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Mental health

More kids are showing up in ERs with anxiety, depression and other common mental health problems: why isn’t nutritional psychiatry part of the discussion?

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This article on NBC news, More kids are showing up in ERs (Emergency Rooms) with mental health crises, reports large increases across the country.

Dr. Anna Abrams, a pediatrician and researcher at Children’s National Medical Center in Washington, finds the numbers both shocking and disheartening.

In the 5-year period from 2012 to 2016, when looking at ER mental health admissions in 45 children’s hospitals, they found the following increases:

  • 48 % in white children
  • 64% in non-Hispanic black children
  • 77% increase in Hispanic children

with about a 55 % increase overall.

Dr. Abrams and her colleagues presented these findings at the American Academy of Pediatrics conference in earlier this month.

Other than the very large increases, there is something else to be concerned about: the researchers say they aren’t sure why we are seeing these increases, speculating it “could be due to the scarcity of mental health professionals who can help children” and “People are also talking more openly about depression, anxiety and other common mental health problems and that may make parents feel more comfortable about seeking help for their children.”

While these are very valid reasons, we really do need to be incorporating nutritional psychiatry (a term coined in 2015) and functional medicine (Dr. Mark Hyman is one of the leaders in functional medicine) into these discussions, studies and conferences. Other than poor diets and nutritional deficiencies we need to be considering stress, exposure to toxins, poor gut health and increasing Wifi exposure, to name a few.

If we look at diet alone, there is so much recent research supporting the connection between diet and mental health. Here are two of many new studies:

Despite some contradictory results, overall there was support for an association between healthy dietary patterns or consumption of a high-quality diet and lower levels of depression or better mental health. Similarly, there was a relationship between unhealthy diet and consumption of low-quality diet and depression or poor mental health.

These data suggest that Iranian adolescent females eating a pro-inflammatory diet…had greater odds of having at least moderate depressive symptoms.

And here are just a few other factors to consider:

How do we get this nutritional psychiatry research and case studies into the hands of those who can change actually policy and the way mental health is addressed? I believe it has to be a grass-roots effort from the bottom up and I have these suggestions:

  • share this blog and the research with your doctor and/or allied health practitioner
  • reach out to study authors, journalists and legislators and share research and success stories like the above, and your own personal results
  • if you’re a practitioner, write blogs like this sharing the good results you see with your clients and patients – with researchers, journalists and legislators
  • share in forums and on social media, and with your neighbors, friends and family
  • comment on blogs like this – with success stories in your family or with clients – so more people get to see what really is working

Every little bit helps! I’d love to hear your ideas too.

The Broken Brain highlights: Trudy Scott interviews Dr. Mark Hyman

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I’m really excited to share my in-person video interview with Dr. Mark Hyman, MD. It’s an interview I arranged because I’m so excited about his Broken Brain docu-series which will start airing on January 17th. You may have seen it when they recently did a test launch but if you haven’t yet seen the series it is well-worth watching and is highly recommended! (Registration link here)

In this interview with Dr. Hyman we talk about root causes of anxiety, depression, dementia, Alzheimer’s disease and ADHD: medication side-effects, diet, the microbiome, nutritional deficiencies, brain chemical imbalances, heavy metal toxicities and more; he shares his personal mercury toxicity story and the why behind the Broken Brain series; we cover off-label medications, trauma, labels and functional medicine.

I love the term he uses to describe body-mind medicine (which is different from mind-body medicine): somatopsychic = mental symptoms caused by bodily illness i.e. all of the above root causes.

One of the big reasons I’m supporting The Broken Brain docu-sersies is that it offers solutions and plenty of hope!

Here is the interview and transcript.

(there are captions on the video – if you don’t see them be sure to click the CC on the bottom right)

Trudy: – Welcome, it’s Trudy Scott here, food mood expert, certified nutritionist, author of The Antianxiety Food Solution, host of The Anxiety Summit, and today I’ve got the pleasure of interviewing Dr. Mark Hyman, who is the creator and host of the new Broken Brain series, and I’m just really excited to be here. I’ve been such a fan of yours for so many years. I know my community knows who you are, and they’re really excited about the Broken Brain series. I wanted to get together with you, and give some highlights, and talk about firstly why you created the Broken Brain series, and you’ve got a story behind your passion about it.

