depression

The best food-mood-nutrient topics of 2017

December 29, 2017 By Trudy Scott Leave a Comment

As we move into 2018, it’s time to recap and share the best of 2017 – from both blog posts and facebook posts. Hopefully these topics have helped you move forward as you address your anxiety symptoms and will help you (and your clients/patients if you’re a practitioner) take even bigger leaps as you move into 2018!

Most popular blog posts

Here are the most popular blog posts of 2017, based on comments and questions. If you have already read one of these and found it interesting at the time of publication, it’s worth a re-read for all the valuable comments/questions and my feedback.

Collagen and gelatin lower serotonin: does this increase your anxiety and depression?

I see everyone raving about gelatin and collagen – and rightly so – they have amazing health benefits. However, no-one is addressing the fact that gelatin is actually used in tryptophan-depletion studies to lower serotonin.

Some people get more anxious and depressed when consuming collagen, some do just fine and some even use it to lower their serotonin. Many need to use it with added tryptophan. I recently made some additional updates to this blog and have more to add so stay tuned for more on this topic.

How much GABA should I use and which GABA product is best?

There is no simple answer! It requires a blog post to provide a good answer because we are all unique, have different needs and these needs can even differ at different times depending on the issue and what is going on in our lives at the moment.

My Kid is Not Crazy and PANS/PANDAS awareness day 2017

PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections) occurs when strep triggers a misdirected immune response results in inflammation on a child’s brain. In turn, the child quickly begins to exhibit life changing symptoms such as OCD, anxiety, tics, personality changes, decline in math and handwriting abilities, sensory sensitivities, restrictive eating, and more.

Anxiety, compulsive thinking, counting behaviors: gluten, tryptophan and inositol

Today I’m going to share my feedback on a question I received on how to approach working with a child with anxiety, compulsive thinking and counting behaviors in the hope it can help you or someone you know (or are working with if you’re a practitioner)

DPA for weepiness, pain and comfort and reward eating

This amino acid is a favorite with so many of my clients because it helps with [weepiness, pain and comfort and reward eating] by boosting your endorphins and when you chew a capsule you feel like you just got a big hug.

How to Beat Anxiety and Resolve Panic Attacks with Targeted Amino Acids: Wellness Mama podcast

I share my wonderful interview with Katie, the “Wellness Mama”. We talk about my favorite topic: How to Beat Anxiety and Resolve Panic Attacks with Targeted Amino Acids, with some extra questions about pregnancy and nursing that I’m not often asked about.

GABA for the physical-tension and stiff-and-tense-muscles type of anxiety

I’m going to review some GABA products for the physical-tension and stiff-and-tense-muscles type of anxiety, and share some additional resources for you….

I share that sublingual is best, do a trial and start low, my favorite GABA products and when it works and when it doesn’t.

Tryptophan for the worry-in-your-head and ruminating type of anxiety

I’m going to review some tryptophan products for the worry-in-your-head and ruminating type of anxiety… Lidtke is the only brand of tryptophan that I recommend simply because I see it work so well and because of quality issues with tryptophan in the past.

I also share when to use tryptophan and when to use GABA, and tryptophan for PMS.

GABA: an amino acid supplement for neurotransmitter support and anxiety relief

I recently attended the first international meeting of International Society for Nutritional Psychiatry Research and was honored and thrilled to present my poster – GABA: an amino acid supplement for neurotransmitter support and anxiety relief Because you were not able to be there, here are the contents of my poster word for word.

How GABA eases agonizing rectal pain and spasms in under 2 minutes

Proctalgia fugax is described as a condition that leads to rectal spasms and sharp fleeting pain in the lower rectum or anus. In some people it can be more than fleeting and is often described as excruciating and agonizing.

I have experienced this awful anal sphincter spasm and pain myself so I want to shine some light on this condition and offer the simplest and most effective solution: oral and sublingual GABA. It works to completely eliminate the pain in 1-2 minutes! And it can also be used to prevent a full-on spasm if you catch it in advance.

Migraines, Anxiety and Antiphospholipid Syndrome: on the Chronic Headache & Migraine Summit

The autoimmune condition called Antiphospholipid Syndrome (APS) is one of many possible contributing factors for both migraines and anxiety.

Cognitive impairment, strokes and livedo reticularis is common.

GABA protects against hypothyroidism caused by fluoride and reduces anxiety

To the best of our knowledge, this is the first study to establish the therapeutic efficacy of GABA as a natural antioxidant in inducing thyroprotection against fluoride-induced toxicity.

GABA for children: ADHD, focus issues, irritability, anxiety and tantrums

My daughter hasn’t been diagnosed with ADHD but has a lot of ADHD qualities. We were having a huge amount of behavior problems as she is getting older (she’s 11). I did some research and went to the health food store and bought a bottle [of GABA Calm]. At this point I was mentally exhausted from all the fighting and drama at home and at school. I was desperate and didn’t want to put her on any hard medication.

She has had amazing behavior at school and at home since giving it to her. She’s almost like different child. GABA has truly changed our life. She’s been taking it for almost 2 months.

Anxiety: when to use GABA and tryptophan and how much to use

When you have anxiety it can be confusing trying to figure out the root cause. I like to start by assessing for low GABA and low serotonin because when you address these with targeted individual amino acids you typically see results right away and feel hopeful (and now have time to look for other root causes like gluten issues, high cortisol, gut issues, dietary changes etc).

But there may still be some confusion about when to use GABA and when to use tryptophan and how much of each of these amino acids to use.

Vulvodynia: oxalates, GABA, tryptophan and physical therapy

I just listened to the webinar talking about oxalates. I was shocked and delighted to hear the mention of the connection between high oxalates and vulvodynia.

Research shows there is serotonin involvement with vulvodynia and SSRIs are often prescribed, as are benzodiazepines. My recommendation is trials of tryptophan and/or GABA.

Seriphos Original Formula is back: the best product for anxiety and insomnia caused by high cortisol

If you have high nighttime cortisol (as measured by an adrenal saliva test) it can cause insomnia and anxiety. Using 1-3 x Seriphos about 1-3 hours before the high cortisol is the best way I know for lowering the high cortisol and providing relief.

