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KetoNutrition: From Science to Emerging Applications and Practical Implementation

May 4, 2018 By Trudy Scott Leave a Comment

I had the pleasure of hearing Dominic D’Agostino, NASA crew member, researcher and Associate Professor at the University of South Florida present on “KetoNutrition: From Science to Emerging Applications and Practical Implementation” at the 6th BioCeuticals Research Symposium in Melbourne last weekend. His presentation was based on decades of evidence that supports the anticonvulsant and neuroprotective properties of nutritional ketosis. It was one of my favorite presentations and I’m thrilled to share some of the highlights with you here.

Ketones are alternative fuels and neuroprotective signaling metabolites – increasing longevity, lowering inflammation, dampening oxidative stress, lowering glutamate and raising GABA.

In this slide he shared how the proven applications of nutritional ketosis are extensive – including epilepsy, type 2 diabetes, weight loss, NAFLD, mitochondrial disease and inflammation, GLUTID Syndrome, PDH Deficiency, Lennox-Gastaut Syndrome, Dravet Syndrome and Rett Syndrome.

There is emerging evidence for acne, PCOS, exercise performance, wound healing, longevity, cancer, CNS Oxygen Toxicity, autism, Angelman’s Syndrome, ALS, MS, Neuropathies, Alzheimer’s disease, brain injury, neurodegeneration, anxiety, depression, bipolar and schizoaffective disorder.

Seizures, cancer and the ketogenic diet

 

In his TEDx talk from 2013 Dr. D’Agostino shares the benefits of a ketogenic diet for seizures and how while studying the effects of gasses on the brains of Navy Seal divers, he developed an approach for metabolically starving cancer cells through diet and compressed oxygen, replacing chemotherapy, surgery, or radiation.

He ends by saying this:

Future treatments and prevention of many diseases may fall back on the ancient wisdom of Hippocrates when he said “let food be thy medicine”

As you can see from the applications slide above, much more research has been done on the therapeutic benefits of a ketogenic diet since this 2013 TEDx talk.  And food truly is medicine!

In one of his studies, the first paper above, ketone supplementation was found to have an anti-anxiety effect – Exogenous Ketone Supplements Reduce Anxiety-Related Behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk Rats:

We conclude that ketone supplementation may represent a promising anxiolytic strategy through a novel means of inducing nutritional ketosis.

Adenosine and the adenosinergic mechanism

He shared a number of studies that describe how the anti-anxiety and anti-convulsant effects of ketone supplementation are mediated, in part, through the adenosinergic mechanism. This was one of his papers – Anxiolytic Effect of Exogenous Ketone Supplementation Is Abolished by Adenosine A1 Receptor Inhibition in Wistar Albino Glaxo/Rijswijk Rats.

Adenosine is a neurochemical which many coffee-drinkers may be familiar with since: “Caffeine increases wakefulness [and often anxiety] by antagonizing adenosine receptors, and adenosine itself promotes sleepiness” and a feeling of calm.

Older research finds that there is the “involvement of adenosinergic receptor system in anxiety related behaviours.” More recent research describes adenosine as “a mediator with multisystemic effects”, and it is produced by almost all cells, playing a role in heart function, sleep, bone health, activation of the immune system and mediating the effect of various hormones. I expect we’ll be hearing a great deal more about adenosine in relation to ketogenic diets in the near future.

The microbiomes of astronauts sync up and so do their serotonin levels

This was one of my favorite presentations at the BioCeuticals Symposium and it was really great to meet Dominic afterwards and learn more about future anxiety research. He shared that his lab has planned research on the benefits of ketosis for both anxiety and improved cognitive function.

It was also fascinating learning from someone who has been in space and hearing how the microbiomes of the astronauts sync up when they are all in space together. And so do their serotonin levels.

If the ketogenic diet is new for you or you want to see the latest research, check out Dominic’s work at Keto Nutrition. And if you want to learn more from Dominic and other keto experts, the Keto Edge Summit runs all of next week.

I also write about two schizoaffective case studies here and share questions and concerns I have about the ketogenic diet. It’s not a panacea for everyone in all instances. But the therapeutic benefits are profound when someone needs to adopt this dietary approach.

Feel free to ask questions and share you experiences with a ketogenic diet – in the comments below.

Filed Under: Anxiety, Bipolar disorder, Ketogenic diet Tagged With: adenosine, adenosinergic, anxiety, autism, cancer, depression, Dominic D'Agostino, keto, Ketogenic diet, ketosis, schizoaffective disorder, seizures, weight-loss

Could yeast infections impair recovery from mental illness?

