• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar

everywomanover29 blog

Food, Mood and Women's Health – Be your healthiest, look and feel great!

  • Blog
  • About
  • Services
  • Store
  • Resources
  • Testimonials
  • The Book
  • Contact
  • Search this site

headache

D-phenylalanine (DPA) for easing both physical pain (tooth pain) and emotional pain over the holidays

January 5, 2024 By Trudy Scott 33 Comments

dpa for pain

Today I share how the amino acid D-phenylalanine (DPA), used as a supplement multiple times a day, and opened on to my tongue, eased both the physical tooth pain I experienced for 14 days and the emotional pain I was feeling over the holidays.

In this blog I share more about DPA and endorphins when it comes to pain – both physical and emotional. I also share two DPA products I recommend, product label confusion and more about how DPA differs from DLPA (DL-phenylalanine). I am often asked this question and even long time users of DLPA are sometimes surprised to learn how different DPA is. As always, I like to share some research and other related blogs on the topic. Here is my recent and very positive personal experience with DPA, a firm favorite of mine:

I’m just back from the dentist – my crown was re-cemented and I’m a happy camper now. It popped off just before Christmas and I had to wait until now! There was a tiny cavity beneath the crown which is why I was having daily pain.

Thank goodness I always have DPA (the amino acid d-phenylananine) on hand. I gravitate to it for pain relief – sports injuries like muscle sprains, the rare headache and this time for tooth/jaw pain.

I opened a DPA onto my tongue as soon as I could feel the dull ache start and the pain relief lasted a few hours. It works by boosting endorphins to provide pain relief – kind of like acupuncture.  I call it “powdered acupuncture”.

Some days I used 3-4 and one day I needed 6. Taking one before bed was wonderful.

I also got bonus benefits for emotional well-being over the holidays. It’s the first Christmas without my darling mom and I really needed the endorphin boost to help with the emotional pain.

The DPA product I used was Doctor’s best (details below) and I opened up the 500 mg capsule onto my tongue each time I needed pain relief.

The number of capsules I needed seemed to vary by how much chewing I was doing (for example, I had more pain after a steak meal vs smoked salmon) and what I was eating or drinking (for example, I had more pain after drinking something cold). I simply used a DPA capsule when the dull pain started, making sure it was away from protein (not always but most of the time).

UPDATE: Sept 13, 2024
DPA has come to my rescue yet again and this time the tooth pain has been very severe. I initially suspected it was the crown again but when I got into the dentist an xray confirmed an abscess at the tip of one of the roots.

It’s a first for me and I’ve never experienced a toothache like this. The pain ramps up from zero to 10 (with 10 being most severe) in a matter of seconds. The only thing that helps right now is DPA. I’m opening a capsule every few hours and have even had to use it every 30 mins when it’s really severe like after drinking or eating something. It brings to pain down to a 3 in a matter of minutes.

I’ve figured out that using a straw to drink liquids helps a ton. I’m also  using a soft ice-pack a few times a day too. Strangely it’s worse just before bed, after I take my bedtime supplements. I need the DPA and ice-pack but fortunately I have no pain through the night.  Thank goodness for that!

I’m also using a herbal antibiotic and herbal mouth swish from my naturopath while I get a second opinion, learn about my options, and decide next steps.

All this has solidified DPA as my go-to supplement for pain relief.

One of the DPA products I recommend: Doctor’s Best D-Phenylalanine

There are not many d-phenylalanine/DPA products available but of those I have two that I recommend: Doctor’s Best D-Phenylalanine and Lidtke Endorphigen. Both contain 500 mg DPA but the labels can be confusing at first – at least until you’re familiar with them.

Also, this amino acid, DPA, is not to be confused with docosapentaenoic acid (also abbreviated as DPA), an omega-3 fatty acid similar to eicosapentaenoic acid (EPA).

dr's best dpa

Here is the Doctor’s Best D-Phenylalanine description:

Doctor’s Best D-phenylalanine is a non-protein amino acid that acts as an inhibiting agent to enzymes that degrade enkephalins, naturally occurring peptides in the body that metabolize endorphins. Endorphins are neurotransmitters that play a key role in the function of the nervous system and are associated with feelings of pleasure. By limiting production of enzymes that break down endorphins, the supplement can help support a healthy mood and normal functioning of the nervous system.

  • Helps support healthy mood
  • Helps support endorphin metabolism
  • Help support neurotransmitter function

This is the actual product that I used over the past 2 weeks and have used it on and off as needed for a few years. It was one of the nutrients that helped when I sprained my ankle when visiting my brother in Las Vegas. More here

As you can see there is no mention of pain on the label or product description. I share more on the pain/endorphin connection below.

You can purchase this online from their website or from iherb. If you use my iherb link you’ll save 5%. This is a good option if you’re not in the USA and already use iherb for one-stop shopping of quality products.

The other DPA product I recommend: Lidtke Endorphigen

The other product I recommend is Lidtke Endorphigen which also contains 500 mg DPA and a small amount of vitamin B6 and riboflavin (vitamin B2). As you can see, this product does mention pain but not the emotional support/mood benefits on the front label.

lidke endorphigen

Here is the Lidtke Endorphigen description

Ease Minor Pain & Feel Good with Healthy Endorphin Level Maintenance

Endorphins are nature’s way to relieve common minor pain and promote a cheerful mood. Research shows that endorphins are released in response to pain and stress, bringing relief. The second wind and runner’s high during and after a vigorous run are results of endorphins. Acting as an analgesic and sedative, endorphins diminish our perception of pain…. But there is more.

