Archives for February 2020

Imposter syndrome and low serotonin: is tryptophan the solution?

February 28, 2020 By Trudy Scott 63 Comments

No-one is talking about the biochemical and low serotonin aspect of imposter syndrome and the role tryptophan plays. This really does need to be part of the discussion and part of the solution.

In case you aren’t familiar with the term imposter syndrome, many of my clients who appear to have very successful careers will say to me … “I feel like I’m an imposter. They’re going to catch me out at what I’m doing. I’m not really as good as everyone thinks I am.” Perhaps you can relate to this? You just don’t feel that you’re good enough – you’re faking it until you make it and putting on a brave face.

I can relate to all this personally. I had a very successful corporate job in my late 30s and I started to feel sure I was useless and that I was going to lose my job. Then the dreadful perimenopausal symptoms and anxiety and panic attacks started. And then I figured out it was low serotonin and hormone imbalances (and a number of other root causes that factored in to all this – I list many typical root causes below).

Valerie Young’s excellent book, The Secret Thoughts of Successful Women: Why Capable People Suffer from the Impostor Syndrome and How to Thrive in Spite of It, [my Amazon link] has created the awareness we need and offers so much in terms of recognizing the way imposter syndrome manifests in our lives. She shares these examples which you may also resonate with:

From the high-achieving Ph.D. candidate convinced she’s only been admitted to the program because of a clerical error to the senior executive who worries others will find out she’s in way over her head, a shocking number of accomplished women in all career paths and at every level feel as though they are faking it – impostors in their own lives and careers.

This article in Harvard Business Review, Overcoming Imposter Syndrome, states

Imposter syndrome can be defined as a collection of feelings of inadequacy that persist despite evident success. ‘Imposters’ suffer from chronic self-doubt and a sense of intellectual fraudulence that override any feelings of success or external proof of their competence.

The article mentions phrases such as “I must not fail”, “I feel like a fake” and “it’s all down to luck”, offering these tools: recognise the imposter feelings, reframe, talk about how you feel, be kind to yourself, visualize success and seek support.

This is all great advice but it’s hard work when you’re already struggling. And what if there was a simple solution that involved addressing low serotonin with an amino acid supplement such as tryptophan or 5-HTP?

How you will feel if your serotonin is low

If your serotonin is low you WILL feel like this: plenty of self-doubt, lack of confidence and negative self talk. It’s common to feel anxious and inadequate, have ruminating thoughts, do lots of reprocessing and overthinking, and be a perfectionist (you may get stuck because of the perfectionism and overthinking things). This often occurs together with carb cravings (especially late afternoon and evening), PMS/perimenopausal/menopausal symptoms. Insomnia is common and this is when much of the ruminations and negative self-talk occurs.

There is a very simple solution. Figure out if low serotonin is the issue and address it with tryptophan or 5-HTP. Using co-factors like zinc, vitamin B6, iron, magnesium, and diet and lifestyle changes may be necessary too.

Why is serotonin low (and address the root causes)

You also need to figure out why serotonin is low and address this. Low serotonin may be caused by many factors such as:

dysbiosis and a messed up microbiome (we make so much serotonin in the gut)
stress and the adrenals (cortisol affects your sex hormone production)
the birth control pill (which lowers zinc and vitamin B6, both of which are needed for serotonin production)
gluten issues (leading to low serotonin and other nutritional deficiencies)
not consuming enough quality animal protein (amino acids are the building blocks of our neurotransmitters, and grass fed red meat provides zinc, iron and omega-3s – all needed to make serotonin)
low stomach acid (meaning you can’t digest the protein you’re consuming)
sex hormone imbalances (serotonin and estrogen are very closely linked)
liver issues (affecting how you process xenoestrogens)
low bile production (so you’re not digesting the healthy fats you’re eating)
statins (leading to cholesterol that is too low)
not getting enough exercise, sunshine or nature
mold exposure
heavy metal toxicity
Lyme disease and other co-infections
and more

I’ve poured through the research on imposter syndrome and there is no mention of serotonin. A few articles – like this one in Forbes, Why You Need To Understand The Neuroscience Of Imposter Syndrome – mention serotonin but not tryptophan (or 5-HTP) or any of the above approaches for raising serotonin (other than exercise).