April 13, 2018 By Trudy Scott 3 Comments

Julia Rucklidge, PhD, is an associate professor in the Department of Psychology, University of Canterbury, Christchurch, New Zealand and has published a number of studies looking at “micronutrients to treat psychiatric disorders including attention-deficit/hyperactivity disorder (ADHD), mood disorders, stress, and anxiety,” where benefits were reported. “Despite the positive benefits associated with micronutrients, some factors may limit a positive response, one of which may be the overgrowth of intestinal Candida.”

In this 2013 paper, Could yeast infections impair recovery from mental illness? A case study using micronutrients and olive leaf extract for the treatment of ADHD and depression the authors discuss the impact of candida on gut health and response to supplementation:

a number of factors influence optimal response and absorption of nutrients, including the health of the gut, particularly the presence of yeast infections, such as Candida.

As part of a wider investigation into the impact of micronutrients on psychiatric symptoms, many participants who experienced a yeast infection during their treatment showed a diminished response to the micronutrients.

One particular female client was followed for a 3-year period:

Kate (an alias) is a 24-year-old female of European descent who had participated in the 2010 trial by Rucklidge et al using micronutrients for the treatment of ADHD. In the past, she had been prescribed methylphenidate [Ritalin] by a psychiatrist but could not tolerate the side effects.

For just over 2 years, while using the micronutrient, she had no ADHD or mood symptoms, other than a mild increase around her period.

About 2.5 years participating in the trial, Kate started to feel increasingly unwell and reported the following:

(1) a chronic sore throat; (2) a constant runny nose; (3) cramps; (4) itchy toes, anus, and vagina; (5) rashes on her legs and groin area; and (6) an overall flu-like feeling. Concomitantly, all her psychiatric symptoms had returned… She was moody, anhedonic (unable to experience pleasure), and chronically irritable and was having cravings for sugary and starchy foods. Kate visited her family physician, who diagnosed Kate with a vaginal yeast infection

Over the next year, it was found that her psychiatric symptoms (ADHD and mood) got worse when she was infected with Candida and then her ADHD and mood symptoms improved once she was successfully treated with olive leaf extract and probiotics.

The study makes this conclusion about the role of inflammation, gut health and nutrient absorption:

This case outlines that micronutrient treatment might be severely compromised by infections such as Candida and may highlight the importance of gut health when treating psychiatric disorders with nutrients.

Given the role that inflammation can play in absorption of nutrients, it was hypothesized that the infection was impairing absorption of the micronutrients.

The authors also mention the growing body of literature on the gut-brain connection and how

the gut microbiota can influence brain function and subsequent psychiatric functioning.

Candida is always considered as one of many possible root causes with my anxious clients – it can contribute to anxiety as well as ADHD and depression, and out-of-control-sugar and intense carb cravings.

Olive leaf extract is one of many approaches for eliminating candida is more commonly used in Australia and New Zealand.

Another approach is to use garlic and oregano to kill the candida. I have great success with these products from Designs for Health:

  • Allicillin – a garlic product that contains Garlicillin®, a blend of garlic oil and parsley oil with specified levels of garlic sulfides and ajoene, the most bioactive compound formed from garlic and
  • Oil of Oregano – which has powerful antioxidant and intestinal cleansing benefits. It also helps to maintain a healthy microbial balance. This product is standardized for carvacrol and thymol, the principal phenolic compounds in oregano

Probiotics are also part of the protocol, as are dietary changes. Fresh garlic, onion, daikon, olive oil, coconut oil, lemon, apple cider vinegar, fermented vegetables and coconut oil are all therapeutic foods on an anti-candida diet.

In addition to killing the candida and restoring the good bacteria with probiotics, I also use targeted individual amino acids to help reduce the sugar and carb cravings, making it easier to quit the bread, sugar, cookies, cakes and fruit. These amino acids can also help to alleviate some of the anxiety, mood and ADHD symptoms from day one, offering relief and hope right away since eliminating candida is not a quick process:

  • tryptophan for afternoon cravings and mental worry (tryptophan also has some direct anti-candida effects – more to come on this in the future blog)
  • GABA for stress-related cravings and physical anxiety
  • glutamine for intense sugar cravings and low blood sugar
  • DPA for reward eating and weepiness
  • tyrosine for cravings due to low energy and low motivation
[all of the above supplements, including Allicillin, Oil of Oregano, various probiotics and an olive leaf product, called Olivirex Combination, can be ordered via my online store – details for creating an account on my supplements page. The category once you login is candida/dysbiosis]

Have you experienced anxiety, depression, panic attacks, ADHD and cravings with candida?

