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Too much GABA causes a tingling niacin-like flush sensation (in the brain and body). It’s awful and very uncomfortable!

February 18, 2022 By Trudy Scott 39 Comments

too much gaba

GABA, used as an amino acid, helps to raise GABA levels and ease physical tension-type anxiety. There are many misunderstandings on the best and most effective ways to use GABA and this can lead to unpleasant symptoms. One common thing I see is that too much GABA causes the brain and body to react with a tingling niacin-like flush sensation that is very uncomfortable and often described as awful.

Too many people stop using GABA for this reason. And then they lose out on the wonderful calming benefits of this amino acid. Some folks actually push through and continue with the unpleasant tingling sensation because they don’t know better and because they are also getting some of the calming benefits of GABA (I share an example of this below). Neither situation is ideal.

I recently received a GABA question on the blog on this very topic. It was from a licensed acupuncturist in California, USA (let’s call her Dr. M):

When I used to take GABA for my stress, my body/brain reacted with a tingling sensation.

It was so awkward and uncomfortable.

I thought it was only me, but when I prescribed GABA to my patients, they also felt the same sensations.

Can you tell me why this reaction occurred?

Thank you so much for your generosity and deep research.

Because this is such a common question that I get, I’m sharing it and my responses to use it as a teaching opportunity.

Too much GABA can cause this uncomfortable tingling niacin-like flush or sensation

I responded sharing that it can happen when too much GABA is used or if GABA is not needed. I typically hear of this happening when 500mg to 750mg is used to start. It’s also often described as a niacin-like flush. With GABA, 125mg is a typical starting dose and it’s always used as a sublingual or capsule opened onto the tongue. We slowly go up from there based on symptoms and the final dose is unique to each person’s needs. You may end up using 500mg or more but it’s a slow approach to get there.

I asked Dr. M to share which product/s she used, the dosing and let me know if she does better with a lower dose.

As expected she was using too high a dose (and hadn’t done a trial of a lower dose). She responded with this feedback:

The GABA I used for me and my patients is from Pure Encapsulations. This GABA contains 700 mg per capsule, which may be too much for the start.

Which brand would you recommend for practitioner use?

I responded by confirming that 700 mg GABA is way too much to start for most people.

What product and how much to use instead of 700 mg GABA

I like the Pure Encapsulations product but I actually feel the companies are partially at fault for having such high dose products, stating “1 capsule daily, between meals, or as directed by a health professional” on the label, and not educating practitioners and consumers about this issue.

With a product like this I have clients open up the capsule and start with 125 mg GABA powder on the tongue and increase from there as needed.

I also shared the other GABA products I use in case she would prefer to try something like the Source Naturals GABA Calm product I frequently use with clients.

This is a lozenge that contains 125 mg GABA, 5 mg magnesium, 50 mg glycine, 25 mg tyrosine and 20 mg taurine. This is my most popular and most effective form of GABA I use with my clients. [Note: this product is a lozenge with 125mg GABA and is not to be confused with the Source Naturals, GABA Calm Mind, 750 mg tablets]

I’m waiting for feedback from her to hear how using less of the 700 mg GABA (opened up and divided out) or how using another GABA product works for her and her patients.

I do appreciate Dr. M for asking a tough question like this and being open to me sharing so everyone gets to learn.

Where did Dr. M learn about GABA and some resources for additional practitioner education

I did ask Dr. M where she learned about using GABA and if the recommendation was to use a high dose like this. I’m genuinely curious to know so I can help guide further education in the use of GABA.

Of course, I encouraged her to get my book “The Antianxiety Food Solution” and read the chapter on the amino acids. And to consider signing up for the amino acid training for practitioners. There are many nuances and best practices when using the amino acids. And it’s an opportunity to interact with me and other practitioners who are also using the amino acids.

If you’re a practitioner, I’m hoping this question, my feedback and these resources are helpful for you.

Similar niacin-like flush experienced by Holly

As mentioned above this is a very common issue because most GABA products are 500mg and up and folks hear how amazing GABA is for physical anxiety and use a high dose without understanding they need to start low and use only what they need.

I shared my discussion with Dr. M in a Facebook post and Holly responded with what happened to her when she switched from GABA Calm (which has 125 mg GABA) to a 750 mg GABA product:

I experienced the niacin-like flush when I tried to go from GABA Calm [mostly dissolved in my mouth] to a pill form and didn’t realize the dosage would be way too high all at one time. The pill was 750 mg GABA [and swallowed with food], so it wasn’t going to work well anyway.