Dr. Mark Hyman: – I do. I do. Thank you for having me. Yeah, so about 20 years ago, I went from being a very healthy young doctor to having a broken brain, and a broken body, and it turned out it was from mercury poisoning that I got when I was in China, and I just developed severe chronic fatigue, where I couldn’t focus, I couldn’t remember, I couldn’t think, I couldn’t pay attention, I was depressed, I couldn’t sleep, I felt just completely not myself, and through that journey, was able to discover this world of functional medicine, which I thought was fairly developed at the time, but was really just in its infancy, and through discovering functional medicine, I was able to repair my own system, and fix my broken brain. I began to apply this with patients, seeing all kinds of things, without really knowing what I was doing, I was just treating people’s physical systems, fixing their gut, helping their immune system, cleaning up their diet, optimizing their nutritional status, balancing their hormones, and all their mental problems would get better. Their anxiety would get better, their depression would get better, and I wasn’t actually treating the depression or anxiety. Autism, ADD, memory issues, dementia, all these things would start to get better, and I began to realize that the body was driving a lot of this brain dysfunction, and that if you fix the body, a lot of the brain disorders would get better, that it wasn’t a primarily a mental problem, but it was a physical problem. Just as there’s a mind body effect, which is real, there’s also a body mind effect and that hadn’t been really talked about, so I wrote a book called The UltraMind Solution 10 years ago, which outlined this model, and then really this has been an incredible 10 years of brain research that I felt needed updating, and so we created a documentary series online looking at the new research, and how this applies, and the things that I noticed 10, 15, 20 years ago are now becoming more and more accepted and understood as real, and so we’re able to actually work with people in a very specific and direct way to help heal their broken brains, and to help people recover from things that we thought were really irreversible, not just anxiety, depression, but ADD, autism, dementia, Parkinson’s, all sort of issues that affect the brain that have a very different approach that can be used to repair and heal.

Trudy: – That’s so powerful, and I love that you talk about this effect that the body has on the brain, because we know about mind body medicine, you talk about that in the series, about how we can use our mind to affect our health, but you use this term. Tell me what the term is that you use that talks about how physical issues in our body, nutritional deficiencies, imbalances, can actually affect the brain.

Dr. Mark Hyman: – You mean the body mind effect?

Trudy: – Yes.

Dr. Mark Hyman – Yeah.

Trudy: – You’ve give it a term, and it was called?

Dr. Mark Hyman: – Oh, somatopsychic.

Trudy: – Somatopsychic, yes.

Dr. Mark Hyman: – We think of psychosomatic, but there’s also a somatopsychic phenomena. I would say if you have mercury poisoning, or you have a thyroid problem, or you have abnormal gut flora, or you’re vitamin D deficient, or B12 deficient, it’s very hard to have a proper functioning brain. You can’t just say someone’s got depression, that’s what’s causing their hopelessness, and helplessness, and sadness, and maybe many other things, it could be psychological, it could be a trauma, but it also could be so many other factors, and they often are overlooked and ignored, and when I start peeling back the layers of what’s happening with these people, and looking underneath the hood, and looking through the functional medicine lens at the body as a system, and correcting the imbalances, it’s shocking to me what happens. I always remember when I start applying this, I was like, wow, you got better? I can’t believe it. You shouldn’t really get better, according to Western medicine.

Trudy: – Amazing, and you mention trauma. Even if someone has experienced trauma, if their nutritional status is good, they’re able to deal with it better.

Dr. Mark Hyman: – Right.

Trudy: – And maybe have less symptoms of post-traumatic stress.

Dr. Mark Hyman: – That’s right.

Trudy: – If they have a good nutritional status, and there’s a lot of good research supporting that.

Dr. Mark Hyman: – Absolutely.

Trudy: – You talk about that in the series as well.

Dr. Mark Hyman: – Yeah, absolutely. Your brain has the ability to be resilient, but if you’re nutritionally depleted, and if you’re having all sorts of inflammatory problems, if you’re eating foods you’re reacting to, or allergic to, your brain can’t work properly, so your baseline is going be much lower, but if you fix all those things, then your capacity to deal with your psychological issues, it’s not that they don’t exist, it’s that your ability to cope with them, to work through them, to heal and repair the more difficult things, which are early life traumas, or abuse, or addiction, these are much easier to deal with once you fix the basic constitution of the person.

Trudy: – Right. Now one thing that you talk about a lot in the Broken Brain series, which I really appreciate, is the fact that there’s so much over-medication.

Dr. Mark Hyman: – Yeah.

Trudy: – Can you talk a little about it today? And I know with your story, you also had anxiety, depression, and you were prescribed medications as well.