The product was reformulated and didn’t work like it used to and then the original formula was brought back.

GABA takes some of the anxiety edge away and now I want to add tryptophan: how do I do this?

I would say this – ask yourself what low GABA anxiety symptoms (this is the physical anxiety) have improved with the GABA and how much (rate each one before – out of 10; and what are they now – out of 10). From your question it sounds like they could improve more – so if we were working together I’d continue to increase GABA before adding something new.

The most popular facebook posts

And here are some of the most popular Facebook posts on TrudyScottAntianxietyFoodSolution (based on comments and shares). Many of these link to other sources like the research or other blogs with additional information. Most of them have a great back and forth discussion on the Facebook post so feel free to join in there.

Canola oil linked to worsened memory and learning ability in Alzheimer’s

Canola oil is one of the most widely consumed vegetable oils in the world, yet surprisingly little is known about its effects on health. Now, a new study published online December 7 in the journal Scientific Reports by researchers at the Lewis Katz School of Medicine at Temple University (LKSOM) associates the consumption of canola oil in the diet with worsened memory, worsened learning ability and weight gain in mice which model Alzheimer’s disease. The study is the first to suggest that canola oil is more harmful than healthful for the brain.

Canola oil is not something I’ve ever recommended and I’m really glad to see this research. You have to read labels because it’s in a lot of salad dressings and processed foods!

Nestle to buy vitamin maker Atrium Innovations for $2.3 billion

The following brands are now owned by Nestle: Garden of Life, Douglas Laboratories, Pure Encapsulations.

This is not good! Other than the fact that the formulations will likely be changed, there is much to be said about Nestle and their ethics.

The Big Vitamin D Mistake

This could lead to a recommendation of 1000 IU for children <1 year on enriched formula and 1500 IU for breastfed children older than 6 months, 3000 IU for children >1 year of age, and around 8000 IU for young adults and thereafter. Actions are urgently needed to protect the global population from vitamin D deficiency.

Do you use a zinc supplement every day?

1) how much and what form? and with or without copper?
2) how did you decide to add zinc (or was it recommended by a practitioner)
3) how did you assess your zinc status (alk phos? zinc challenge/tally? mood symptoms? white flecks on nails? poor digestion? pyroluria questionnaire? blood work? other?)
4) how it helps you? (less anxious? more social? less depressed? less cravings? better digestion? better skin? less aches/pains? better blood sugar control? less PMS/hormone symptoms? better adrenal health? better immunity? other?)

Scary new information about benzodiazepine deaths

The five most frequently occurring drugs found in decedents were ethyl alcohol (5,318), benzodiazepines (5,167, including 1,851 alprazolam occurrences), cocaine (2,882), cannabinoids (2,292), and morphine (2,040).

With teen mental health deteriorating over five years, there’s a likely culprit

In a new paper published in Clinical Psychological Science, my colleagues and I found that the increases in depression, suicide attempts and suicide appeared among teens from every background – more privileged and less privileged, across all races and ethnicities and in every region of the country. All told, our analysis found that the generation of teens I call “iGen” – those born after 1995 – is much more likely to experience mental health issues than their millennial predecessors.

What happened so that so many more teens, in such a short period of time, would feel depressed, attempt suicide and commit suicide? After scouring several large surveys of teens for clues, I found that all of the possibilities traced back to a major change in teens’ lives: the sudden ascendance of the smartphone.

Gabapentin and pregabalin are as problematic as benzodiazepines

Crippling toll of the new valium that’s ruining the lives of MILLIONS

Can you relate to the term high-functioning anxiety?

Busy and in control. High-achieving and perfectionistic. Driven by details and order in a desperate attempt to calm racing thoughts, worry, and the fear that invade every ounce of the mind and body. An over-thinker with a tendency to perseverate, dwell, and stew on everything.

I used to be like this before the panic attacks and it’s a big clue that it’s time to do something about it but too often we push and push and push and then it gets really bad. I would love to be able to reach women (and men) at this stage before it gets really bad!

Great article about squatting and the benefits

How often do you squat? and do you use a device like the Squatty Potty?

Screen time might boost depression, suicide behaviors in teens

A new study finds that teens, especially girls, who spend several hours per day on phones and tablets are more likely to be depressed and have suicide-related outcomes.

When it comes to cravings, addiction and appetite we have this research supporting the use of glutamine

– Glutamine and glutamatergic metabolism is a factor in cravings and alcohol dependence
– A combination of tyrosine, lecithin, glutamine and 5-HTP helped withdrawal syndromes and mental symptoms in detoxified heroin addicts
– Glutamine has been shown to decrease secretion of ghrelin, the hormone that impacts appetite regulation. High levels of ghrelin appear to make high-calorie foods look more appealing.

Why the vaginal mesh scandal could be ‘bigger than thalidomide’

More than 92,000 women had vaginal mesh implants between 2007 and 2015 in England, and about one in 11 is said to have complications. More than 800 of these women are now taking legal action against the NHS and mesh manufacturers.

Please be aware of the dangers of vaginal mesh (and other procedures that use mesh) – it’s something I’ve always warned my clients about and it needs to become common knowledge

Do you take probiotics on a daily basis and do they help? Have you had to stop taking probiotics because of any adverse effects?

Melatonin–estrogen interactions in breast cancer

Individualized protocols in Dr. Nalini Chilkov’s OutSmart Cancer system include melatonin at 10-20mg at bedtime (to match nature’s cycling of melatonin…not for sleep issues) . MANY breast cancer patients have low or aberrant melatonin patterns.

The anti antidepressant. Depression affects 16 million Americans.

One third don’t respond to treatment. A surprising new drug may change that: ketamine.

I’m quite surprised how many women who are smart and savvy when it comes to eating and natural health continue to color their hair (or straighten or perm or treat).

I’m curious if you are one of those people ? And if yes why? Do you know the risks or would you just prefer not to know?

Excellent article on toxic sunscreen ingredients

I have always avoided conventional sunscreens and teach my clients about this but wish more people were aware of these issues. It’s not just sunscreens either…so many skin care products, makeup, hair products and household products have ingredients that are endocrine disrupters, cause DNA and oxidative damage and affect our health – both physically and mentally! What sunscreen do you use?

