Women's health

How GABA eases agonizing rectal pain and spasms in under 2 minutes

June 30, 2017 By Trudy Scott 62 Comments

Proctalgia fugax is described as a condition that leads to rectal spasms and sharp fleeting pain in the lower rectum or anus. In some people it can be more than fleeting and is often described as excruciating and agonizing.

This paper describing proctalgia fugax shares how this pain can

recur over weeks, is localized to the anus or lower rectum, and can last from seconds to several minutes with no pain between episodes. There is no diurnal variation. There are numerous precipitants [preceding factors] including sexual activity, stress, constipation, defecation and menstruation, although the condition can occur without a trigger.

Although the cause of proctalgia fugax is unclear, spasm of the anal sphincter is commonly implicated. The condition may be more likely to occur after sclerotherapy for hemorrhoids and vaginal hysterectomy. There are also associations with other functional pathologies, such as irritable bowel syndrome and anxiety.

My story

I have experienced this awful anal sphincter spasm and pain myself so I want to shine some light on this condition and offer the simplest and most effective solution: oral and sublingual GABA. It works to completely eliminate the pain in 1-2 minutes! And it can also be used to prevent a full-on spasm if you catch it in advance. More about this below.

Let me first share my story so you can relate to the pain. I started to experience this a few years ago. It was right after my aunt died from rectal cancer and my immediate thought was that I was dying of cancer. That’s how bad the pain was. It’s like nothing I’ve ever experienced and I’ve had some pretty bad pain experiences: shingles, a tick bite headache, ice-pick headaches from a neck injury and poking my eye on a tree-branch while hiking.

For me, since it initially used to happen during the night, it felt like I was in bad dream and was lying somewhere injured and in agony. I would half wake-up moaning in pain, not quite grasping how the pain I was feeling could be so bad. Then I would come fully awake and feel the need to bear down (as in needing to have a bowel movement) but this would actually make it worse.

How do others describe the pain?

When I shared this paper on facebook one woman said her rectal pain and spasms last 20-30 minutes and is bad a childbirth.

Someone else shared that her husband “complained of feeling like a knitting needle was being driven through his anus.”

What do I think my triggers are?

I have not had sclerotherapy for hemorrhoids or a vaginal hysterectomy. I do have a history of anxiety and panic attacks (in my late 30s) and do have IBS/SIBO right now and I suspect that both low GABA and IBS/SIBO are my biggest root causes. I no longer have any anxiety but since I respond so well to GABA I assume my GABA levels are not optimal (likely due to the SIBO). I suspect exposure to hidden sources of gluten could also be a factor, and this could also affect my GABA levels.

Medications or heating pads as a solution?

I didn’t ever consider the conventional approaches which include: botox, benzodiazepines, SSRIs, Gabapentin, lidocaine, oral diltiazem, topical glyceryl nitrate, nerve blocks or salbutamol.

A warm bath has been reported to help but I was looking for a 1-2 minute fix (and less if possible). Once you’ve experienced this pain you’ll understand that you not imagine running a bath in the midst of a spasm and waiting to get in it.

Heating pads do also work but can take 20 minutes to take effect and that is simply too long for most people.

The first solution for in-the-moment relief (takes 2 to 12 minutes)

After the first episode I started searching online and because I didn’t know it was called proctalgia fugax I searched for “rectal cramp”, “rectal spasm”, “anal cramp” and came across forums with hundreds of women asking about it and describing their pain.

But no-one really had a solution and many had seen their doctors without much success. The best solution I could piece together was the use of 30-60 seconds of finger pressure (with the finger wrapped in toilet paper) in the anal sphincter during a spasm. Sometimes this is needed for up to 2-3 mins and sometimes doing this 2 or 3 times a few minutes apart is needed. Think about how you put pressure on a calf muscle spasm to stop the cramps. This works well but the agony lasts for the entire 2 to 12 minutes (depending on how many times it has to be done). Refining it by adding a small amount of arnica cream onto the toilet paper helps too.

How common is it?

It took more searching and reading and then I discovered what it was called. Once I found a name for it and started looking into I was surprised to see how common it is:

The prevalence of proctalgia fugax in the general population may be as high as 8%–18%. Many patients present to primary health care physicians and often do not require further consultation because the symptoms are fleeting. This condition is more common among women than among men, and usually affects patients between 30 and 60 years of age.