Dr. Mark Hyman: – Yeah.

Trudy: – So this is common.

Dr. Mark Hyman: – Yeah.

Trudy: – You talk about antipsychotics. You shared some pretty scary stats on the increase that we see.

Dr. Mark Hyman: – When you look at it, it kind of goes up and down, but psychiatric medication as a whole, is the number two or three most prescribed category of drugs in America, and increasing across the globe, and it’s being used instead of dealing with the real issues, and they don’t really even work that well. I mean, anxiety medications can work, but antidepressants have been shown really not to work that well for mild to moderate depression. For severe depression, they can be helpful, and they can be life saving for some people, but they’re not a panacea, and when I was a kid, there was that one kid in the class, Patty Ainsworth, who was a troublemaker. Now it’s like 10% of the class is on ADD medication. That’s a problem.

Trudy: – It is.

Dr. Mark Hyman: – And when we see one in four people have depression in their lifetime, and if the knee jerk reaction is medication, it just sort of gives people a sense of numbness, but it doesn’t really deal with the issue. So I think we are way over-medicated, and on top of that, there’s pushing of medications for off-label use, which means that they’re not approved for those indications. So they’re doing this for kids with antipsychotics, and they’re actually been sued. So the pharma companies have been held liable for promoting these drugs for off-label uses, which they’re not allowed to do, for kids. They get fined billions of dollars, but they don’t care because they’ve made umpteen more billions, and they just see it as a marketing expense. So it’s really discouraging to see what happens to the pharmaceutical use in this space, because even for example, ADD is so fixable by dealing with the root causes, and most of us not are not even trained how to think that way.

Trudy: – That’s why I love the Broken Brian series, because it offers a message of hope, offers some practical solutions, and it empowers the person who’s suffering from the brain disorder, whatever it is, anxiety, depression, dementia, you name it, empowers them with solutions, and I think the other thing is it’s going to give curious practitioners who are not on board with this functional medicine approach some insights into what the future may hold, which I think is very promising.

Dr. Mark Hyman: – Yeah. It’s very powerful. I remember this guy who read my book, The UltraMind Solution, which is really what the Broken Brain series is based on, and he was a doctor, and he had a kid with autism, and he said, “We’re so desperate. Our kids was five, he wasn’t talking. We just started with the diet. We just got him off gluten, casein, and a few days later, all of a sudden, he started talking in full sentences,” and this is a skeptical physician who witnessed this, and I see this all the time. Patients, for example, have Alzheimer’s, or dementia, or diagnosed with dementia, and it turns out they have other issues. They have heavy metal poisoning, or they might have Lyme disease in the brain, or they might have severe nutritional deficiencies, or they might be insulin resistant with high levels of sugar in their diet that are affecting their brain, and you can fix those things. There may still be issues left over, but it’s going to be much easier to deal with those after.

Trudy: – Get to the root cause, and address those root causes.

Dr. Mark Hyman: – That’s right. That’s the purpose of functional medicine, which is a medicine of why, not what, and we have all these labels, but you know, if someone comes into my office, and they’re hopeless, and helpless, have no interest in life, can’t focus, can’t sleep, don’t want to have sex, I know what’s wrong with you. Depression, but depression isn’t the cause of those symptoms, it’s the name of the symptoms. It doesn’t tell you what’s really wrong with that person. It’s could be a host of things, from low thyroid, to gluten, to mercury poisoning, to vitamin D deficiency, to B12 deficiency, to insulin resistance. All these factors can lead to depression. Same syndrome, but different causes. So I’m much more interested in addressing the causes, then you don’t have to use the medication.

Trudy: – And some people have an issue with gluten, and have autism symptoms, and someone else can have depression or anxiety or dementia.

Dr. Mark Hyman: – That’s right.

Trudy: – So it can affect different people in a different way.

Dr. Mark Hyman: – That’s a very good point. So in functional medicine, we see that one disease can have many causes, but on the other hand, one causative factor can create many diseases. For example, heavy metals may cause dementia, or autism, or depression, or anxiety, or insomnia, or gut issues can cause all these various things that are not one disease, or for example gluten, like you mentioned, can cause autoimmune disease, can cause cancer, can cause diabetes, can cause osteoporosis, can cause anemia, can cause depression, can cause even dementia. So how do you begin to think about it? Our current naming of diseases doesn’t make any sense. So all the labeling, if you look at the diagnostic criteria, we have something called the DSM-5, which is the diagnostic and statistical manual that categorizes and catalogs all the psychiatric disorders, and they’re all categorized by symptoms. So it’s all descriptive. It’s says if you have these five symptoms, you have this, but it doesn’t tell you why, and it doesn’t really help you, other than giving you a label, which doesn’t mean anything about helping you understand what’s really going on.

