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toxoplasma gondii

A case of enterobiasis presenting as post-traumatic-stress-disorder / PTSD (i.e. a common and parasitic pinworm infection)

February 3, 2023 By Trudy Scott 11 Comments

case of enterobiasis

Enterobiasis (oxyuriasis) is a common infection in humans caused by Enterobius vermicularis (E. vermicularis), a human intestinal helminth. Because of the easy way of its transmission among people, it has an extremely high prevalence in overcrowded conditions, such as nurseries and primary schools. Oxyuriasis’s symptoms are extremely diverse in children, ranging from nausea, diarrhea, insomnia, irritability, recurrent cellulitis, loss of appetite, nightmares and endometritis.

Here we report a curious case of oxyuriasis in the settings of a refugee camp in Greece. The patient was a 10-year old Syrian female, who presented with unusual and vague symptoms like insomnia and irritability. Given the violent background of the Syrian warzone that the patient had escaped, she was firstly diagnosed with post traumatic stress disorder (PTSD) before eventually getting correctly diagnosed with enterobiasis.

This infection is the first documented case of enterobiasis in the settings of a refugee camp and can highlight the unsanitary living conditions that refugees have to endure in those camps.

The above is the abstract from a 2017 paper: A case of enterobiasis presenting as post-traumatic-stress-disorder (PTSD): a curious case of the infection with predominant mental health symptoms, presenting for the first time in the settings of a refugee camp

In addition to her symptoms of insomnia and irritability, she had a decreased appetite and mild abdominal (tummy) pain. She was also experiencing nausea and vomiting and had a slightly raised body temperature (subfebrile). She was severely malnourished and had lost 3kg/6.6lbs in 5 days.

Because of the violent nature of her situation she was initially seen by a psychologist but her symptoms worsened in a few days. When this young girl complained about itching in the perianal area (around her anus), the clinic reassessed her and scars around the anal area from the scratches.

They then confirmed enterobiasis/pinworm after using a piece of clear adhesive tape “to collect a specimen from the perianal surface of the girl, for three consecutive mornings … A microscopic examination showed the presence of oval shaped eggs, which is typical for the specific helminth [parasitic worm].”

She was treated with “two doses of albendazole, with each dose two weeks apart, in order to avoid reinfection …. And after a 3 month follow-up period, the patient remains asymptomatic without any signs of recurrence.”

An overview of pinworm infections, symptoms, tape test and treatment approaches

This WebMD article offers an overview of pinworm infections, the symptoms, the tape test and treatment approaches.

As you’ll read it’s not only a problem in refugee camps – it’s “very common in elementary school-aged children” and it’s the most common kind of worm infection in the United States. “Most of the time, pinworm infections don’t cause serious problems.” However, when one child (or adult) gets a pinworm infection it can easily be spread to the entire family.  The Syrian refugee paper mentions the whole family was tested.

Systemic infection: female health issues and gut health

The WebMD authors also state, “in rare cases, and especially if you have a lot of them, the pinworms can travel from the anal area up the vagina to the uterus, fallopian tubes, and around the pelvic organs. This can cause inflammation of the vagina (vulvovaginitis).”

I first learned about these serious systemic issues in women from naturopathic doctor Rachel Arthur at a conference in Australia. Contrary to the WedMD article, she believes this is not rare and more common than you’d expect, contributing to hormonal imbalances and even infertility.

The research confirms the impacts of pinworm on the gut, with reports of pinworm associated with appendicitis, pinworm in the liver, pinworms contributing to dysbiosis and pinworm being a factor in inflammatory bowel disease.

The WebMD article doesn’t mention the mental health symptoms and mechanisms but you can read more about that (and my interview with Dr. Jay Davidson) below.

Annual deworming and concerns about drug resistance?

I’m not going to get into anti-parasitic medications and herbal alternatives in this blog post – Dr. Jay talks about mimosa pudica seeds and Dr. Rachel recommends chondroitin sulfate – but do I want to mention that there are many public policy papers calling for annual deworming procedures for everyone. It’s also mentioned in the above Syrian refugee paper, as is hand-washing for prevention.

