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GABA

GABA the calming amino acid: common questions I get asked

By Trudy Scott 53 Comments

gaba common questions

GABA is the main calming neurotransmitter and the amino acid GABA is wonderful for boosting low levels of GABA and thereby eliminating physical anxiety, tension, panic attacks and overwhelm. It can also help reduce pain and insomnia. I get asked great questions about GABA on the blog all the time and here are some common questions that you may find helpful.

GABA, new found peace and do I need more at different times of my cycle?

I have taken your recommendations I heard you speak about on your most recent Anxiety Summit about GABA – and have been experiencing some new found peace that I thought was forever lost to me. It has been truly wonderful! Thank you!

I have a question – in your experience, have you found that different levels/amounts of GABA were needed at different times in a woman’s cycle? I would be interested to know if there is any research or observational data related to GABA receptors and how they are affected by the hormonal ups and downs – AND how to respond to that with supplementation and/or food and lifestyle adjustments.

Here is my response: I love this – new found peace!  GABA is closely related to progesterone which we know fluctuates during our cycles so for some people mirroring this can help even more i.e. some of my clients find it’s beneficial to take extra GABA just before their period or earlier if their anxiety symptoms increase. I have them use their symptoms to guide increasing and decreasing their GABA.

Here are two studies that support this connection in women with premenstrual dysphoric disorder and women who are perimenopausal:

Increasing evidence has suggested that the GABAergic neurotransmitter system is involved in the pathogenesis of premenstrual dysphoric disorder (PMDD) … dysregulation of the amino acid neurotransmitter system may be an important neurobiological mechanism in the pathogenesis of PMDD

failure of the GABAA receptor to regulate overall GABA-ergic tone in the face of shifting levels of these neurosteroids may induce HPA axis dysfunction, thereby increasing sensitivity to stress and generating greater vulnerability to depression.

I have not seen any research on GABA supplementation in the second half of the cycle (luteal phase) but recently blogged about how tryptophan helps PMS symptoms of anxiety, tension and irritability.

I write about GABA, pyroluria and low cholesterol in this same blog.

A question about GABA, tyrosine and other neurotransmitter imbalances

GABA Calm – who can take this as it has tyrosine? Can someone with low serotonin or high serotonin take this? Or is it best to take straight GABA for those who are not meant to take tyrosine. Can a person who has low GABA have other neurotransmission issues i.e. high dopamine or low serotonin?

Here is my response: The GABA Calm (by Source Naturals)  has a very small amount of tyrosine so unless it’s contraindicated it’s the one I use with most of my clients. You would not use it if you have melanoma or Grave disease and would watch carefully if you have high blood pressure or migraines. You can read all the amino acid precautions here.

Many people with low GABA levels may also have signs of the other low neurotransmitters. The best way to figure this out is to do the amino acid questionnaire and do a trial of the relevant amino acid.

You mention high serotonin and high dopamine so I’m guessing you have had the urinary neurotransmitter test done. I’d like to share that I don’t place much value in urinary neurotransmitter testing and prefer to have my clients do a trial.

A question about migraines and getting a red flush with GABA

I’ve had lifelong migraines along with anxiety and depression that have waxed and waned. I’d like to try the aminos and curious if you have any special recommendations or contraindications for migraine with aura.

I’ve tried GABA in the past but ended up with a red flush like a niacin flush. Any ideas on why that might have happened? I suspect maybe the dose was too high. I wanted to try the GABA Calm since it has a low dose of GABA but I’m not sure if tyrosine is a potential migraine trigger.

Would love a little enlightenment on all the above so I’m not so gun shy and doing more harm than good.

Here is my response: Tyrosine is an issue with migraines and I avoid it with clients with a lifelong history of them especially if they are still having them (please see the precautions). If they choose to try a product with tyrosine they simply stop if a migraine is triggered.

Too much GABA can cause a flush and breathlessness. I find this to be the case when 500mg or 750 mg and above is used to start. I have my clients start on the 125mg found in GABA Calm and slowly build up.