However, clinically we see all the signs of imposter syndrome disappear once low serotonin is addressed.

Imposter syndrome and low serotonin? Have you made the connection and can you relate?

Please comment below if imposter syndrome resonates with you so we can all learn from each other. I’d love to hear:

how imposter syndrome shows up in your life and how you’d describe it to your best friend?
when do you feel like this – at work, all the time (work and home life) or only certain situations?
are these new feelings and if yes when did they start? or have you always felt like this?
what type of job do you have? or are you an entrepreneur?
have you sought help for imposter syndrome and what has helped?
are you surprised to learn there is a biochemical aspect and nutritional solutions?
what other low serotonin symptoms do you have?
have you used tryptophan (or 5-HTP) for other low serotonin symptoms (like anxiety, ruminations, insomnia etc) and then realized that imposter syndrome is not longer an issue for you?
have you figured out and addressed some of the root causes of your low serotonin?

(if you feel more comfortable sharing some of this anonymously feel free to use a nickname when commenting – I’m aware that there is a stigma to admitting this in the corporate world)

Feel free to post your questions too.

Food Fix by Dr. Mark Hyman – my review

February 27, 2020 By Trudy Scott 4 Comments

Dr. Mark Hyman has a brilliant new book called called Food Fix: How to Save Our Health, Our Economy, Our Communities, and Our Planet – One Bite at a Time and his big bold message is that: “We need to change the food system to change the world.” It is an issue that is seriously overlooked and he wants to change this.

Watch this short video clip to hear it from Dr. Hyman himself.

Here are some of the key messages from Food Fix

If we don’t change the food system, we’re going to spend $95 trillion dollars on chronic disease – heart disease, obesity, type 2 diabetes, cancer, and dementia – over the next 35 years.

Big food spends a lot of money in Washington to keep us fat and sick.

The food industry preys on our most vulnerable citizens – children.

According to the American Psychological Association, children under the age of 8 don’t instinctively recognize the difference between TV Commercials and programs, which makes them particularly vulnerable.

Big Food buys partnerships with public schools.

Minorities are also targeted by the food industry.

Researchers at the University of Connecticut found that junk food companies spend the most on ads that target African Americans and Spanish speakers. Guess which products were most heavily advertised toward minorities—Gatorade, Pop Tarts, Twix Candy Bar, Cinnamon Toast Crunch Cereal, and Tyson Frozen Entrees

The worse the nutritional profile the more heavily the products were promoted through advertising.

Where are the broccoli ads?

These findings, the researchers noted, “highlight important disparities in the food and beverage industry’s heavy marketing of unhealthy foods to Hispanic and black youth, and the corresponding lack of promotion of healthier options.”

Bad food is making us anxious, depressed, and is messing with our brains. I’m thrilled that Dr. Hyman highlights how nutritional medicine is a key to mental health and psychiatry. Here are some snippets :

Studies show that adults with many types of mental health issues and children with ADHD have very low levels of antioxidants (which come from fruits and vegetables), such as the fifty-six-year-old man with lifelong crippling depression who improved by cleaning up his diet and taking a cocktail of B vitamins. I remember one man who presented with severe panic attacks every afternoon. Turned out he was eating a diet very high in sugar and starch and had wild swings in his blood sugar, which triggered the anxiety. When he cut out sugar and starch, his anxiety and panic attacks vanished. These stories are not anomalies. They are predictable results from applying nutritional medicine.

In recent years, major medical journals have clearly shown the link between nutrition and mental health. The Lancet Psychiatry, a top medical journal, maps out just how nutritional medicine is a key to mental health and psychiatry. Overall diet quality, high sugar loads, and rampant nutritional deficiencies (including omega‑3 fats, zinc, magnesium, vitamin D, and B vitamins) all drive mental illness. In other words, the culprit is once again the American and increasingly global industrial diet. We have discussed the costs of obesity and chronic disease, but most don’t connect mental illness to the costs of chronic disease. In fact, the cost of mental illness to the economic burden is far greater than the costs of heart disease, diabetes, and cancer.