The flush lasted about 15-20 minutes. It was awful. I was sure I was going to throw up every time.

It took me a couple of weeks to figure out the cause.  My therapist recommended your website and book and those helped me understand when to take it and why it would help.

When I eliminated the 750 mg GABA  pill the symptoms completely went away.

Now I stick to GABA Calm. I take one in the morning and one before bed and sometimes one midday.

I appreciate Holly for sharing and I’m glad her and her therapist figured it out.

Resources if you are new to using GABA as a supplement

If you are new to using the the amino acids GABA as supplements, here is the Amino Acids Mood Questionnaire from The Antianxiety Food Solution (you can see the low GABA and other low neurotransmitter symptoms)

In case you’re new to the low GABA-type of anxiety, with low GABA levels you may experience physical-tension and stiff-and-tense-muscles, panic attacks, more physical tension in certain settings like public speaking or driving. You will often have the need to self-medicate to calm down, often with alcohol but sometimes with carbs and sugary foods.

Insomnia can also be caused by low GABA and you’ll experience physical tension in bed at night rather than the ruminating thoughts which is the low serotonin type of insomnia (although it’s not uncommon to experience both.) GABA also helps with muscle spasms and pain relief when muscles are tight.

If you suspect low levels of GABA or low serotonin and do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the team you or your loved one is working with.

The book doesn’t include product names (per the publisher’s request) so this blog, The Antianxiety Food Solution Amino Acid and Pyroluria Supplements, lists the GABA products that I use with my individual clients and those in my group programs.

Get guidance in the GABA QuickStart Program

If you don’t feel comfortable reading my book, doing the low GABA symptoms questionnaire and doing trials of GABA on your own, you can get guidance from me in the GABA Quickstart Program.

We have an active and engaged community in the private Facebook group and there are 2 live Q & A calls with me.

One of the recent participants shared this lightbulb moment after starting with GABA Calm in the day and then shifting to 250 mg GABA at night only:

Listening to the GABA Quickstart made me realize something about the Source Naturals GABA Calm with the bit of tyrosine. I bought the NOW GABA powder and last night took 250mg (1/8 tsp and I have tiny measuring spoons) and woke up great.

I think I found my dose of GABA and I don’t think after my trial I’m a GABA in the day girl.

Have you used a high dose of GABA to start (or switched to a higher dose like Holly did) and experienced this unpleasant niacin-like flush?

How much caused this tingling sensation for you and how unpleasant was it? Did you push through and continue using the high dose? Or did you figure it out and use less? How long did it take you to figure it out?

Maybe you quit using GABA because of something like this – do you now feel inspired to try again?

If you’ve had success with using GABA please do share too.

If you’re a practitioner where did you learn about using GABA and was the recommendation was to use a high dose like 500 mg or 750 mg to start?

Feel free to ask your questions here too.

Be sure to share which product you used, how much you used and if you have low GABA symptoms.

Filed Under: Anxiety, Diet, GABA Tagged With: anxiety, bizarre, GABA, grain-free, horrible, intrusive thoughts, keto, Ketogenic, LCHF, low carb/high fat diet, microbiome, nutritional psychiatry, OCD, paleo, postpartum, serotonin, tryptophan, zinc

A lifetime of horrible and bizarre intrusive thoughts eliminated by a low carb/high fat diet (not as strict as keto) – a case study and research

February 11, 2022 By Trudy Scott 16 Comments

intrusive thoughts and low carb high fat diet

Intrusive thoughts are a symptom of anxiety, are more common than you’d expect and it’s not just you who experiences them. Today’s case study illustrates the power of diet: a low carb/high fat diet (not as strict as keto) completely eliminated a lifetime of horrible and bizarre intrusive thoughts for one woman. Read examples of her actual intrusive thoughts below and check out the supporting research and other case studies.

Ruthie suffered from intrusive thoughts as a child and most of her adult life, and assumed everyone did too. As a child, she would share some of her bizarre thoughts with other children, and they would stare at her and tell their parents. Her own parents became extremely concerned believing she might do one of these bizarre things. Her husband would sometimes look at her in horror when she asked certain questions. As an adult, she was told she was “unusual in a nice sort of way-haha!” This is how she described some of her intrusive thoughts:

They took the form of either myself or family members doing horrible/bizzare things or I would get in the car to go someplace and imagine one of the other drivers on the road doing something bizarre and my mind would follow it right through to the end result of what the individual caused to happen. I would arrive at my destination not remembering any part of my drive, my mind was so busy.