When GABA Calm can’t be taken, opening a capsule of a GABA-only product is what we do. You can find the GABA/theanine products I use here. Some of my clients are pixie dust people and need 1/10th of capsule or 200mg GABA so starting low is important for everyone but even more so if you have had a reaction in the past.

I blogged about the large variation in GABA dosing here.

Don’t forget that 1000mg of vitamin C can help to negate the effects of an amino acid. Hopefully this will give you more confidence to do a trial.

A question about insomnia with SIBO/candida and GABA and 5-HTP

What do you do or recommend for people with SIBO/ yeast Overgrowth and can’t sleep well as a result (can’t stay asleep)? I have played with 5-HTP and GABA in the past, but they seemed to have the opposite effect (caused more insomnia). I have read that with overgrowth issues, these products can travel down the wrong metabolic pathway. Have you found this in your clients?

Here is my response: The amino acids will only help with sleep if neurotransmitters are low i.e. GABA will help if GABA is low, 5-HTP or tryptophan will help if serotonin is low. There is actually a great study that shows that a combination of GABA and 5-HTP may help insomnia.

If they are making sleep worse I’d wonder if doses are too high, and I’d look at quality and fillers. I’d also do a trial with tryptophan as 5-HTP can be an issue with high cortisol and this could impact sleep.

Tryptophan can convert to quinolinic acid without the correct co-factors, so taking zinc, curcumin and B vitamins etc. are important. Some people find the Lidtke Tryptophan Complete to be more helpful that the 500mg Tryptophan if they don’t have the co-factors as part of their current protocol.

It goes without saying that foods that make SIBO and candida symptoms worse should be avoided as they may cause bloating and would keep you awake.

With insomnia I’d also look at the following: low blood sugar, parasites, high cortisol, gluten, being on the computer, prior or current benzodiazepine prescriptions.

Resources if you are new to using the amino acids as supplements

If you are new to using any of the amino acids as supplements, here is the Amino Acids Mood Questionnaire from The Antianxiety Food Solution (you can see all the symptoms of neurotransmitter imbalances).

If you suspect low levels of any of the neurotransmitters and do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the practitioner/health team you or your loved one is working with.

There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, blood sugar control, sugar cravings, self-medicating with alcohol and more.

The book doesn’t include product names (per the publisher’s request) so this blog, The Antianxiety Food Solution Amino Acid and Pyroluria Supplements, lists the amino acids that I use with my individual clients and those in my group programs.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA Quickstart Program (if you have low GABA symptoms). This is a paid online/virtual group program where you get my guidance and community support. There are many moms in the program who are having much success with their kids.

If you are a practitioner, join us in The Balancing Neurotransmitters: the Fundamentals program. This is also a paid online/virtual program with an opportunity to interact with me and other practitioners who are also using the amino acids.

With much appreciation for these women for sharing their stories and allowing me to provide my insights for them and you. We all have much to learn from each other.

Can you relate to any of these questions and have some of these GABA adjustments helped you?

If you have questions please share them here too.

(Most recent updates: June 24, 2022)

Yoga increases brain GABA levels and reduces anxiety

By Trudy Scott 8 Comments

triangle-pose

In a 2007 study published by the Division of Psychiatry at the Boston University School of Medicine – Yoga Asana sessions increase brain GABA levels: a pilot study – researchers had 8 yoga practitioners complete a 60-minute yoga session and 11 comparison subjects complete a 60-minute reading session.

The study objective was to compare changes in brain levels of gamma-aminobutyric acid (GABA) – our calming neurotransmitter – in those completing the 60-minute yoga session and in those reading.

These were the results that were reported:

There was a 27% increase in GABA levels in the yoga practitioner group after the yoga session but no change in the comparison subject group after the reading session.

And here is the conclusion the authors reached:

These findings demonstrate that in experienced yoga practitioners, brain GABA levels increase after a session of yoga. This suggests that the practice of yoga should be explored as a treatment for disorders with low GABA levels such as depression and anxiety disorders. Future studies should compare yoga to other forms of exercise to help determine whether yoga or exercise alone can alter GABA levels.

