• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar

everywomanover29

Food, Mood and Women's Health – Be your healthiest, look and feel great!

  • Blog
  • About
  • Services
  • Store
  • Resources
  • Testimonials
  • Media
  • The Book
  • Contact

MAPS

MDMA-Assisted Psychotherapy for Treating Chronic PTSD: Why I feel we can do better and the role of nutrition and amino acids like GABA

November 2, 2018 By Trudy Scott 5 Comments

You may be familiar with MDMA (3,4-methylenedioxymethamphetamine), also known as “ecstasy”, because of its reputation as a party drug. And you have likely seen some of the media reports on the new research and growing support for MDMA-Assisted psychotherapy for treating chronic PTSD (post-traumatic stress disorder). Due to adverse effects I’d like to share my concerns about this research and treatment and why I feel we can do better – by addressing nutrition and using amino acids like GABA and others.

In a recent press release, Colorado Study Shows Lasting Benefits of MDMA-Assisted Psychotherapy for Treating Chronic PTSD, the non-profit organization, Multidisciplinary Association for Psychedelic Studies (MAPS) reports these study results:

28 participants found that one month after their second day-long experimental session, 42.9% in the active-dose (100 mg and 125 mg) MDMA groups did not qualify for a diagnosis of PTSD, compared to 33.3% in the low-dose MDMA (40 mg active placebo) control group.

The results were even more notable 12 months after the third active-dose experimental session, which found that one year following treatment with MDMA-assisted psychotherapy, 76% of participants no longer had PTSD.

It is the largest U.S. FDA-regulated double-blind, placebo-controlled clinical trial of MDMA-assisted psychotherapy for the treatment of chronic PTSD and the results are impressive: 76% of the study participants no longer had PTSD after a year and 3 treatment sessions. I’m really happy for the participants BUT I believe we can do better because there are adverse reactions to this treatment and there are other safer approaches for recovery.

This comment about an acceptable risk profile and adverse reactions concerns me (and I suspect it concerns you too):

The study replicated previous research showing an acceptable risk profile for MDMA, with the most frequently reported adverse reactions during experimental sessions being anxiety, jaw clenching, headache, muscle tension, dizziness, fatigue, and low mood.

Adverse reactions one week following treatment included insomnia, low mood, irritability, and ruminations. Temporary elevations in pulse, blood pressure, and temperature were also recorded during MDMA sessions, and did not require medical intervention.

A common theme we see in the research on psychedelics is how effective it is for PTSD that doesn’t respond to therapy or medications. This paper states:

There is an immense need for innovative treatment options that improve outcomes, especially for PTSD refractory to psychotherapy and/or pharmacotherapies

I agree there is an immense need for successful treatment approaches, but jumping to MDMA from psychotherapy and/or psychiatric medications is skipping out the entire nutritional and biochemical step which is SO powerful and doesn’t have the above adverse effects. I’m concerned too many who have not seen benefits from therapy or medications are seeing MDMA as THE solution and are going to be harmed even further.

This paper, The Potential Dangers of Using MDMA for Psychotherapy, the author is concerned about the fact that “acute MDMA can stimulate the release of difficult feelings and memories, which may be distressing” and also the negative moods that occur after MDMA treatment:

This period of negative cognitions may be counter-productive, especially in psychiatrically vulnerable clients, for instance those with predispositions to anxiety, depression, or psychosis. For example, it could increase the likelihood of suicide in those individuals with strong post-recovery feelings of depression.

Because of this, I wholeheartedly agree with the author’s position:

it will always be far safer to undertake psychotherapy without using co-drugs. In selected cases MDMA might provide an initial boost, but it also has far too many potentially damaging effects for safe general usage.

In addition to psychotherapy, there are also so many nutritional and biochemical factors we can consider when it comes to PTSD. These don’t have any of the above damaging effects seen with MDMA. Here are a few to consider:

  • In this blog post, PTSD from 3 tours in Afghanistan: Can GABA help with the anxiety? how low GABA can lead to physical anxiety, muscle tension and the need to self-medicate with alcohol or sugary foods in order to calm down and relax. We also have research supporting the use of GABA for helping with unwanted obtrusive thoughts which are common with PTSD. When low GABA is suspected we do an amino acid trial with GABA, one of the calming amino acids.
  • A 2016 reports that blueberries boost serotonin and may help with PTSD and anxiety https://www.everywomanover29.com/blog/blueberries-serotonin-ptsd-anxiety/. This was an animal study where the traumatized rats were fed a blueberry-enriched diet. The study authors report an increase in serotonin levels, suggesting that “non-pharmacological approaches might modulate neurotransmitters in PTSD.”
  • A recent meta-analysis, Association between posttraumatic stress disorder and lack of exercise, poor diet, obesity, and co-occuring smoking, confirms the diet and lifestyle connection to being more impacted by trauma when health is not optimal.

I feel it is these above approaches and others like this that we need to be using to address PTSD, rather than subjecting individuals who are already suffering to treatments that have adverse reactions AND are not addressing underlying nutritional deficiencies of low GABA, low serotonin, out of balance endocannabinoid system and overall health, to name a few of many possible underlying biochemical factors.

If this treatment approach is approved, I would hope that all the adverse effects and dangers are clearly explained and I’d also like there to be informed consent before it is used – so individuals know exactly what they are getting into. Hopefully, by the time it is approved, nutritional psychiatry will be more accepted.

I’d love to hear your thoughts on this research and treatment approach. Is it something you have considered or would possibly consider in the future – you personally or with patients?

Or do you have similar concerns that I have?

Have you already tried MDMA recreationally (possibly for therapeutic reasons) and what were your experiences like?