My favorite protein powder

I love this one because _______. I use it in these ways ______, _______, ________.

Right now my favorite protein powder is a pea protein (made by Nuzest). I love this one because it’s gluten-free, dairy and soy free, GMO-free and is pea only (no other ingredients!). I just found out it’s also available in USA and other countries.

My favorite healthy protein bar

I love it because _______ AND/OR I tried ______ and don’t like it because ________. My clients are always looking for protein bars for a quick healthy snack but so many are loaded with sugar OR don’t have enough protein and fat OR are full of processed soy OR contain a ton of nuts OR aren’t gluten-free.

Thank you for being such a huge part of this community, for sharing your stories and successes and for offering words of encouragement to others in the community. Thank you too, for asking your questions. Keep the questions coming – they keep me on my toes and help me to learn too!

I’d love to hear how the above topics have helped you and what topics you’d like me to cover in 2018, plus which areas you’d like me to take an even deeper dive into.

Healthy travel food, first aid and avoiding anxiety and motion sickness when flying

November 3, 2017 By Trudy Scott 15 Comments

Updated: June 28, 2024

In today’s blog I share what I eat on a long international flight, plus what “first-aid” goodies I take in my carry-on luggage, how to stay cool, calm and collected when flying and demonstrate my favorite wrist bands for preventing motion sickness.

Even though I order gluten-free meals, I’m sure you’ll agree that the food on planes is pretty horrible and sometimes you can’t even be sure you’ll get your special meal. One flight we ordered gluten-free only to be told on the plane that they don’t serve gluten-free meals! Fortunately we did a layover in Hawaii and were able to buy a salad and some fruit after a lot of searching but it was not what you’d expect. It was a good thing we did take some snacks with us too but I am now way more prepared when I travel.

As you can see from the above image, this is the typical travel food (or “padkos” as we call it in South Africa) for a 13-hour flight:

2 organic apples
2 organic boiled eggs and some sea salt
Homemade biltong from grass fed beef (a South African version of jerky) made with sea salt, coriander and pepper
Coconut flakes and organic raisins
Sprouted pumpkin seeds (many nuts and seeds are medium and high oxalate but a few tablespoons of pumpkin seeds are low oxalate – more on oxalates here)
A selection of herbal tea bags: ginger (which is great for motion sickness), Nighty night which contains chamomile and is relaxing), Breathe Easy (in case of congestion) and rooibos (great for stress and an excellent source of polyphenols)
A can of wild salmon
Pea protein powder or whey or beef protein powder (as tolerated)

I also packed a meal of roast lamb with a veggie selection of carrots, zucchini and asparagus, plus some cauliflower sauerkraut. This was really delicious!

Also, to be safe, I take a selection of “first-aid” products in my carry-on luggage.

Here is some of what I typically pack for “first-aid”:

Arnicare which is an arnica gel * (for muscle pain)
Xlear nasal spray * and Biocidin throat spray * – I find that using these two products before boarding the plane and half way into the flight prevents me from picking up any bugs and getting sick
Tree tree oil *
Essential oils of lavender * (for relaxation and sleep) and peppermint * (for energy and a headache). Both are antibacterial too.
Melatonin spray * to help reset my circadian rhythm and help with jetlag
Designs for Health Oil of Oregano * and garlic supplements (not shown) for bug protection
Source Naturals GABA Calm for tension and anxiety. I didn’t use it/need it this trip but after my scary plane ride last year leading to vagus nerve issues, I’ve decided to always have some on hand when flying
Boiron Cold Calm, one of my favorite homeopathic cold remedies

I also take a few of each of the following in a supplement box: Designs for Health Inflammatone * (a natural anti-inflammatory), DPP-IV enzymes * (for accidental gluten exposure), activated charcoal * (also for accidental gluten exposure) and my daily supplements.

Note: the products marked with a * above can all be found on my Fullscript supplement store. And tryptophan, mentioned below, is also available on Fullscript.

Here is a video I did for the Healthy Travelers Global summit, an online event that was hosted by my good friend Robyn Benson in 2015 (just ignore the summit promo and enjoy the tips and demonstrations).

I share the following:

A quick demonstration using Xlear (notice that I actually miss my nose by mistake!) and Biocidin Throat Spray for avoiding bugs
The pressure-point wrist-bands I use for motion sickness (find them on Amazon here). Many people with pyroluria are more prone to morning nausea and may be very prone to motion sickness (and it’s commonly a sign of low vitamin B6). In order to be effective they do need to be put on BEFORE you start to travel and the position is key).
I don’t mention it in the video but motion sickness can be a sign of low bile production or poor quality bile. I share more about how I’ve been using ox bile to improve fat digestion and help with oxalate issues here. Hopefully this will help even more with my motion sickness.
Amino acids for travel anxiety (GABA for the physical anxiety and tryptophan for the fearful, worrying-about-flying anxiety)
Healthy travel snacks

Enjoy the beautiful Rocky Mountains! When I filmed this I was on a trip to St Paul, MN for the National Association of Nutrition Professionals conference and wanted to share just how I travel.

Additional resources when you are new to using amino acids such as GABA or tryptophan as supplements

As always, I use the symptoms questionnaire to figure out if low GABA or low serotonin may be an issue.

When considering them for flying I have clients do a trial before they leave and figure out optimal doses for their unique needs. And then use GABA and/or tryptophan as needed on the flight.

If you suspect low levels of any of the neurotransmitters and do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the practitioner/health team you or your loved one is working with.

There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, gluten, blood sugar control (this is covered in an entire chapter too), sugar cravings, anxiety and mood issues.

The book doesn’t include product names (per the publisher’s request) so this blog, The Antianxiety Food Solution Amino Acid and Pyroluria Supplements, lists the amino acids that I use with my individual clients and those in my group programs.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA QuickStart Program (if you have low GABA symptoms too). This is a paid online/virtual group program where you get my guidance and community support.