Recovery centers report that endorphins promote recovery from a wide variety of unhealthy cravings.

Low endorphin symptoms and typical dosing of DPA

I use the symptoms questionnaire to help clients identify if they have low endorphin symptoms (you can see that here).

Typical dosing is 500 mg to 1000 mg DPA 3-4 x day between meals/away from protein. I do find having clients open the capsule onto their tongue to be more effective for quick pain relief – with results as quickly as 5-10 minutes.

DPA vs DLPA: they are quite different but have some overlaps

I am often asked if DPA and DLPA are the same – they are quite different but have some overlaps as outlined in this blog post on the topic: What is the difference between DPA and DLPA (amino acids) and which one do I use for weepiness, heart-ache, pain and energy?

The precautions are also not the same so I always review contraindications with all my clients and encourage you to do the same.

DPA for MS pain, weepiness, emotional pain and more

Here are a few blog posts illustrating the use of DPA in multiple sclerosis, weepiness, physical pain, emotional pain and resilience, cravings/emotional eating and even helping to wean off prescription pain medication:

  • Multiple sclerosis: low endorphin research and the amino acid DPA (d-phenylalanine) for pain, depression, comfort and trauma support “The endogenous opioid system is …well known to play a role in the development of chronic pain and negative affect [i.e. depression], both of which are common comorbidities in MS.”
  • DPA for weepiness, pain and comfort and reward eating
  • The individual amino acids glutamine, GABA, tryptophan (or 5-HTP), DPA and tyrosine are powerful for eliminating sugar cravings, often within 5 minutes
  • When using the amino acid DPA (d-phenylalanine) I have more resilience and more buffer in the caregiving work I do, and just the oops’s of life As I mentioned above, using DPA over these holidays also gave me more resilience and the endorphin boost I needed help with the emotional pain of losing my mom.
  • Wean off prescription pain medication, improve sleep and reduce emotional eating with DPA (an endorphin-boosting amino acid)

Be sure to use the search feature on the blog to find additional applications of DPA.

DPA research on pain and depression

The use of DPA is not new as you can read in this paper from 1982 – D-phenylalanine and other enkephalinase inhibitors as pharmacological agents: implications for some important therapeutic application

A number of compounds have been shown to inhibit the degradation of enkephalins. As expected, these compounds produce naloxone reversible analgesia and potentiate the analgesia produced by enkephalins and by acupuncture.

One of these, D-phenylalanine, is also anti-inflammatory.

D-phenylalanine has proven to be beneficial in many human patients with chronic, intractable pain. It is proposed the enkephalinase inhibitors may be effective in a number of human “endorphin deficiency diseases” such as depression, schizophrenia, convulsive disorders and arthritis.

Additional resources when you are new to using DPA and the other amino acids as supplements

We use the symptoms questionnaire to figure out if low endorphins or other neurotransmitter imbalances may be an issue for you.

If you suspect low levels of any of the neurotransmitters and do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the practitioner/health team you or your loved one is working with.

There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, gluten, blood sugar control, sugar cravings, anxiety and mood issues.

The book doesn’t include product names (per the publisher’s request) so this blog, The Antianxiety Food Solution Amino Acid and Pyroluria Supplements, lists the amino acids that I use with my individual clients and those in my group programs. You can find them all – including the Lidtke Endorphigen 500 mg that I mentioned above.

Also mentioned above is Doctor’s Best D-Phenylalanine which can be purchased on iherb.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA QuickStart Program (if you have low GABA symptoms too). This is a paid online/virtual group program where you get my guidance and community support.

If you are a practitioner, join us in The Balancing Neurotransmitters: the Fundamentals program. This is also a paid online/virtual program with an opportunity to interact with me and other practitioners who are also using the amino acids.

Have you had success using DPA for toothache, dental abscess or your other pain issues – what kind of pain has it helped and how much has helped you?

Has DPA also helped with emotional pain and weepiness? And cravings/emotional eating?

If you’re a practitioner do you have success using DPA with your clients/patients?

Feel free to share and ask your questions below.

Filed Under: Depression, DPA/DLPA, Emotional Eating, Endorphins, Pain Tagged With: Acupuncture, amino acids, cavity, crown, d-phenylalanine, dentist, depression, dl-phenylalanine, DLPA, Doctor’s Best D-Phenylalanine, DPA, dull ache, emotional pain, emotional well-being, endorphins, GABA Quickstart; Balancing Neurotransmitters: the Fundamentals program for practitioners, headache, Lidtke Endorphigen, muscle sprains, physical pain, tooth pain, weepiness

Non-celiac gluten sensitivity manifestations outside the gut: foggy mind, depression, anxiety, neuropathy, joint pain, headache, fatigue and IBS

July 1, 2022 By Trudy Scott 2 Comments

non-celiac gluten sensitivity

Celiac disease is “a digestive and autoimmune disorder that can damage your small intestine. People with celiac disease might experience symptoms like diarrhea, bloating, gas, anemia and growth issues. Celiac disease can be triggered by a protein called gluten. Gluten is found in grains, like wheat, barley and rye” (and oats that are contaminated with gluten). This description by the Cleveland Clinic is well-understood and recognized.

However, what is less recognized and understood, is extra-intestinal (or outside the gut) manifestations of non-celiac gluten sensitivity.  A paper published in 2018, Extra-intestinal manifestations of non-celiac gluten sensitivity: An expanding paradigm lists a number of symptoms and conditions that gluten consumption may cause and/or contribute to, even when you do not have celiac disease.