In this study, GABA levels were measured with magnetic resonance spectroscopic imaging (MRS/MRSI) before and after the yoga and reading sessions. If you really want to know how yoga improves your anxiety you could do the GABA section of the amino acid questionnaire and rate your before and after symptoms:  

  • Anxiety and feeling overwhelmed or stressed
  • Feeling worried or fearful
  • Panic attacks
  • Unable to relax or loosen up
  • Stiff or tense muscles
  • Feeling stressed and burned-out
  • Craving carbs, alcohol, or drugs for relaxation and calming

The above study looked at experienced yoga practitioners but there is so much research on the many benefits of yoga for everyone and for many conditions. Here is a small sampling of some other studies that include anxiety as well as depression, stress, hormonal imbalances and sleep issues:

If you’ve never done yoga or if you haven’t been doing it for a while this blog will hopefully give you the motivation to start a yoga practice or get back into it.

You may ask: how do I get started?

The important thing is to find the joy in doing it so I encourage you to try different classes until you find one you love. I love Iyengar yoga but it’s not for everyone (it can be seen as too slow for some people.) Here is a yoga DVD for more advanced Iyengar yoga students: Iyengar Yoga with Gabriella.

If you already do yoga this will confirm what you already likely know. Please share what yoga you enjoy, how often you practice and how it leaves you feeling.

If you’re a health practitioner, please share if yoga is something you recommend to your clients or patients.

GABA-consuming bacteria discovered: Evtepia gabavorous

By Trudy Scott 25 Comments

bacteria

New bacteria that consumes GABA, the main calming neurotransmitter, has been discovered. It has provisionally been named KLE1738 Evtepia gabavorous (vorous means “eating”).

This new discovery was presented at the recent American Society for Microbiology conference in Boston in the Microbial Mind Control session.

Here is the entire abstract: Gaba Modulating Bacteria of the Human Gut Microbiome:

The gut microbiome affects many different diseases, and has been recently linked to human mental health. The microbiome community is diverse, but 50-80% of its diversity remains uncultured. We previously reported that uncultured bacteria from the marine environment require growth factors from neighboring species, and by using co-culture, we could cultivate novel diversity. In the present study, we used a similar co-culture approach to grow bacteria from humans stool samples. KLE1738, a “Most-Wanted” member of the human gut microbiome only known by its 16S rDNA signature, was found to require the presence of Bacteroides fragilis KLE1758 for growth. Using bio-assay driven purification of B. fragilis KLE1758 supernatant, γ-aminobutyric acid (GABA), the major inhibitory neurotransmitter of the central nervous system, was identified as the growth factor for KLE1738. We found no other tested compound but GABA supported the growth of KLE1738, and genomic analysis suggests an unusual metabolism focused on consuming GABA. Due to this unique growth requirement, we provisionally name KLE1738 Evtepia gabavorous. Using growth of E. gabalyticus as an indicator, we then identified novel GABA producing bacteria from the gut microbiome. Reduced levels of GABA are associated with depression, and we found fewer GABA producers in a human cohort of depressed individuals. By modulating the level of GABA, microbial producers and consumers of this neurotransmitter may be influencing host behavior.

If you’re anxious and especially if you have physical anxiety, it’s worth considering if low GABA is an issue and addressing your anxiety by trying to raise your GABA levels by taking GABA as a supplement, with lifestyle activities like yoga sessions, by eating a real whole foods traditional diet and by addressing gut health.

There is much research supporting the gut-brain connection and how imbalances of the microbiome i.e. intestinal dysbiosis, can contribute to:

Could Evtepia gabavorous be a factor in all of the above? It’s too soon to know but I expect we’ll know more as more research is completed.