Population studies have found that more fruits and vegetables and less french fries, fast food, and sugar are associated with a lower prevalence of mental illness, and that junk food creates moderate to severe psychological distress. The good news is that interventional studies have shown that treatment of mental illness with diet works well (especially since most medications for mental illness don’t work that well, despite being the second biggest category of drugs sold).

And here are a few of the many solutions proposed in the book:

Support regenerative agriculture and sustainable food.

Stop purchasing franken-foods:

Today 60% of our diet is ultra-processed food made from commodity crops—corn, soy, and wheat—that’s turned into various sizes, shapes, and colors from the raw materials—high fructose corn syrup, white flour, and refined soybean oil. When you vote with your dollars and your fork to stay away from these foods, you send a message to big food to stop subsidizing commodity crops and grow more fruits and vegetables!

End food waste:

Buy only what you need. If food may go bad soon, make a soup or stew. Get a compost bucket for your kitchen. Start a compost pile in your backyard, or buy an in-home composter. Use it in your garden or donate it to someone who has a garden.

Be an activist and teach your family why food matters.

Address food deserts and food swamps in African American communities, and recognize that this is:

“food apartheid,” an embedded social and political form of discrimination.

Here is the official book blurb:

Help to transform the planet in crisis with this indispensable guide to healthy, ethical, and economically sustainable food from #1 New York Times bestselling author Mark Hyman, MD.

Food is our most powerful tool to reverse the global epidemic of chronic disease, heal the environment, reform politics, and revive economies. What we eat has tremendous implications not just for our waistlines, but also for the planet, society, and the global economy. What we do to our bodies, we do to the planet; and what we do to the planet, we do to our bodies.

In Food Fix, Mark Hyman explains how our food and agriculture policies are corrupted by money and lobbies that drive our biggest global crises: the spread of obesity and food-related chronic disease, climate change, poverty, violence, educational achievement gaps, and more.

Pairing the latest developments in nutritional and environmental science with an unflinching look at the dark realities of the global food system and the policies that make it possible, Food Fix is a hard-hitting manifesto that will change the way you think about – and eat – food forever, and will provide solutions for citizens, businesses, and policy makers to create a healthier world, society, and planet.

I love that Dr. Hyman says he is left with a sense of hope and possibility after writing this book … “understanding the problems and challenges we face sets the foundations for the solutions.”

Wise words indeed! This book is much-needed, brilliant, eye-opening and shocking at times, but hopeful and solution-based.

You can get your copy of Food Fix here (my Amazon link) and find additional information and resources on the official book site here.

Tapping (or EFT) for reducing anxiety, depression, pain and cravings, plus physiological changes in cortisol, heart rate, blood pressure and SigA

February 21, 2020 By Trudy Scott 16 Comments

Awareness about tapping or EFT (emotional freedom technique) is growing and so is the research. I’ve been intrigued by tapping for some time and I’m impressed by some of the very positive feedback I’ve heard about how it reduces anxiety, depression, pain and cravings. I’m now more intrigued after reading a 2019 paper that describes some of the physiological changes (i.e. changes in the body) that improve after tapping.

This paper, Clinical EFT (Emotional Freedom Techniques) Improves Multiple Physiological Markers of Health, describes EFT as “an evidence-based self-help therapeutic method”, reporting that “over 100 studies demonstrate its efficacy.”

It’s further described as “a brief intervention combining elements of exposure, cognitive therapy, and somatic [or physical] stimulation of acupressure points on the face and body.” The full paper here goes into great detail if you’d like to read more.

The objectives of this study were to measure and describe some of the physiological changes that occur after tapping, in order to understand some of the mechanisms. Up until now “information about the physiological effects of EFT is limited.”

As far as physiological changes, these included: heart rate variability and heart coherence, resting heart rate and blood pressure, salivary cortisol (to show changes in the endocrine system), and salivary immunoglobulin A (SigA) (to show impacts on the immune system).