These can include: ‘foggy mind’; psychiatric diseases such as depression, anxiety and even psychosis; gluten ataxia, gluten neuropathy and gluten encephalopathy (causing memory and cognitive problems); joint and muscle pain, and leg or arm numbness; headache and fatigue;  irritable bowel syndrome (IBS); autoimmune disorders; and and fibromyalgia.

This blog post highlights excerpts from the 2018 non-celiac gluten sensitivity paper and stories from real people who have experienced relief when removing gluten from their diets. And resources if you find you need neurotransmitter support to help break the addiction and not feel deprived.

This is from the abstract of the above paper:

Non celiac gluten sensitivity (NCGS) is a syndrome characterized by a cohort of symptoms related to the ingestion of gluten-containing food in subjects who are not affected by celiac disease (CD) or wheat allergy. The possibility of systemic manifestations in this condition has been suggested by some reports.

  • In most cases they are characterized by vague symptoms such as ‘foggy mind’, headache, fatigue, joint and muscle pain, leg or arm numbness even if more specific complaints have been described.
  • NCGS has an immune-related background. Indeed there is strong evidence that a selective activation of innate immunity may be the trigger for NCGS inflammatory response. The most common autoimmune disorders associated with NCGS are Hashimoto thyroiditis, dermatitis herpetiformis, psoriasis and rheumatologic diseases.
  • A possible neurological involvement has been underlined by NCGS association with gluten ataxia, gluten neuropathy and gluten encephalopathy.
  • NCGS patients may show even psychiatric diseases such as depression, anxiety and psychosis.
  • Finally, a link with functional disorders (irritable bowel syndrome and fibromyalgia) is a topic under discussion.

We see all this clinically so it’s wonderful to see this being addressed in the research. However, the authors are saying we need more research and better studies:

the novelty of this matter has generated an expansion of literature data with the unavoidable consequence that some reports are often based on low levels of evidence. Therefore, only studies performed on large samples with the inclusion of control groups will be able to clearly establish whether the large information from the literature regarding extra-intestinal NCGS manifestations could be supported by evidence-based agreements.

Until then we use what we know works clinically: a gluten-free diet and observation of symptom resolution. We also use amino acids to balance brain chemicals so we break the addiction and don’t feel deprived (more on that below). Nutritional deficiencies caused by damage to the gut/leaky gut also need to be addressed, as well as healing the leaky gut and dysbiosis.

I shared the study abstract on Facebook asking for feedback and the response was so overwhelming that I can only share some of the feedback. I will do follow-up posts sharing more detailed information from their healing journeys.

Caroline had bloating, pain and chronic sadness, and discovered  “joie de vivre”

Caroline confirmed that she has gluten sensitivity saying she stopped eating wheat in 2011:

Within a few months, my chronic sadness disappeared and I discovered the “joie de vivre”. It also allowed me to get rid of my swelling belly (bloating). Every evening I looked like a woman 2-3 months pregnant. [this likely falls into the irritable bowel syndrome category mentioned in the paper]

The pain in my joints also ended up disappearing.

I read so much about gluten once I started to realize it had changed my life to quit eating that stuff that now I’m convinced grains shouldn’t be part of human food, and I mean all grains (botanically speaking).

I think grains should at least be taken off all the menus in all hospitals, especially the psychiatric ones.

I adore her “joie de vivre” feedback and am so happy for her! I had this same feeling of pure joy when I went gluten-free. And I get so much feedback like this from clients who had no idea life could be so much better.

I also agree with her sentiment about gluten and grains being an issue too, especially in psychiatric settings.

Daphne was emotionally dysregulated with negative feelings and a pressure headache

Daphne shared what she calls an odd effect that she gets soon after eating bread: roiling emotions:

I get emotionally dysregulated. Negative feelings surface in various degrees, for me primarily anger and the reviewing of the incidents that caused it (aka ruminating thoughts?); less often sadness, disappointment, and overwhelm (that usually surfaces on its own anyway).

I also get what I call ‘bread head.’ I get a pressure headache from between my eyebrows, up the center of my head to my crown.

An additional effect: ‘the hangover’. Overnight the pressure headache subsides and the next day my whole head feels heavy and I am slower physically and mentally, and my hands in particular are achy

Also, I have had chicken bumps on my skin my whole life, until I stopped eating bread. I still have some, maybe from rice, potato and corn reactions. Starch is not my friend.

As I mentioned above, many folks are surprised at the emotional changes they see when eating gluten. Daphne called it an odd effect but her response is a very typical extra-intestinal (outside the gut) psychiatric response. And yes starches and grains are an issue for many folks.

Other feedback: fibromyalgia pain, brain fog, depression, cystic acne, anxiety, body aches, fatigue, PCOS and hypothyroidism

Here is some feedback from a few other women. As you can see the symptoms can vary per person:

  • “Removal of gluten and all grains has improved my fibromyalgia pain symptoms … The difference in pain was so dramatic that it was worth it.”
  • “It makes such a difference with my brain fog and depression! And cystic acne. If I have gluten, I have cystic acne for about 2 weeks.”
  • “My joint pain, anxiety, and depression are much improved when I avoid gluten (and corn.)”
  • “Yes! Within 15 min of ingesting gluten containing food I get all over body aches, fatigue and brain fog. It’s very unpleasant. I cut gluten out of my diet simply because I can’t function properly while eating it. I also have had episodes of reactive hypoglycemia from it too.”
  • “Removing gluten has cured my hypothyroidism. Also has improved my PCOS, anxiety and depression.”