Have supplements that worked in the past stop working while you’re dealing with the candida?

Have you found the amino acids to help with anxiety and cravings while you’re addressing your candida?

Filed Under: Candida Tagged With: ADHD, allicillin, anxiety, candida, depression, Julia Rucklidge, olive leaf, oregano, probiotics, sugar cravings, yeast infection

Ketogenic diet: reductions in auditory hallucinations and delusions, better mood and energy, and weight loss

April 6, 2018 By Trudy Scott 5 Comments

Two schizoaffective patients of Dr. Chris Palmer, a psychiatrist from Harvard’s McLean Hospital in Belmont, Massachusetts, tried a ketogenic diet for weight loss. As well as losing weight, they experienced reductions in auditory hallucinations and delusions, had a better mood and had more energy.

Here is additional information about these remarkable results, published late last year in this letter to the editor – Ketogenic diet in the treatment of schizoaffective disorder: Two case studies.

The male patient: lost weight, reductions in auditory hallucinations and delusions, better mood and energy

The male patient, diagnosed with schizoaffective disorder, with a prior psychiatric history of attention deficit hyperactivity disorder and major depression, experienced “dramatic” reductions in auditory hallucinations and delusions, as well as better mood and energy on the ketogenic diet. He also lost weight, losing 104 pounds over the course of a year.

He weighed 322 lb and wanted to lose weight by following a ketogenic diet, typically consisting of coffee with medium chain triglyceride (MCT) oil and butter (“bulletproof coffee”), eggs, meat, fish, poultry, spinach, kale, and olive oil. Within 3 weeks, he had lost 15 lb, but also noted a dramatic reduction in his auditory hallucinations and delusions, and improvement in his mood, energy, and ability to concentrate. For the past year, he has largely remained on this ketogenic diet and has lost 104 lb.

His functioning has improved and he has become more independent:

He completed a certification course, successfully participates in an online college program, has friends, began dating, and moved from his father’s home into an independent apartment.

The female patient: lost weight, resolution of her delusions

After four weeks on the ketogenic diet, the female patient, also diagnosed with schizoaffective disorder, and with a prior psychiatric history of major depression and anorexia nervosa, had resolution of her delusions and lost ten pounds:

she wanted to lose weight, and went on a ketogenic diet, consisting mostly of coffee, eggs, poultry, and lettuce. Within 4 weeks, she lost 10 lb and noted that her delusions were no longer present, and that her mood and energy were much better. After 4 months, she lost a total of 30 lb and her PANSS score decreased to 70 [down from 107]

In both instances their symptoms returned when they stopped the diet, but then improved again when back on the ketogenic diet.

In case you’re not familiar with the ketogenic diet here is a quick summary:

The ketogenic diet is a high-fat / low carbohydrate [and low protein] diet that has been used since the 1920’s to treat childhood epilepsy, with some studies suggesting that over 50% of patients experience significant reductions in seizure frequency. The ketogenic diet results in ketone bodies, instead of glucose, being used as the primary energy source in the brain.

There simply is no psychiatric medication available with the power to accomplish these results

I had the pleasure of meeting Dr. Georgia Ede, MD  last year at the ISNPR conference. She is a Harvard-trained psychiatrist and nutrition consultant practicing at Smith College, and writes about these two schizoaffective cases in her article – Low-Carbohydrate Diet Superior to Antipsychotic Medications:

These outcomes are truly remarkable: improvement by dozens of points on the PANSS, significant weight loss, and better quality of life. There simply is no psychiatric medication available with the power to accomplish these results.

I agree with Dr. Ede especially when we look at the medications these patients had trialed. These medication trials for the male patient: methylphenidate, amphetamine salts, dextroamphetamine, bupropion, sertraline, paroxetine, buspirone, lamotrigine, lorazepam, clonazepam, gabapentin, haloperidol, perphenazine, aripiprazole, olanzapine, quetiapine, and clozapine. The female patient had a similarly long list of medication trials and she also received 23 electroconvulsive therapy treatments. For both of them, positive and negative symptoms persisted.