Although it’s more common among women I worked with a male client who experienced this. The pain was SO bad he actually passed out and hit his head on the bathroom floor.

The best solution for almost-immediate relief (takes 1 minute)

I know that GABA works amazing well for physical anxiety and stiff and tense muscles and I decided to try GABA in the midst of a spasm. It worked amazingly well and within 1 minute the terrible pain started to ease. It does need to be taken sublingually and I have found that 250mg to 500mg opened onto my tongue works best for me.

Each person would need to find the ideal amount for their needs but at night this should be a reasonable amount. During the day this could be too much and make you sleepy or too relaxed.

I’ve also used a combination of sublingual GABA and theanine with similar results.

I know GABA isn’t readily available everywhere so I did an experiment with taurine and found I needed more (at least 1000 mg) and it did take longer (2-3 minutes) to get relief, but it did work.

THE immediate solution for preventing the spasm

But I have now gotten to the point where I can nip it in the bud and prevent the spasm altogether – by taking sublingual GABA at the very first hint of an ache or twinge. I’ve been fortunate that when this does happen (about once a month and sometimes every 2 months) it’s around 8-11pm.

The long-term solutions for getting to the root cause/s?

We always want to get to the root cause of an issue and that is the next step. I reached out to the practitioners in my community to ask them how they help their clients and patients with this and what approaches they have used to end the spasm and pain. I will be sharing some of their solutions and how to get to some of the root causes in part 2.

I’d love your feedback!

I’d love your feedback so I can learn what works, so we can all learn from each other and so others get answers quicker than I did.

Have you ever experienced this rectal pain and spasms? And what has worked for you?

I’d love to know if it is more common after sclerotherapy for hemorrhoids and vaginal hysterectomy? Have you had either? Or any surgery in the abdominal area?

Do you also have IBS/SIBO? What about celiac disease or gluten sensitivity?

Do you currently have anxiety or mood issues or have a history of anxiety or mood issues? How many low GABA and low serotonin symptoms do you have – here is the questionnaire (a paper from 1965 mentions that patients with proctalgia fugax have been described as irritable, perfectionistic, meticulous, obsessional, tense, and anxious)

If you’ve tried GABA or these other approaches (or decide to try them) please come back and share. Too many people don’t know about this and it needs to change!

Menopause: insulin, cortisol, and oxytocin (an interview with Dr. Anna Cabeca)

March 13, 2017 By Trudy Scott Leave a Comment

What should a healthy menopause look like and what does an unhealthy hormonal imbalance leads? And what is the significance of insulin, cortisol, and oxytocin?

Dr. Brian Mowll, host of the upcoming Diabetes Summit, interviews Dr. Anna Cabeca on the topic of menopause and metabolic health. Dr. Anna is a board certified gynecologist and obstetrician as well as board certified in anti-aging and regenerative medicine. She is an expert in functional medicine and an expert in women’s health.

She starts with an overview of what menopause should look like and what an unhealthy hormonal imbalance leads to:

Hormonally, what does menopause look like? Yes, we’re going to age. And we’re going to have wrinkles and laugh lines and smile lines and things like that. But that’s awesome. We should be waking up rested, going to sleep on schedule without difficulty and have the sense of peace within us that we’ve become able to enjoy the life that we’ve worked so hard to create and also be able to educate, inspire, and instruct those around us and the generations that follow us. So those are the ideals in menopause.

However, with our environment and toxicities and unhealthy aging and unhealthy hormonal imbalance, what happens is we tend to get overweight, difficulty with weight loss. We tend to have increases in our blood sugar, increases of heart disease. What that feels like, too, is hot flashes, mood swings, itchy skin, night sweats and irritability. The monster within us can come out!

The next part of their discussion is fascinating and rather unexpected. Dr. Brian asks Dr. Anna about the main hormonal players in menopause and this is what she shares:

As a gynecologist, you would think the major players would be estrogen, progesterone, and even testosterone. However, the major players when it comes to a healthy menopause are insulin, cortisol, and oxytocin. I run menopause programs specifically to get these major hormones in balance. And then we can fine tune the minor hormones.