She goes on to share some of her postpartum experience with intrusive thoughts:

Everyone thought I had postpartum depression with my first child but it was the intrusive thoughts that had put me into a panic regarding her care. It was wonderful when a therapist told me it was the intrusive thought component of OCD and I could put a name to it.

It was the greatest delight of my life, when both children grew bigger and stronger than me so I knew, even though I knew I would never hurt them, they had the chance to defend themselves!

For her, eating high fat/low carb has eliminated her lifetime of intrusive thoughts:

Fast forward to discovering the low carb/high fat (LCHF) eating plan (not as strict as keto) and my intrusive thoughts have been gone for almost 2 years now (unless I become overtired).

It is a simply horrid disorder to have. I am just glad now it is well known but it really upsets me that it is being treated with dangerous psychotropic drugs that can do more harm than good when diet changes could be the solution.

I asked if she had ever used GABA or tryptophan (covered in part 1) or any other nutrients during any of the really bad periods and if any of it had helped. She shared that tryptophan gave her dreams that were too vivid and “by the time I was aware of GABA as a possibility, I had changed my diet and my problems had basically been resolved.”

She also confirmed her LCHF diet is predominantly gluten/grain free except the occasional splurge. I suspect these splurges may contribute to her feeling overtired and factor into her intrusive thoughts showing up again.

These are powerful results and I’m thrilled for her. I also appreciate her willingness to share and for allowing me to include her story.

A low carb/high fat (LCHF) / Ketogenic diet study

Most of the LCHF diet research focuses on weight loss and improvement of metabolic markers for conditions like diabetes. However, there is some promising new research on mental health.

This 2020 paper is one example – Ketogenic Diet: A Dietary Modification as an Anxiolytic Approach?

Diets with low amounts of carbohydrate consumption (low-carb) seem promising both for weight mass optimization among mentally ill patients and for their possible anxiolytic effect.

A diet is characterized as being low-carb high-fat (LCHF) when fat comprises >70% of the daily calorie consumption, with sugars [or carbs] being 5–15%, and the rest of the calorie intake being made up of proteins.

This paper discusses anxiety and the role of serotonin, GABA/glutamate imbalance, hypothalamic-pituitary-adrenal axis and elevated cortisol, inflammation and oxidative stress, the microbiome and leaky gut.

It also covers some ways LCHF diets may reduce anxiety: via impacts on the microbiome (with GABA being produced by good bacteria in the gut), by reducing inflammation and oxidative stress, and by providing omega-3 fatty acids and healthy oils (such as olive oil). The inclusion of real whole foods (i.e. no processed junk foods) with quality protein and zinc-rich foods such as oysters, low glycemic index carbohydrates and leafy greens as a source of magnesium, all contribute too.

The authors do mention canola oil which I do not recommend. And contrary to their mention of egg whites, I recommend the entire egg.

Their conclusion includes these statements:

In our mind, the LCHF diet is a promising, well-accepted diet regimen which has an impact on anxiety disorders…

The evidence mentioned in this paper should encourage psychiatrists to recommend LCHF diets as advice somewhere between psychotherapy and pharmacology, or as an add-on to those two.

And I’ll add this: let’s consider LCHF instead of psychotherapy and pharmacology. As you heard Ruthie share above and as you’ll read below, diet changes alone can have profound effects.

Dietary changes alone can be profound for many folks

I’ve blogged extensively about diet in the past: ketogenic diets, the omnivore or Paleo diet and grain-free diets. Diet provides the foundation of any anxiety nutritional program but many people don’t realize or acknowledge that dietary changes alone can be profound for many folks.

I’ll typically hear something like this: “My anxiety [or depression or intrusive thoughts] are too severe for only diet to make a difference. I’m someone who really does need medication.”

As you’ll see below, diet alone can make a huge difference and is often the only thing that needs to change:

  • Ketogenic diet: reductions in auditory hallucinations and delusions, better mood and energy, and weight loss

Two schizoaffective patients of Dr. Chris Palmer, a psychiatrist from Harvard’s McLean Hospital in Belmont, Massachusetts, tried a ketogenic diet for weight loss. As well as losing weight, they experienced reductions in auditory hallucinations and delusions, had a better mood and had more energy. I review the 2018 study and offer my insights in this blog.

