New research published in November 2015: Study of GABA in Healthy Volunteers: Pharmacokinetics and Pharmacodynamics shows potential benefits for diabetes:
Our data show that GABA is rapidly absorbed and tolerated in human beings; its endocrine effects, exemplified by increasing islet hormonal secretion, suggest potential therapeutic benefits for diabetes.
This is very interesting because they conclude that GABA is rapidly absorbed and tolerated in human beings. This is very encouraging because we often hear that taking oral GABA will have no impact.
Here are additional details about the study:
Twelve subjects were subjected to an open-labeled, three-period trial involving sequential oral administration of placebo, 2g GABA once, and 2g GABA three times/day for 7 days, with a 7-day washout between each period.
Based on my work with anxious clients, even using 2g of GABA once a day is considered a high dose, especially if they don’t have low GABA levels. Because of this I’m not surprised at some of the side-effects:
Subjects with repeated dosing showed an elevated incidence of minor adverse events in comparison to placebo or the single dosing period, most notably transient discomforts such as dizziness and sore throat.
I have my anxious clients do a GABA trial in order to figure out their ideal dose. I recommend starting with around 125 mg GABA a few times a day.
In this 2012 study: Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks study participants used only 100mg of GABA and saw mental stress reduction effects within 30 minutes.
Anxiety is more prevalent in diabetes than we realize and it’s something I seldom hear discussed:
- More than 25% of the diabetic women in this 2015 study done in India reported high levels of anxiety
- This 2015 study found that severe anxiety in early pregnancy is more frequent in Brazilian women with diabetes
- In this 2015 Australian study half of the women with diabetes experienced an anxiety disorder
What disease affects EVERY other American and one in four kids? Type 2 diabetes or pre-diabetes. Type 2 diabetes in America has tripled since the 1980s, and researchers estimate one in three Americans will have diabetes by mid-century. More than one-third of American adults are obese.
I’d like to highlight two of his 7 excellent steps: Pull the Sugar and Control Stress Levels.
GABA is an amino acid that makes both of these steps much easier to achieve! GABA stops sugar cravings so you don’t need to use willpower. And GABA ends physical anxiety so you don’t have to manage it. Make the food changes, take the nutrients and do the yoga Dr. Hyman recommends, but why not add GABA too?
You can read more about Melissa’s success with GABA in this blog: GABA for ending sugar cravings (and anxiety and insomnia)
So here we have the amino amazing acid GABA that:
- we know reduces and often eliminates sugar cravings completely
- calms the anxious mind and reduces stress within 5 to 30 minutes
- has the potential of offering therapeutic benefits for diabetes
Be sure to check out the other 5 tips that Dr. Hyman offers and do share if you have seen benefits from GABA – for anxiety/stress and sugar cravings. Do let us know if you also have/had diabetes and noticed any improvements in your blood sugar labs.
If you’re a practitioner and use GABA with your patients/clients with diabetes, please share too.