But unless we’re getting the concepts that relate to increasing our body’s ability to have insulin sensitivity and, regarding cortisol, to have reset our cortisol, our natural circadian rhythm, we’re not going to get hormonal balance at all. And we’ll continue to struggle with the inflammation, the weight gain, the mood swings, [the anxiety and insomnia], the night sweats….

Actually, insulin and cortisol have a bigger role than estrogen, progesterone, and testosterone although those are important and DHEA as well which I will replace very frequently. But insulin and cortisol are key to healthy menopause.

And so cortisol is our natural anti-inflammatory. But also, we know that when we excrete high spikes of cortisol, that’s going to affect glucose production. So whether cortisol is too high or too low, we’re going to have an issue with glucose production and metabolism and increasing hemoglobin A1c and inflammation. So from both those areas, we’re going affect our inflammatory pathways.

Dr. Anna also covers some of the following in the interview:

Issues she sees with ketogenic diets and eating low carbohydrate diets (this one is for women in particular – she feels it throws off our neurotransmitters)
Why to test for pH and how to do it
Simple ways to boost oxytocin
Nutritional support for the adrenals

As I mentioned above, these are a few snippets from the upcoming Diabetes Summit.

In case you’re thinking “I don’t have diabetes, I don’t need to tune in to this one”, or “I’m not menopausal” or “I’m a guy” here are few points to consider:

If you’re a woman and experience stress this would be applicable whether or not you have diabetes or are in menopause (addressing this could help prevent diabetes and make menopause a breeze)
If you’re a man and experience stress this topic is also relevant, whether or not you have diabetes – just remove the words “menopause” and “women” and focus on the information about insulin, cortisol and oxytocin

So do consider tuning in to this one and other interviews in the summit!

If you do have diabetes or pre-diabetes then tuning in to the summit is a must! According to a 2015 study, nearly half the US population had diabetes or pre-diabetes. Add to that all the Americans who are overweight, obese, or have insulin resistance and other blood sugar imbalances, that number likely climbs above 75%! Unfortunately it’s not just in the US. Diabetes has become a global epidemic, predicted to get much worse in the next 20 years.

Clearly we need to do something different. Change often starts with information and inspiration. Learning the root causes of the problem and real solutions to correct those causes can motivate action.

That’s why I’m excited about this upcoming online Diabetes Summit. My friend and diabetes expert, Dr. Brian Mowll, is hosting this life-changing event for the fourth year, and this year’s event looks amazing.

I’m really pleased to be a speaker on this summit too. I cover the anxiety diabetes connection and how GABA helps reduce anxiety and how research shows it’s a promising treatment for diabetes. Read more here.

You can register for this online event here.

Vulvodynia: oxalates, GABA, tryptophan and physical therapy

February 10, 2017 By Trudy Scott 31 Comments

On a recent webinar with Julie Matthews, I shared how healthy foods that are high in oxalates caused me excruciating foot pain: Oxalates and leaky gut for Anxiety.

We also mentioned how oxalates can be a factor in vulvodynia and someone asked this question on the blog:

I just listened to the webinar talking about oxalates. I was shocked and delighted to hear the mention of the connection between high oxalates and vulvodynia. My friend has suffered with this for 18 months with little improvement. She has painful feet so I am wondering if there is indeed a connection for her situation. Could you please explain a bit more of the vulvodynia/ oxalates connection? I would like to give my friend the information.

Before I share the resources I offered her for her friend, let me share this about vulvodynia:

Vulvodynia is defined as chronic vulvar burning, stinging, rawness, soreness or pain in the absence of objective clinical or laboratory findings to explain these symptoms. Vulvodynia is a chronic pain syndrome affecting up to 18% of the female population and is generally regarded as an underdiagnosed difficult to treat gynecological disorder.

There is still much we have to learn about vulvodynia and the causes are multifactorial:

The etiology [cause] of vulvodynia is still enigmatic and is probably multifactorial-including physiological concerns (eg, pelvic floor muscle dysfunction, neuropathic pain, and psychosocial) and sexual issues (eg, anxiety and sexual dysfunction). Although it is a common syndrome, most patients are neither correctly diagnosed nor treated. A diagnosis of vulvodynia is based upon patient history and lack of physical findings upon careful examination. No clinical or histological findings are present to aid in diagnosis. Most treatment options for vulvodynia are neither well studied nor have an evidence base, relying instead upon expert opinion, care provider experience, and use of data from other pain syndromes. However, many patients show marked improvement after physical therapy for the pelvic floor, medications for neuropathic pain, and psychosexual therapy.