  • An “omnivore” like diet or Paleo diet is associated with reduced anxiety and depression

This type of diet is also referred to as a cave-man type of diet. Even though this 2018 study was only showing associations and not a cause-and-effect, it’s still very encouraging to see new research in the field of nutritional psychiatry, further supporting the results we see in clinical practice.

  • Paleo and grain free diets: anxiety and depression success stories

I share many success stories in this blog. Here is an example from one woman: “Three days after I stopped eating grains, my chronic depression lifted and has never returned (it’s three years later now).”

  • Integrative Medicine Approach to Pediatric Obsessive-Compulsive Disorder and Anxiety

I write about a 2016 study where gluten was found to be the cause of a childhood case of obsessive-compulsive disorder (OCD). Intrusive thoughts are common with OCD and a gluten-free diet (and some other interventions) led to a “marked reduction of OCD symptoms and anxiety along with marked improvement of social behavior and school work.”

This is a small selection of many similar articles on the blog.

Other nutritional and hormonal solutions

This blog is part 2 of my deeper dive into intrusive thoughts and as a follow-on to part 1 where I cover low GABA, low serotonin, low zinc, low vitamin B6 (and pyroluria) and hormone imbalances as root causes for some individuals.

  • Many people “did not realize intrusive thoughts were a ‘thing’ a symptom of something” and thought it’s just something that happens to them
  • A definition of intrusive thoughts from The Anxiety and Depression Association of America and the fact that “Unwanted intrusive thoughts can be very explicit, and many people are ashamed and worried about them, and therefore keep them secret.”
  • The article that inspired these blogs on intrusive thoughts: The Debilitating Anxiety Symptom No One Ever Talks About
  • How to address low GABA, low serotonin, pyroluria (low zinc & vitamin B6) and hormone imbalances as possible causes (and examples from folks with these causes, plus supporting research)

As I mentioned in part 1, my purpose is to share actual examples from real people so you can see how varied these intrusive thoughts can be. And recognize that they are a thing and that you are not alone if you experience them.

And, of course, to create awareness that there are nutritional solutions.

My book as a resource if you are new to nutritional psychiatry

If you are new to nutritional psychiatry, do read this blog: Nutritional medicine in modern psychiatry: position statement by ISNPR.

If you do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading the chapters on diet, sugar and blood sugar control, gluten and grains, and caffeine/alcohol so you have the foundation in place. Who knows, it may be the only changes you need to make to eliminate your intrusive thoughts and other anxiety symptoms!

Be sure to share it with the health team you or your loved one is working with.

If you are new to using the the amino acids GABA or 5-HTP/tryptophan as supplements, I cover this and pyroluria in part 1: Intrusive thoughts are a thing with anxiety: low GABA, low serotonin, pyroluria (low zinc & vitamin B6) and hormone imbalances as possible causes. Be sure to read the many comments and especially Kimberly’s feedback – she combined everything in the above blog and saw wonderful results.

As I mentioned in part 1, let’s talk about intrusive thoughts so we don’t have to feel alone and so we can find solutions. And share your success with nutritional solutions when something works for you. Share it with your friends, your health practitioner, researchers and on this blog.

Did you know intrusive thoughts are a thing, or did you think it was just you? And what kind of intrusive thoughts have you had?

Are you surprised that a LCHF/keto or similar diet could have such a profound impact?

Has a dietary approach alone helped you eliminate your intrusive thoughts or other anxiety symptoms?  Or has diet, in conjunction with amino acids such as GABA and tryptophan helped?

What else has helped eliminate or reduce your unwanted intrusive thoughts?

Feel free to ask your questions here too.

Filed Under: Anxiety, Diet, GABA Tagged With: anxiety, bizarre, GABA, grain-free, horrible, intrusive thoughts, keto, Ketogenic, LCHF, low carb/high fat diet, microbiome, nutritional psychiatry, OCD, paleo, postpartum, serotonin, tryptophan, zinc

Food: What the Heck Should I Cook by Dr. Mark Hyman

October 23, 2019 By Trudy Scott 2 Comments

Dr. Mark Hyman proudly shares this about his new recipe book – Food: What the Heck Should I Cook

This cookbook is a beautiful work of art—full color, lots of recipe pictures, and over 100 delicious and healthy pegan recipes. The book features tasty recipes with delicious whole food ingredients.

