multiple sclerosis

Multiple sclerosis: low endorphin research and the amino acid DPA (d-phenylalanine) for pain, depression, comfort and trauma support

April 28, 2023 By Trudy Scott 8 Comments

The research on the role of low endorphins in multiple sclerosis (MS) is exciting because it creates more awareness about a powerful way to offer pain and mood support if you have been diagnosed with this condition. Typically, I ignore the diagnosis when assessing for low levels of neurotransmitters (via a symptoms questionnaire) and have clients do a trial of the amino acid DPA (d-phenylalanine) if they have physical pain symptoms, experience emotional pain symptoms with excessive weepiness/crying and seek comfort via treats/rewarding foods or the numbing effects of alcohol. However, we now know low endorphins play a role in MS (via the endogenous opioid system). By addressing low levels with DPA, you can find some relief of the above pain/depression symptoms and a need for comfort and numbing. DPA may also offer some trauma support if past trauma is a contributing factor (more on all of this below).

Low endorphins play a role in multiple sclerosis: the research

This 2021 paper, Multiple Sclerosis and the Endogenous Opioid System describes MS and the fact that current therapies have limited efficacy: “Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation, neuronal degeneration and demyelinating lesions within the central nervous system. The mechanisms that underlie the pathogenesis and progression of MS are not fully known and current therapies have limited efficacy.”

What is exciting is the identification of the role of the endogenous opioid system and specific opioid peptides in MS:

Preclinical investigations using the murine experimental autoimmune encephalomyelitis (EAE) model of MS, as well as clinical observations in patients with MS, provide converging lines of evidence implicating the endogenous opioid system in the pathogenesis of this disease.

In recent years, it has become increasingly clear that endogenous opioid peptides, binding μ- (MOR), κ- (KOR) and δ-opioid receptors (DOR), function as immunomodulatory molecules within both the immune and nervous systems.

The endogenous opioid system is also well known to play a role in the development of chronic pain and negative affect [i.e. depression], both of which are common comorbidities in MS. As such, dysregulation of the opioid system may be a mechanism that contributes to the pathogenesis of MS and associated symptoms.

Endogenous means internal i.e natural compounds produced by the body and involved in pain relief and mood improvement. This article, Opioid Peptides, describes peptides as compounds that “produce the same effects as the chemicals known as classic alkaloid opiates, which include morphine and heroin.”

It also mentions three major categories of opioid receptors – mu, delta, and kappa – referred to as MOR, DOR and KOR above.

D-phenylalanine for human “endorphin deficiency diseases”

Unfortunately neither of these papers mentions the amino acid DPA (d-phenylalanine) and the fact that it supports endorphin production (by inhibiting the breakdown of endorphins), reducing pain and improving mood – quickly (as in 5-10 minutes).

The use of DPA is not new information as you can read in this paper from 1982 – D-phenylalanine and other enkephalinase inhibitors as pharmacological agents: implications for some important therapeutic application

A number of compounds have been shown to inhibit the degradation of enkephalins. As expected, these compounds produce naloxone reversible analgesia and potentiate the analgesia produced by enkephalins and by acupuncture.

One of these, D-phenylalanine, is also anti-inflammatory.

D-phenylalanine has proven to be beneficial in many human patients with chronic, intractable pain. It is proposed the enkephalinase inhibitors may be effective in a number of human “endorphin deficiency diseases” such as depression, schizophrenia, convulsive disorders and arthritis.

Such compounds may alleviate other conditions associated with decreased endorphin levels such as opiate withdrawal symptoms.

Prevalence of anxiety/depression and alcohol abuse in MS

As I shared in the recent post addressing low GABA symptoms (anxiety, muscle stiffness, swallowing/voice issues and pain) in multiple sclerosis, anxiety and depression is common in this condition. Alcohol abuse is also high. I shared this paper, The incidence and prevalence of psychiatric disorders in multiple sclerosis: A systematic Review, with the following results:

Among population-based studies, the prevalence of anxiety was 21.9% (and up to 35.0% in some papers), 23.7% for depression …and 14.8% for alcohol abuse.

The above Opioid Peptides paper highlights that the endogenous opioid system may be related to excessive alcohol-drinking behavior. In the work I do with amino acids, I see alcohol used as a way to numb out.

All this supports the fact that the amino acid DPA may help ease symptoms of depression and weepiness seen in MS, and self-medicating with alcohol.