I do still have questions about the ketogenic diet

The research in epilepsy is extensive and the research in mental health is growing. I am really impressed with the results, but I do still have questions about the ketogenic diet. Perhaps you have some similar questions and concerns. Here goes…

  1. If this particular nutritional psychiatry approach works so well for severe mental health disorders such as schizophrenia and psychosis, how will it work for less severe conditions like anxiety and panic attacks? Are these severe cases like the “canaries in the coal-mine” paving the way and teaching us about the benefits of this way of eating?
  2. Should you use a ketogenic dietary approach as the first approach or consider it as a last resort once the other dietary approaches have been implemented and you’re not seeing full symptom resolution? In other words, should you start with a real whole foods diet, then implement a gluten-free diet, then a grain-free diet, then remove dairy (if it’s an issue), then incorporate low FODMAPs if needed and only then implement a ketogenic diet? (low oxalate, low salicylate and low histamine would be incorporated as needed earlier in the process, based on each person’s unique needs).  If we look only at schizoaffective disorder,  there is growing evidence of the role of gluten  in some individuals with this paper “suggesting that an antigliadin IgG positive population of schizophrenia could be a distinct subgroup.” This 2 person pilot study reports the benefits of a gluten-free diet: “this potential mechanism is exciting and may provide improvement for up to one-fourth of patients (antibody-positive) who suffer from this devastating disorder.”
  3. How do we clearly define a ketogenic diet and communicate this definition to practitioners and to those who choose to implement this way of eating on their own? I’ve had feedback from many people who tell me they have been on a ketogenic diet (and it’s worked well for them or maybe it hasn’t worked so well for them), only to discover they are not really eating a true ketogenic diet. How do we simplify this way of eating and make it easy for individuals to understand and then stay in ketosis?
  4. How do we create a ketogenic diet that is nutrient dense and also offers the benefits seen in this research. I have major concerns about long-term nutritional deficiencies with a diet of coffee, eggs, poultry, and lettuce (as eaten by the female patient in this case study). It should ideally include plenty of leafy greens, non-starchy vegetables like broccoli, cauliflower, asparagus etc. and healthy fats like avocado, grass-fed butter and coconut oil, together with fermented vegetables and bone broths. I’m also not convinced that coffee should be part of the ketogenic diet, especially if coffee increases your anxiety and affects your sleep.

  1. How do we help individuals make the switch to this way of low carb eating and help them maintain so they don’t feel deprived and are not relying on willpower alone? As you can see from these 2 cases, the diet can be challenging to sustain and slip ups are common. If you are eating enough health fats (and it’s a lot more than you’re used to eating), this typically helps with cravings. If you still have cravings and feel you are deprived and missing out on treats, the targeted individual amino acids offer powerful results: tryptophan (for afternoon cravings), GABA (for stress eating), DPA (for comfort eating), tyrosine (when there is low motivation) and glutamine (for low blood sugar cravings).
  2. Is the ketogenic diet the next big fad or weight-loss trend as we’re hearing in the media? Based on the above research it truly does have impressive therapeutic benefits beyond only weight-loss. So can we see similar benefits with a modified ketogenic diet, using intermittent fasting and/or cycling in and out of ketosis, and even adding in a ‘feasting day’ of carbs?
  3. Who shouldn’t adopt a ketogenic diet? For example: those with the APOE4 gene, women with adrenal and hormone issues, and individuals with thyroid issues and no gallbladder? The question then becomes this: of those suffering with anxiety and depression or another mental health disorder, who doesn’t have one of these issues? And how do we address the keto rash, constipation, fat malabsorption, fatigue, mineral deficiencies and other issues some people experience on a ketogenic diet?

Right now, this is my thinking: as with any nutritional or functional medicine approach, I would say there is no one-size-fits all for who should implement a ketogenic diet (we need to consider the unique biochemistry of each person) and there is no one set ketogenic diet (it will need to be customized for each person).

Please do share if you’ve adopted a ketogenic diet and the benefits you have experienced, and if you experienced any issues. Be sure to share what a typical day’s diet looks like for you.

Filed Under: Anxiety, Diet, Sugar addiction Tagged With: anxiety, coffee, delusions, depression, diet, Dr. Chris Palmer, energy, hallucinations, Ketogenic, mood, schizoaffective, weight-loss

Wi-Fi is an important threat to human health and may contribute to unresolved anxiety, SIBO, oxalate issues and high cortisol

March 30, 2018 By Trudy Scott 32 Comments

A new paper by Martin Pall, Wi-Fi is an important threat to human health, states the following:

Repeated Wi-Fi studies show that Wi-Fi causes oxidative stress, sperm/testicular damage, neuropsychiatric effects including EEG changes, apoptosis, cellular DNA damage, endocrine changes, and calcium overload.

He states that EMF effects are often cumulative, EMFs may impact young people more than adults and that voltage-gated calcium channel (VGCC) activation plays a role in all seven effects:

Each of these seven is also produced by downstream effects of the main action of such EMFs, voltage-gated calcium channel (VGCC) activation.