Everything in the cookbook meets my Pegan Diet guidelines, which means all the recipes are gluten-free, dairy-free, refined sugar-free, and nutrient-dense. Whether you or someone in your household is Paleo, vegetarian, vegan, keto, pescatarian—it’s got super satisfying meals you’ll all love and can enjoy together.

Plus, I talk about how to create a conscious kitchen – which includes how I choose the ingredients I cook with as well as the safest cooking tools.

And he shares more about why he wrote this new cookbook – a companion book to Food: What the Heck Should I Eat – in the book trailer video.

Here are few recipes from the book to get you inspired and cooking: Blushing Beet Soup, Feel-Good Pesto Steak Salad, Almond Chicken Skewers with Green Beans and Flourless Protein Power Bread.

blushing beet dip

pesto steak salad

almond chicken skewers

protein power break

Here are a few of the many other recipes: Superfood Smoothie Bowl, Green Shakshuka, Crispy Carrot Fries with Pesto, Coriander Salmon with Coconut-Tomato Salsa, Toasted Sage Butternut Pizza, Lemon-Berry Rose Cream Cake, and Chocolate-Almond Sandwich Cookies.

He calls this recipe book  “one of my most exciting personal projects to date, one that I hope will be something you can use to create better health while sharing great times with the people you love.”

Learn more about the book here

Buy your copy on Amazon here (my Amazon link).

I hope it inspires you to create delicious healthy real food meals to eat and enjoy with your loved ones! And let us know which recipes you decide to make.

Filed Under: Books Tagged With: cooking, dairy-free, Dr. Mark Hyman, food, Food: What the Heck Should I Cook, gluten-free, nutrient-dense, paleo, Pegan, recipe book, recipes, refined sugar-free, vegetarian

An “omnivore” like diet or Paleo diet is associated with reduced anxiety and depression

March 23, 2018 By Trudy Scott 12 Comments

A new study published last month, Do patterns of nutrient intake predict self-reported anxiety, depression and psychological distress in adults? SEPAHAN study, reports that

An “omnivore” like diet high in amino acids, cobalamin, zinc, phosphorus, saturated fat, cholesterol and pantothenic acid is associated with reduced psychological disorders.

This was a cross-sectional study, meaning it was a type of observational study design where the outcome and the exposures in the study participants are measured at the same time. The aim was to find an association (rather than causal relationship) between patterns of nutrients intake and psychological disorders such as anxiety and depression.

The study authors had 3846 Iranian adults between 18 and 55 of age complete questionnaires in order to assess their diets and nutrient patterns, as well as psychological factors including anxiety, depression, and overall health in general. This group comprised 1712 males and 2134 females.

The study results

After calculating the daily intakes of 57 nutrients (including individual amino acids,

starch, dietary fiber, simple sugars, different fatty acids, vitamins, minerals, and bioactive substances), 3 nutrient patterns were identified:

1) the “omnivore” pattern

high in individual amino acids, cobalamin, zinc, phosphorus, saturated fatty acids, cholesterol and pantothenic acid

in both women and men, with pyridoxine (vitamin B6) high in men only

2) the “grains and dairy” pattern

high in thiamin, folate, selenium, iron, starch, maltose, betaine, calcium, riboflavin, and niacin

and low in the following

mono-unsaturated fats, vitamin E and polyunsaturated fats

3) “fruits and vegetables” pattern

high in copper, vitamin C, glucose, fructose, potassium, dietary fiber, sucrose, vitamin A, magnesium and vitamin K.

These are the associations that were observed after adjusting for confounding factors:

  • Men in the top tertile of the omnivore nutrient pattern had lower anxietyand depression scores than those in the bottom tertile
  • Women in the top tertile of the omnivore nutrient pattern had better overall poor health scores than those in the bottom tertile and had lower odds of psychological distress, such as anxiety and depression.

This type of diet is also referred to as a Paleo or cave-man type of diet. Even though this study was only showing associations and not a cause-and-effect, it’s still very encouraging to see new research in the field of nutritional psychiatry, further supporting the results we see in clinical practice.

What are the mechanisms?