The goal is to use these amino acids instead of needing to use benzodiazepines (covered in the above GABA blog), antidepressants and pain medications.

DPA may help trauma in MS, and the freeze response

This paper, Childhood Trauma in Multiple Sclerosis: A Case-Control Study, suggests an association between childhood trauma and early-life stress and MS:

Although childhood trauma was not associated with the degree of current MS-related disability, patients with MS with histories of physical and/or sexual abuse had significantly higher relapse rates than patients without early-life stress.

DPA may also offer some trauma support if past trauma is a contributing factor. I learned about trauma and the low energy freeze state (a survival mechanism) from Dr. Aimie Apigian, MD, MS, MPH. There is the feeling of numbness and being disconnected when in the freeze state and this eventually becomes the default pattern that the nervous system has been wired into.

Individuals with low endorphins are often in the freeze state and are more emotionally sensitive to everything and because of this they experience much more stress. They also experience a feeling of numbness and feel disconnected. The encouraging news is that the amino acid DPA helps ease the low endorphin symptoms while they are addressing their trauma in other ways, like with somatic work and addressing other biological underpinnings of trauma.

DPA is comforting, helps you feel safe and is often described as feeling like someone just hugged you.

Endorphins and the amino acid DPA (d-phenylalanine) and DLPA (dl-phenylalanine)

If you’re new to endorphins and the amino acid DPA and DLPA here are some blog posts:

Low GABA and low serotonin are common in multiple sclerosis too

Low endorphins are just the tip of the iceberg when it comes to the underlying neurotransmitter imbalances in MS. Low GABA and low serotonin are common too.

As mentioned, I recently blogged about the GABA research and applications of GABA when it comes to multiple sclerosis. Here is that link.

When that blog was published I had a number of questions (see the comments in the above link) from folks asking if GABA could help with similar symptoms in Parkinson’s: swallowing and voice problems, pain and hand spasms. I said yes – if GABA is low, the amino acid GABA will help. As important as your diagnosis is, it’s always the questionnaire/symptoms that help you figure out if it’s worth trialing GABA, DPA or one of the other amino acids.

Both GABA and DPA can help pain symptoms via different mechanisms, so it’s a matter of doing a trial of each amino acid, one at a time and monitoring your response.

Tryptophan and/or 5-HTP may help ease some of the low serotonin worry-type of anxiety, fear, panic attacks, obsessing, low mood and MS-specific pain issues and insomnia.

If you do have more than one imbalance (which is not unusual), you need to figure out which imbalance you have and address that with the relevant amino acids, one at a time. I have clients pick the area that is more problematic for them and start there.

I gathered some of this research while preparing for an interview with the wonderful Dr. Terry Wahls, MD and author of “The Wahls Protocol.” We were both pleasantly surprised to see these endorphin/MS and other neurotransmitter connections.

I really look forward to seeing future research on the use of the amino acids DPA, GABA and tryptophan in MS. And I’d love to be involved in some studies if you are associated with a research facility or do research.

Resources if you are new to using amino acids as supplements

If you are new to using amino acids as supplements, here is the Amino Acids Mood Questionnaire from The Antianxiety Food Solution (you can see all the symptoms of neurotransmitter imbalances, including low GABA, low serotonin and low endorphins).

If you suspect low levels of any of the neurotransmitters and do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the practitioner/health team you or your loved one is working with.

There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, gluten, blood sugar control, sugar cravings, anxiety and mood issues.

The book doesn’t include product names (per the publisher’s request) so this blog, The Antianxiety Food Solution Amino Acid and Pyroluria Supplements, lists the amino acids that I use with my individual clients and those in my group programs. You can find them all in my online store.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA QuickStart Program (if you have low GABA symptoms too). This is a paid online/virtual group program where you get my guidance and community support.

If you are a practitioner, join us in The Balancing Neurotransmitters: the Fundamentals program. This is also a paid online/virtual program with an opportunity to interact with me and other practitioners who are also using the amino acids.

Do you have multiple sclerosis and has the amino acid DPA helped with your low endorphin symptoms: pain, depression, alcohol addiction, comfort and trauma support?

How much has helped and which product do you use?

Do you find opening a capsule of DPA helps more than swallowing the DPA capsule?

Were you surprised that DPA would help so much?

What else has helped your multiple sclerosis symptoms? And have you also addressed low GABA and serotonin with amino acids GABA and tryptophan?

If you have questions and other feedback please share it here too.