If you’re looking for more information on GABA and the gut:

We certainly appreciate Postdoctoral Research Associate, Phillip Strandwitz and his team for the work they are doing. Strandwitz shares this on his bio:

my work has led me to focus on the gut-microbe-brain axis, specifically microbes able to modulate levels of neurotransmitters

I reached out to I asked him why he is interested this area of research and he shared this with me:

I think mental health is an incredible burden to society and there is not nearly enough spotlight nor funding to understand and treat these issues. I believe the microbiome is involved (at least to some capacity), and I’m passionate about trying to understand this involvement to create novel therapies to help those in need. I’m also a strong supporter of diet/lifestyle changes for better cognition!

How wonderful is this!

It’s early days and right now we can only speculate but it may be worth to considering if the presence of Evtepia gabavorous may be a reason why some individuals continue to need to take GABA supplements long-term to keep anxiety at bay. It also gives us additional reasons to focus on addressing gut health and boosting good bacteria to help to reduce the need for ongoing GABA supplementation.

As soon as the paper is published, I’ll have more details to share. In the meantime, enjoy the fascination and wonderment of the human body and our microbiome.

Please share if you have signs of low GABA and have you been taking GABA supplements long-term? Do you also have gut issues and dysbiosis too (based on stool testing)?

PS. So many of you contacted me with a link to this preliminary research so I’d just like to say thanks!

World Benzodiazepine Awareness Day – say NO to Benzodiazepines for anxiety!

By Trudy Scott 17 Comments

world benzo awareness day july 11 2016

Today, July 11th, is  World Benzodiazepine Awareness Day

This date was designated in recognition of Prof. Heather Ashton’s significant contributions to the benzodiazepine cause over so many decades; together with all of the help she has given to so many people around the world.

In honor of World Benzodiazepine Awareness Day, also called W-BAD I’ve decided to re-release a webinar I did last year: Say NO to Benzodiazepines for anxiety  [CLICK THIS LINK TO FIND THE WEBINAR]

say no-to-benzo

Here is an excerpt of the overview from: Say NO to benzodiazepines for anxiety! 

Benzodiazepines are a class of psychoactive drugs that work by enhancing the effect of the calming neurotransmitter GABA, and are used to treat anxiety, insomnia, pain, muscle spasms and a range of other conditions. They are widely prescribed, particularly among elderly patients and may even be used off-label with children with autism.

Use of this medication is very controversial.  We know long term use leads to tolerance, dependence, and many adverse psychological effects and even physical effects. Short term use is generally considered safe but even using them for 2 – 4 weeks can lead to problems for certain individuals.

This presentation provides an overview of benzodiazepines; when they are used; who they are prescribed to; details about tolerance, dependence, and the many adverse effects; how to taper, including nutritional support during the taper; what to do instead of saying yes to a benzodiazepine prescription in the first place; and additional resources.

Here is one of the benzo stories I share in the webinar:

world benzo awareness day story

 

We know that some individuals are much more affected than others when it comes to tolerance and withdrawal.  Here are some other possible factors that may affect tolerance and withdrawal:

world benzo awareness day liver enzymes

During season 4 of the Anxiety Summit, Lisa Bloomquist talked about Antibiotic Induced Anxiety – How Fluoroquinolone Antibiotics Induce Psychiatric Illness Symptoms.   During this interview she shared how:

People who have gone through benzodiazepine withdrawal before should never take a fluoroquinolone because essentially it can throw people right back into the benzo withdrawal – because it has very similar effects on people’s GABA’s receptors as what happens when people go through benzodiazepine withdrawal. 

I would love to see a survey of people who have experienced adverse effects when using benzodiazepines as prescribed or when tapering. Could these be some of the contributing factors?

  • Taking Valium/ diazepam and have the CYP2C19 polymorphism (about 10-20% of Western populations are defective in genes of the CYP liver enzyme superfamily)
  • Taking Xanax/ alprazolam and have CYP3A5 polymorphism (about 10-20% of Western populations are defective in genes of the CYP liver enzyme superfamily)
  • Taking any benzodiazepine and also
    • Taking oral contraceptives
    • Taking a course of antibiotics
    • Taking a course of one of the fluoroquinolone antibiotics
    • On an SSRI prescription
    • Taking a course of antifungal medications
    • Drinking alcohol on a regular basis
    • On an opioid such as oxycodone
    • Drinking grapefruit juice on a regular basis

For withdrawal/tapering, the best resource I know of is Benzo.org.uk which contains the Ashton Manual. You will need to educate yourself and your doctor and/or find a doctor willing to help you with the adjusted prescription. It does need to be done very very very slowly.