The high amino acids provide the building blocks for the production of our feel-good neurotransmitters such as serotonin, GABA, dopamine and endorphins, with zinc being a key co-factor for making these brain chemicals. The authors share some of the mechanisms for the association in the discussion section of the paper:

Dietary protein intake and also individual amino acid status have been linked to psychological status in previously published studies. For instance, methionine in the form of S-adenosyl-L-methionine, tryptophan and serine were inversely associated to depression. Lysine, arginine, beta-alanine, tryptophan and tyrosine have been shown to have anxiolytic effects. As amino acids are important precursors for neurotransmitters; they might affect psychological condition. Important neurotransmitters like dopamine and serotonin are made from amino acids tyrosine and tryptophan, respectively.

Pantothenic acid is a B vitamin that is key for stress and adrenal health. Low levels of B12 or cobalamin can be associated with both anxiety and depression, as well as fatigue. Both zinc and B12 are common deficiencies, and more so in vegetarian and vegan diets. The authors discuss some possible zinc mechanisms:

  • zinc has antidepressant-like activities such as up-regulation of the expression of brain derived neurotrophic factor (BDNF) gene
  • zinc is an antagonist of the glutamate/N-methyl-D-aspartate (NMDA) receptor

Seeing saturated fat and high cholesterol mentioned in favorable terms in a study – both of which are needed for a healthy brain and for good blood sugar control – is always exciting. The authors discuss these possible mechanisms:

low serum total cholesterol may increase the risk of depression and suicide attempts. It is hypothesized that low cholesterol intake might cause a depressed central serotonergic activity which in turn leads to depression.

Here is my addition to the discussion: in our interview on a prior Anxiety Summit, Dr. Kurt Woeller and I discuss the link between low cholesterol and low oxytocin and the role this plays in anxiety, social bonding and depression.

One area I’m a little confused about is the findings on pyridoxine (vitamin B6). They report it was high only in men in the omnivore group, and not in women. As they report, vitamin B6 is also a key co-factor in the serotonin-tryptophan pathway and we know it’s important for alleviating anxiety- related PMS symptoms in women. It’s mentioned in the concluding paragraph for playing a role in the association for both men and women and yet it is not mentioned in the abstract. I’ll report back as I find out more.

Here are some actual real-life results from someone eating this way

I blogged about anxiety and depression success stories on Paleo and grain free diets around this time last year. I shared Andrea’s feedback about her diet-mood results with a grain-free and high fat diet:

I happened upon a fat loss diet that had me cut out grains, most dairy, and sugar while focusing on mostly meat, fish, fats from nature such as butter, olive, and coconut oils. Nuts, seeds, and legumes were allowed too. These rules made it so I had to avoid processed foods. There was one day a week of eating anything.

Within 6 weeks I was shocked that I got much much more than fat loss. My depression, anxiety, mood swings, sleep issues and all but one pesky health symptom disappeared. I was stronger, faster, and felt energy I never remember having.

Have you found benefits with an omnivore or Paleo diet? Less anxiety and depression? Better overall health? More energy? Better sleep?

If you’re a practitioner have you found this approach works with your clients/patients?

Filed Under: Diet Tagged With: amino acids, anxiety, cave-man diet, depression, health, omnivore, paleo, psychological distress, saturated fats, zinc

Paleo and grain free diets: anxiety and depression success stories

March 31, 2017 By Trudy Scott 13 Comments

I recently reached out to my community to hear your diet-depression or diet-anxiety success stories in anticipation of the new SMILES diet depression trial, published last month and which I covered in a blog post last week. In that post I promised to share some real-life success stories on how diet changed people’s lives for the better!

I also shared that everyone who responded with success stories was following a more “evolved” diet than those who participated in the SMILES trial (the first randomized controlled diet depression study where ONE THIRD of the dietary intervention group saw improvements in their depression symptoms by switching from processed/junk food to real food with no specific dietary restrictions!).

What do I mean by a more evolved diet? Each of them was eating a real foods or traditional non-processed diet that was gluten-free, mostly or all grain-free and various permutations of the Paleo or cave-main diet.

The anxiety and depression success stories

Alice from Cape Town shared this about banting, a Paleo-type dietary approach that does include dairy products and has been popularized in South Africa by Professor Tim Noakes:

Three days after I stopped eating grains, my chronic depression lifted and has never returned (it’s three years later now). I had been a vegetarian most of my life, discovered in my early 50s that I was gluten intolerant, went off grains, started banting (Cape Town craze!) and have never felt better. Gut, mood, bones, energy, skin … all better!

