Gluten and anxiety: the testing conundrum solution
- How gluten damages the gut lining and why gut healing is key for brain health
- Alpha-gliadin and the limitations with current testing
- Cyrex array 3: 10 peptides and 3 types of transglutaminase
- Transglutaminase-6 and the brain on fire
- Cyrex array 5: cerebellum, myelin and other brain antibodies
- Cross-reactive foods: spinach, milk, coffee, chocolate
- Autism: testing kids and their moms
In season 2, Dr. O’Bryan presented on this topic: Gluten’s impact on the inflamed brain: reducing anxiety and depression
- “No human on the planet can digest gluten”
- Terminology and why it’s not called gluten intolerance but sensitivity
- Is gluten sensitivity just a fad and the recent FODMAPs research
- The multitude of diseases and symptoms caused by gluten sensitivity
- Gluten sensitivity as a contributing factor to psychiatric manifestations/anxiety/depression and new 2014 research from Italy
- Suicide rates in kids with celiac disease (even when they quit gluten
- We touched on the conundrum with testing
This interview goes deeper into testing and offers a solution to the conundrum.
Here are some gems from our interview:
The most common peptide from poorly digested wheat is 33 pearls long. It’s called alpha-gliadin, 33 pearls. It’s a big peptide. And 50 percent of people with celiac disease have alpha-gliadin elevated but the others don’t. But wait a minute. We know that celiac disease is a sensitivity to wheat. How come these other people don’t have elevated antibodies to the 33 pearl peptide? It’s because the immune system is fighting other peptides of wheat, not the 33. It might be the 17. It might be the 9. It might be the 11. It might be the 22. There are over 60 different peptides of wheat that have been identified to cause or trigger an immune response, over 60. And every lab in the country is only testing one called alpha-gliadin, the 33 pearl. Now that’s an important one to test but it’s not the only one to test.
So what happens when people have one of those peptides that the immune system is fighting that’s not the 33 and you do a blood test for gluten sensitivity. If your doctor orders the common blood test for gluten sensitivity and it looks for alpha-gliadin and it comes back negative and your doctors says you’re fine eating wheat. See, here’s the blood test. Well you can get a false negative meaning it says there’s no problem when there really is because your body’s fighting other peptides of wheat.
Here are the arrays that Cyrex offers. We covered parts of arrays 3, 4 and 5.
Gluten Summit gifts – register here and get these audio interviews:
- Natasha Campbell-McBride: The Critical Nature of Gut Health and its Impact on Children’s Brains
- David Perlmutter: Eliminating Gluten as the 1st Step in Preventing Brain Conditions.
Here is the link to the Certified Gluten-free Practitioner training we discussed
If you are not already registered for the Anxiety Summit you can get live access to the speakers of the day here: www.theAnxietySummit.com
Missed this interview or can’t listen live? Or want this and the other great interviews for your learning library? Purchase the MP3s or MP3s + transcripts and listen when it suits you.