They also measured these psychological symptoms: anxiety, depression, posttraumatic stress disorder, pain, and cravings. After a 4-day training workshop on tapping, the researchers reported that happiness increased by 31% and the following declines in psychological symptoms in 203 participants were reported:

anxiety (-40%)
depression (-35%)
posttraumatic stress disorder (-32%)
pain (-57%) and
cravings (-74%)

These physiological improvements were found in the subset of 31 participants that were tested:

resting heart rate (-8%)
salivary cortisol (-37%)
systolic blood pressure (-6%) and diastolic blood pressure (-8%)
heart rate variability and heart coherence
salivary immunoglobulin A (SigA) (+113%)

The authors conclude that

gains were maintained on follow-up, indicating EFT results in positive health effects as well as increased mental well-being.

If you’ve been following me for awhile you know I like to look into the research so I’m excited by this study and look forward to further research and gaining a better understanding of this tool.

I also look forward to learning how lasting these psychological and physiological changes are and if you need to keep tapping in order to sustain the changes.

Possible impacts on boosting neurotransmitter levels

Because of the psychological benefits I was also curious about the possible impacts of tapping on boosting neurotransmitter levels such as GABA and serotonin. I found this research on acupuncture which we may be able to partially extrapolate from since EFT does have the acupressure aspect: Effect of Acupuncture on Neurotransmitters/Modulators

In general, acupuncture enhances the activity of the endogenous opioid peptides, serotonin, dopamine, ACh [actelyl-choline], and inhibitory amino acids such as γ-aminobutyric acid (GABA), glycine, taurine, and lactamine, while it attenuates the activity of noradrenalin and excitatory amino acids including glutamate and aspartic acid.

Compliments the dietary/nutritional/biochemical approach

Based on what I’ve been recently learned, tapping compliments the dietary/nutritional/biochemical approach I use my clients for helping to ease anxiety, overwhelm and stress.

I reached out on Facebook and here is some of the feedback I received:

Maria shares how she uses both EFT and tryptophan: I started using EFT and it has helped – wasn’t expecting it to, but it really does work. However, having had a particular problem for many years, I realize that it’s going to take time to really be at the level I want to be. I also got a teenager to try it, and to their amazement, it did settle their anxiousness – from what they initially said was a 10 -11 – down to 7 in just a few minutes. Last night, I tried the Lidtke Tryptophan and couldn’t believe how deeply and undisturbed I slept – thank you Trudy – I learnt about that product from you during the anxiety summit. By the way, I will be joining the Tapping Summit – can’t wait for that one!

Terri Hirning is a practitioner and shares that her and her biz partner bring it to their clients in conjunction with lifestyle changes for maximum effect. She shares: I find that anxiety is a big issue for my clients. So while they are implementing dietary or supplement changes, tapping can help reduce those emotions while their biochemistry comes into alignment.

She also says: I taught it to my children and they have The Tapping Solution app and will proactively use it when they need to shift things. I am so thankful for this work.

Meeta Darji is a health coach and says this: YES! EFT is profound in helping with anxiety and stress. I have been doing it for the last two years and use it on my kids too. I’m training at the moment and learning how it can help with cravings and addictions. Absolutely incredible and I can’t wait to add it to my health coaching practice.

She does use amino acids like GABA, tryptophan, DPA, glutamine for anxiety and cravings/addictions and agrees that EFT is definitely a good compliment. EFT is great for using with limiting beliefs, traumas, addictions, fears and so much more, so together with amino acids, it’s very powerful.

Benita Scott shares this: EFT is so great! I use it as part of my professional practice as a psychologist and in conjunction with Nutritional therapies it’s a game changer for so many vulnerable clients. It’s been shown to increase GABA levels, decrease cortisol and alter brain cells in relation to food cravings too. There has been a paradigm shift in psychology recently and I think EFT, Matrix and nutritional supplements are changing how we work and heal.

Dede shares how EFT changed her life: I was on permanent disability for 20 years due to panic attacks. EFT changed all that so I became a practitioner. This was 11 years ago.

She shares how she went through “the literal hell of getting off psych meds. I wouldn’t have survived without EFT and food changes.”