Andrea shared this about her diet-mood results, also with a grain-free and high fat diet:

I happened upon a fat loss diet that had me cut out grains, most dairy, and sugar while focusing on mostly meat, fish, fats from nature such as butter, olive, and coconut oils. Nuts, seeds, and legumes were allowed too. These rules made it so I had to avoid processed foods. There was one day a week of eating anything.

Within 6 weeks I was shocked that I got much much more than fat loss. My depression, anxiety, mood swings, sleep issues and all but one pesky health symptom was left disappeared. I was stronger, faster, and felt energy I never remember having.

Holly shared how she healed severe depression and anxiety by changing her diet:

Over the course of a year and a half, I was given 10 different psychiatric diagnoses and cycled through 10 different medications. I discovered the healing power of diet completely by accident, and it changed my life. I now live with no diagnoses and no symptoms.

I started with the Whole30 (strict paleo), then went paleo, dabbled with a ketogenic approach, and now I eat a modified paleo diet, with some rice and goat dairy.

Krysti shared how diet reduced her severe mood swings and panic attacks:

I was dx with bipolar at 18 years old. Suffered panic attacks and the random severe mood swings that made absolutely no sense. I was sad for days to weeks only to be followed with unrealistic overly-exuberant highs where I had the energy of a toddler on sugar and the signature grandiose thoughts that I could simultaneously fly and conquer the world and do all the things! For a day. Then the next day felt numb. And resorted back to “cutting” just to feel something. I never cut for attention. In fact not even my closest friends knew I did it. It was for me and I hid it.

…my oldest sister introduced me to Paleo. I was soon dx celiac, cut out grains and have been med and *mostly* mood swing/manic free ever since. No panic attacks. I have never felt more emotionally stable. Even through the death of my youngest sister and big life events, my emotions have been that of a normal person. Explicable. Expected. Level. No extremes.

You can read their entire inspiring diet-depression stories and other ones in the comments on this blog.

Thanks to Alice, Andrea, Holly and Krysti for sharing your wonderful and very hopeful stories! It warms my heart and I know it inspires my community!  

And here is my story again:

For me it was anxiety and panic attacks that resolved when I made dietary and other nutritional and lifestyle changes.   I had been eating a vegetarian diet for a few years and I suspect the non-organic/GMO processed soy products (soy milk, soy yogurt, soy “butter” etc) were a big issue for me and damaged my gut.  When I added back quality animal protein (grass-fed red meat, wild fish, pastured eggs and chicken), switched to organic produce, added healthy fats and removed gluten my mood improved dramatically.  Now I eat a combination of a Paleo/SCD /low FODMAPS/low oxalate diet. 

During the severe anxiety and panic attacks I also needed additional support in the way of the targeted amino acids GABA (this was a life-saver and stopped the panic attacks in a few days) and tryptophan, plus zinc, vitamin B6, evening primrose oil, a good multi and B complex and adrenal support.  I still continue with some of these basic nutrients today.

My health issues have been complex as I’ve also had to deal with heavy metals, poor gut health and much more so I had what I call “a perfect storm” and yet diet has had such a huge impact for me!

Getting off medications

Lead researcher Professor Felice Jacka was quoted in an ABC article saying this in response to the SMILES trial:

people suffering from depression should not replace therapy and drug treatments with the Mediterranean diet.

Based on my experience working with clients and feedback I receive on the blog, finding the ideal diet and addressing all nutritional deficiencies often allows my clients to work with their doctors on eliminating all their depression and antianxiety medications. Other medications also go by the wayside: pain meds, high blood pressure meds, allergy meds, reflux meds etc.

What is Paleo?

I had the pleasure of hearing Australian Chef Pete Evans at an all-day Sydney event earlier this year, in celebration of the launch of his new book The Complete Gut Health Cookbook, with co-author Dr. Helen Padarin. He is a big time Paleo advocate and this is what he said on stage at the start of his presentation and wonderful day of cooking demos:

Paleo is basically a meat and 3 vegetables – it’s that simple!

To expand on this a bit…this means quality animal proteins like grass-fed red meat, wild fish, pastured eggs and chickens, organic vegetables (typically lower carb) and fruit, soaked nuts (if tolerated), bone broths, fermented vegetables and broths, and health fats like coconut and avocado. Many in the Paleo community say no to dairy and butter but I do find that some of my clients do fine with small amounts and some people do better with fermented dairy like kefir and yogurt or goat/sheep and even camel milk rather than cow’s milk.