You’ll notice that oxalates and other dietary approaches are not mentioned. There are actually 2 studies that state there is NO connection between dietary oxlalates and vulvodynia. This is the first one: Influence of dietary oxalates on the risk of adult-onset vulvodynia. The second paper: Urinary oxalate excretion and its role in vulvar pain syndrome concludes that:

Urinary oxalates may be nonspecific irritants that aggravate vulvodynia; however, the role of oxalates as instigators is doubtful.

In this paper: Vulvar vestibulitis-a complex clinical entity, a low oxalate diet and calcium citrate did help:

Successful outcomes were achieved in 14.3% of patients using a low oxalate diet and calcium citrate supplementation

The Vulval Pain Society is a wealth of information on vulvodynvia and they have this information on the low oxalate diet, saying it helps many women and it worth trying:

A diet low in oxalate salts has been suggested as a treatment for women who experience unexplained vulval pain or vulvodynia… it is widely used in the United States as a treatment for vulvodynia. The diet may be supplemented with the use of oral calcium citrate.

There are few doctors in the UK who are aware of or routinely use this treatment. Many specialist doctors who run vulval clinics in this country [the UK] are skeptical about the treatment, as much of the evidence has not been published in the medical literature and the treatment is not of proven value. A diet low in oxalate with or without calcium citrate may, however, benefit some women with vulval pain and this is certainly an option for some women to try.

The vulvar pain is often described as a “burning” or “cutting” or “sharp” kind of pain. You’ll see medications recommended for the neuropathic pain in many of the studies and on the Vulval Pain society site.

It does concern me that so many women are prescribed SSRIs and medications like gabapentin and benzodiazepines when there are the safer and more effective options of the amino acids such as tryptophan and GABA. When dosed correctly these individual amino acids help with some of the pain and anxiety right away while other root causes are addressed.

For my clients, I recommend targeted individual amino acids instead of the medications. I recommend a trial of tryptophan instead of an antidepressant, assuming they score low on the serotonin section of the amino acid questionnaire.

Research shows there is serotonin involvement with vulvodynia. In this study of women with PVD (provoked vestibulodynia i.e. pain in the entrance of the vagina, common with vulvodynia):

Polymorphism in the serotonin receptor gene, 5HT-2A, has been associated with other chronic pain disorders such as fibromyalgia…. The results [of this study] indicate a contribution of alterations in the serotonergic system to the patho-genesis of PVD and gives further evidence of PVD being a general pain disorder similar to other chronic pain disorders.

I also recommend a trial of GABA instead of gabapentin or one of the benzodiazepines, assuming they score low on the GABA section of the amino acid questionnaire.

Tryptophan and GABA can help with both the pain, and the anxiety and depression that is commonly seen with vulvodynia and other pelvic floor conditions – right away while other root causes are addressed.

Since acupuncture is often reported to be helpful, I also consider a trial of DPA for endorphin boosting and hence some pain reduction too.

Physical therapy is often extremely beneficial and frequently overlooked, so finding a good pelvic floor PT to be part of your healing team is key too.

When responding to the blog question I commented that “your friend is fortunate to have you looking out for her”. Using some or all of the above approaches I would expect her to find some relief of the vulva pain, the foot pain and experience reduced anxiety and depression (assuming these are her root causes).

Please note that this is not an exhaustive list of contributing factors for vulvoldynia – other factors could include candida, infections such as HPV, IBS/SIBO, and trauma and sexual abuse. My colleague, Jessica Drummond, nutritionist and physical therapist, and an expert on female pelvic pain, writes about immunity, dysbiosis, gluten and other food sensitivities, cortisol and sex hormone imbalances in this article: Vulvovaginal Pain and The Immune System: Practical Steps for Vulvovaginal Pain Relief. A full functional workup is required and your root cause can be different from someone else’s root cause.

I’d also like to add that although dietary oxalates cause excruciating pain in my feet, I’m so fortunate, in that I do not have vulvodynia.

Have you had success with a low oxalate diet and calcium citrate for vulvodynia? And other pain (in the feet or hips or elsewhere in the body)?

Has physical therapy with a pelvic floor specialist helped?