Trudy: – And then you’re on a medication that’s going to give you side effects, and not actually get to the root cause of the problem.

Dr. Mark Hyman: – Right.

Trudy: – And yeah, just make some nutritional changes, addressing the thyroid, getting off gluten, addressing the gut – big session in the Broken Brain series.

Dr. Mark Hyman: – Yeah, it’s huge.

Trudy: – The gut brain connection.

Dr. Mark Hyman: – I mean, we’re just learning about this. For example, for years one of the main ways I treated the brain was fixing the gut, and that means optimizing the flora, getting rid of bad bugs, helping heal leaky gut, and we just did it, we didn’t really have a deep understanding other than we knew the microbiome was important, but now we know, for example, that there are more bacterial molecules in your blood than your own molecules, that you have 10 times as many bacterial cells in you as your own cells, 100 times as much bacterial DNA, and that DNA is all producing proteins, and all those proteins, you have 20,000 genes, there’s two million genes of bacteria in you, and they’re all producing molecules that are entering your blood stream, and driving all sorts of biological reactions, that aren’t even human molecules. So we have to begin to sort of how do those affect the brain and what’s going on? And it’s very powerful.

Trudy: – And so much research in this area, it’s just growing and growing.

Dr. Mark Hyman: – Yeah.

Trudy: – So you mentioned earlier that you wanted to do this because of all the new research. There is so much research on the gut brain connection, nutritional psychiatry. Dr. Drew Ramsey talks about this recent study on depression, and just getting people onto a real whole foods diet, and how 30% saw remission of symptoms, just changing their diet.

Dr. Mark Hyman: – Of course.

Trudy: – Not even going gluten free. So it’s powerful. These small changes can have powerful effects.

Dr. Mark Hyman: – Profound, profound effects

Trudy: – Well, thank you so much.

Dr. Mark Hyman – Thank you.

Trudy: – For your wonderful work that you do. And for making time today. I highly recommend the Broken Brain series with Dr. Mark Hyman, all the wonderful experts.

Dr. Mark Hyman: – Oh, so many. We’ve got 57 experts.

Trudy: – Amazing, some of our favorite functional medicine practitioners.

Dr. Mark Hyman: – Yeah.

Trudy: – Thank you.

Dr. Mark Hyman: – Thank you.

(I’m a tad disappointed that there is the background noise of people talking – and apologize – but I am hoping the great content overrides this and it’s not too distracting.)

Save the date for the 8 -part Broken Brain docusersies, hosted by Dr. Mark Hyman – and register here. It airs January 17-25th

Here’s a list of ALL the episodes, to showcase just some of what you will have access to. Each episode will be available for 24 hours, at no-cost!

  1. The Broken Brain Epidemic / My Story (January 17)
  2. Gut Brain Connection: Getting to The Root of a Broken Brain (January 18)
  3. Losing Your Mind (Alzheimer’s, Dementia, MS, and More) (January 19)
  4. ADHD and Autism (January 20)
  5. Depression & Anxiety (January 21)
  6. Traumatic Brain Injury: Accidents, Sports, and More (January 22)
  7. 7 Steps to An UltraMind (Part 1) (January 23)
  8. 7 Steps to An UltraMind (Part 2) (January 24)

I hope you enjoy it and get as much out of it as I did!

I actually flew from Sydney to LA for this opportunity to meet and interview him, and share more about the Broken Brain series, and I’m so glad I did! It was the first time I’d met Dr. Hyman in person and it truly was an honor to be in the company of this great man who is doing so much in the functional medicine world! Again, here is that link to register

Please share if any of this resonates with you – what solutions you have found have helped you and/or what you are working on addressing now?

AN UPDATE: there has been some feedback on the term “broken brain” being too negative and even scary so I gathered some feedback and share it in this blog: Is the term ‘broken brain’ hopeful and real or too negative and scary? I really want to hear your thoughts if you are offended by the term broken brain.  I also want to share Dr. Hyman’s apology.

Midday bright light therapy for bipolar depression

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A recent study from Northwestern University and published in The American Journal of Psychiatry: Adjunctive Bright Light Therapy for Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Trial has found that midday daily exposure to 7,000 lux bright white light for 6 weeks, significantly decreased symptoms of depression and increased functioning in people with bipolar disorder.