Peroxynitrite is a very powerful oxidant leading to major oxidative stress in the body and his landmark VGCC paper covers how peroxynitrite is created:

EMF activation of VGCCs leads to rapid elevation of intracellular Ca2+ [calcium ions], nitric oxide and in some cases at least, peroxynitrite

I’m studying the human threats of Wi-Fi and EMFs in the practitioner ElectrosmogRx course being taught by Nick Pineault, so the timing of this new paper is excellent.  Nick’s course is highly recommended too.

I’ll have much more to share once the course is over but this is just some of what I’ve learned so far about the biological impacts of EMFs (other than what is mentioned in the above new paper by Martin Pall):

  • A contribution to mitochrondrial dysfunction
  • Increased inflammation
  • Glutathione depletion
  • Glutamate excitotoxicty
  • Break down of the blood brain barrier and other barriers like the gut
  • Melatonin depletion

And much more – all of which have major implications for mental health (and other health conditions too of course).

My speculations about chronic anxiety, insomnia, benzodiazepine issues, SIBO and oxalate issues

Based on the above and making some extrapolations from the research I am speculating that EMF overload may play a role in the following situations in some susceptible individuals:

  • Why some individuals have chronic high cortisol and yet nutritional support for the adrenals offers minimal help? And why some individuals continue to experience anxiety and insomnia (due in part to high cortisol and/or low melatonin) despite making all the root cause changes to diet, addressing gut health and addressing nutritional deficiencies? Or why ongoing nutrient support is needed despite following a healthy lifestyle?
  • Why some individuals on benzodiazepines have such a difficult time with tolerance, physical dependence and tapering, and even continue to experience adverse effects long after their last dose. This is based on extrapolations from research showing “Chronic benzodiazepine administration potentiates high voltage-activated calcium currents in hippocampal CA1 neurons”
  • Why so many have issues with dietary oxalates (found in nuts, wheat, leafy greens like spinach, strawberries, eggplant, kiwi fruit and other healthy vegetables and fruits) leading to increased anxiety and pain. I’m just starting to look at all the research – here is one paper that discusses the effects of electromagnetic radiation on the rat kidney: “kidney tissue is extremely sensitive to oxidative damage since it is one of the organs involving intense oxidation processes”
  • Why we are seeing such an increase in SIBO (small intestinal bacterial overgrowth) and why are there so many individuals who cannot resolve their chronic SIBO.  I’m still looking for some research linking EMFs and SIBO and/or IBS but Nick writes about this in his book. Is the high use of the cell phone for texting and communicating on social media playing a role since you hold your phone on your lap right by your belly? I did find this interesting research: could oxalate issues be contributing to chronic SIBO?

If you can relate to any of the above and you are now wondering if your Wi-Fi exposure could be playing a role, I’d love to hear from you in the comments. Please share your situation and symptoms and your current Wi-Fi and EMF exposure i.e. what are you being exposed to and for how long each day are you using various devices.

How to start mitigating your EMF exposure

I’ll be sharing more in the next few weeks, connecting some of the dots, digging into the research and sharing all the steps you can take to mitigate your EMF exposure. Here are some tips to get you started right now:

  • No electric blanket or clock radio next to your bed
  • Never have your cell phone on in a moving car (you can use Google maps with your cell phone on airplane mode – just do the search first and then put your phone on airplane mode)
  • Always have your cell phone on airplane mode at night (it’s even better to switch it off completely) and when carrying it in your bag or on your person
  • Never hold your cell phone to your ear – only ever speak on your cell phone using the speaker or use a hollow-tube headset
  • Stop texting/reading social media with your phone on your lap (it’s right by your belly and may be affecting your microbiome)
  • Do not allow children to use your cell phone or iPad or similar smart device unless they are on airplane mode.
  • Remove Wi-Fi from your home or at least (for starters) switch it off at night
  • Get rid of your wireless “toys” like wireless keyboard and mouse (I really didn’t want to get rid of mine)
  • Work on your laptop via an external wired keyboard and work on battery mode (charging it when you’re not working)
  • Get rid of cordless phones and get a corded phone

Nicolas Pineault is an investigative journalist and is the author of “The Non-Tinfoil Guide to EMFs” (my Amazon link). He is an expert on EMFs and his book is a wealth of knowledge.

I’d love to hear your level of awareness and concerns about the risks of EMFs? And what you currently do to reduce the risk for you and your family? And have you noticed any improvements in health or strange symptoms?

Or are you not concerned?