It does seem to be very individualized and works very well for some folks and not very well or not at all for others:

One person said EFT is soothing in the moment but she didn’t find any significant or lasting benefits.
Someone else shared: I have tried it, my daughter and her son went to a practitioner, and it did nothing for me or them. I have studied how to do it on-line from well known sites, and still nothing. I’m wondering if a lot of healings are the placebo effect.
It doesn’t seem to work for me either (more on that below)

My tapping experience is very limited

I will admit that, at this point, my tapping experience is very limited. I have such great success with amino acids like GABA, tryptophan and glutamine to provide quick anxiety-relief, end the overwhelm and stop the carb cravings for my clients, I haven’t felt the need to look into tapping.

In case you’re new to me and my work, here is a sampling of a few tools I use with my anxious clients:

My main approach is using targeted amino acids such as tryptophan or 5-HTP for the low serotonin worry-in-your-head anxiety where folks may also experience fears, panic attacks, ruminations, phobias, insomnia, PMS, anger, irritability and cravings; and GABA for the low GABA physical-anxiety that also includes muscle tension, overwhelm, insomnia and the need to self-medicate with alcohol to calm down
Another amino acid is DPA (d-phenylalanine) and I’m mentioning this one because it boosts endorphins (in a similar way to acupuncture) and helps my clients who are experiencing weepiness, pain and are big comfort/reward eaters. I blog about this here: DPA for weepiness, pain and comfort and reward eating)
Since the EFT study mentions cortisol, I’ll share one of my key nutrients for lowering cortisol – Seriphos (I blog about this here: Seriphos Original Formula is back: the best product for anxiety and insomnia caused by high cortisol)
And of course everything else: diet, no sugar, no caffeine, gut health, improving sleep, toxin removal and addressing all nutritional deficiencies etc (covered in great detail in my book “The Antianxiety Food Solution” and elsewhere on this blog.)

I’m getting newly acquainted with EFT

I have been hearing about tapping/EFT for years – first from Dr. Mercola and then had a group session at a conference with Brad Yates and didn’t notice any benefits. I’ve tried it again a few times and have yet to experience any profound benefits. I’d expect to be a good candidate given my history with anxiety/insomnia.

I really do like to be able to share resources and products I have experienced personally but in this instance I’m still a newbie.

As of now I don’t know why tapping/EFT doesn’t help me and some other folks. Perhaps there is a bioindividual aspect? Just like some folks do well with herbs and some with vitamins/amino acids; some folks thrive on spinach and some have oxalate issues; some folks do well with meditation and others struggle with it; some find nature to be an elixir and others find dancing to be their magic?

However, based on what I’ve recently learned about the physiological changes and the feedback I’ve heard, I’m getting newly acquainted with EFT and it’s an additional resource I want to offer you – my community of anxious women.

Right now I’m seeing it as another tool in the toolbox (for some folks), together with dietary changes, addressing biochemical imbalances, gut health, getting out in nature etc.

Resources for additional learning

If you’re new to tapping and would like to learn more, the 13th Annual Tapping World Summit airs online Feb 24 – March 7. Here is the main summit registration page.

This is a great introductory video from summit host Nick Ortner (register to watch it and get access to the summit)

I’d love to hear back from you in the comments below

Do you use tapping/EFT in conjunction with dietary/nutritional/biochemical changes to help ease your anxiety, stress, overwhelm? (if you’re a practitioner, do you use both with clients/patients?)
Do you find one approach to be better than the other?
Have you tried tapping without success?
If you’re new to tapping/EFT are you interested in learning how to incorporate it into your life?

Please share so I can learn from you and we can all learn from each other (and thanks to everyone who has contributed to the discussion already).

Microdose lithium formulation is capable of halting signs of advanced Alzheimer’s and improving cognition

February 7, 2020 By Trudy Scott 45 Comments

In a new study, a team of researchers has shown that, when given in a formulation that facilitates passage to the brain, lithium in doses up to 400 times lower than what is currently being prescribed for mood disorders is capable of both halting signs of advanced Alzheimer’s pathology and of recovering lost cognitive abilities.

The above snippet is from a press release published last month on Science Daily: Can lithium halt progression of Alzheimer’s disease? Keep in mind that this is an animal study but the results are so promising. I’m also very intrigued by the delivery method (more on that below).