Multiple sclerosis: low GABA research and the amino acid GABA for anxiety, muscle stiffness, swallowing/voice issues and pain

April 14, 2023 By Trudy Scott 12 Comments

I’m excited about the GABA research – an older paper and some new studies – on multiple sclerosis (MS). This means there is the potential for using GABA supplementation in similar ways it’s used with other conditions where anxiety, insomnia and pain are issues. This can include the typical low GABA-type physical anxiety, stiff and tense muscles, insomnia and pain, and also MS-specific issues such as spasticity, laryngospasms, balance issues, swallowing and speaking/voice issues and sensorimotor problems.

Anxiety is common in MS and benzodiazepines are commonly prescribed. The ideal is to use the amino acid that supports GABA, instead of needing to use benzodiazepines. I share some of the GABA/MS research and specific applications for using GABA below.

Prevalence of anxiety/depression in MS and the use of benzodiazepines

Anxiety and depression is common in multiple sclerosis. This paper, The incidence and prevalence of psychiatric disorders in multiple sclerosis: A systematic Review, included 118 studies and found that:

Among population-based studies, the prevalence of anxiety was 21.9% (and up to 35.0% in some papers), 23.7% for depression, 14.8% for alcohol abuse, 5.83% for bipolar disorder, 4.3% for psychosis and 2.5% for substance abuse.

psychiatric comorbidity remains understudied.

What is concerning is that benzodiazepines such as Ativan, Valium and Xanax are commonly prescribed for MS patients for their anxiety, insomnia, spasticity and pain. Recent research, Use of Benzodiazepines and Z-Drugs in Multiple Sclerosis found that benzodiazepine use is more “more common in people with MS than in general population controls, and use of these agents is in persons with MS is often chronic” i.e. for longer than 6 months.

This is problematic given that anything over 2 weeks can cause dependence, tolerance and withdrawal. They can cause balance issues and can actually cause anxiety and insomnia. Someone in my community was totally disabled for over 3 years with “locked shoulder muscles, neck, jaw …internal vibrations… bad headaches, jelly legs, distorted vision like floaters and squiggles and fireworks …cortisol rushes through the body.. And tortured every day.” Read more about her horror story and benzos here.

The ideal is to use the amino acid that supports GABA, instead of needing to use benzodiazepines.

Low GABA plays a role in multiple sclerosis: the research

Low GABA (gamma-aminobutyric acid) plays a role in multiple sclerosis. This paper, Reduced gamma-aminobutyric acid concentration is associated with physical disability in progressive multiple sclerosis states that there are

reduced GABA levels in the hippocampus and sensorimotor cortex of patients, and show that reduced GABA in the sensorimotor cortex is associated with increased motor impairment. Changes in GABA may be a marker of neurodegeneration.

This study supports the idea that modulation of gamma-aminobutyric acid neurotransmission may be an important target for neuroprotection in multiple sclerosis.

Of course, the authors don’t mention using the calming amino acid GABA, but we extrapolate and use what we see clinically in other conditions like autism (more on that below).

Two other papers support the GABA connections. This 2021 paper, Altered Plasma Metabolic Profiles in Chinese Patients With Multiple Sclerosis, observed “a great increase in the levels of L-glutamic acid” in patients with MS. Increased glutamate typically means low GABA levels.

Guanidinoacetic acid (GAA) is an experimental nutrient that is new to me, but the GABA effects and mechanisms are encouraging. In this 2022 paper, Guanidinoacetic Acid as a Nutritional Adjuvant to Multiple Sclerosis Therapy the author states that GAA may benefit MS patients via “modulation of gamma-aminobutyric acid (GABA)ergic neurotransmission and brain oxidant-antioxidant status, or a reduction of glutamate neurotoxicity.’

The author also shares that “demyelination is often characterized by various neurochemical abnormalities in GABA-glutamate metabolism.”

In case you’re new to MS and demyelination, this Mayo Clinic article describes them as follows:

A demyelinating disease is any condition that causes damage to the protective covering (myelin sheath) that surrounds nerve fibers in your brain, the nerves leading to the eyes (optic nerves) and spinal cord. When the myelin sheath is damaged, nerve impulses slow or even stop, causing neurological problems.

Multiple sclerosis is the most common demyelinating disease of the central nervous system. In this disorder, your immune system attacks the myelin sheath or the cells that produce and maintain it.

This attack causes inflammation and injury to the nerve sheath and ultimately to the nerve fibers that it surrounds. The process can result in multiple areas of scarring (sclerosis).