Have you found tryptophan, GABA or DPA to help with the pain and the anxiety and/or depression too?

Have any other treatments helped you?

If you’re a practitioner what approaches have helped your clients/patients?

Please share questions or feedback below.

Breast cancer: DCIS, thermography, estrogen, toxins, glutathione and anxiety

October 28, 2016 By Trudy Scott 2 Comments

breast-exam

October is Breast Cancer Awareness month so I’ve gathered some wonderful information and resources for you about DCIS, thermography, prevention by addressing estrogen dominance, avoiding endocrine disruptors and environmental pollutants and finally how to boost glutathione for detoxification support.

Ductal carcinoma in situ/DCIS: many don’t even consider this cancer

My good friend and fellow nutritionist Robin Nielsen recently posted about this on Facebook and because it was so beautifully said, I asked if I could share it:

A neighbor just told me this morning that she had a double mastectomy in early August due to cancer, stage 0. And then she told me it was “Ductal carcinoma in situ”. I know many women who have reversed this by changing their diet and lifestyle. This is a touchy subject for many, but it breaks my heart to see women removing their breasts when there’s a chance they don’t have to.

If you are in the thick of this right now, trying to decide what to do, do your research. Get lots of opinions from integrative practitioners. Many don’t even consider this cancer.

And if you’ve had this done yourself, you made the right choice. Because whatever we decide for ourselves is right. Sending love out to all women who have had to make this decision.

I asked Robin to share one of her articles and here it is: What You Need to Know About Your Beautiful Breasts and Breast Cancer. These factors have a big impact on our beautiful breasts:

The food you eat: inflammatory vs. anti-inflammatory
The quality and quantity of sleep
The toxins you’re exposed to: environmental, body care and household products, poor quality foods, toxic people, toxic habits and more
Your perception of stress and our ability to manage the stress in our lives
Your thoughts
And other lifestyle factors like exercise, relationships, your sense of community, etc.
How you deal with your emotions – your ability to express yourself
Your body’s nutrient status – especially Vitamin D3
Your ability to restore, nourish and love yourself, i.e. learning how to receive
The bras you wear – studies have shown that wearing a bra that’s too tight can restrict vital blood flow and can contribute to toxin build-up in your lymphatic system

Thermography for early detection and accurate test results

A thermogram image (from http://earlybreastscreen.com/)

Here are The Best Breast Cancer Screening Tests – 6 Reasons Why I Recommend Thermography from Dr. Christiane Northrup, M.D.’s blog:

Good for young, dense breasts and implants. Younger breasts tend to be denser. Thermography doesn’t identify fibrocystic tissue, breast implants, or scars as needing further investigation.
Detect cell changes in arm pit area. The arm pit area is an area that mammography isn’t always good at screening.
Great additional test. Thermography can be used as an additional test to help women and their care teams make more informed treatment decisions.
It Doesn’t Hurt. The pressure of a mammogram machine is equivalent to putting a 50-pound weight on your breast, which can be quite painful for most women.
No radiation. Another reason the United States Preventative Services Task Force reversed its aggressive mammogram guidelines was because of the exposure to radiation. It’s well known that excessive doses of radiation can increase your risk of cancer. It’s ironic that the test women are using for prevention may be causing the very problem they’re trying to avoid in the first place! And this doesn’t even touch on the harm done to the body from unnecessary biopsies, lumpectomies, mastectomies, chemotherapy, radiation treatment, and so forth.
Thermography is very safe. Thermography is even safe for pregnant and nursing women! It’s merely an image of the heat of your body.

Estrogen dominance as a cause of breast cancer and how to prevent it by eating for hormonal balance

Magdalena Wszelaki, founder of Hormones Balance, shares some signs of estrogen dominance as the leading cause of breast cancer: Breast Lumps? Thyroid Nodules? Horrendous PMS? Endometriosis? In her wonderful article: The Breast Cancer and Estrogen Link | 15 Ways to Prevent and Manage Breast Cancer Naturally, she covers how to move from fear to empowerment and prevention by eating for hormonal balance. The article covers estrogen dominance in detail addressing:

Most Breast Cancers are not Genetic
How Breast Cancer Forms and Multiplies
How Estrogen Feeds Cancer
Signs of Estrogen Dominance (ED)
Not All Estrogens Are Bad

But the big takeaway is that as Magdalena says:

You have more power over your risk of breast cancer than you think. There are many steps you can take to protect yourself. Each one of them has other positive domino effects for your hormonal balance and overall health.