In order to give this microdosing context, a typical adult prescription for is 900-1800mg lithium carbonate/day. I reached out to the lead author for clarification about the dosing of this new formulation and lead researcher Dr. Cuello shared this with me:

I calculate that our lithium dosage is 285 times lower concentration than the 900 mg dose (based on 70 kg of body weight) and 570 times lower than the 1800 mg dose.

This translates to around 3.2 mg to 6.4 mg NP03 based on 70kg of body weight (which is around 154.3 lbs).

NP03 is a disease-modifying nano dose formulation of lithium citrate which is used sublingually. I assume it’s not yet commercially available.

Also from the press release: “our findings show that microdoses of lithium in formulations such as the one we used, which facilitates passage to the brain through the brain-blood barrier while minimizing levels of lithium in the blood, sparing individuals from adverse effects, should find immediate therapeutic applications.”

Here is a link to the actual paper: NP03, a Microdose Lithium Formulation, Blunts Early Amyloid Post-Plaque Neuropathology in McGill-R-Thy1-APP Alzheimer-Like Transgenic Rats

Can we compare NP03 to low dose lithium orotate?

What is really interesting is that low dose lithium in the form of lithium orotate is commonly recommended by integrative practitioners for anxiety, mild mood swings, brain fog, ADHD and insomnia. I have found it to be extremely beneficial for many of my clients and have used it personally with success (for brain fog and insomnia).

Just how much lithium orotate is low dose? Typical doses are 5-10 mg per day, increasing to 20mg per day.

Can we compare NP03 to low dose lithium orotate? It’s too early to know for sure but we I believe we can start to make extrapolations, especially given that both are very low doses.

Integrative psychiatrist, Dr. James Greenblatt, MD has written extensively about low dose lithium orotate for the above purposes and for Alzheimer’s too. In this article, Lithium: The Cinderella Story About a Mineral That May Prevent Alzheimer’s Disease, he shares that

Scientists first became interested in the use of lithium for treating neurodegenerative disorders when they observed that bipolar patients using lithium therapy seemed to have lower rates of cognitive decline than peers on other medications.

He writes how an enzyme called Glycogen Synthase Kinase-3 (GSK-3) – a serine/threonine protein kinase – normally plays a major role in neural growth and development and how lithium

works as a direct GSK-3 inhibitor… halting inappropriate amyloid production and the hyper-phosphoryation of tau proteins before they become problematic.

If all this fascinates you as much as it does me, Dr. Greenblatt writes more about lithium orotate in his excellent book: “Nutritional Lithium: A Cinderella Story: The Untold Tale of a Mineral That Transforms Lives and Heals the Brain” (my Amazon link).

Alzheimer’s and cognitive decline have many root causes

Keep in mind that Alzheimer’s and cognitive decline have many root causes that must be considered. This may include inflammation, stress and candida, and even insecticide exposure.

Benzodiazepines have also been linked to increased Alzheimer’s risk which is why a nutritional approach for anxiety is the best approach. Let’s use the amino acids like GABA (for physical anxiety), and tryptophan (for worry and fears), as well as dietary changes and improving gut health instead of anti-anxiety medications.

The best Alzheimer’s book

The best Alzheimer’s book is “The End of Alzheimer’s: The First Program to Prevent and Reverse Cognitive Decline” by Dr. Dale Bredeson (my Amazon link). He doesn’t mention lithium orotate so I look forward to hearing his thoughts on this new research. [I’ll come and update the blog when I do]

You can read about some of Dr. Bredesen’s work here: Alzheimer’s disease, mercury and mycotoxins

I look forward to human clinical trials of NP03. Dr. Cuello “ believes that there is an excellent opportunity to launch initial clinical trials of this formulation with populations with detectable preclinical Alzheimer’s pathology or with populations genetically predisposed to Alzheimer’s, such as adult individuals with Down Syndrome.”

I would also love to see lithium orotate compared to NP03 in future research.

In the meantime I feel this early research is exciting because it supports some of what is being seen clinically with lithium orotate.

Have you used lithium orotate with success? How much has helped you and have you seen cognitive benefits? What about a more even mood, better sleep and less anxiety?

And have you or a family member seen improvements with the Bredesen protocol?