If you’re a practitioner is this something you discuss with your clients or patients? Have you observed they respond better to your recommendations and heal more quickly?

Filed Under: EMFs, Environment Tagged With: anxiety, depression, DNA damage, EMF, glutathione, health, Inflammation, melatonin, peroxynitrite, VGCC, Wi-Fi

An “omnivore” like diet or Paleo diet is associated with reduced anxiety and depression

March 23, 2018 By Trudy Scott 12 Comments

A new study published last month, Do patterns of nutrient intake predict self-reported anxiety, depression and psychological distress in adults? SEPAHAN study, reports that

An “omnivore” like diet high in amino acids, cobalamin, zinc, phosphorus, saturated fat, cholesterol and pantothenic acid is associated with reduced psychological disorders.

This was a cross-sectional study, meaning it was a type of observational study design where the outcome and the exposures in the study participants are measured at the same time. The aim was to find an association (rather than causal relationship) between patterns of nutrients intake and psychological disorders such as anxiety and depression.

The study authors had 3846 Iranian adults between 18 and 55 of age complete questionnaires in order to assess their diets and nutrient patterns, as well as psychological factors including anxiety, depression, and overall health in general. This group comprised 1712 males and 2134 females.

The study results

After calculating the daily intakes of 57 nutrients (including individual amino acids,

starch, dietary fiber, simple sugars, different fatty acids, vitamins, minerals, and bioactive substances), 3 nutrient patterns were identified:

1) the “omnivore” pattern

high in individual amino acids, cobalamin, zinc, phosphorus, saturated fatty acids, cholesterol and pantothenic acid

in both women and men, with pyridoxine (vitamin B6) high in men only

2) the “grains and dairy” pattern

high in thiamin, folate, selenium, iron, starch, maltose, betaine, calcium, riboflavin, and niacin

and low in the following

mono-unsaturated fats, vitamin E and polyunsaturated fats

3) “fruits and vegetables” pattern

high in copper, vitamin C, glucose, fructose, potassium, dietary fiber, sucrose, vitamin A, magnesium and vitamin K.

These are the associations that were observed after adjusting for confounding factors:

  • Men in the top tertile of the omnivore nutrient pattern had lower anxietyand depression scores than those in the bottom tertile
  • Women in the top tertile of the omnivore nutrient pattern had better overall poor health scores than those in the bottom tertile and had lower odds of psychological distress, such as anxiety and depression.

This type of diet is also referred to as a Paleo or cave-man type of diet. Even though this study was only showing associations and not a cause-and-effect, it’s still very encouraging to see new research in the field of nutritional psychiatry, further supporting the results we see in clinical practice.

What are the mechanisms?

The high amino acids provide the building blocks for the production of our feel-good neurotransmitters such as serotonin, GABA, dopamine and endorphins, with zinc being a key co-factor for making these brain chemicals. The authors share some of the mechanisms for the association in the discussion section of the paper:

Dietary protein intake and also individual amino acid status have been linked to psychological status in previously published studies. For instance, methionine in the form of S-adenosyl-L-methionine, tryptophan and serine were inversely associated to depression. Lysine, arginine, beta-alanine, tryptophan and tyrosine have been shown to have anxiolytic effects. As amino acids are important precursors for neurotransmitters; they might affect psychological condition. Important neurotransmitters like dopamine and serotonin are made from amino acids tyrosine and tryptophan, respectively.

Pantothenic acid is a B vitamin that is key for stress and adrenal health. Low levels of B12 or cobalamin can be associated with both anxiety and depression, as well as fatigue. Both zinc and B12 are common deficiencies, and more so in vegetarian and vegan diets. The authors discuss some possible zinc mechanisms:

  • zinc has antidepressant-like activities such as up-regulation of the expression of brain derived neurotrophic factor (BDNF) gene
  • zinc is an antagonist of the glutamate/N-methyl-D-aspartate (NMDA) receptor

Seeing saturated fat and high cholesterol mentioned in favorable terms in a study – both of which are needed for a healthy brain and for good blood sugar control – is always exciting. The authors discuss these possible mechanisms:

low serum total cholesterol may increase the risk of depression and suicide attempts. It is hypothesized that low cholesterol intake might cause a depressed central serotonergic activity which in turn leads to depression.

Here is my addition to the discussion: in our interview on a prior Anxiety Summit, Dr. Kurt Woeller and I discuss the link between low cholesterol and low oxytocin and the role this plays in anxiety, social bonding and depression.