She shares how to rotate seeds into your diet to balance hormone levels, how to increase cruciferous vegetables like kale, broccoli, cauliflower and cabbage and how to love your liver. Here are some of Magdalena’s tips for supporting your liver which she calls the “Estrogen Detox Ally”:

A sluggish liver does not carry out its important job of filtering toxins, chemical byproducts and hormonal metabolites from your body. This can leave you with high circulating levels of the dangerous estrogen metabolites. For Breast Protection:

Add bitters in the form of dandelion leaves and root, burdock, chicory root, parsley, radicchio or bitters in tincture form. They stimulate bile production which then helps “flush out” estrogen and other steroid hormones.

Add fiber, my favorite being 2 tablespoons of freshly ground golden flax seed. Fiber promotes good bowel movement which is essential in carrying out the toxic estrogens. Chronic constipation can contribute to the re-absorption of antagonistic estrogens back to the blood stream.

Add one tablespoon of apple cider vinegar or half a lemon to a glass of warm water and drink it before breakfast in the morning. This helps stimulate the gallbladder to release the bile which is instrumental in “flushing out” estrogen.

Be sure to read the entire article here to read more about gut health, red meat, wine, toxins, inflammation, exercise, smoking, the birth control pill (I also covered this and FAM in a recent blog on the connection to subsequent SSRI use), sleep and finally stress and cuddling!

If you want to learn more I encourage you to check out Magdalena’s no-cost “How to Use Food To Rebalance Your Hormones” Online Workshop.

Avoiding endocrine disruptors and environmental pollutants

My friend and colleague Dr. Heather Paulson is the author of the soon to be released Textbook of Naturopathic Oncology. She is board certified in naturopathic oncology providing expert cancer care while creating a plan that restores health. She integrates her specialization in cancer and her love of nutrition, herbs, homeopathy, counseling, traditional healing, and current research to support you during your cancer journey and for cancer prevention. Dr. Paulson shares this about avoiding endocrine disruptors and environmental pollutants:

Endocrine disruptors are things in our environment that influence our hormonal system. You have probably heard about how plastics have been causing young boys to have feminine breasts. This plastic phenomenon is due to plastic disrupting the endocrine (or hormonal) system in boys. But the endocrine effects of environmental pollutants impacts both men and women. Some of the most common endocrine disruptors you are coming on contact with include plastic, pesticides, fragrances, beauty products, and cleaning products. Eliminating these from your personal environment is a critical piece of cancer prevention that is often missed.

She created this quiz How Toxic Is Your Home to help you see how well you are doing with endocrine disruptors. You can also find several checklists on her website to help you eliminate the necessary chemicals from your kitchen, yard, bedroom, and bathroom.

Boost glutathione levels to support the body’s detoxification channels

green-asparagus

And finally, my friend and colleague (and fellow South African) Kirsten Nussgruber shares the importance of reducing the toxic burden. When faced with the biggest challenge of her life – being diagnosed with aggressive breast cancer twice within a short three year period – Kirsten was forced to completely reevaluate what she believed was already a healthy lifestyle and now advocate for:

Eating clean and real food
Applying clean cosmetics and skin care products
And supporting the body’s detoxification channels

Kirsten shares the role of glutathione and ways to support body’s detoxification channels by boosting glutathione levels, often called your master detoxifier.

In its role as detoxifier it plays a crucial role in helping the body bind and get rid of many environmental toxins such as herbicides, pesticides, fungicides, insecticides, solvents, dyes, plastics, detergents and nitrosamines often found in processed foods.

Glutathione is also known to be cancer-preventing and has been found deficient in cancer patients. It can strengthen natural killer cells, a part of your immune system you want to have ready for action at all times!

In her blog post, she covers glutathione supplementation and shares a list of whole foods that boost glutathione production:
asparagus, acornsquash, avocados, broccoli, cabbage, cantaloupe, garlic, grapefruit, leeks, okra, onions, oranges, peaches, potatoes, spinach, strawberries, tomatoes, walnuts, watermelon, and zucchini.