If you are a practitioner, join us in The Balancing Neurotransmitters: the Fundamentals program. This is also a paid online/virtual program with an opportunity to interact with me and other practitioners who are also using the amino acids.

Wrapping up and your feedback

I hope this is all helpful for your next long flight or even a road-trip you have coming up. Do keep in mind that some of this can be adapted for a day out shopping or a day at the beach too.

I’d love to hear about your favorite travel foods and first-aid goodies that you take on a trip.

Feel free to share and ask your questions below.

Teen Depression and Anxiety: Why the Kids Are Not Alright – my response

October 27, 2017 By Trudy Scott 10 Comments

Teens suffer from so much anxiety and their anxiety symptoms are now more of an issue than depression; they are cutting and self-harming as a way to feel normal; they are super-stressed; social media and iPhone use is taking over their lives, and in general, they seem to have poor coping skills.

This article in TIME magazine is a sad and concerning read: Teen Depression and Anxiety: Why the Kids Are Not Alright. It was written last year but is still very relevant. The author writes:

“Adolescents today have a reputation for being more fragile, less resilient and more overwhelmed than their parents were when they were growing up”

It’s an excellent article for creating awareness and to get an understanding of the extent of the issues and does highlight the crazy online world of teens:

It’s hard for many adults to understand how much of teenagers’ emotional life is lived within the small screens on their phones, but a CNN special report in 2015 conducted with researchers at the University of California, Davis, and the University of Texas at Dallas examined the social-media use of more than 200 13-year-olds. Their analysis found that ‘there is no firm line between their real and online worlds.’

Here is my response to the article and how I feel we can do better.

No solutions other than coping mechanisms

These teens are hopeless and resigned to the fact that this is how they are going to have to live i.e. simply managing their symptoms. It breaks my heart and it’s not alright!

Unfortunately (like the recent Xanax anxiety article in the New York Times) it offers no solutions other than coping mechanisms.

No mention of the importance of diet or nature

I agree that these kids are under a lot of stress (certainly more than when I was a teen) BUT there is ZERO mention of a real foods diet (that includes quality animal protein), a nourishing breakfast with protein (balancing blood sugar makes such a difference for reducing anxiety levels), the removal of caffeine, gluten and sugar, the importance of addressing nutritional deficiencies and poor gut health.

I love the movie project but there is no encouragement to get these teens out into nature (and maybe take up bouldering or gardening, both of which have been shown to reduce anxiety and depression).

No mention of DPA or GABA or tryptophan for self-harming, anxiety and addiction

The article makes the connections between the endorphin/opioid system and pain and the comfort these teens get from self-harming and cutting:

Scientists want to better understand how self-harm engages the endogenous opioid system–which is involved in the pain response in the brain–and what happens if and when it does

However, there is NO nutritional solution offered and NO mention of the amino acid DPA (d-phenylalanine), which can often be very effective for the cutting and self-harming, because it creates a similar endorphin boost that the cutting provides.

There is also NO mention of the calming amino acid GABA or the happy and worry-free amino acid tryptophan for the anxiety and worry.

All the above amino acid also address addictions and may well offer neurotransmitter support to help with the addictive nature of their “drug-of-choice” i.e. their iPhones, games and other devices.

We have a plethora of nutritional solutions

We have a plethora of nutritional solutions to consider. Here are some relevant blogs that need to be part of the conversation for these teens:

GABA for children: ADHD, focus issues, irritability, anxiety and tantrums
My interview with psychiatric nurse practitioner, Zendi Moldenhauer, on the Anxiety Summit – Anxiety in children, adolescents and young adults: an integrative psychiatric approach
My discussion with Dr. Nicole Beurkens at the end of one of Integrative Medicine for Mental Health conferences to talk about anxiety and the impact of both low zinc and low GABA. Nicole shares her perspectives on working with children and I share what I see with the adult women I work with.

Something as simple as a weighted blanket may help ease the anxiety some of these teens are experiencing.

We can do better than simply discussing the problem teens face. I’ve worked with both children and teens and we’ve shifted things in a matter of months. It really can be done but we need to share the powerful nutritional psychiatry solution, especially because research shows that most children with anxiety relapse, regardless of conventional treatment approaches.

Do you have a teenager who is experiencing anxiety and what has helped her/him?

Do you work with teens and do you incorporate some of these approaches?

How do we get this information into the hands of parents, schools, organizations, doctors, mental health practitioners and others those who can help make this happen?

Midday bright light therapy for bipolar depression

October 20, 2017 By Trudy Scott 6 Comments

A recent study from Northwestern University and published in The American Journal of Psychiatry: Adjunctive Bright Light Therapy for Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Trial has found that midday daily exposure to 7,000 lux bright white light for 6 weeks, significantly decreased symptoms of depression and increased functioning in people with bipolar disorder.

The press release issued by Northwestern University reports as follows

Previous studies found morning bright light therapy reduced symptoms of depression in patients with Seasonal Affective Disorder (SAD.). But patients with bipolar disorder can experience side effects such as mania or mixed symptoms from this type of depression treatment. This study implemented a novel midday light therapy intervention in an effort to provide relief for bipolar depression and avoid those side effects.

Compared to dim placebo light, study participants assigned to bright white light between noon and 2:30 p.m. for six weeks experienced a significantly higher remission rate (minimal depression and return to normal functioning). More than 68 percent of patients who received midday bright light achieved a normal level of mood, compared to 22.2 percent of patients who received the placebo light.

Images used with permission from Northwestern University

How the 7,000 lux bright light therapy was used

Here are the details of how the 7,000 lux bright light therapy was used in the study:

The light therapy patients were instructed to place the light box about one foot from their face for 15-minute sessions to start.

Every week, they increased their exposure to the light therapy by 15-minute increments until they reached a dose of 60 minutes per day or experienced a significant change in their mood.

Study lead author Dr. Dorothy Sit shares that starting low and slowly increasing the treatment made it more tolerable. None of the study participants experienced side effects, likely because the treatment was customized for each patient:

No one experienced mania or hypomania, a condition that includes a period of elation, euphoria, irritability, agitation, rapid speech, racing thoughts, a lack of focus and risk-taking behaviors.