Finding a good support group like Benzobuddies.org  is very helpful for many of my clients. Just be aware that this group and some of the other support groups say no to any supplements during the taper process. I find it to be very individualized and have many clients that see great benefit by using GABA, tryptophan, zinc, magnesium and other nutrients. (You can read more about this here: Anxiety and the amino acids overview)

That being said some people tapering can only tolerate very low amounts of the amino acids (like a dab or pinch from a capsule) and some can’t tolerate any supplements and do better with essential oils, yoga, light therapy and dietary changes.

You can find more information on World Benzodiazepine Awareness Day on Benzo Case: Raising Awareness about Benzodiazepine Drugs  (widely prescribed for anxiety, stress, sleep, pain and much more…) and additional stories on the World Benzo Awareness facebook page.

World Benzodiazepine Awareness Day was conceived by the acting Chair Barry Halsam, former Chair of Oldham TRANX, and jointly organized by Wayne Douglas, founder of benzo.case.com / benzo-case-japan.com

Please read share so your loved ones are informed and can say NO to benzos!  

If you have experienced adverse effects when taking or tapering from benzodiazepines I’d love some feedback on the above possible contributing factors.

 

Sleep improvement: Oral intake of GABA and Apocynum venetum leaf extract

By Trudy Scott 17 Comments

sleep-improvement

I’ve blogged about the Sleep promoting effects of combined GABA and 5-HTP. There is another combination of nutrients that has been shown to help with sleep: GABA and the herb Apocynum venetum leaf extract.

In this 2015 paper: The Improvement of Sleep by Oral Intake of GABA and Apocynum venetum Leaf Extract

The electroencephalogram (EEG) test revealed that oral administration of GABA (100 mg) and [Apocynum venetum Leaf Extract] AVLE (50 mg) had beneficial effects on sleep.

In this study they found that GABA helps people to fall asleep quickly and Apocynum venetum Leaf Extract induces deep sleep, and that they work well when taken together.

The authors conclude that both GABA and Apocynum venetum leaf extract:

can be regarded as safe and appropriate for daily intake in order to improve the quality of sleep.

Earlier this year I heard Dr. Peter Bongiorno present at the Integrative Healthcare Symposium and one of the herbs he covered was Apocynum venetum leaf extract for depression. Since this was new to me, I invited him to share about this herb on the recent Anxiety Summit: Serotonin and anxiety: tryptophan, 5-HTP, serotonin syndrome and medication tapers

I also briefly mentioned the above GABA/Apocynum venetum leaf extract study in my talk on the recent Anxiety Summit – GABA: Blood brain barrier controversy, concerns, best forms and how to do a trial for eliminating anxiety

I find that many of my clients with anxiety also have sleep problems and GABA is often helpful if their sleep issues are related to low GABA levels, often manifesting as physical tension.

One of the signs of low serotonin, in addition to anxiety and worry, is insomnia and I find tryptophan (and sometimes 5-HTP) to be very helpful for many clients too. I’ll often have someone use both GABA and tryptophan (or GABA and 5-HTP) and the combination seems to be a good one.

I have not yet used Apocynum venetum leaf extract alone with clients or in combination with GABA and look forward to learning more. Have you have tried it alone or in combination with GABA? Have you used it with clients?

The Anxiety Summit – GABA: Blood brain barrier controversy, concerns, best forms and how to do a trial for eliminating anxiety

By Trudy Scott 106 Comments

Trudy Scott_GABA_Anxiety4

Trudy Scott, Food Mood Expert and Nutritionist, author of The Antianxiety Food Solution. presents during the Anxiety Summit Season 4.