Don’t be driven by fear and anxiety

As I said in my 2013 Breast Cancer Awareness blog: don’t be driven by fear and anxiety, instead use these wonderful resources as tools so you can be proactive and prevent breast cancer.

If you do get to a place where the anxiety and fear becomes overwhelming, don’t forget about the targeted individual amino acids like GABA and tryptophan for eliminating the anxiety and worry, obsessive thinking, negative self-talk, insomnia and overwhelm.

Here’s to beautiful healthy breasts for you and every woman!

Tryptophan for PMS: premenstrual dysphoria, mood swings, tension, and irritability

July 1, 2016 By Trudy Scott 38 Comments

pms

In a study published in 1999, A placebo-controlled clinical trial of L-tryptophan in premenstrual dysphoria, tryptophan was found to reduce symptoms of PMS when used in the luteal phase or second half of the cycle (i.e. after ovulation):

37 patients with premenstrual dysphoric disorder were treated with L-tryptophan 6 g per day, and 34 were given placebo. The treatments were administered under double-blind conditions for 17 days, from the time of ovulation to the third day of menstruation, during three consecutive menstrual cycles.

They looked at dysphoria, which is defined as a state of unease or generalized dissatisfaction with life, plus mood swings, tension (and anxiety), and irritability and they found a 34.5% reduction of symptoms with tryptophan compared to 10.4% with placebo.

The paper concludes:

that these results suggest that increasing serotonin synthesis during the late luteal phase of the menstrual cycle has a beneficial effect in patients with premenstrual dysphoric disorder.

Let me share what I see with the women with PMS that I work with:

This is very typical when I’m working with someone with PMS and anxiety and other mood symptoms. It typically takes 2 to 3 cycles for an amino acid like tryptophan to have an impact on PMS itself. But it does typically start to work right away on the less severe anxiety and mood symptoms that may also be a factor during the rest of the month.
I don’t start with 6g per day of the tryptophan but rather have each person do the amino acid questionnaire, review the precautions and do a trial of tryptophan, increasing as needed to find the optimal amount for their needs (you can read more about this here on anxiety and the amino acid overview
We often find that adding GABA helps too, as this supports progesterone production
Many anxious women I work with also have pyroluria or signs of low zinc and low vitamin B6 and adding these nutrients, together with evening primrose oil, provide additional hormonal support (and help with the social anxiety).
Other factors to consider with PMS: low total cholesterol (as cholesterol is needed to make hormones), gluten issues, adrenal function and blood sugar control, gut health and the microbiome, and liver support
And finally, we can’t forget diet and need to switch to eating a real whole foods diet free from sugar, gluten and caffeine. Coffee and chocolate in the second half of the cycle can be especially problematic for many women

Together with the tryptophan and the above approaches (if needed as we are all so different), it’s not unreasonable to get the reduction of symptoms from 34.5% (as seen with the tryptophan) down to 100%. It breaks my heart when I hear women think they have to live with PMS symptoms when they don’t have to!

Have you used tryptophan for PMS? Do you take it all month or just in the 2nd half of your cycle? What about other changes that have helped: GABA or liver support or quitting caffeine? Or something else? Please share.

Low cholesterol, tryptophan & methylation on Hormones – A Women’s Wellness Summit

March 28, 2016 By Trudy Scott 12 Comments

Just sending you a quick reminder about the upcoming summit.

You’ll learn why you don’t have to accept anxiety, depression, mood swings, headaches, constant fatigue or dramatic periods, and how to find answers from some amazing women’s health experts!

Join me and educate yourself online and no cost from April 11-18, 2016 on Hormones: A Women’s Wellness Summit.

(you can register here https://qt247.isrefer.com/go/WWH16reg/trudyscottcn/)

Understanding your hormones may sound like an impossible mission, but it’s really not. As we learn to incorporate healthier choices into our lives, we feel better. And, as women, when we feel better, we can do anything! And as I like to say we deserve to feel our absolute best all the time!

Join health coach and acupuncturist Bridgit Danner, LAc, FDNP, and the 30+ health and wellness experts she has gathered to teach you how to keep your body in sync with your life.

Even if you’re not a woman, tune in to learn more so you can understand the women in your life – your mom, your sisters, your wife, your girlfriend, your daughter. Or share this information with the women in your life. You may even pick up some ideas for yourself, for example most of my interview is applicable for men too.

