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de-stress

Does GABA offer gut protection after drinking alcohol?

September 22, 2017 By Trudy Scott 2 Comments

A paper published earlier this year has us asking the question: will oral GABA supplementation offer gut protection in humans who drink too much alcohol? It’s too soon to know but the results from the animal study leave me spell-bound by this calming amino acid yet again!

The paper, Gastroprotective effect of gamma-aminobutyric acid on ethanol-induced gastric mucosal injury

aimed to investigate the gastroprotective effect of gamma-aminobutyric acid (GABA) on ethanol-induced gastric mucosal injury and gastric epithelial cells injury [in rats].

Ethanol or alcohol is known to damage the gut and the study was carried out on rats given GABA and then ethanol.

It was also tested using the human gastric epithelial cell line GES-1 (more here on how human cell lines are commonly used in research) which was incubated with GABA and then treated with ethanol to induce cell injury.

The use of GABA prior to treatment with ethanol

showed that GABA pretreatment significantly reduced gastric ulcer index in a dose-dependent manner.

Administration with GABA could not only remarkably restrain oxidative stress by increase of superoxide dismutase, catalase activities and decrease of malondialdehyde content in gastric tissue and cells, but also significantly reduced pro-inflammatory factors activities (interleukin-6 and tumor necrosis factor α) in gastric tissue.

These studies clearly provided evidence that GABA had a considerable gastroprotective effect on ethanol-induced gastric mucosal injury and gastric epithelial cells injury. The underlying mechanism of mitigating lesions may be ascribed to the improvement of anti-inflammatory and anti-oxidant status as well as the increases of PGE2 [prostaglandin E2] and NO [nitric oxide] levels.

In summary, the use of GABA shows the potential for less ulcers, less oxidative damage, less inflammation in the gut, and gastroprotective properties after alcohol consumption. Human studies will show if oral GABA supplementation offers gut protection in those who drink too much alcohol.

Many social drinkers are not connecting their drinking to stress

We are a stressed society and this leads a great deal of “social” drinking. Many social drinkers are not connecting their drinking to stress and their need to self-medicate and de-stress.

As I found when I posted new study this on facebook – Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline – many social drinkers also get upset when you point out research like this because they don’t want to have to give it up. This CNN article, Moderate drinking may alter brain, summarizes the study and reports that the

moderate group was drinking about 14 to 21 units of alcohol per week, or about a medium glass of wine each night, plus a little extra on the weekends.

What is so interesting is that this very same calming amino acid, GABA, when used to address low GABA levels can help reduce your need to self-medicate or self-soothe with alcohol (or sugar/carbs). Don’t forget, with low GABA levels, you’ll also experience physical anxiety, stiff and tense muscles, overwhelm and panic attacks. I recently blogged about GABA here: GABA for the physical-tension and stiff-and-tense-muscles type of anxiety

Of course, I’d recommend using GABA supplements to address the low GABA and prevent so much “social” drinking that may damage to the gut (i.e. addressing the root cause as always), rather than using GABA so you can prevent gut damage when you do drink.

If you are a big “social” drinker and choose the latter (use GABA to prevent gut damage when you do drink) be warned, you’ll feel calmer and less stressed and very likely reduce your desire and need for a drink!

My blog mentions “social” drinking because of the paper about moderate alcohol consumption above but all this could be equally applicable to heavy drinkers and alcoholics too.

In summary, oral GABA can achieve the following:

  • help you quit alcohol and not feel deprived and having to use willpower
  • leave you feeling calm and stress-free with no need to self-medicate with alcohol
  • heal damage caused to your gut if you do indulge once in awhile (based on projections from the above research)

Have you noticed that GABA reduces your need to drink alcohol?

Have you noticed any improvements in gut health since using GABA?

Filed Under: Anxiety, GABA, Stress Tagged With: alcohol, anxiety, de-stress, GABA, gastroprotective, gut damage, self-medicate, stress

Smile and laugh to de-stress, calm down and boost your mood

June 14, 2013 By Trudy Scott 15 Comments

 laughter

My biggest stress-relief and mood-boosting tip is to smile and laugh! It is one of the many things I encourage my clients to do! And I personally love a good comedy and opportunity to smile and laugh! I almost feel like I need my “fix” of laughter by the end of the day. It really relaxes me, boosts my mood and helps me sleep better.

I was further inspired to make a commitment to laugh each day when I read all the research supporting the many and varied health benefits. Many days I’ll just take a break and engage in spontaneous laughter for no reason at all – just the act of laughing leaves me feeling SO good. I do food-mood presentations around the country and typically end my talks with a laugher session with the audience! It’s a great hit and they leave my talk feeling great!

A 2012 research paper in Physiological Science actually showed that if you smile, you feel less stressed. Also in a 1999 study, “Personality traits such as warmth, calmness, extroversion, and low anxiety were closely related to an attractive smile.”

Laughter falls into a similar category as smiling and is wonderful for improving mood and reducing anxiety and stress and pain. This 2012 paper. showed that laughter “is associated with feelings of wellbeing” and improved mood, likely related to “the release of endorphins.” The release of endorphins also reduced pain levels.

Recent research also shows that the “combination of a laughter and exercise program might have physiological and psychological health benefits for the elderly”. Laughter may also “be an effective strategy to motivate the elderly to participate in physical activity.”

Laughter is actually good for the heart as indicated by the title of a 2009 paper: “The effect of mirthful laughter on the human cardiovascular system.”

Here are some things to make you chuckle: a fun post I did awhile ago about a wonderfully funny and romantic blog called The Musings of a Romantic Comedy Girl and a video of a laughing baby. Enjoy!

And of course, the added bonus: if you eat foods that raise serotonin (like grass-fed read meat and wild fish like salmon), you’ll be happier and more inclined to smile too – and feel even less anxious and less stressed. Tryptophan or 5-HTP will help boost your serotonin levels and are wonderful if you do have low serotonin. You can check for low serotonin levels using this Amino Acids Mood Questionnaire from The Antianxiety Food Solution. 

Filed Under: Antianxiety Food Solution, Anxiety and panic, Depression, Food and mood, Joy and happiness, Pain, Stress Tagged With: Antianxiety Food Solution, anxiety, calm, de-stress, happy, laughter, pain, smiling, stress

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