Stay tuned for a follow-up blog with more from their healing journeys and additional insights from me.

Using the amino acids to help break the gluten addiction and feel less deprived

Sometimes it’s difficult to figure out why you crave or are addicted to gluten. It can be challenging to determine which part of your brain chemistry it’s affecting, and you may not associate cravings with mood issues.

Your drug-of-choice is something you self-medicate with and it is something that makes you feel good or “normal.” It could be starchy gluten-containing foods like bread or pasta or cookies. It could also be candy, chocolate, ice-cream, coffee, sodas, wine/beer, cigarettes, marijuana, a prescription medication like Prozac, street drugs, or even shopping or exercise.

Cravings for these substances (or behaviors) typically indicate a brain chemistry imbalance, so it’s very helpful to identify how the substances you crave affect you. This will help you determine which amino acids you might supplement to address the imbalance.

Use your “drug-of-choice” from your gluten or grain list (perhaps you love bread or chocolate chip muffins) and the chart below to help you determine what brain chemistry imbalance may be affecting you and which amino acid you may benefit from.

How you feel before How you feel after Brain chemistry imbalance Amino acid to supplement
Anxious or stressed Calm or relaxed Low GABA GABA
Depressed or anxious Happy or content Low serotonin Tryptophan or 5-HTP
Tired or unfocused Energetic, alert, or focused Low catecholamines Tyrosine
Wanting a reward or sad Rewarded or comforted Low endorphins DPA (d-phenylalanine)
Irritable and shaky Grounded or stable Low blood sugar Glutamine

Once you address that brain chemical imbalance, it’s easy to quit and you won’t feel deprived.

You can read more about why you crave on this blog post

Resources if you are new to using the amino acids as supplements

If you are new to using any of the amino acids as supplements, here is the Amino Acids Mood Questionnaire from The Antianxiety Food Solution (you can see all the symptoms of neurotransmitter imbalances).

If you suspect low levels of any of the neurotransmitters and do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the practitioner/health team you or your loved one is working with.

There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, gluten, blood sugar control, sugar cravings, self-medicating with alcohol and more. There is also an entire chapter on gluten and grains if this is new to you.

The book doesn’t include product names (per the publisher’s request) so this blog, The Antianxiety Food Solution Amino Acid and Pyroluria Supplements, lists the amino acids that I use with my individual clients and those in my group programs.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA Quickstart Program (if you have low GABA symptoms). This is a paid online/virtual group program where you get my guidance and community support. There are many moms in the program who are having much success with their kids.

If you are a practitioner, join us in The Balancing Neurotransmitters: the Fundamentals program. This is also a paid online/virtual program with an opportunity to interact with me and other practitioners who are also using the amino acids.

With much appreciation for these women for sharing their stories. I’d love to get some of these published as case studies to further add to the evidence.

Do you have (or suspect you may have) non celiac gluten sensitivity (NCGS)?

And has gluten removal resolved any of the above issues? And have you seen an improvement in gut issues too?

Have you observed other improvements since eating gluten and/or grain-free?

Did you find the amino acids helped you break your addiction and feel less deprived?

Or are you stuck and still eating gluten and have no idea where to start on quitting? If this is you, would a webinar series help?

If you have questions please share them here too.

Filed Under: Anxiety, Endorphins, GABA, Gluten, Pain, serotonin Tagged With: "joie de vivre", addiction, amino acids, anxiety, Autoimmunity, bloating, body aches, brain fog, celiac, cystic acne, depression, deprived, emotionally dysregulated, extra-intestinal, fatigue, Fibromyalgia, foggy mind, GABA, GABA Quickstart program, gluten, gluten encephalopathy, headache, hypothyroidism, IBS, joint pain, NCGS, negative feelings, neuropathy, Non-celiac gluten sensitivity, outside the gut, PCOS, psychosis, sadness, wheat

Anxiety case study: a very very slow SSRI taper with tryptophan and other nutritional support

August 28, 2020 By Trudy Scott 14 Comments

anxiety case study

Today I’m sharing an update from someone in my community who is tapering from an SSRI (Cipralex/lexapro) in the best way possible – very methodically and doing a very very slow taper, using compounded medication and nutritional support. It is a team approach with a supportive doctor monitoring for serotonin syndrome, her pharmacist compounding her medication and input from me.

She has an excellent diet that contains enough healthy protein and fats, plenty of vegetables, and no sugar or caffeine. She has the basic nutrients covered and is on the pyroluria protocol (these nutrients help make serotonin). She is using the amino acid tryptophan for serotonin support as she tapers. And she is out walking in nature and practicing mindfulness.

All of this sets her up for success and being able to avoid antidepressant discontinuation syndrome.

Here is her story:

I began tapering off 10 mg of Cipralex in November 2017. I have my little “Support Team” that includes a compounding pharmacist and my GP. Feeling very fortunate that I have these people as my taper has not exactly gone as planned (although far better than my last two attempts)

Originally, the plan was to go down by 10% of the dose and stay at that dose for 4 weeks. That didn’t work for me. I was fine when I dropped from 10mg to 9, but after my next 10% drop I experienced that familiar withdrawal hell. I got a little scared, but stuck with it, and decided to stay at that dose for a bit longer. While I leveled out, I did a lot of reading about how SSRIs work. I learned about the 1/2 life of Cipralex (all SSRIs have a different 1/2 life) and what was actually happening physiologically as my body adjusts to the lower dose. It’s a recovery process.