Here is a snippet about the importance of cholesterol from my interview which airs on day 3: Balance Brain Chemistry to End Anxiety

A lot of people talk about concerns with high cholesterol, but if you’ve got very low cholesterol, you don’t have the raw material to make your hormones. That’s going to affect your mood. There’s actually research showing that very low cholesterol, a total cholesterol below 150 can make you more prone to mood problems and actually increase your risk for suicide.

If I see a woman with very low total cholesterol, the first thing I think about is absorption, as you just said. Have they got a gall bladder? Maybe they haven’t got enough bile production. Have they got damage to the gut, so they’re not able to absorb the nutrients that they’re eating? And when we add in extra healthy fats, and if you’re already doing that, then I would say look at the digestive component and see if that’s a factor. I’ve seen many women with hormonal issues just get their total cholesterol up, and their hormones start to balance a lot better, which is pretty amazing.

I also talk about how to figure out how much of the amino acids you may need and how to do a trial. In this snippet I’m talking about tryptophan for the low serotonin, worry-in-your-head kind of anxiety:

once you start on the tryptophan, for example, and the starting dose for tryptophan is 500mg. You start on that and you see how much did it improve? Wow, it went from an 8 or 9 out of 10 to a 6 out of ten. But I could definitely see some improvement. So after a few days, increase it. Go from 500mg to 1,000mg, twice a day. Yes, it improved 2 more notches, great. We’re making some gains, here. Then another few days later, or maybe a week later, add another one: 1,500mg, twice a day. Wow, now I’m feeling great. This is the dosage you stay on for a while until you feel like you don’t need it anymore.

If you increase it to the 1,500mg, for example, and you didn’t get any added benefits, then you would just go back to the lower dose. So it’s very individualized, it’s very targeted, meaning it’s targeted to your unique needs. Not everyone needs the amino acids. But if you score high on the questionnaire, and you do a trial and you benefit, then you know you need them. And then you just increase until you get the point of no more benefits.

And here is a snippet from Dr. Jill Carnahan’s interview – What’s the Big Deal About Methylation?:

we generally don’t treat methylation by itself. We treat it in the context of the patient. I’ll say that over and over again today because I think what I see in the internet and what I see with responses to my blog articles and things are patients saying, “Give me a protocol. I got this defect. What do I do?” It’s so important for patients to realize that just because you have a genetic defect, it does not cause disease. It’s genetics plus environment.

What is methylation? Basically, methylation is a process that’s involved in cellular repair. That repairs your DNA and RNA. All the time, we’re getting toxic insults to our body, chemicals and environmental things, foods even, and they can damage our DNA and RNA. Methylation is one of the processes that actually repairs those things so we don’t develop things like cancer.

Number two would be helping to create neurotransmitters. This is basically involved in our thinking, our mood, our concentration, our focus, our drive, and things like sleep, and ability to have just happiness and joy [and no anxiety]. People who have methylation issues will often have trouble with neurotransmitters.

Number one, repair DNA and RNA. Number two would be create neurotransmitters. Number three/number four would be detoxification, very involved in detoxification. Your processes to basically take care of toxic chemicals. Then, also, for immune system function which is related to the detoxification process.

Dr. Carnahan shares how our neurotransmitters are affected by methylation and how this impacts anxiety and depression:

The biopterin pathway is part of the methylation cycle. It actually comes from the folic acid metabolism cycle. If that isn’t running properly, this is where you make phenylalanine which is a precursor for tyrosine, tyrosine which is a precursor of dopamine, and tryptophan which is a precursor of 5-HTP.

You can also catch these great speakers on day 3 with myself and Dr. Carnahan:

Keesha Ewers – Common Causes of a Low Sex Drive
Jen Wittman – How to Have a Thyroid-Loving Lifestyle
Amy Medling – How to be a PCOS Diva

Other summit speakers cover the adrenals, low testosterone in women, PMS and missed periods, endometriosis, how to have gorgeous skin, fertility, pregnancy and post-partum, perimenopause, your hunger hormones, toxins in your food, bio-identical hormones, cell phone dangers and much much more.

I hope you join us online from April 11-18, 2016 on Hormones: A Women’s Wellness Summit

You can register here https://qt247.isrefer.com/go/WWH16reg/trudyscottcn/

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