The press release issued by Northwestern University reports as follows

Previous studies found morning bright light therapy reduced symptoms of depression in patients with Seasonal Affective Disorder (SAD.). But patients with bipolar disorder can experience side effects such as mania or mixed symptoms from this type of depression treatment. This study implemented a novel midday light therapy intervention in an effort to provide relief for bipolar depression and avoid those side effects.

Compared to dim placebo light, study participants assigned to bright white light between noon and 2:30 p.m. for six weeks experienced a significantly higher remission rate (minimal depression and return to normal functioning). More than 68 percent of patients who received midday bright light achieved a normal level of mood, compared to 22.2 percent of patients who received the placebo light.

Images used with permission from Northwestern University

How the 7,000 lux bright light therapy was used

Here are the details of how the 7,000 lux bright light therapy was used in the study:

The light therapy patients were instructed to place the light box about one foot from their face for 15-minute sessions to start.

Every week, they increased their exposure to the light therapy by 15-minute increments until they reached a dose of 60 minutes per day or experienced a significant change in their mood.

Study lead author Dr. Dorothy Sit shares that starting low and slowly increasing the treatment made it more tolerable. None of the study participants experienced side effects, likely because the treatment was customized for each patient:

No one experienced mania or hypomania, a condition that includes a period of elation, euphoria, irritability, agitation, rapid speech, racing thoughts, a lack of focus and risk-taking behaviors.

A noticeable mood improvement with bright light therapy was also noticed as quickly as four weeks, which is similar to other light therapy research for non-seasonal depression and depression during pregnancy.

How do you do this in the middle of a work day?

You may have concerns about doing this at midday as this facebook follower voiced:

I guess if your bipolar depression is so debilitating that you cannot hold a job, then this is worth trying.

But 60 minutes!! What working person has 60 minutes in the middle of their workday?

It’s very doable because there are very nice desk versions that could easily be used at work (without anyone knowing – if privacy is a concern) or at a home-office desk for your convenience. I share some examples in this blog – Winter blues or SAD: light therapy.

I have tried lights in the morning but found that it caused agitation

I also received this feedback about increased agitation:

I have tried lights in the morning but found that it caused agitation. Over time my tolerance went down so that I could only use for less than 5 minutes. I haven’t ever tried midday light though. I’m not bipolar but I have depression which is generally worse in the winter. Exercise helps.

It may be worth trying midday light therapy if morning light therapy causes agitation or other adverse effects.

The press release mentions that light therapy is typically used in the morning to help reset circadian rhythms and the authors are unclear why midday light therapy worked for these patients with bipolar disorder. They plan to investigate further. If it is working via the same mechanism i.e. by resetting circadian rhythms, then it may well work at this time for other individuals too.

It may also be that your depression (and/or anxiety) is not caused by low serotonin but by something else instead – such as low catecholamines, poor thyroid health, gluten issues, poor diet and so on.

Using light therapy and tryptophan (or 5-HTP)

I have also found that some people do well on a combination of light therapy and tryptophan (or 5-HTP). One of my clients had many low serotonin symptoms and did better mood-wise and with reduced anxiety, on a small amount of tryptophan but still needed additional serotonin support. Additional tryptophan was too much for him and increased his day-time sleepiness, but using a small amount of tryptophan together with light therapy was the ideal balance for him.

Have you used light therapy with success – for the winter blues or depression or bipolar disorder? Or even for anxiety?

Have you ever used it at midday or at other times?

And have you used light therapy in conjunction with tryptophan or 5-HTP?

Integrative Medicine for Mental Health Conference 2017 (IMMH)

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The Integrative Medicine for Mental Health Conference 2017 (IMMH) runs Sept 28-Oct 1, 2017, in Orange County, CA (near Anaheim).

This is a conference I attend every year and I’ll be attending again this year – it’s that good! As IMMH mentions:

research has revealed that many disorders such as depression, bipolar disorder, anxiety, OCD, eating disorders, and autism spectrum disorders often have biomedical causes that contribute to symptoms, from nutritional deficiencies to chronic infections.

This is a practitioner-only event and attendees include psychiatrists, naturopathic physicians, family physicians, chiropractic physicians, nurses and nurse practitioners, psychologists, nutritionists and registered dieticians, and other allied mental health professionals. 