One area I’m a little confused about is the findings on pyridoxine (vitamin B6). They report it was high only in men in the omnivore group, and not in women. As they report, vitamin B6 is also a key co-factor in the serotonin-tryptophan pathway and we know it’s important for alleviating anxiety- related PMS symptoms in women. It’s mentioned in the concluding paragraph for playing a role in the association for both men and women and yet it is not mentioned in the abstract. I’ll report back as I find out more.

Here are some actual real-life results from someone eating this way

I blogged about anxiety and depression success stories on Paleo and grain free diets around this time last year. I shared Andrea’s feedback about her diet-mood results with a grain-free and high fat diet:

I happened upon a fat loss diet that had me cut out grains, most dairy, and sugar while focusing on mostly meat, fish, fats from nature such as butter, olive, and coconut oils. Nuts, seeds, and legumes were allowed too. These rules made it so I had to avoid processed foods. There was one day a week of eating anything.

Within 6 weeks I was shocked that I got much much more than fat loss. My depression, anxiety, mood swings, sleep issues and all but one pesky health symptom disappeared. I was stronger, faster, and felt energy I never remember having.

Have you found benefits with an omnivore or Paleo diet? Less anxiety and depression? Better overall health? More energy? Better sleep?

If you’re a practitioner have you found this approach works with your clients/patients?

Filed Under: Diet Tagged With: amino acids, anxiety, cave-man diet, depression, health, omnivore, paleo, psychological distress, saturated fats, zinc

New book: The Healing Power of Essential Oils

March 19, 2018 By Trudy Scott Leave a Comment

The Healing Power of Essential Oils: Soothe Inflammation, Boost Mood, Prevent Autoimmunity, and Feel Great in Every Way by Eric Zielinski, launched last week and I promised you a book review so here goes. I have always loved Dr. Z’s research-based approach and practical how-tos when it comes to essential oils and was so excited for this book. Well, all I can say is that this is one of the best books I’ve read this year! I read it cover-to-cover in one sitting and I have lists of things I want to try!

It’s perfect for you if you’re:

  • a total newbie to essential oils and have been hearing how great they are and want to learn the basics (and the science)
  • someone like me who does has been using essential oils for a few years but could really take things up notch in terms of therapeutic use and how to use blends
  • someone who is well versed in using essential oils therapeutically, making your own cleaning products and self-care products and wants the science behind each essential oil
  • looking for a great resource to give a loved one like your sister or mom, or to a friend, and if you’re a practitioner, as a resource for your clients and patients, so they too can benefit by what you already know
  • looking for a non-branded resource (Dr. Z has no brand loyalty but does teach you how to find quality brands of essential oils)

Here are some of the many reasons I love this book:

  • Dr. Z emphasizes biochemical individuality – just like with food and nutrients there is no one size fits all with essential oils and you have to find what works for you. He teaches you how to figure that out in the recipes sections
  • He addresses the ‘overwhelmed and where do I start’ aspect – he calls it “paralysis by analysis”. One way he does this in a few ways: 7 steps to start using them, a daily morning and/or evening practice and the tops oils everyone should start with. Here’s another idea (from me): start with a calming essential oil like lavender or neroli!
  • The background information is excellent: the source of the essential oil (for example cinnamon bark vs the leaf); why knowing the chemotype is important in terms of their different therapeutic effects; shelf life; how to find quality oils; why plants native to an area are better; dilution rules; inhalation, topical use and ingestion of oils
  • The research is comprehensive and best of all he refers to studies where the essential oil has been shown to provide therapeutic value, rather than referencing studies on various constituents
  • There is extensive coverage on carrier oils (like jojoba, coconut oil, fractionated coconut oil etc.) and emulsifiers (like Castile soap and aloe vera oil). He also shares that liquid stevia is a solubilizer (this one intrigues me)
  • All the wonderful recipes – from home cleaning to personal care products to many products for addressing specific health conditions like aching muscles, wounds, candida, dandruff and much more. Here are a few ways he shares how peppermint essential oil, one of my favorites, can help: as a digestive aid (I use it topically in coconut oil, together with lavender at night and love it!), to ease muscle tension, to clear sinuses, as a potential solution to antibiotic-resistant infections (I’ve used lavender and lemongrass when I had a boil but wasn’t aware peppermint had similar properties), to give you focus and provide an energy pick-up and much more.  Here is one application for your hair/scalp:

A few drops of peppermint essential oil included in your shampoo and conditioner will tingle your scalp and wake your senses. As a bonus, peppermint’s antiseptic properties can also help prevent or remove both lice and dandruff.