A noticeable mood improvement with bright light therapy was also noticed as quickly as four weeks, which is similar to other light therapy research for non-seasonal depression and depression during pregnancy.

How do you do this in the middle of a work day?

You may have concerns about doing this at midday as this facebook follower voiced:

I guess if your bipolar depression is so debilitating that you cannot hold a job, then this is worth trying.

But 60 minutes!! What working person has 60 minutes in the middle of their workday?

It’s very doable because there are very nice desk versions that could easily be used at work (without anyone knowing – if privacy is a concern) or at a home-office desk for your convenience. I share some examples in this blog – Winter blues or SAD: light therapy.

I have tried lights in the morning but found that it caused agitation

I also received this feedback about increased agitation:

I have tried lights in the morning but found that it caused agitation. Over time my tolerance went down so that I could only use for less than 5 minutes. I haven’t ever tried midday light though. I’m not bipolar but I have depression which is generally worse in the winter. Exercise helps.

It may be worth trying midday light therapy if morning light therapy causes agitation or other adverse effects.

The press release mentions that light therapy is typically used in the morning to help reset circadian rhythms and the authors are unclear why midday light therapy worked for these patients with bipolar disorder. They plan to investigate further. If it is working via the same mechanism i.e. by resetting circadian rhythms, then it may well work at this time for other individuals too.

It may also be that your depression (and/or anxiety) is not caused by low serotonin but by something else instead – such as low catecholamines, poor thyroid health, gluten issues, poor diet and so on.

Using light therapy and tryptophan (or 5-HTP)

I have also found that some people do well on a combination of light therapy and tryptophan (or 5-HTP). One of my clients had many low serotonin symptoms and did better mood-wise and with reduced anxiety, on a small amount of tryptophan but still needed additional serotonin support. Additional tryptophan was too much for him and increased his day-time sleepiness, but using a small amount of tryptophan together with light therapy was the ideal balance for him.

Have you used light therapy with success – for the winter blues or depression or bipolar disorder? Or even for anxiety?

Have you ever used it at midday or at other times?

And have you used light therapy in conjunction with tryptophan or 5-HTP?

Collagen and gelatin lower serotonin: does this increase your anxiety and depression?

September 29, 2017 By Trudy Scott 471 Comments

I see everyone raving about gelatin and collagen – and rightly so – they have amazing health benefits. However, no-one is addressing the fact that gelatin is actually used in tryptophan-depletion studies to lower serotonin (gelatin is derived from collagen: when collagen breaks down, it becomes gelatin). When I first discovered this fact it really concerned me that this very important aspect is ignored so I added it to my long list of topics to investigate.

I posted the above on Facebook last month as part of a fact-finding exercise and appreciate all the feedback and questions. Today I share some of the feedback and research and I’d love to hear from you what your experiences have been.

I share how my experience with collagen left me flat and worried until I added tryptophan; feedback from individuals who wondered if collagen was affecting their sleep, making them moody, on edge or feeling night-time anxiety; some reported no mood issues when using collagen with tryptophan; feedback from many who didn’t notice any obvious mood issues at all ;and one woman who uses collagen ‘therapeutically’ to lower her serotonin levels.

I also share some very interesting research on why some people seem to be adversely impacted by acute tryptophan depletion/ATD (caused by collagen or gelatin consumption) while others are not. There are definitely some folks who are more susceptible.

The health benefits of collagen

In case you’re new to collagen, Dr. Josh Axe provides an excellent overview of the health benefits of collagen

Improves Health of Skin and Hair
Reduces Joint Pains and Degeneration
Helps Heal Leaky Gut
Boosts Metabolism, Muscle Mass and Energy Output
Strengthens Nails, Hair and Teeth
Improves Liver Health
Protects Cardiovascular Health

Gelatin is used in tryptophan depletion studies

Tryptophan-depletion studies have been done for years, as a way to study the relationship between low serotonin and depression. Often a tryptophan-deficient amino acid mixture is used for this purpose. More recently, collagen and gelatin are being used.

Collagen and gelatin are an excellent source of these amino acids: proline, glycine, glutamine and arginine, but they do not contain the amino acid tryptophan.

This paper, Pharmacokinetics of acute tryptophan depletion using a gelatin-based protein in male and female Wistar rats summarizes what we find in a number of studies that use gelatin for the purpose of lowering serotonin levels, in order to study the relationship between serotonin and behavior:

The essential amino acid tryptophan is the precursor of the neurotransmitter serotonin. By depleting the body of tryptophan, brain tryptophan and serotonin levels are temporarily reduced. In this paper, several experiments are described in which dose and treatment effects of acute tryptophan depletion (ATD) using a gelatin-based protein-carbohydrate mixture were studied in male and female Wistar rats.

My experience with collagen – flat and worried until I added tryptophan

When I recently injured my back and sprained my ankle, I decided to add collagen to speed up the healing and very quickly had to take a deeper dive into the topic because I noticed it affected my mood right away! I was using just one big scoop of collagen in a protein shake (pea protein) and yet I felt flat and slightly anxious within a day. It was the worried low-serotonin kind of anxiety in the early hours – something I haven’t felt in quite some time.

I wondered if it was due to the injury and inflammation my body was dealing with or if it was related to the effects of tryptophan depletion. I stopped the collagen and then added it back and had the same experience. I did this a few times and experienced similar feelings each time.

When I used tryptophan mid-afternoon and at bedtime I felt fine and was able to continue taking the collagen with no problems. I am prone to low serotonin – it was one of the root causes of my big anxiety issues in my late 30s – so I may be more affected than the average person.

Wondering if collagen causing mood issues and an increase in anxiety?

Here is feedback from someone who is wondering if collagen is causing her mood to dive:

I have wondered if it affects my mood so I haven’t been using it lately. Interested to see what other people say. I was using about a table spoon in a drink that I would sip on throughout the morning. My moods just take dives now and then. I have isolated gluten as a HUGE factor. I am forever wondering what else causes the dives and I began to wonder if collagen was causing problems so I haven’t used it in several months.

Stephanie feels moody when using collagen:

I have found that the days I take collagen that I’m moody. I’ve kept trying, but am always surprised by the reaction. I even mentioned it to my naturopath recently. Curious to see if there’s a connection.