Here is a video with highlights from the 2016 conference

Here are just a few of the topics and speakers I am especially looking forwarding at the 2017 conference:

Integrative Medicine Approaches to Autoimmune Encephalopathy and PANDAS – KENNETH BOCK, MD

This lecture will discuss neuropsychiatric disorders with abrupt onset that include symptoms ranging from anxiety to intrusive thoughts and rage episodes. They may also include tics, dysgraphia (inability to write coherently), and dyscalculia (difficulty understanding numbers). These symptoms are triggered by infectious autoimmune encephalopathy (frequently referred to as PANS/PANDAS). Evaluation and treatment will be discussed from a comprehensive integrative medicine point of view.

Ion Channel Genetics in Mental Health: Associated Integrative Therapies – LAUREN FEW, PHD

Several studies have implicated genetic mutations in voltage-gated ion channels in the pathogenesis of mental health disorders. For example, both the CACNA1C calcium channel gene and ANK3 gene have been linked to bipolar disorder, schizophrenia, and depression in genome-wide association studies. This talk will focus on a number of integrative therapeutic options that target ion channels and have demonstrated efficacy in the treatment of mental health symptomatology, including omega-3 fatty acids, lithium, magnesium, and N-acetylcysteine.

Mold and Mycotoxins: The Hidden Menace – MARK FILIDEI, DO

Mold and fungi are ubiquitous in the environment. However, particularly in “WDB”, water damaged buildings, mold can become a sinister force affecting physical and mental health. Not all molds are toxic and many just cause respiratory issues, but a subset of molds produce mycotoxins; powerful neurotoxins that can have a profound effect on the brain and mental health. The effects of mold, as well as testing, diagnosis, and treatment options will be discussed.

Mitochondria and Mood: Understanding the Role of Mitochondrial Dysfunction in Psychiatric Illness – PETER BONGIORNO, ND

As the ‘powerhouse of the cell’ and nervous system, healthy mitochondrial function is an underlying key to healing mental illness. Dr. Bongiorno will explain what you need to know to help identify mitochondrial issues, understand the factors that contribute to poor function, and review the best natural treatments to restore mitochondrial health.

Helping Patients Follow Special Diets Despite Barriers – JULIE MATTHEWS, CNC

How do we support effective special diet implementation when our patients – both adults and children – face varied behavior, psychosocial, and environmental barriers? How do you determine the right diet for each individual? If it’s too complex or restrictive the patient may become overwhelmed and non-compliant. If it’s too basic, you may not see positive results. In this presentation, Julie will share keen insights gleaned from fifteen years of working with special diets for complex digestive, immune, and neurological conditions in both children and adults, audiences fraught with implementation challenges.

Discovery of a Novel Cause of Alzheimer’s Disease – DALE BREDESEN, MD

The cause(s) of Alzheimer’s disease have remained incompletely defined, although risk factors such as type 2 diabetes and the epsilon-4 allele of the Apolipoprotein E gene (ApoE4) have been described. Precision medicine approaches have proven valuable for the evaluation and treatment of various malignancies. This presentation will review the metabolic profiling done by Dr. Bredesen and his team in patients with Alzheimer’s disease and pre-dementia conditions. The results suggested that mycotoxin exposure may be a novel cause of Alzheimer’s disease.

Genetic SNP Testing for Neuropsychiatric Disorders – WILLIAM SHAW, PHD

Genetic variants called single nucleotide polymorphisms (SNPs) play a greater role in the metabolism of the human brain compared to almost all the other organs. A SNP called apolipoprotein E4 markedly increases the chance of developing Alzheimer’s disease after 50. A SNP in protein HFe that absorbs iron improves brain function in populations that have dietary iron deficiency but greatly increases the risk of psychiatric disease in populations in which dietary iron is excessive. In this presentation, a survey of the most significant SNPs for psychiatric diseases and potential “fixes” for these SNPs will be reviewed.

Estrogen and Mental Health: Exploring Estrogen’s Vital Role Linking the Brain, the Gut Microbiome, and the Immune System – FELICE GERSH, MD

There is an amazing and complex interrelationship involving our gut microbiome, our brain function and emotional wellbeing, and our hormones, and most particularly estrogen. A dialogue has only recently been re-initiated, opening the door to a deeper exploration of the most advantageous ways and manner in which to deliver estrogen supplementation for the improvement and prevention of cognitive and mood disorders. This talk will review how this dialogue is unfolding and using this new information, provide practical ways to address mental health issues.