Using GABA for easing anxiety, overwhelm and insomnia in multiple sclerosis

There is no research that I am aware of that has studied the use of GABA supplementation in MS. We can, however, extrapolate from other conditions and use GABA for easing various MS symptoms based on what we see clinically.

As mentioned above, anxiety is common in MS and if you have the low GABA type of physical anxiety, GABA is worth a trial for easing typical low GABA symptoms of physical anxiety, feelings of overwhelm and intrusive thoughts, stress eating, using alcohol to relax or fit in socially and insomnia. You can read more about GABA for physical anxiety here and see all the low GABA symptoms here.

And here are a few examples/case studies:

Using GABA to help with balance, and sensorimotor and coordination issues in multiple sclerosis

These case studies illustrate an application for GABA being used for balance, sensorimotor and coordination issues that are common in MS (they are not folks with MS):

Much of the research in this area has been done with autism, as illustrated by this GABA Oolong tea study tea in children with autism. They saw improvements in sensorimotor skills, autism profiles, anxiety and sleep.

Using GABA to help with stiff and tense muscles, spasticity, voice issues, laryngospasms and difficulty swallowing in multiple sclerosis

GABA helps to ease stiff and tense muscles in those with physical anxiety. In a similar way we see GABA help with these common MS symptoms: muscle spasms, spasticity, voice issues, laryngospasms and swallowing difficulties (dysphagia affects about a third of folks with MS).

These case studies illustrate an application for GABA being used for some of above issues that are common in MS (they are not folks with MS):

Again, there is no research that I am aware of specifically with MS, but clinically I see GABA helping all of the above symptoms related to spasms and muscle tension, often with anxiety and pain as an underlying factor too.

Other MS symptoms that may also be supported by addressing low GABA levels: bowel issues and rectal spasms, bladder issues/spasms, tremor and problems with memory/thinking, and possibly even vision issues.

I really look forward to seeing future research on the use of the amino acid GABA in MS. And I’d love to be involved in some studies if you are associated with a research facility or do research.

Low serotonin and low endorphins are common in multiple sclerosis too

Low GABA is just the tip of the iceberg when it comes to the underlying neurotransmitter imbalances in MS.

The amino acid DPA/d-phenylalanine may help ease some of the low endorphin pain symptoms, weepy kind of depression, and alcohol addiction. You can read about this here.

Tryptophan and/or 5-HTP may help ease some of the low serotonin worry-type of anxiety, fear, panic attacks, obsessing, low mood and MS-specific pain issues and insomnia. I’ll write more about this and the supporting research in a follow-up blog.

Resources if you are new to using GABA and the other amino acids as supplements

If you are new to using GABA and the other amino acids as supplements, here is the Amino Acids Mood Questionnaire from The Antianxiety Food Solution (you can see all the symptoms of neurotransmitter imbalances, including low GABA, low serotonin and low endorphins).

There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, gluten, blood sugar control, sugar cravings, anxiety and mood issues.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA QuickStart Program (if you have low GABA symptoms). This is a paid online/virtual group program where you get my guidance and community support.

Do you have multiple sclerosis and has the amino acid GABA helped with your anxiety and fears; muscle stiffness and spasticity; swallowing, laryngospasms and voice problems; balance and sensorimotor issues, insomnia and pain?)

How much has helped and which product do you use?

Do you find sublingual, powder or an opened capsule helps more than swallowing the GABA capsule?

Were you surprised that GABA would help so much?

What else has helped your multiple sclerosis symptoms? And have you also addressed low serotonin and low endorphins with amino acids tryptophan and DPA?

If you have questions and other feedback please share it here too.

Research opportunity: Parkinson’s disease and Multiple Sclerosis – participate in diet research

January 13, 2017 By Trudy Scott 4 Comments

We know that anxiety is very common in both Multiple Sclerosis/MS and Parkinson’s disease so I’m sharing this diet research opportunity in case you or someone you know can benefit.

Dr. Terry Wahls, author of The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles (and past speaker on the Anxiety Summit) shared this diet research opportunity via her newsletter: Dr. Laurie Mischley, ND is recruiting patients for this world-wide research opportunity i.e. you can live anywhere.

Dr. Mischley was so impressed with what she had observed [in her MS diet research] that she added the Wahls Diet as one of the dietary variables to her ongoing Parkinson’s study. If any of you have family or friends with Parkinson’s or MS, please encourage them to participate in one of these studies. Dr. Mischley’s studies are unique. Her team at Bastyr University is studying patients with chronic disease and assessing several variables to see if there is a common theme among those who had the best outcomes and the slowest disease progression.