Here is feedback from someone also reporting mood dives and feeling on edge (although as I pointed out to her the feeling on edge is very likely due to or partly due to the coffee):

I take collagen (grass-fed and grass-finished) in my coffee every morning. I’ve also had some mood dives consistently the last few months and feel more on edge. I’ve honestly never made the connection and actually thought it was hormones. Something to think about!

Melissa shared it affected her sleep:

As soon as I started taking gelatin daily I have had difficult falling asleep.

Katinka began having strange night time anxiety:

I did [Vital Proteins grass fed beef gelatin] for 2 weeks in bone broth. My nails grew like crazy, but at the same time I begun having strange night time anxiety: worry, obsessive, but not any of the other symptoms like depression and cravings. It is interesting to me because this was the only time I had anxiety at night since going gluten free.

Collagen caused a racing heart for Beverly:

Used to take Vital Proteins products. Was woken up several times in the night with racing heartbeat and out of breath. This went away when I stopped the collagen. I have symptoms of low serotonin but have not tried tryptophan

No noticeable problems

Many people shared that they didn’t notice any obvious mood issues so it’s clearly not a problem for everyone:

Jaime: Interesting, I use it almost daily for protein at breakfast. I will pay attention better. No obvious problems now (used for 9 months).
Angela: …I don’t think I have any side effects and I do have serotonin issues. I think I will have to do more research
Courtney: I just started using collagen peptides but not every day. Maybe once or twice a week. I haven’t noticed any difference in mood but I also just started taking it a few weeks ago.
Debra: I take 1bsp of Great Lakes Collagen Hydrosylate every day and take it to help heal my leaky gut….haven’t noticed any particular side-effects. I alternate it with the normal gelatin. I suffer from complex PTSD, anxiety and depression…I haven’t noticed any difference in that either

Jessica Drummond, nutritionist and physical therapist, and an expert on female pelvic pain and women’s health shared:

I use collagen regularly and I also eat quite a lot of meat and fish. For me both help me to feel very grounded and less anxious. I think of collagen as balancing for all of the muscle meat that we eat. I eat anywhere from 10-20 grams 4-5 days per week.

Feels anxious using gelatin, stop using it and anxiety is gone/less

Laura’s anxiety got worse within a few months of adding daily gelatin:

Wow, I never heard that gelatin can lower serotonin. I started using [Puritan’s Pride brand], 650mg, daily about 6 months ago to strengthen my nails. It’s worked very well for that. About a couple months ago my anxiety started to get worse again. My anxiety shows up as fear and worry mostly and not being able to quiet my mind. I had gotten it under control for almost 2 years now. I wonder if there is a connection. I’m going to stop taking the gelatin and see if my anxiety improves. I have not tried tryptophan, but I have found GABA helped quiet my mind and let me sleep better.

She decided to stop taking it to see if her anxiety symptoms would reduce and when I checked back with her she shared this:

I was surprised to find after about 2 weeks of stopping the gelatin, I began to feel more calm again and it’s been a lasting change. I still take zinc, vitamin b6 and lysine in the morning and GABA in the evening. This combination works well for me. I’m so grateful for all the information you share! Thank you!

Toni experienced something similar:

I’ve been using Organic collagen for about 8 months now… love the hair and skin results. My tummy felt better at first but not currently. My anxiety and panic attacks are off the charts: panic attacks, heart racing, sweating, brain fog. I want to escape -like fight or flight. Definately obsessing and fears. Memory difficulty. I have an upcoming GI appointment to check for Candida /SIBO… but I had no idea this could add to my anxiety. I’ll be looking forward to more information, Seriously.

And a few weeks after stopping the collagen she shared this:

I stopped using the collagen. Since then, my anxiety and panic are decreased by less than half. Mild in comparison. I’m definately taking a long break.

Keep in mind I’m not suggesting we should not be using collagen – just that if it seems to lower serotonin and increase anxiety/depression doing a trial with tryptophan may be the solution (more on that and some other possible causes of anxiety below).

When used with tryptophan – no mood issues

Karen uses collagen and tryptophan at night:

I use collagen every day. But hey, I also take L-tryptophan every night for anxiety. It runs in the family and a small amount of Tyrptophan at night helps resolve mine. No clue there was a connection

Maxine uses it every morning and takes 1 tryptophan before bed and reports no mood issues

I take it [Great Lakes gelatin and Vital Choice collagen] every morning in my tea and at night in my bone broth for my skin and joints and I take one tryptophan before bed. The tryptophan with GABA before bed is for better sleep. No mood issues.

Used ‘therapeutically’ to lower serotonin

Misty reports using it ‘therapeutically’ to lower her high serotonin levels. This application is new to me and I find it quite fascinating:

I use it to reduce tryptophan because I have a tendency toward high serotonin. I have suffered my entire life with ADD, tics as a child, grinding teeth, general anxiety, lack of motivation and later, IBS. In my quest to maximize my health, I finally came to these web pages for help. In my 53 years I’ve never been as calm as I am now. If I’m not careful, I can get a bout of IBS (not food related and trust me, from GAPS to AIP, nothing really affects me). I reduce tryptophan and I’m balanced. It seems contrary but it works for me and so many others

She links to these articles Tryptophan, Sleep, and Depression and The Sadder Side of Serotonin which both refer to the work of Ray Peat who I recently discovered is very much against the use of tryptophan.

I agree with the premise of too much serotonin causing issues (often the same symptoms we see with serotonin that is too low) but not the general message that tryptophan supplements and foods high in tryptophan are harmful and should be avoided by everyone. Based on the clinical results myself and other practitioners see boosting low serotonin with tryptophan and/or 5-HTP -and the wonderful results they experience – in my opinion, this is really all about biochemical individuality.

I decided to share this story here, even with the controversial tryptophan articles, because it illustrates that it is highly likely that the collagen is lowering her serotonin levels and making her feel better. I’ll tackle the above negative articles about serotonin and tryptophan in a separate blog post.

Why are some people adversely impacted by acute tryptophan depletion/ATD while others are not?