Botanicals for Depression: Rhodiola, St. John’s Wort, Curcumin and Saffron – JUDITH PENTZ, MD

Botanicals have long been a part of the healing traditions in many cultures for depression. Certain medicinal herbs have increasing evidence based research and thus can be part of toolbox for an integrative medical practice. Yet, having a greater understanding of the complexities that herbs present is critical in having a successful outcome when prescribing them for your patients.

Here is the entire schedule and all the topic outlines

And here is the link to register

This is a practitioner-only event and CEs and CMEs are available.

Hope to see you there! I’m not presenting again this year (as you saw in the video I did present last year) but will be there to support my dear friend and colleague Julie Matthews AND will also have a booth there to share The Antianxiety Food Solution message!

If there is enough interest I’m going to arrange a small group meet-up with Julie and I and some of the speakers so please let me know in the comments below if this is of interest.

P.S. If you are NOT a practitioner and are interested please pass this on to your doctor, nutritionist, social worker, therapist, naturopath etc. The event is also recorded and will be available to purchase after wards so please leave me a note in the comments if you’re interested in the recordings.

Time magazine: ketamine is NOT the solution for treatment resistant depression!

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Seen at LAX airport en route back to Australia – this cover of Time magazine:

The Anti Antidepressant. Depression affects 16 million Americans. One third don’t respond to treatment. A surprising new drug may change that.

It’s scary to think that ketamine and ketamine-like drugs are being considered the solution to “treatment resistant depression”. I’ve never liked this term and in my opinion, what it really means is that the root cause of the depression has not been found. To me it looks like the mainstream medical mental health community is desperate!

It really is time to get all the well-researched nutritional psychiatry approaches to the forefront! They do work! The timing of this article is even more interesting since I was returning from the first international meeting of the International Society for Nutritional Psychiatry Research in Bethesda, MD.

Lead food mood researcher Professor Felice Jacka presented her SMILES paper where dietary changes from a junk food diet to a real whole foods diet reduced depression in 30% of the participants.

Microbiome researcher Professor John Cryan discussed the gut brain connection. This paper: Recent developments in understanding the role of the gut microbiota in brain health and disease, was published just last week:

recent preclinical and clinical evidence suggest that targeting the microbiota through prebiotic, probiotic, or dietary interventions may be an effective “psychobiotic” strategy for treating symptoms in mood, neurodevelopmental disorders, and neurodegenerative diseases

And research on sulforaphane for psychosis, and depression and anxiety was presented: Sulforaphane produces antidepressant- and anxiolytic-like effects in adult mice

these findings demonstrated that SFN [sulforaphane] has antidepressant- and anxiolytic-like activities in stressed mice model of depression, which likely occurs by inhibiting the hypothalamic-pituitary-adrenal (HPA) axis and inflammatory response to stress. These data support further exploration for developing SFN [sulforaphane] as a novel agent to treat depression and anxiety disorders.

I presented on the benefits of a gluten-free/grain free/Paleo diet for certain individuals for depression and anxiety, and did a poster presentation on GABA for eliminating anxiety. 

As you can see from the TIME Magazine article the only approaches that have been considered (and have failed) are medications in various different combinations:

Every week, when Ian Hanley sits down with his therapist, he goes through a list of depression treatments he’s been researching online. The best-known treatments at the top of the list–half a dozen antidepressants and known combinations of those drugs–are all crossed out….

Most diagnoses do not come with 20-plus medicines approved by the Food and Drug Administration to treat it–and yet with depression, more options don’t always mean better outcomes. Ever since the first antidepressants were introduced 60 years ago, doctors have had patients like Hanley–people who don’t seem to get better even after they’ve worked their way through the lengthy list of available drugs. About 30% of all people with depression don’t respond adequately to the available treatments. That’s a dismal failure rate for a class of drugs designed to improve a person’s basic ability to function.

According to this article in Time magazine:

The biggest development has been the rediscovery of a promising, yet fraught, drug called ketamine. It’s best known as a psychedelic club drug that makes people hallucinate, but it may also have the ability to ease depression–and fast. In a race to shape the next generation of antidepressants, Johnson & Johnson and Allergan are fast-tracking new medicines inspired by ketamine.

I encourage you to read the entire article and take note of the following: the side-effects seen with medications over the years and the fact that doctors “don’t know the consequences and potential side effects of taking tiny doses of ketamine over and over again”; “she tried nearly everything” (you’ll read this in all the articles advocating for ketamine but unfortunately they are only referring to medications); the ketamine effects are temporary and cost $15,000 per year (and are not covered by insurance); and ketamine “is thought to stimulate an opioid receptor in the brain” and is already known to be addictive.  

