brain to Fix the Gut – Datis Kharrazian, DHSc, DC, MS, FACN, CNS
MTHFR, B12 Genes and Anxiety – Carolyn Ledowsky, ND
Why Bile is the Key to Anxiety & Hormone Havoc – Ann Louise Gittleman, PhD, CNS

If you have already signed up for the summit, I hope you enjoy these interview highlights.

If you have yet to sign up, please do come and join us and learn.

If you’re considering purchasing the summit to keep for your learning library, you have a number of options that include:

Online only or flash drive or both
A PDF or printed transcripts of all the interviews
The Best of Anxiety-Gut interviews from previous Anxiety Summits
GABA Quickstart Program (a group program with me on how to actually use GABA for your physical anxiety, with a private Facebook group and live Q & A call)

Purchase options

If you have already purchased, I know you’re going to find immense value from this material to be able to refer back to again and again.

What gems stand out for you today and do you have questions?

If you’d like to ask a question, please post in the comments below.

I’d also love to hear from you once you’ve listened in to these interviews and the others.

Vagus Nerve Activation to Reduce Anxiety with Dr. Navaz Habib: The Anxiety Summit 5

November 1, 2019 By Trudy Scott 2 Comments

Navaz Habib, DC, is one my guest experts on The Anxiety Summit 5: Gut-Brain Axis and our topic is: Vagus Nerve Activation to Reduce Anxiety. What You’ll Learn –

Using bowel transit time and heart rate variability to measure how your vagus nerve is working
How the vagus nerve becomes dysfunctional
Vagus nerve activation tools: gargling, auricular acupuncture, social interaction
and more

Dr. Navaz shares this about the vagus nerve and why good vagus nerve function is so important for both good digestion and for easing anxiety (and preventing it too):

the vagus nerve is one of many cranial nerves. So we have 12 pairs of cranial nerves, or nerves that begin within the head cavity, and they exit to the brainstem at that point.

The vagus nerve is the 10th pair of cranial nerves. So it’s called the 10th cranial nerve, as well. And there’s one on each side. There’s actually one on the left and one on the right. So it is a pair and is the vagus nerves in reality. But the vagus nerve is the only cranial nerve of those 12 pairs that will exit the cranium. Okay. So it does have some function in and around the face and the throat, but it does exit and go into other areas of the body.

And that’s what makes the vagus nerve so important. It is the only one that does so. And it goes to innervate so many different organs inside our body. This includes the heart, the lungs, stomach, gallbladder, liver, kidneys, every single part of our digestive tract, as well as our spleen. So all of these organs need to have a certain level of information that’s passed from the brain to those organs, but we also need all of those organs, especially the gut, to send that information back up to the brain. And the vagus nerve is very, very important in that specific function.

He shares the two tests he uses to ensure his clients have strong vagus nerve function:

the bowel transit time test: “how much time is it is actually going to take for the food that we ingest from our mouth to exit through the opposite end, to go through the entire digestive tract and leave”
heart rate variability test which measures vagus nerve function directly: “heart rate variability is actually the measurement of the amount of time in milliseconds between beats of the heart.”

We go into great detail on each of the above tools and how to use them and we also discuss some of the research. This paper is fascinating: Vagus Nerve as Modulator of the Brain-Gut Axis in Psychiatric and Inflammatory Disorders. Here are some highlights from our discussion:

how inflammatory disorders and psychiatric disorders are so interconnected through the vagus nerve function
gut-brain axis sends information/chemicals from gut bacteria, parasites, viruses, yeast etc. up through the vagus nerve to the brain.
it involves the inflammatory system or the cholinergic anti-inflammatory system and acetylcholine
if we have gut dysfunction that can lead to dysfunctional inflammatory control, immune dysfunction and autoimmune diseases
it’s going to lead to inflammation in the brain, and in the entire nervous system and that’s where a lot of mood disorders like anxiety and depression really start to come from because we now know that serotonin, dopamine, norepinephrine, and epinephrine levels are highest in the gut.
this can lead to depressive type symptoms, mood type symptoms, and significant fear and worry that we find in anxiety.

When I found out that Dr. Navaz had written a book called “Activate Your Vagus Nerve: Unleash Your Body’s Natural Ability to Heal” (my Amazon link), I reached out to him to speak on the summit, and I’m so glad I did. I know you’ll love this interview as much as I do and will get tons out of it!

We cover how vagus nerve function can be impacted – lack of sleep and hormonal imbalances can be factors. A big trigger is trauma and I share my traumatic plane ride and how it affected my vagus nerve, voice and throat. I blogged about this and if you missed all that be sure to check the blog and videos in advance of our interview: Vagus nerve rehab with GABA, breathing, humming, gargling and key nutrients. The amino acid GABA was central in relaxing the throat spasms I experienced.

And we end with very practical ways to activate your vagus nerve

Deep breathing exercises and cold showers (“cold showers are a really great way to make our breathing a little bit more difficult. It’s like adding a weight onto the breath/onto the chest so that we’re forcing ourselves to breathe as well as we possibly can even under stressful circumstances”)
Gargling and using the gag reflex
Humming, chanting and singing (I used these approaches for my vagus nerve issue)
Auricular acupuncture (which is also very effective for addictions)
And finally, social interaction (I love this one and we talk about pyroluria and why addressing this social anxiety condition with nutrients is also so important for vagus nerve

Be sure to listen to Dr Navaz’s wonderful interview to get a complete picture of the importance of the vagus nerve, how it can start to function poorly and how to reactivate it to improve gut health and help with anxiety and mood issues.