UPDATE: Dec 22, 2017. This section adds additional evidence or possibly some theories for why some people are adversely impacted when consuming collagen, while others are not impacted mood-wise – all related to the lowering of serotonin levels. These are called ATD or acute tryptophan depletion studies.

This paper: The effect of raising and lowering tryptophan levels on human mood and social behavior explains that effects of ATD can vary based on susceptibility of the study participants to clinical depression:

Acute tryptophan depletion (ATD) studies indicate that low serotonin can lower mood and also increase aggression, although results vary somewhat between studies with similar participants. Lowering of mood after ATD is related to the susceptibility of the study participants to clinical depression, and some participants show no effect on mood.

In healthy individuals, there is little or no lowering of mood, although results can be quite variable between studies, with some lowering of mood seen more often in women than in men.

The author reports the following variable responses:

In healthy participants with a family history of depression, there is a lowering of mood although mood remains within the normal range of mood.

In newly recovered depressed patients on antidepressants that act on the serotonergic system, 50 per cent or more of the patients show a temporary reappearance of the depressed mood they experienced before recovery.

In recovered depressed patients off antidepressants, only a small percentage of the patients show a marked lowering of mood.

In recovered depressed on noradrenergic antidepressants, there is no lowering of mood.

The results of the ATD studies suggest that lowering serotonin synthesis can lower mood in some circumstances, and that the magnitude of the effect tends to be greater in people with a greater susceptibility for depression.

Other studies report on these groups of people that were adversely affected with a lowered mood after ATD:

OCD / obsessive compulsive disorder: Patients with OCD experienced a decrease in control and an increase in interfering thoughts after acute tryptophan depletion. There was no effect on anxiety in this group.

Genetic polymorphisms: A number of papers show some genetic polymorphisms make some individuals vulnerable to increased depression after acute tryptophan depletion, such as MAOA and 5-HTTLPR (the serotonin transporter gene). In one 5-HTTLPR polymorphism study differences were seen between men and women: healthy men became more impulsive, whereas healthy women showed a mood reduction after ATD. Keep in mind that having a polymorphism doesn’t mean there will always be an issue, instead, it means there may be a predisposition.

Smokers: The moderating influence of nicotine and smoking on resting-state mood and EEG changes in remitted depressed patients during tryptophan depletion.

Comorbidity between depression and tobacco use may reflect self-medication of serotonergically mediated mood dysregulation [and acute tryptophan depletion or ATD] increased self-ratings of depressed mood [in certain smokers].

Although this study was looking at the role of nicotinic receptors in disordered mood and the self-medication of mood by smoking, we may be able to extrapolate this for our purposes because it was this one subset of smokers who were more depressed after tryptophan depletion. Could it be that smokers or even former smokers are more likely see increased depression after consuming collagen because it contains no tryptophan? Or is it that smokers tend to be drawn to smoking because they are prone to low serotonin?

Women ecstasy users: The effect of acute tryptophan depletion on mood and impulsivity in polydrug ecstasy users.

Women polydrug ecstasy users appear to be more susceptible than men to the effects of lowered serotonin levels [when they] received a tryptophan-deficient amino acid mixture and a control amino acid mixture containing tryptophan, at least 1 week apart.

The women who were impacted – with a lowering of their mood – used a tryptophan-deficient amino acid mixture and not collagen. The authors suggest this could be due to the drug-use causing progressive damage of serotonin neurons. Could this also happen with collagen consumption in current and possibly prior drug users? What about users of other street drugs or even medications that may also damage serotonin neurons?

Interestingly, in a study looking at five chronic fatigue/CFS patients, none of them showed any significant differences in fatigue, depression and concentration when subjected to acute tryptophan depletion /ATD. Was this group of patients too small or were none of them susceptible to low serotonin?

This is just a small selection of studies looking at the effects of acute tryptophan depletion or ATD but they give us much to think about when it comes to considering the varied effects we are seeing when individuals consume collagen.

If collagen affects you adversely and makes you feel more depressed, more anxious and experience worse sleep, can you relate to any of the above scenarios?

Resources if you are new to using the amino acids as supplements

If you are new to using any of the amino acids as supplements, here is the Amino Acids Mood Questionnaire from The Antianxiety Food Solution (you can see all the symptoms of neurotransmitter imbalances, including low endorphins).

There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, gluten, blood sugar control, sugar cravings, self-medicating with alcohol and more.

The book doesn’t include product names (per the publisher’s request) so as mentioned above, this blog, The Antianxiety Food Solution Amino Acid and Pyroluria Supplements, lists the amino acids that I use with my individual clients and those in my group programs.

As mentioned above, Lidtke Endorphigen is the DPA product I’ve had the most success with (and it can be found in my online store). Doctor’s Best D-phenylalanine is also a good product.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA Quickstart Program (if you have low GABA symptoms). This is a paid online/virtual group program where you get my guidance and community support. There are many moms in the program who are having much success with their kids.

You can then use this knowledge to then trial DPA and other amino acids or move on to the Amazing Aminos for Anxiety Program and get help there.

I would love your feedback. Do you use gelatin or collagen regularly i.e. daily or weekly? And why do you use it? How do you use it and what benefits do you notice?

Have you noticed any worsening of mood or an increase in anxiety or any of the other low serotonin symptoms? Do you take tryptophan to offset the fact that gelatin or collagen doesn’t contain any tryptophan?

Have you done the off/on test with collagen/gelatin and what was the outcome?

I’d love your feedback in the comments. Be sure to share what you’re using (collagen or gelatin and the brand), how much, how often you consume it, what you take it with, how much caffeine you consume, how much protein you consume on a daily basis and what kind of protein, and how you react to home made bone broth. If you’re comfortable with sharing how you score on the low serotonin questionnaire (now or in the past i.e. are you prone to low serotonin) and if you’re using a SSRI (or have in the recent past), this may help us piece the puzzle together.