When I shared this image and article on my Facebook page I discovered that is a pretty divided topic with a number of people feeling really strongly about the fact that this approach needs to be researched further and considered.  I acknowledge their concern for the individuals who have not found a solution for their depression. BUT my question is this: have all the dietary and nutritional approaches been considered and looked into with these people who have not responded to antidepressants? 

I strongly believe that ketamine is NOT the solution and that nutritional psychiatry is!

Have you used this ketamine approach personally or with patients?

Would you consider using ketamine personally if the antidepressants didn’t work for you? Or would you be more willing to work with a functional medicine or functional nutrition practitioner to find your true root causes and address them with diet, nutrients and a functional medicine approach?

Depression as a black dog that comes in and lays down beside you at night

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Trevor King’s interview about his journey with depression – on That Vitamin Summit – is not to be missed if you are depressed, have ever suffered with depression or if you have a loved one or friend with depression. He shares how he feels a sense of complete hopelessness at times:

It descends like a black cloud that makes me almost sort of retreat into myself. And my eyes will know and I don’t want to take the world in. I don’t want to get out of bed at times. Actually, that’s one of the things that … one of the only things that actually helps me, is going to bed and lying down.

Winston Churchill famously described it as this black dog who’d come in and lay beside him at night.

“From the moment my eyes opened in the morning, I am engaged in a battle. I must protect myself with armor against ongoing, negative, intrusive thoughts that flood into my brain, while sending my prefrontal cortex, which is the home of logical thought, the green light to make decisions and take charge of my brain’s limbic system. That is, before the fear center completely spazzes out. I spend more time and energy chasing and maintaining good health than I do in any other aspect of my life. My marriage, family or work. Because I know that everything meaningful and good around me depends on a stable base. And I hope and pray that one day, I don’t have to fight so hard for my sanity.”

He talks about how he is affected by sugar and low blood sugar, and how he’s found some benefits with niacin, chromium, magnesium and tryptophan (when he’s consistent with taking them!).

Trevor actually talks about the GABA interview I did with him a few days earlier and how he’s very interested in what he learned. He is planning to do a trial of GABA to see if it can help him further.

Here is a snippet from my interview on GABA (so do tune in to this interview if you’re new to my work and the targeted amino acids):

GABA is really quite profound. When I had my anxiety, GABA was my lifesaver. It completely turned my life around. Within three days of using GABA, the panic attacks stopped and the anxiety started to go down, and then I had to look for all the other root causes. It worked immediately so I’m a complete believer, just because I’ve experienced it myself. You’ll hear a lot of people say GABA won’t work. It doesn’t cross the blood/brain barrier so it’s not going to have an impact.

We’ve now got research showing that there may be ways that it crosses the blood/brain barrier. We’ve also got research showing that we have GABA receptors in various parts of our body. We’ve got a lot in our muscles, and with low GABA symptoms you’ll have physical tension.

The beautiful thing is it works. It works quickly, and if you have these low GABA symptoms, which is the physical anxiety, which could be panic attacks. It could be stress eating, it could be drinking to calm down. If you are the kind of person who needs wine to wind down at the end of the day, that’s a big sign that you may need GABA. You take the GABA and you just feel this physical tension release from you, you know you’re onto something good.

I just wish I’d known about his struggles with depression at the time of our interview – I would have talked more about tyrosine for dopamine support (for curl up in bed depression) and DPA for endorphin boosting (for low endorphins weepy depression). 

I did discuss gluten and would consider this especially since his daughter has issues with it. I talked about low serotonin and mentioned Lidtke tryptophan.  If someone doesn’t do well on another brand I’d have them trial the Lidtke brand.  I’d also look into SIBO – I have SIBO and rice and grains make me feel flat and low and I see this often with clients.  Finally I’d look into lithium orotate for keeping an even mood. 

Trevor shares these wise words at the end of his interview:

You do find that when you actually bite the bullet and share it with people,

people are very, very understanding. And actually, you’re amazed that many people have been there themselves.

I could not agree more which is why I’ve always shared my journey with anxiety. I appreciate him for being willing to share his story with depression!

If you’re not already registered here is the registration link for That Vitamin Summit

Feel free to post questions or feedback below – and share your story with anxiety or depression if you feel drawn to do so