With that new knowledge, I decided to try another approach. I knew I couldn’t handle a drop of 10%. So, I started to taper at a rate of 0.1mg once a week (far less than 10%!). By day three at the new dose, I could feel the withdrawal, but it was far less severe. Small drops=small “withdrawal wave”. I discovered that I am able to manage a 2% drop of the current dose and I have been able to drop that % each week. So, I’m still reducing by 8% a month, which means I am close to the original plan of dropping by 10% a month. At this time I am at 6.24mg.

Yes, it is a very slow process and I have a long way to go, but it’s working. I have read that some people have to reduce by 1% of their current dose and remain at that dose for 4 weeks to allow their body the time to heal and adjust to life on the lower dose. Having the liquid compound has made such a difference! You sure would have difficulty accurately shaving off a pill by 2%!! If anyone is trying to come off of this drug, do your best to find a compounding pharmacist!

I find that I must stick to a very healthy diet. I eat a lot of fresh, raw and cooked vegetables. I mean a LOT of vegetables. I eat good sources of protein and walk for at least 45 min almost every day. I steer clear of sugar and caffeine. Both make my withdrawal much worse.

Every day I take omega 3, vitamin C, vitamin D, vitamin B complex. I take the supplements for pyroluria, vitamin B6, evening primrose oil and zinc. I take magnesium at night. I took Trudy’s amino acids course online and did all of the amino acid trials. I discovered all I really need is tryptophan. It has made a huge difference for me. Yes, I take Lidke tryptophan. For us Canadians, it can be ordered online.

I practice mindfulness. I’ve read a lot about the anxious brain (the reason I took Cipralex in the first place) so I understand what is happening now, what is real and what is just noise in my head.

Antidepressant discontinuation syndrome

This is the best way to taper SSRI medications in order to avoid withdrawal effects, also known as discontinuation syndrome which can be very severe for some folks.

Accordingly to this paper, Antidepressant discontinuation syndrome occurs in about 20% of patients who reduce the dose or abruptly stop an antidepressant that they have been taking for one month. This paper states that “symptoms are usually mild….occur within two to four days after drug cessation and usually last one to two weeks.”

It also states that occasionally symptoms “may persist up to one year…and if the same or a similar drug is started, the symptoms will resolve within one to three days.”

I typically hear from individuals who fall into the category of severe symptoms that are persisting past 2 weeks. It’s not uncommon to see symptoms continue for a year and often longer in some cases.

Also from the above paper, is the mnemonic FINISH which summarizes these symptoms:

  • Flu-like symptoms (lethargy, fatigue, headache, achiness, sweating)
  • Insomnia (with vivid dreams or nightmares)
  • Nausea (sometimes vomiting)
  • Imbalance (dizziness, vertigo, light-headedness)
  • Sensory disturbances (“burning,” “tingling,” “electric-like” or “shock-like” sensations) and
  • Hyperarousal (anxiety, irritability, agitation, aggression, mania, jerkiness).”

How you will feel if your serotonin is low and how to learn more

With low serotonin you will have the worry-in-your-head and ruminating type of anxiety, panic attacks and phobias, lack of confidence, depression, negativity, imposter syndrome, PMS, irritability, anger issues, insomnia and afternoon/evening cravings.

If you suspect low serotonin symptoms and are new to using the amino acids and do not have my book I highly recommend getting it and reading it before jumping in to taking supplements and navigating this with your prescribing physician: The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings. You may need to lend him/her a copy of my book too.

There is a complete chapter on the amino acids and one for pyroluria, plus information on real whole food, sugar and blood sugar, gluten, digestion and much more.  If you’re not a reader there is now also an audible version.

Here is the Amino Acids Mood Questionnaire from The Antianxiety Food Solution and additional information on Anxiety and targeted individual amino acid supplements: a summary

Please also read and follow these Amino Acid Precautions.

This lists The Antianxiety Food Solution Amino Acid and Pyroluria Supplements that I use with my individual clients and those in my group programs – you will find the Lidtke Tryptophan here. You can also read more about why I prefer the Lidtke tryptophan on this blog.

I would like to end off by saying how much I appreciate this woman and others sharing their stories like this so we can all learn!

Please also share your taper story and what you did to make it easier.  If you had challenges share those too. Let us know if you can relate to any of the above FINISH symptoms and how long they lasted.

Feel free to post your questions here too.

Filed Under: Anxiety, Tryptophan Tagged With: achiness, aggression, agitation, antidepressant, anxiety, B6, burning, cravings, diet, Dizziness, fatigue, flu-like symptoms, headache, insomnia, irritability, jerkiness, lethargy, light-headedness, mania, nausea, Nightmares, nutritional support, panic, serotonin, shock-like sensations, SSRI, SSRI taper, sweating, tingling, tryptophan, vertigo, vivid dreams, vomiting, worry, zinc

Vitamin C, autoimmunity, food sensitivities & visual processing: Chronic Headache & Migraine Summit

July 9, 2017 By Trudy Scott 5 Comments

Guest post by Erin Knight, FDN-P

Did you know that nearly 60% of migraineurs report suffering from anxiety as well? I didn’t. That was one of many surprising things I discovered interviewing functional medicine experts and clinicians with decades of experience helping people overcome their headaches and migraines at the root cause for the Chronic Headache and Migraine Summit.

As much as the high correlation between migraines and anxiety surprised me, I could quickly see some reasons for the connection. People with frequent headaches report that managing life around headaches and missing out on things places an incredible strain on relationships and career that is nearly as bad as the physical pain. In other words, the mental agony of being sidelined by severe headaches is worse than the pain itself and contributes to the stress we carry around each day. But I don’t have to tell you that.