GABA: Blood brain barrier controversy, concerns, best forms and how to do a trial for eliminating anxiety

  • Dispelling the blood brain barrier and the leaky brain myths
  • The newest research on GABA effectiveness
  • The best forms of GABA and why I have concerns about phenibut
  • Results from clients and feedback from practitioners using GABA
  • How to do a trial for the best results in eliminating anxiety

Here are some snippets from my presentation:

Worry and anxiety can be a result of low GABA and also low serotonin, so you may check off anxiety in both sections. Low GABA tends to result in a more physical anxiety, while low serotonin tends to result in more anxiety in the head and ruminating thoughts etc

With low GABA you have physical anxiety

  • Anxiety and feeling overwhelmed or stressed
  • Feeling worried or fearful
  • Panic attacks
  • Unable to relax or loosen up
  • Stiff or tense muscles
  • Feeling stressed and burned-out
  • Craving carbs, alcohol, or drugs for relaxation and calming

The targeted use of individual amino acid supplements like GABA will balance brain chemistry to alleviate anxiety, fear, worry, panic attacks, and feeling stressed or overwhelmed. They can also be helpful in addressing other problems that contribute to or exacerbate anxiety, such as sugar cravings and addictions. In addition, they can help with depression and insomnia, which often co-occur with anxiety.

Here is the amino acid questionnaire with all 5 sections including GABA

Here is the blog that discusses urinary neurotransmitter testing and why I don’t use it

Here are the list of amino acid precautions 

the main precaution with GABA is low blood pressure but I have yet to see it as an issue, liver/kidney issues – watch, GABA has not been studied in pregnancy or breastfeeding

Many individuals tapering from benzodiazepines find using GABA and other nutrients help the taper while others can’t tolerate GABA and other supplements.  If you’re new to the ill-effects of benzos do watch this webinar I did for Hawthorn University last year: Say NO to Benzos

The blood brain barrier controversy and the fact that so many people say GABA only works if you have a leaky brain

Does a GABA supplement have to cross the blood brain barrier to be effective? A nutrition seminar I have been to, said it does not and GABA supplements are ineffective

The 1960 paper published by Eugene Roberts, the scientist who discovered GABA mentions the failure of GABA to penetrate the blood-brain barrier readily:  Metabolic and Neurophysiological Roles of GABA

The 2015 zonulin intestinal permeability/leaky gut and possible blood brain barrier disruption paper: Gluten Psychosis: Confirmation of a New Clinical Entity

Zonulin is a tight junction modulator that is released by the small intestine mucosa upon gluten stimulation. Interestingly the zonulin receptor, identified as the precursor for haptoglobin-2, has been found in the human brain. Overexpression of zonulin (aka haptoglobin-2) could be involved in the blood brain barrier disruption similarly to the role that zonulin plays in increasing intestinal permeability.

NY Times article: Could Alzheimer’s Stem From Infections?

A virus, fungus or bacterium gets into the brain, passing through a membrane — the blood-brain barrier — that becomes leaky as people age

GABA – other possible mechanisms of action:

The microbiome and the bidirectional gut brain communication: Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

Is the blood brain barrier more dynamic than assumed? A 2015 study discusses this Oral GABA supplementation allows better prioritizing of planned actions: new research

In the literature, there are controversial findings about GABA entering the brain through the blood brain barrier (BBB). The BBB is a tightly sealed layer of cerebral endothelial cells that form continuous tight junctions and prevent most solutes from entering the brain on the basis of size, charge, and lipid solubility. However … recent studies have demonstrated that the BBB is much more dynamic than assumed in the past, and some passage of solutes can occur by transcytosis, carrier-mediated transport, or simple diffusion of hydrophobic substances.