The effort is minimal–you can participate from anywhere in the world by simply completing online surveys. The surveys are given every six months and include questions about medications, diet, herbal supplements, exercise, meditation, and an array of other factors.

This information will give Dr. Mischley’s team an ever-growing data set to analyze, searching for common traits among those who have the best health and function despite having Parkinson’s or MS. Your participation would be a tremendous gift to society because it would help us better understand the impact of dietary and lifestyle factors on health outcomes and functional status for those with Parkinson’s disease or MS.

We are seeing so much promising research on diet and mental health so it makes total sense to be looking at diet for Parkinson’s and MS. Here is some of the research on diet and mental health: anxiety and hypoglycemia and the Western diet and anxiety.

Without published research, clinical practice won’t change. With published research, more clinicians will be willing to utilize diet and lifestyle therapy, restoring health to more patients around the world.

Here is the link for more on the MS study and more on the Parkinson’s study.

The Anxiety Summit: wise words on MS, oxytocin, red meat, marijuana, mercury

June 10, 2016 By Trudy Scott 10 Comments

We’re in the midst of season 4 of The Anxiety Summit www.theanxietysummit.com and here are wise words of wisdom from some of our amazing speakers on MS, oxytocin, red meat, marijuana, mercury and more.

If you have joined the summit and are loving it, this serves as a nice recap, a reminder if you missed a talk and inspiration to stay tuned in for some of the later interviews. And making sure you know that each speaker has a blog with snippets and many additional resources.

And if you’ve recently joined my community for the summit a VERY big welcome!

If you have not yet signed up I hope these wise words inspire you to join us!

Here are some snippets from some of the interviews.

Multiple sclerosis and anxiety: The Wahls Protocol

Dr. Terry Wahls shares how her MS was a gift:

And it all needs to happen this way Trudy. I had to get that disabled. I had to be on the verge of utter catastrophe to begin to feel the effects of cognitive decline to do all this work and then feel the effects of all this healing that happens when you provide a healthy habitat for the human ecosystem and all this repair happens. If this hadn’t of have happened I’d still be a conventional medicine doc thinking the latest drugs out of the New England Journal of Medicine were the way to go as opposed to seeing the gospel of food and sleep and movement and stress reduction.

The Link Between Low Cholesterol and Low Oxytocin

The Pitocin/synthetic discussion oxytocin with Dr. Kurt Woeller was fascinating:

And there’s a theory … that the Pitocin, which is synthetic oxytocin, which is given to women who are not naturally going into labor, it’s meant to action speed labor up. Pitocin being synthetic oxytocin may short circuit in some susceptible kids the natural production of oxytocin, therefore slowing down or turning off those areas in the brain that are normally being developed at that time, with regards to socialization.

Gluten and anxiety: the testing conundrum solution

Dr. Tom O’Bryan’s explanation of the limited gluten sensitivity testing that most people have done:

what happens when people have one of those peptides that the immune system is fighting that’s not the 33 [alpha-gliadin] and you do a blood test for gluten sensitivity. If your doctor orders the common blood test for gluten sensitivity and it looks for alpha-gliadin and it comes back negative and your doctors says you’re fine eating wheat. See, here’s the blood test. Well you can get a false negative meaning it says there’s no problem when there really is because your body’s fighting other peptides of wheat.

Nutrients that Fuel Brain Power and Reduce Anxiety

Dr. Drew Ramsey talks about zinc and animal protein:

Zinc is a mineral and minerals tend to be more absorbable in animal forms. I think a lot of people are very confused about meat and seafood and often intimidated and scared. And then we’ve had this message to go plant based and even vegan which is not a diet that is healthy for the brain.

Dr. Hyla Cass, integrative psychiatrist covers marijuana and anxiety later in the summit:

very often people who have been smoking marijuana for a while – when they go off it they go through serious withdrawal – anxiety, insomnia, feeling really very bad. Very much like we see in movies – we understand what it’s like getting off heroin when people go through withdrawal. Very similar, it really looks similar in appearance. Not everyone does that but common enough.