Is this meal going to cause a headache today? Am I going to be able to make it to my daughter’s choir concert? Is my boss going to pass me up for that project because I’ve been out with migraines so many days this year? If you are like me, these questions are always top of mind – creating a vicious circle between worrying – headaches – and more stress.

While it may seem quite obvious that there is this worrying and fear that migraineurs carry around with them each day, you may be surprised to learn from the experts speaking on the summit that there are many underlying root causes that can lead to both anxiety and headaches at a biological level. Some of these include:

  • Poor absorption of nutrients such as magnesium
  • Leaky gut and inflammation in the digestive tract that impacts the production of neurotransmitters like serotonin and hormones like estrogen
  • Emotional trauma in childhood (which is linked to a staggering increase in chronic conditions such migraines, autoimmune diseases, obesity and chronic fatigue

The good news is that there are real solutions to improve your health at a foundational level that can drastically improve or even resolve both headaches/migraines and anxiety at the root cause.

The experts in the Chronic Headache and Migraine Summit talk both about what has helped their clients recover their health as well as natural, simple ways to reduce the pain and intensity of headaches quickly and at home so you can go on with your life.

If you know you experience headaches due to weather changes, sinus stuffiness, neck tension, classic migraine or monthly hormonal changes – there are different relief techniques to employ for each. For example, Jay Davidson  highlights 3 tricks for clearing pressure out of your head when you feel a thunderstorm headache coming on – and they work in minutes! My favorite is to dab frankincense essential oil with your fingertips along the hairline in your neck. I can feel drainage start immediately with this simple technique!

If you think you’ve tried it all and been through the gamut of herbal and homeopathic remedies – I promise you will learn something that surprises you and makes a difference in your journey.

5 things I learned about hosting the Chronic Headache and Migraine Summit that might surprise you too:

  • There are many superstar supplements that can help people with different types of migraines beyond the typical riboflavin and magnesium citrate – for example, Vitamin C, different forms of magnesium, 5-HTP or tryptophan, and glutathione.
  • Migraines are being reclassified as an autoimmune disease. One autoimmune disease that frequently leads to migraines (and anxiety and miscarriages) is the clotting disease called Antiphospholipid Syndrome (featured on day 7 in Trudy Scott’s interview)
  • Food sensitivities may be more important than avoiding trigger foods
  • There is a visual processing disorder that affects 15% of the population and is simple to correct.
  • Toxicity from air and water pollution causes different types of chronic headaches and can be easily identified and reversed.

We are so thrilled to be able to offer this first-of-its-kind resource for people who want to stop managing their headaches, stop watching life pass them by from the sidelines and find natural relief options that really work.

Feel free to share something that surprises YOU from the above in the comments below.

Filed Under: Events, Migraine Tagged With: 5-HTP, antiphospholipid syndrome, anxiety, Autoimmunity, Erin Knight, food sensitivities, headache, migraine, tryptophan, visual processing, vitamin C

Migraines, anxiety, depression and gluten: on the Chronic Headache & Migraine Summit

June 26, 2017 By Trudy Scott 5 Comments

The goal of a 2015 Russian study titled Gluten Migraine, was to study the prevalence of migraine among patients with celiac disease and to assess the efficacy of a gluten-free diet in its treatment. There were 200 celiac disease (CD) patients and the

CD group had migraine syndrome four times more often than the control group. The attacks were more frequent in CD patients who were older than 50 years old.

The migraines disappeared in 25% of patients with migraines who were on the gluten free diet and the reduction in the intensity and/or frequency of attacks was observed in 38% of patients.

This is the study conclusion:

We revealed the clear association between migraine syndrome and CD and the high efficacy of gluten FREE diet in the treatment of migraine symptoms.”

I would suspect similar results if you have gluten sensitivity. And here is some gluten-migraine feedback from 4 different women in my community:

  • HUGE decrease in my migraines now that I eat more cleanly. I used to start to get headaches immediately upon eating gluten-y meals
  • I had them frequently from teenage years right up until my Celiac diagnosis in my thirties. Once gluten was gone so were the migraines
  • Stopping gluten stopped my migraines
  • My migraines always came from gluten and dairy

Of course there is also an anxiety-gluten and the depression-gluten connection so getting the gluten out of your diet will help with both anxiety and depression most of the time too.

I talked about all this on The Chronic Headache & Migraine Summit.

The other topic I covered is the autoimmune condition called Antiphospholipid Syndrome (APS) which is one of many possible contributing factors for both migraines and anxiety. Of course, with any autoimmune condition gluten removal is key.

I also cover low serotonin as one possible cause of migraines (and anxiety) and the use of tryptophan (instead of SSRIs). An amino acid like tryptophan or GABA also helps you break the gluten addiction so you don’t have to rely only on willpower!

Have you got questions or comments? Please post in the comment box below.

Filed Under: Events, Migraine Tagged With: amino acids, anxiety, depression, gluten, headache, migraine, serotonin, tryptophan, willpower

Migraines, Anxiety and Antiphospholipid Syndrome: on the Chronic Headache & Migraine Summit

June 12, 2017 By Trudy Scott 39 Comments

The autoimmune condition called Antiphospholipid Syndrome (APS) is one of many possible contributing factors for both migraines and anxiety. I came across this condition when researching the links between migraine and anxiety in preparation for my interview with Erin Knight, one of the hosts of The Chronic Headache & Migraine Summit. This is one of the reasons I love presenting because I get to learn so much too!