It will lay a great foundation for the mentions of vagus nerve in many of the other interviews.

Please join us and listen to this interview and all the others on The Anxiety Summit 5: Gut-Brain Axis.

When you register now you’ll get access to there 3 interviews right away:

Fix the Brain to Fix the Gut – Datis Kharrazian, DHSc, DC, MS, FACN, CNS
MTHFR, B12 Genes and Anxiety – Carolyn Ledowsky, ND
Why Bile is the Key to Anxiety & Hormone Havoc – Ann Louise Gittleman, PhD, CNS

If you have already signed up for the summit, I hope you enjoy these interview highlights.

If you have yet to sign up, please do come and join us and learn.

If you’re considering purchasing the summit to keep for your learning library, you have a number of options that include:

Online only or flash drive or both
A PDF or printed transcripts of all the interviews
The Best of Anxiety-Gut interviews from previous Anxiety Summits
GABA Quickstart Program (a group program with me on how to actually use GABA for your physical anxiety, with a private Facebook group and live Q & A call)

Purchase options

If you’re already familiar with the importance of the vagus nerve and already do work on activation (to improve gut health and help with anxiety) please share what you find works for you. That way we can all learn.

If you’d like to ask a question, please post in the comments below.

I’d also love to hear from you once you’ve listened in to Dr. Navaz’s interview and the others.

GABA & Tryptophan: The Gut-Anxiety Connections with Trudy Scott on The Anxiety Summit 5

October 14, 2019 By Trudy Scott 12 Comments

One of my three interviews on The Anxiety Summit 5: Gut-Brain Axis airs on day 1 of the summit. The topic is: GABA & Tryptophan: The Gut-Anxiety Connections. In this interview, I’m interviewed by my colleague and friend Dr. Nicole Beurkens, PhD, and you’ll learn about:

Low serotonin: fear, overwhelm, gut motility & anorexia
Low GABA: physical tension, gut & rectal pain, burning mouth
Blood brain barrier, phenibut, candida & CBD

I start with some background on why a summit on the gut-brain axis, what we don’t know about the incidence of anxiety and the huge increase we are seeing. The big message is that we have growing awareness but no real solutions. This goal of this summit is to create awareness around gut issues as a possible root cause and the growing research in nutritional psychiatry – AND to provide solutions!

We cover some of the basics in case you don’t know anything about GABA and tryptophan. If you’ve been following my work you’re likely going to be familiar with this section.

I cover plenty of new research throughout the interview and we start with 5-HTP as it relates to both gut health and anxiety. We discuss this 2019 paper: Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression:

Administration of 5-HTP SR [slow release] to mice restored [serotonin] to the ENS [enteric nervous system] and normalized GI motility and growth of the enteric epithelium.
5-HTP SR [slow release] might be used to treat patients with intestinal dysfunction associated with low levels of 5-HT [serotonin].

This paper doesn’t mention anxiety or depression but we know that serotonin support with 5-HTP or tryptophan addressed this aspect too. And given this, it’s very possible that we could extrapolate some of this research to tryptophan.

We cover motility issues at length in the SIBO (small intestinal bacterial overgrowth) interviews with Dr. Alison Siebecker and Shivan Sarna – SIBO: Anxiety, Testing, Probiotics and Fecal Transplants (Part 1 and 2). We also talk about the fear and overwhelm factor when starting a new protocol in that interview and in this interview of mine – and how addressing low serotonin helps so much.

We also talk about one of my favorite topics: GABA and the controversial blood-brain-barrier question and point you back to the discussion I have with Dr. Datis Kharrazian in his interview: Fix the Brain to Fix the Gut. Be sure to tune in to that one.

I also share some research on low serotonin and gut health in anorexia; interesting anti-candida properties of serotonin; how CBD can make tryptophan more effective (be sure to tune in to Dr. Hyla Cass’ interview for more on this: Endocannabinoid System and Your Gut); new GABA studies; the phenibut FDA ban; and updates on some possible reasons why one or more of the amino acids don’t work as well as expected when you do the questionnaire, you have all the symptoms, you review the precautions and a do a trial.

I mentioned this is one of 3 interviews I do on the summit. My other 2 interviews cover:

How Collagen Can Cause Anxiety and Insomnia
Simple Solutions for Anxiety and Gut Health

I’ll share highlights from these ones in another email/blog.

Please join us and listen to my interviews and all the others on The Anxiety Summit 5: Gut-Brain Axis.

When you register now you’ll get access to there 3 interviews right away:

Fix the Brain to Fix the Gut – Datis Kharrazian, DHSc, DC, MS, FACN, CNS
MTHFR, B12 Genes and Anxiety – Carolyn Ledowsky, ND
Why Bile is the Key to Anxiety & Hormone Havoc – Ann Louise Gittleman, PhD, CNS

If you have already signed up for the summit, I hope you enjoy these interview highlights.

If you have yet to sign up, please do come and join us and learn.

If you’re considering purchasing the summit to keep for your learning library, you have a number of options that include:

Online only or flash drive or both
A PDF or printed transcripts of all the interviews
The Best of Anxiety-Gut interviews from previous Anxiety Summits
GABA Quickstart Program (a group program with me on how to actually use GABA for your physical anxiety, with a private Facebook group and live Q & A call)

Purchase options

If you’d like to give feedback or ask a question, please post in the comments section at the bottom.

I’d love to hear from you once you’ve listened in to this interview and the others.