I also got to meet both Pete and Helen at the book signing – they are both wonderful and very down-to-earth!

Meeting the famous (and very down-to-earth) Chef Pete Evans at the book signing

Can you imagine my surprise when Pete invited me on to stage to welcome me to Australia and share a bit about my work with diet and anxiety!?

Here is a 5 minute clip of me on stage with Pete and Helen where we talk about:

  • How what we eat has a direct impact on our brains and how we feel
  • How our gut bacteria make some of our brain chemicals like serotonin and GABA when we consume fermented foods [and other foods rich in amino acids and organic produce]
  • The term “psychobiotics” coined by Dr. Ted Dinan ie. good bacteria that improve our mood
  • Kelly Brogan’s wonderful work around depression and diet and medication tapering, and her great book A Mind of Your Own
  • How quickly can diet lead to anxiety and depression symptoms improving and allowing you to get off medications? …biochemical individuality, diet alone, addressing gut health, adding fermented foods, addressing low zinc and other root causes, looking at gene defects
  • Real food, liver, rooibos tea, herbs
  • My story of anxiety and panic attacks and changing from a vegetarian diet to a modified Paleo diet
  • The Anxiety Summit and my book The Antianxiety Food Solution as resources

 

As you’ve read with these success stories and heard me say on Pete’s stage, many people can do it with diet alone (even if their anxiety is very severe), many need additional nutritional support, and many need the targeted individual amino acids to get immediate relief from their anxiety or depression while they are looking for all their root causes. Many also need the amino acids to break their gluten and sugar addictions. But making the dietary changes are the foundation!

Stay tuned for more about Pete Evans, some of his recipes and gut healing protocols and the unfortunate grilling he’s been getting in the Australian media for advocating a Paleo diet! In the meantime, I will say that all his books come highly recommended!

In case you’re wondering about the research on the Paleo diet, while we don’t have a study that’s looking directly at anxiety and depression, we do have these papers on the overall benefits of a Paleolithic diet:

  • January 2017: Benefits of a Paleolithic diet with and without supervised exercise on fat mass, insulin sensitivity, and glycemic control: a randomized controlled trial in individuals with type 2 diabetes
  • June 2016: Paleolithic and Mediterranean Diet Pattern Scores Are Inversely Associated with Biomarkers of Inflammation and Oxidative Balance in Adults
  • January 2016: Cutting through the Paleo hype: The evidence for the Palaeolithic diet

And in this paper co-authored by Professor Felice Jacka – Nutritional psychiatry research: an emerging discipline and its intersection with global urbanization, environmental challenges and the evolutionary mismatch, they mention

a potential evolutionary mismatch between our ancestral past (Paleolithic, Neolithic) and the contemporary nutritional environment.

We do, of course, have many studies supporting a diet-mood connection:

  • Anxiety and Hypoglycemia Symptoms Improve with Diet Modification
  • Western diet is associated with a smaller left hippocampus and anxiety
  • Integrative Medicine Approach to Pediatric Obsessive-Compulsive Disorder and Anxiety

  • Reduced anxiety in forensic inpatients – long-term intervention with Atlantic salmon

And Professor Felice Jacka shared this during our interview on The Anxiety Summit: The Research – Food to prevent and treat anxiety and depression? 

One of the hypotheses that I had during the Ph.D. was that increased intake of animal foods would be toxic and would be associated with more mental disorders.

This did not turn out to be the case: In our study, out of every single dietary food grouping that I looked at including vegetables, fruits, salads, beans, etc the strongest correlate of mental health was red meat intake [grass-fed red meat of course.]

Consistently, women who have less than the recommended intake of red meat seem to be in an increased risk for common mental disorders [like anxiety and depression] and bipolar disorder.

She was referring to the results of her Ph.D. paper that was published in the American Journal of Psychiatry in 2010: “Association of Western and Traditional Diets with Depression and Anxiety in Women.”

Have you changed your diet to a Paleo way of eating and observed a reduction or elimination of anxiety or depression? Was a dietary change enough or did you need to address brain chemical imbalances and other nutritional deficiencies too?

If you’re a practitioner, have you seen results like this with your clients or patients?

 

Filed Under: Antianxiety, Antianxiety Food Solution, Paleo Tagged With: anxiety, depression, felice jacka, grain-free, grains, paleo, Pete Evans, red meat, vegetables

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