Antiphospholipid syndrome occurs when your immune system attacks some of the normal proteins in your blood. It can cause blood clots in your arteries or veins. And it can cause pregnancy complications, such as miscarriage and stillbirth. (Source: Mayo Clinic)

I share some highlights from a 2015 paper: Antiphospholipid antibodies as biomarkers in psychiatry

  • Antiphospholipid syndrome (APS) has been implicated in a range of neuropsychiatric presentations
  • The link between depression, stroke, and cardiovascular disease could be explained in at least some patients by the presence of aPL antibodies
  • Approximately one in five (20%) strokes in individuals under the age of 45 years are associated with APS
  • Migraine is one of the most commonly observed symptoms in patients with APS
  • aPL antibodies are often found to show low or moderately positive levels which makes this syndrome a diagnostic dilemma in psychiatry. The St. Thomas ‘alternative criteria’ for APS may be a useful clinical tool for psychiatrists. These criteria include cognitive impairment, affective disorders [like depression and anxiety], headaches [or migraines], and livedo reticularis, with improvement after aspirin treatment

In case you are not familiar with livedo reticularis, it is a mottled purplish discoloration of the skin. Having this skin condition does not mean you have APS because livedo reticularis can be a normal condition that is simply more obvious when you are exposed to the cold. It can also be an indicator of impaired circulation.

Phospholipids are a class of lipids that are a major component of all cell membranes and also facilitate neurotransmitters communication so this condition affects serotonin, dopamine, glutamate and GABA levels.

Working with my client’s doctor, I would recommend an autoimmune dietary approach and trials of the respective amino acids to support low serotonin, low GABA (anxiety is common with migraine sufferers) and low dopamine.

We also discuss how effective gluten removal can be for my clients with anxiety and migraines and find it to be a common underlying factor (whether it’s celiac disease or gluten sensitivity). Since gluten is always an important factor for autoimmunity it should always be explored if APS has been diagnosed or is suspected.

We also cover low serotonin as one possible cause of migraines and the how to do a trial of tryptophan (instead of SSRIs). Using tryptophan also addresses the low serotonin that often occurs with APS and is one possible contributing cause of the anxiety, depression, insomnia and migraines.

Hosts of The Chronic Headache & Migraine Summit, Erin Knight, Corey Schuler and Marta Taylor, are familiar with headache pain and migraines; they’ve all experienced severe headache problems. They found functional medicine solutions, which they now share in their health practices each day.

Filed Under: Anxiety and panic, Depression, Events, Migraine Tagged With: antiphospholipid syndrome, anxiety, gluten, headache, livedo reticularis, migraine, serotonin, stroke

Primary Sidebar

NEW! GABA QuickStart Homestudy (with special intro pricing)

gaba quickstart homestudy

Free Report

9 Great Questions Women Ask about Food, Mood and their Health

You'll also receive a complimentary subscription to my ezine "Food, Mood and Gal Stuff"


 

Connect with me

Popular Posts

  • Amino Acids Mood Questionnaire from The Antianxiety Food Solution
  • The Antianxiety Food Solution Amino Acid and Pyroluria Supplements
  • Pyroluria Questionnaire from The Antianxiety Food Solution
  • Collagen and gelatin lower serotonin: does this increase your anxiety and depression?
  • Tryptophan for the worry-in-your-head and ruminating type of anxiety
  • GABA for the physical-tension and stiff-and-tense-muscles type of anxiety
  • The Antianxiety Food Solution by Trudy Scott
  • Seriphos Original Formula is back: the best product for anxiety and insomnia caused by high cortisol
  • Am I an anxious introvert because of low zinc and vitamin B6? My response to Huffington Post blog
  • Vagus nerve rehab with GABA, breathing, humming, gargling and key nutrients

Recent Posts

  • What do I use instead of Seriphos to help lower high cortisol that is affecting my sleep and making me anxious at night?
  • BeSerene™ GABA/theanine cream eases severe muscle tension in her neck/shoulders, prevents her bad headaches and quells her anxiety
  • How the correct approach, dose and sublingual use of GABA can be calming and not cause a flushed and itchy face and neck
  • The amino acid glutamine improves low mood by addressing gut health, and it has calming effects too
  • Flight anxiety with heightened breath, physical tension and also fearing the worst (the role of low GABA and low serotonin)