Tyrosine for focus, motivation, energy, a good mood and possibly even anxiety

September 27, 2017 By Trudy Scott 42 Comments

Today I’m reviewing tyrosine, the amino acid that boosts catecholamines and helps with focus, motivation, energy (especially when you crave carbs for energy) and the blah kind of depression. It’s wonderful for helping you easily quit coffee/caffeine (when you are using it to “self-medicate” due to low catecholamines). It also provides support for the thyroid and surprising as it sounds, it may even ease some types of anxiety.

I’m also sharing some additional resources for you on tyrosine.

Tyrosine helps with energy, gives someone else migraines – look at precautions

Here is some feedback from my recent facebook post about tyrosine

Lorraine shared:

It really helped me have energy and endurance to be able to work out again! I went from not being able to even handle 20 minutes of weight lifting to doing regular 30 minute sessions and feeling energised and strong instead of depleted and exhausted.

Fay shared that it gives her a migraine. Migraines are one of contraindications with tyrosine if you are prone to them or have a history of migraines (and Fay does a history). This doesn’t mean you can’t ever benefit from tyrosine. With clients with migraine history we just start low, having them open a 500mg capsule and use just 50-100mg to start and then increase if they can.
Aaron Mello, Master Nutrition Therapist and founder of MoodFood Clinic, a practice that focuses on men’s mental health, loves using tyrosine with his clients and prefers it over phenylalanine because of the PKU contraindication. I agree and prefer tyrosine although I’ve only ever had one client with PKU. Aaron also mentioned that he also likes a combination product like Designs for Health DopaBoost: “I like that it has P5P and the mucuna is a natural source of L-dopa in addition to the tyrosine.” I do prefer standalone amino acids to start with (so just using tyrosine alone) but do also like the combinations in DopaBoost.

With all the amino acids, it’s important to be aware of the precautions. I mentioned PKU above. Here are other situations when tyrosine cannot be used: melanoma and Grave’s disease/overactive thyroid.

As with migraines, tyrosine does need to be watched with high blood pressure and bipolar disorder i.e. it may be tolerated and may not be tolerated. A trial will help you figure this out.

I personally can’t use either mucuna or tyrosine in large quantities but can tolerate the small amount in the Source Naturals GABA Calm product. The same tyrosine precautions do need to be considered when using GABA Calm for the low GABA type of anxiety.

Focus issues and ADHD – tyrosine or GABA?

Anxiety can often show up as focus issues or ADHD, especially in children who may not be able to articulate that they are anxious. Jenny is a mom in my facebook community and a friend of hers recommended GABA for her daughter after reading some of my posts. She shared this wonderful feedback:

My daughter hasn’t been diagnosed with ADHD but has a lot of ADHD qualities. We were having a huge amount of behavior problems as she is getting older (she’s 11). I did some research and went to the health food store and bought a bottle [of GABA Calm]. At this point I was mentally exhausted from all the fighting and drama at home and at school. I was desperate and didn’t want to put her on any hard medication.

She has had amazing behavior at school and at home since giving it to her. She’s almost like different child. GABA has truly changed our life. She’s been taking it for almost 2 months.

Anxiety and ADHD – where to start?

I recently received a great question from someone who heard my interview on the migraine summit:

I have a whole lot of overlap here. I’ve been diagnosed with ADHD with have anxiety issues. I also have a gluten sensitivity and migraines. Luckily, since I meditate daily, my migraines only occur every other month or so but usually involve weather changes.

It’s not uncommon to have overlaps and often addressing a few factors helps all issues. It sounds like she is gluten-free which is one common underlying factor in ADHD, migraines and anxiety. If someone is coming to see me for their anxiety we’ll work on that first – using GABA or tryptophan first – because tyrosine can help with ADHD but can make someone more anxious. We calm them first and then look at improving focus issues. With ADHD and anxiety, I also consider low blood sugar and making sure animal protein is being consumed at breakfast, and also check for low zinc and low iron (for starters).

GABA didn’t help her anxiety but tyrosine did

Everyone is different so using the trial method is the best way to figure out what you need. One of my past clients who had terrible anxiety, trialed both GABA and tryptophan and while she did get some benefits with both it just wasn’t enough.

She was sleeping better but still felt so stressed and anxious when preparing for an important meeting at work. The anxiety also seemed to get worse during the meeting which she was in charge of running. She did score high on the low catecholamines section on the amino acid questionnaire but were working on the anxiety before addressing poor focus and low motivation. It turned out that her anxiety escalated around her work meetings because of her lack of focus and low motivation – she was pushing herself to get through them. Once she added tyrosine her anxiety was under control. In this instance tyrosine actually helped ease the anxiety because he ADHD and motivation and drive improved!

Using tyrosine

Here is one tyrosine product I use (there are many others on the market)

Progressive Labs tyrosine 500mg: 500mg l-tyrosine. As I mentioned this is the last amino acid I trial with my anxious clients because it can make you more anxious (although as I mentioned above, with one client, it reduced her anxiety because she was able to focus better at work).

As with all the amino acids, when using tyrosine:

Start low (500mg is a typical starting dose) and increase as needed.
Do a trial to determine if the ADHD, fatigue, depression, low motivation is due to low catecholamines. I always do this with clients before starting any amino acid. Be sure to read how to do an amino acid trial. It has the amino acid questionnaire, the precautions and information on how to use targeted individual amino acids.
Take between meals and away from protein for the best effects

Tyrosine should never be used after 3pm as it’s too stimulating when used after this time. For my clients with sleep issues we go slow and stop after the mid-morning dose until we determine if sleep is being affected.

This blog post is part of the series of amino acid product reviews:

The resources in this blog and my other articles are intended to be used in conjunction with my book: The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings. If you do not have my book I highly recommend getting it and reading it before jumping in and taking the amino acid supplements.

There is a complete chapter on the amino acids and one for pyroluria, plus information on real whole food, sugar and blood sugar, gluten, digestion and much more.

You can find the tyrosine product I recommend on this blog: The Antianxiety Food Solution Amino Acid and Pyroluria Supplements

For today’s tyrosine review:

What about your success stories with tyrosine? how has it helped you?
Or has it been an issue for you?
As I mentioned above it’s the last amino acid I used with my anxious clients because it can make you more anxious but it may just help your anxiety

If you have questions or feedback please post them below or on the supplements blog