 

  • Here is a safe and effective bathroom cleaner recipe from the book – and it smells wonderful! I love the added bonus of getting a mood boost while cleaning!

    Tea Tree Citrus Bathroom Cleaner

    The star of this blend is orange essential oil, which is a known mood booster. You’ll be happier even though you’re stuck cleaning the bathroom!

    1 tablespoons Dr. Bronner’s liquid castile soap

    2 tablespoons baking soda

    20 drops tea tree essential oil

    15 drops orange or lemon essential oil (or 7 drops of each)

    15 drops lemon eucalyptus or lemon myrtle essential oil

    2 cups distilled water

    Supplies: 32 oz spray bottle, preferably glass

    1. Combine the liquid soap, baking soda and essential oils in the spray bottle and mix well.
    2. Pour in the water and shake well
    3. Use as you would any other bathroom cleaner. Shake before use.

    Elsewhere in the book, Dr. Z writes about how eucalyptus is highly antimicrobial, helping to clear surfaces of potential germs (and says you can use regular eucalyptus in the above recipe too).

  • There is a big focus on women’s health and anxiety and depression, so it’s perfect for you. The recipes for PMS, perimenopause and menopause are fabulous – with help for anxiety, depression, insomnia, vaginal dryness and much more. Here is one where clary sage helped with depression (anxiety was not assessed but we know high cortisol and low serotonin impacts both anxiety and depression)

Clary sage offers antidepressant effects as described in a 2014 study that was conducted on twenty-two women in Korea. The trial measured neurotransmitter levels found in blood samples of menopausal women and discovered that, by simply inhaling clary sage oil, levels of the stress hormone cortisol dropped considerably and serotonin levels were elevated. The result was an overall improvement in depression symptoms.

  • There is an entire chapter on essential oils for fertility, pregnancy and postpartum
  • Photosensitivity is explained and he lists all the oils that fall into this category (such as bergamot and expressed lemon)

Some essential oils can increase the photosensitivity of your skin. For example, chemicals in the citrus family such as bergapten are notable for their phototoxic effects. When bergapten is left on the skin and then exposed to the sun, it can amplify the effect of UV rays, potentially causing sunburn and leading to sunspots. Some people just decide not to use any bergapten-heavy oils topically, but simply avoiding the sun after use (for example, by applying them at night) is sufficient.

  • He addresses the concerns about lavender and tea tree being estrogenic and explaining why they are not (I get this question a lot!)
  • Plenty of oils and recipes for digestive support like a SIBO blend of a 1:1:1 ratio of caraway, lavender and neroli (which I am very interested in exploring further)

As you can see, this book is comprehensive, research-based, practical and I would even say pretty exciting and fun! Here is the official blurb about the book:

Eric Zielinski, D.C., host of the Essential Oils Revolution summits, offers a soup-to-nuts guide to mastering essential oils for vibrant health and well-being, featuring dozens of recipes and formulations for restful sleep, reduced inflammation, balanced hormones, and more.

Achieving true health is not an easy task. For many people, it might be easier to pop a pill or push aside lingering discomfort in favor of finishing everything on your to-do list. In The Healing Power of Essential Oils, Eric Zielinski, D.C. shows readers how to make their health a priority with the life-changing benefits of essential oils. Essential oils are the natural solution to everything from anxiety and depression to deep-seated inflammation.

For beginners, Dr. Z teaches everything you need to know to get started, including the top seven oils you should stock from Day 1 and the commonly used techniques and tools. He illustrates daily practices you can follow to enjoy the properties of essential oils, including a five-minute devotional using frankincense and neroli to set you up for a productive and stress-free day, and a simple bedtime routine harnessing the soporific effects of lavender.

Backed by extensive research, Dr. Z also supplies essential oil blends that promote hormone balance, reduced inflammation, improved digestion, increased immunity, and so much more. You’ll be armed with over 150 recipes for every health need, and a special section on women’s health includes dozens of formulations for PMS, fertility, pregnancy, candida, and menopause. Even those well-versed in essential oils will benefit from this thorough approach. With your newfound knowledge, you can begin tailoring an essential oils practice to your unique pain points and lifestyle right away – and start experiencing amazing results.

Grab a copy from your nearest bookstore or online store such as Amazon (this is my amazon affiliate link)

Be sure to grab the bonus gifts here after you’ve purchased the book

And let us know what you think and some of your favorite recipes and how they have helped you!

Filed Under: Books, Essential oils Tagged With: anxiety, clary sage, cortisol, depression, Dr. Z, eric zielinski, essential oils, lavender, menopause, The Healing Power of Essential Oils

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