GABA’s relaxing effect may be due to peripheral effects rather than the effect on/in the brain. Here is an excerpt from this paper: GABA-receptors in peripheral tissues

GABA and its receptors are found in a wide range of peripheral tissues, including parts of the peripheral nervous system, endocrine, and non-neural tissues such as smooth muscle and the female reproductive system

The possible peripheral effects are also mentioned in this paper –  Psychological stress-reducing effect of chocolate enriched with gamma-aminobutyric acid (GABA) in humans: assessment of stress using heart rate variability and salivary chromogranin A

it has been considered that GABA may act on the peripheral nervous system of the digestive organs and not the central nervous system

The newest research on the mechanism of GABA was published just last year in October 2015 – Neurotransmitters as food supplements: the effects of GABA on brain and behavior

There is some evidence in favor of a calming effect of GABA food supplements, but most of this evidence was reported by researchers with a potential conflict of interest. We suggest that any veridical effects of GABA food supplements on brain and cognition might be exerted through BBB passage or, more indirectly, via an effect on the enteric nervous system. We conclude that the mechanism of action of GABA food supplements is far from clear, and that further work is needed to establish the behavioral effects of GABA. 

Here is other GABA research I mentioned:

I voiced concerns about how with phenibut physical dependence can develop and withdrawal symptoms can be similar to benzodiazepines

And how gabapentin withdrawal tends to mimic some of the same withdrawal symptoms associated with benzodiazepine withdrawal

Here is the blog post: how to do an amino acid trial for anxiety

I get valuable feedback about GABA’s effectiveness from other practitioners. Here are a few (and more here):

Dr. Josh Friedman, integrative psychotherapist uses amino acids and other nutritional approaches in his practice:

[GABA] is definitely something I use. I am not a biochemist, so I actually don’t really know whether it crosses the blood/brain barrier, nor do I care actually. The first question should be, is it harmful? Are any of these things going to cause harm? And the answer with all the amino acids are no, they’re not going to cause harm, especially when compared to psychiatric medicines. The second question is, does it work? Is it helpful for our patients that we see in our practice?

Jonathan Prousky, ND, MSc, editor of the Journal of Orthomolecular Medicine and author of Anxiety: Orthomolecular Diagnosis and Treatment shares this in our season 2 interview: Tapering off psychiatric drugs so they do not ruin your life 

I have found GABA to be invariably helpful and I don’t really know exactly how GABA works but I know it to be very, very safe and, to me, that is fundamentally important. It’s not associated with any withdrawal, with any tolerance, with any habituation, so people can try it without a lot of concern.

And it seems fitting to end with a quote from my mentor Julia Ross

On a scale of zero to ten, zero is not an unrealistic goal when it comes to anxiety.  It’s really the human potential and GABA gives us access to it.

And some feedback from real people who’ve used GABA (more here)

Dee likes the instant calm from a product that contains 500mg GABA and 200mg Theanine:

I have taken Xanax in the past for panic attacks. My functional medicine doctor suggested this product as I wanted a natural product. I was amazed how it works just like the Xanax did – instant calm feeling within 10 mins of taking 2 capsules. I use them as needed when I am having heightened stress and anxiety.

Melissa likes a product that contains GABA, taurine, glycine, inositol, niacin and vitamin B6

After my first panic attack I thankfully found Julia Ross’s work. I began taking 250 mg GABA every night. That really helped! Now a few years later I don’t need it every day, and I take a half pill during my cycle anxiety – more like uneasiness and over worried now, just as needed. I then heard you speak Trudy and share more info, bought your book, and put into place supportive lifestyle changes, and I have my life back. GABA is a great supplement for some of us!

Gina chewed two 100mg pharma GABA tablets and said this:

It changed my life in minutes! Take it every day now. No more hopelessness!

Do the amino acid questionnaire, review the precautions and do a GABA trial and let us know how it worked for you? If you’re a practitioner I’d love feedback too.

I’d also love to hear if you notice any difference opening a capsule or using something like GABA Calm instead of swallowing a capsule.

Here’s to hope and calm!

If you are not already registered for the Anxiety Summit you can get live access to the speakers of the day here: www.theAnxietySummit.com

Missed this interview or can’t listen live? Or want this and the other great interviews for your learning library? Purchase the MP3s or MP3s + transcripts and listen when it suits you.

You can find your purchasing options here.: Anxiety Summit Season 1, Anxiety Summit Season 2, Anxiety Summit Season 3, and Anxiety Summit Season 4.