Dr. John Dempster, co-host of the Mental Wellness Summit discusses mercury as a neurotoxin in his interview later in the summit

So I kind of want to shed some light on some of these areas and how it can affect anxiety directly. One of the big areas is mercury itself is a neurotoxin. So how does that impact our biochemistry and our physiology? Well what it’s going to do it’s going to start to disrupt on an endocrine and a neurotransmitter level some of our pathways. And one of the big pathways is actually the glutamate connection and the glutamate pathway. And glutamate is something that’s known as an excitatory neurotransmitter and this is something that if we have too much of it or it’s not being reuptake properly in our synapses we start to exhibit different types of symptoms of anxiety. And of course that’s just one possible trigger for anxiety.

You can see a list of all the speakers and topics here on the master speaker blog.

You can sign up here: season 4 of The Anxiety Summit www.theanxietysummit.com

If you missed any, not to worry, we’ve decided to do an encore day with ALL the speakers. We don’t want you feeling stressed or anxious about missing out – not on a summit on anxiety!

The Anxiety Summit – Multiple sclerosis and anxiety: The Wahls Protocol

June 8, 2016 By Trudy Scott 21 Comments

Dr. Terry Wahls, MD, author of The Wahls Protocol, was interviewed on the Anxiety Summit by host of the Anxiety Summit, Trudy Scott, Food Mood Expert and Nutritionist, author of The Antianxiety Food Solution.

Multiple sclerosis and anxiety: The Wahls Protocol

A move to diet and lifestyle research
Recovery from MS with functional medicine and the Wahls Paleo™ diet
MS and anxiety: myelin damage, medications, GABA and glutathione
The Wahls Paleo™ diet
Organ meats and a ketogenic diet

Here are some snippets from our interview:

Here are some gems from our interview, starting with a quick overview of the Wahls diet (which is based on Paleo principles:

My focus is ramping up the vegetables and the target is nine cups because I’m a tall lady, six foot tall. And if you’re a petite female or a very petite man it might be six cups. It should be equally divided between dark green leafy vegetables like spinach, kale. Sulfur containing vegetables, in particular the cabbage, onion and mushroom families because of the medicinal qualities of those three food groups. And then deeply pigmented stuff – carrots, beets, peppers, berries. And I’m really looking for all the colors, particularly blue, black, purple.

Dr Wahls shares how her MS was a gift:

And it all needs to happen this way Trudy. I had to get that disabled. I had to be on the verge of utter catastrophe to begin to feel the effects of cognitive decline to do all this work and then feel the effects of all this healing that happens when you provide a healthy habitat for the human ecosystem and all this repair happens. If this hadn’t of have happened I’d still be a conventional medicine doc thinking the latest drugs out of the New England Journal of Medicine were the way to go as opposed to seeing the gospel of food and sleep and movement and stress reduction.

So my kids still sort of wish I’d never gotten MS and that I was still as vigorous of an athlete as I once was. But Jackie and I are like, you know, it all had to happen this way. And the gifts that I’ve received from it happening this way are really quite profound.

Here is Dr. Wahls’ feedback on benzodiazepines:

very, very strong for addiction potential. And then once you’re on them getting off them is a very complicated process because if you suddenly stop you can have withdrawal problems that can become life threatening. So one has to be very gradual, very slow in the reduction phase. It’s certainly very important, very worth doing. The best bet is to never get on that stuff and to use dietary and lifestyle environmental approaches first.

My blog has plenty of information on benzodiazepines. Here is the most recent one – Benzodiazepines: informed consent? Your support is needed. I encourage you to search the blog for additional information.

Here are some of the studies we discussed in the interview:

A recent study in the Journal of Child neurology included 140 children 5-18 years of age. The paper, Behavioral Symptoms in Pediatric Multiple Sclerosis: Relation to Fatigue and Cognitive Impairment, found that

Although the type of clinical problems varied across participants, attention problems, somatization, and anxiety were found to be most common

In another recent study Anxiety, depression and fatigue at 5-year review following CNS demyelination

Of the 236 cases, 40.2% had clinical anxiety, 16.0% had clinical depression, and 41.3% had clinical fatigue.

Dr. Wahls is the author of The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles

I mentioned that we’ll both be presenting at IMMH/ Integrative Medicine for Mental Health in Washington DC in September.

Missed this interview or can’t listen live? Or want this and the other great interviews for your learning library? Purchase the MP3s or MP3s + transcripts and listen when it suits you.

You can find your purchasing options here.: Anxiety Summit Season 1, Anxiety Summit Season 2, Anxiety Summit Season 3, and Anxiety Summit Season 4.