Categories

  • 5-HTP
  • AB575
  • Addiction
  • ADHD
  • Adrenals
  • Alcohol
  • Allergies
  • Alzheimer's disease
  • Amino Acids
  • Anger
  • Antianxiety
  • Antianxiety Food Solution
  • Antidepressants
  • Anxiety
  • Anxiety and panic
  • Autism
  • Autoimmunity
  • benzodiazapines
  • Bipolar disorder
  • Books
  • Caffeine
  • Cancer
  • Candida
  • Children/Teens
  • Collagen
  • Cooking equipment
  • Coronavirus/COVID-19
  • Cravings
  • Depression
  • Detoxification
  • Diabetes
  • Diet
  • DPA/DLPA
  • Drugs
  • EFT/Tapping
  • EMF
  • EMFs
  • Emotional Eating
  • Endorphins
  • Environment
  • Essential oils
  • Events
  • Exercise
  • Fear
  • Fear of public speaking
  • Fertility and Pregnancy
  • Fish
  • Food
  • Food and mood
  • Functional neurology
  • GABA
  • Gene polymorphisms
  • General Health
  • Giving
  • Giving back
  • Glutamine
  • Gluten
  • GMOs
  • Gratitude
  • Gut health
  • Heart health/hypertension
  • Histamine
  • Hormone
  • Hyperparathyroidism
  • Hypoglycemia
  • Immune system
  • Inflammation
  • Insomnia
  • Inspiration
  • Introversion
  • Joy and happiness
  • Ketogenic diet
  • Lithium orotate
  • Looking awesome
  • Lyme disease and co-infections
  • MCAS/histamine
  • Medication
  • Men's health
  • Mental health
  • Mercury
  • Migraine
  • Mold
  • Movie
  • MTHFR
  • Multiple sclerosis
  • Music
  • NANP
  • Nature
  • Nutritional Psychiatry
  • OCD
  • Osteoporosis
  • Oxalates
  • Oxytocin
  • Pain
  • Paleo
  • Parasites
  • Parkinson’s disease
  • PCOS
  • People
  • PMS
  • Postpartum
  • PTSD/Trauma
  • Pyroluria
  • Questionnaires
  • Real whole food
  • Recipes
  • Research
  • Schizophrenia
  • serotonin
  • SIBO
  • Sleep
  • Special diets
  • Sports nutrition
  • Stress
  • Sugar addiction
  • Sugar and mood
  • Supplements
  • Teens
  • Testimonials
  • Testing
  • The Anxiety Summit
  • The Anxiety Summit 2
  • The Anxiety Summit 3
  • The Anxiety Summit 4
  • The Anxiety Summit 5
  • The Anxiety Summit 6
  • Thyroid
  • Thyroid health
  • Toxins
  • Tryptophan
  • Tyrosine
  • Uncategorized
  • Vegan/vegetarian
  • Women's health
  • Yoga

Archives

  • October 2025
  • September 2025
  • August 2025
  • July 2025
  • June 2025
  • May 2025
  • April 2025
  • March 2025
  • February 2025
  • January 2025
  • November 2024
  • October 2024
  • September 2024
  • August 2024
  • July 2024
  • June 2024
  • May 2024
  • April 2024
  • March 2024
  • February 2024
  • January 2024
  • December 2023
  • November 2023
  • October 2023
  • September 2023
  • August 2023
  • July 2023
  • June 2023
  • May 2023
  • April 2023
  • March 2023
  • February 2023
  • January 2023
  • December 2022
  • November 2022
  • October 2022
  • September 2022
  • August 2022
  • July 2022
  • June 2022
  • May 2022
  • April 2022
  • March 2022
  • February 2022
  • January 2022
  • December 2021
  • November 2021
  • October 2021
  • September 2021
  • August 2021
  • July 2021
  • June 2021
  • May 2021
  • April 2021
  • March 2021
  • February 2021
  • January 2021
  • December 2020
  • November 2020
  • October 2020
  • September 2020
  • August 2020
  • July 2020
  • June 2020
  • May 2020
  • April 2020
  • March 2020
  • February 2020
  • January 2020
  • December 2019
  • November 2019
  • October 2019
  • September 2019
  • August 2019
  • July 2019
  • June 2019
  • May 2019
  • April 2019
  • March 2019
  • February 2019
  • January 2019
  • December 2018
  • November 2018
  • October 2018
  • September 2018
  • August 2018
  • July 2018
  • June 2018
  • May 2018
  • April 2018
  • March 2018
  • February 2018
  • January 2018
  • December 2017
  • November 2017
  • October 2017
  • September 2017
  • August 2017
  • July 2017
  • June 2017
  • May 2017
  • April 2017
  • March 2017
  • February 2017
  • January 2017
  • December 2016
  • November 2016
  • October 2016
  • September 2016
  • August 2016
  • July 2016
  • June 2016
  • May 2016
  • April 2016
  • March 2016
  • February 2016
  • January 2016
  • December 2015
  • November 2015
  • October 2015
  • September 2015
  • August 2015
  • July 2015
  • June 2015
  • May 2015
  • April 2015
  • March 2015
  • February 2015
  • January 2015
  • December 2014
  • November 2014
  • October 2014
  • September 2014
  • August 2014
  • July 2014
  • June 2014
  • May 2014
  • April 2014
  • March 2014
  • February 2014
  • January 2014
  • December 2013
  • November 2013
  • October 2013
  • September 2013
  • August 2013
  • July 2013
  • June 2013
  • May 2013
  • April 2013
  • March 2013
  • February 2013
  • January 2013
  • December 2012
  • November 2012
  • October 2012
  • August 2012
  • July 2012
  • June 2012
  • May 2012
  • April 2012
  • March 2012
  • February 2012
  • January 2012
  • December 2011
  • November 2011
  • October 2011
  • September 2011
  • August 2011
  • July 2011
  • June 2011
  • May 2011
  • April 2011
  • March 2011
  • February 2011
  • January 2011
  • December 2010
  • October 2010
  • September 2010
  • July 2010
  • May 2010
  • April 2010
  • March 2010
  • February 2010
  • January 2010
  • November 2009

Share the knowledge!

The above statements have not been evaluated by the Food and Drug Administration. Products listed in this website are not intended to diagnose, treat, cure or prevent any disease.

The information provided on this site is for informational and educational purposes only and is not intended as a substitute for advice from your physician or other health care professional. You should consult with a healthcare professional before starting or modifying any diet, exercise, or supplementation program, before taking or stopping any medication, or if you have or suspect you may have a health problem.

 

Copyright © 2026 Trudy Scott. All Rights Reserved. | Privacy | Terms and Conditions | Refund Policy | Medical Disclaimer

Free Report

9 Great Questions Women Ask about Food, Mood and their Health

You’ll also receive a complimentary subscription to my ezine “Food, Mood and Gal Stuff”