Filed Under: PTSD Tagged With: anxiety, biochemical, blueberries, depression, GABA, insomnia, irritability, low mood, MAPS, MDMA, nutrition, nutritional, PTSD, ruminations

Primary Sidebar

FREE REPORT

9 Great Questions Women Ask about Food, Mood and their Health

You’ll also receive a complimentary subscription to my ezine “Food, Mood and Gal Stuff”

Success! Check your inbox for our email with a download link.

Connect with me

Recent Posts

  • GABA Calm is in short supply – what other GABA products are there for easing anxiety?
  • ADHD: 5-HTP melts have been a miracle for one of my adopted kids
  • GABA eases anxiety and is protective against metabolic and reproductive disturbances in polycystic ovarian syndrome (PCOS)?
  • GABA helps a stressed young boy with episodes of “choking” or tightening in his throat
  • Christmas tree phenols as a trigger for anger, meltdowns, anxiety, hyperactivity, insomnia, aggression, self-injury and autistic symptoms?

Categories

  • AB575
  • Addiction
  • ADHD
  • Adrenals
  • Alzheimer's disease
  • Amino Acids
  • Antianxiety
  • Antianxiety Food Solution
  • Antidepressants
  • Anxiety
  • Anxiety and panic
  • Anxiety Summit 5
  • Anxiety Summit 6
  • Autism
  • Autoimmunity
  • benzodiazapines
  • Bipolar disorder
  • Books
  • Caffeine
  • Cancer
  • Candida
  • Children
  • Cooking equipment
  • Coronavirus/COVID-19
  • Cravings
  • Depression
  • Detoxification
  • Diabetes
  • Diet
  • Drugs
  • EFT/Tapping
  • EMF
  • EMFs
  • Emotional Eating
  • Environment
  • Essential oils
  • Events
  • Exercise
  • Fear of public speaking
  • Fertility and Pregnancy
  • Fish
  • Food
  • Food and mood
  • Functional neurology
  • GABA
  • Gene polymorphisms
  • General Health
  • Giving
  • Giving back
  • Glutamine
  • Gluten
  • GMOs
  • Gratitude
  • Gut health
  • Heart health
  • Histamine
  • Hormone
  • Immune system
  • Inflammation
  • Insomnia
  • Inspiration
  • Introversion
  • Joy and happiness
  • Ketogenic diet
  • Looking awesome
  • Lyme disease and co-infections
  • Medication
  • Mental health
  • Mercury
  • Migraine
  • Mold
  • Movie
  • MTHFR
  • Music
  • NANP
  • Nature
  • Nutritional Psychiatry
  • OCD
  • Oxalates
  • Oxytocin
  • Pain
  • Paleo
  • Parasites
  • People
  • Postpartum
  • PTSD
  • Pyroluria
  • Questionnaires
  • Real whole food
  • Recipes
  • Research
  • serotonin
  • SIBO
  • Sleep
  • Special diets
  • Stress
  • Sugar addiction
  • Sugar and mood
  • Supplements
  • Teens
  • Testimonials
  • Testing
  • The Anxiety Summit
  • The Anxiety Summit 2
  • The Anxiety Summit 3
  • The Anxiety Summit 4
  • Thyroid
  • Thyroid health
  • Toxins
  • Tryptophan
  • Uncategorized
  • Vegan/vegetarian
  • Women's health
  • Yoga

Archives

  • January 2021
  • December 2020
  • November 2020
  • October 2020
  • September 2020
  • August 2020
  • July 2020
  • June 2020
  • May 2020
  • April 2020
  • March 2020
  • February 2020
  • January 2020
  • December 2019
  • November 2019
  • October 2019
  • September 2019
  • August 2019
  • July 2019
  • June 2019
  • May 2019
  • April 2019
  • March 2019
  • February 2019
  • January 2019
  • December 2018
  • November 2018
  • October 2018
  • September 2018
  • August 2018
  • July 2018
  • June 2018
  • May 2018
  • April 2018
  • March 2018
  • February 2018
  • January 2018
  • December 2017
  • November 2017
  • October 2017
  • September 2017
  • August 2017
  • July 2017
  • June 2017
  • May 2017
  • April 2017
  • March 2017
  • February 2017
  • January 2017
  • December 2016
  • November 2016
  • October 2016
  • September 2016
  • August 2016
  • July 2016
  • June 2016
  • May 2016
  • April 2016
  • March 2016
  • February 2016
  • January 2016
  • December 2015
  • November 2015
  • October 2015
  • September 2015
  • August 2015
  • July 2015
  • June 2015
  • May 2015
  • April 2015
  • March 2015
  • February 2015
  • January 2015
  • December 2014
  • November 2014
  • October 2014
  • September 2014
  • August 2014
  • July 2014
  • June 2014
  • May 2014
  • April 2014
  • March 2014
  • February 2014
  • January 2014
  • December 2013
  • November 2013
  • October 2013
  • September 2013
  • August 2013
  • July 2013
  • June 2013
  • May 2013
  • April 2013
  • March 2013
  • February 2013
  • January 2013
  • December 2012
  • November 2012
  • October 2012
  • August 2012
  • July 2012
  • June 2012
  • May 2012
  • April 2012
  • March 2012
  • February 2012
  • January 2012
  • December 2011
  • November 2011
  • October 2011
  • September 2011
  • August 2011
  • July 2011
  • June 2011
  • May 2011
  • April 2011
  • March 2011
  • February 2011
  • January 2011
  • December 2010
  • October 2010
  • September 2010
  • July 2010
  • May 2010
  • April 2010
  • March 2010
  • February 2010
  • January 2010
  • November 2009

Copyright © 2021 Trudy Scott. All Rights Reserved. | Privacy | Terms of Use | Refund Policy