And many folks recall annual deworming concoctions as a child and did/do the same with their children.

There is, however, the concern about antiparasitic drug resistance similar to what is being seen with antibiotics and antiviral drugs.

If you are new to parasites and their impacts on mood issues, anxiety and insomnia and more

If you are new to parasites, here are some insights from an interview I did with Dr. Jay Davidson on The Anxiety Summit 5: Gut Brain Axis. The topic of our interview is – Parasites, Anxiety and TUDCA for Your Liver. He shares this:

The Greek meaning of parasite is one that sits at another’s table. So essentially think of a parasite as it’s taking things from you. It’s taking nutrients, it’s taking key things that your body needs and literally off of you, not to the point that it’s killing you because then you’re not a good host to give a good environment. So it’s basically just kind of sucking you dry.

We discussed symptoms individuals may experience: mood issues, anxiety and insomnia (especially around full moon). He shared that with insomnia “the big issue that I see is restless sleep where you toss, you turn, you wake often. You can’t just be relaxed when you sleep. Parasites get active when you go to bed. The more active they are within your body and the more you’re trying to calm down, the more your body is getting stressed out. This is where teeth grinding happens when you sleep.

This is very typical and likely the kinds of insomnia symptoms this young refugee girl experienced too. Pinworm is more active at night so the itching around her anus and the need to scratch would have affected her sleep too. This is a classic sign of pinworm.

With regards to anxiety and mood issues and possible mechanisms, Dr. Jay shares how parasites contribute to neurotransmitter imbalances:

Parasites will eat the protein you eat and not allow your body to break down that protein into amino acids. That’s why amino acid therapy can be so beneficial symptomatically and change people’s lives, because they’re getting these amino acids that they’re not getting when they have parasites.

When we digest protein, the amino acids are needed to help us make neurotransmitters. With his amino acid comments, he is making reference to my work with the amino acid tryptophan to support your low serotonin worry-type of anxiety symptoms and the amino acid GABA to support your low GABA physical-anxiety type symptoms. They are wonderful for quick relief of anxiety and mood symptoms, and even help sleep problems too. But as he says “you always want to make sure to go to the underlying cause to remove the parasitic infection.”

Other symptoms of parasitic infection that we discuss at length: restless legs and calf cramping, diarrhea, bowel urgency, SIBO (small intestinal bacterial overgrowth), vertical wrinkles above your mouth, nail-biting, food sensitivities, bed-wetting and night sweats. These are all symptoms that we need to look for and then consider stool testing and/or the sticky tape test/clear adhesive tape test for pinworm (as mentioned in the Syrian refugee paper and WebMD article above).

If you missed this interview and/or summit, you can find the purchase link on the above blog and here.

Tryptophan is not working (possibly because of parasites) and toxoplasma gondii (and GABA/anxiety)

Here is some additional reading on parasites on my site and in the literature:

  • Tryptophan doesn’t work, then it does and then it doesn’t: could it be hormonal shifts, dietary factors and/or parasites? As I share here, if you have a very pronounced shift in symptoms for 4-5 days around a full moon each month – more severe insomnia, more anxious, more depressed – I would want to check for parasites (as well as hormonal impacts and everything else covered on this blog).
  • Toxoplasma gondii: schizophrenia, bipolar disorder, OCD and unresolved anxiety? As I share in this blog, toxoplasma gondii is a microscopic parasite that infects cats and can be found in the soil – research shows it may be a factor in schizophrenia, bipolar disorder and OCD in susceptible individuals. Could toxoplasma gondii could be one of the root causes of unresolved anxiety? I believe so and feel it’s under-rated.
  • In this study, Toxoplasma gondii Infections Alter GABAergic Synapses and Signaling in the Central Nervous System, the authors share that “toxoplasma interferes with GABA signaling in the brain …playing a role in seizures and other neurological complications seen in Toxoplasma-infected individuals.” This particular parasite disrupts the workings of the glutamic acid decarboxylase 67 enzyme (GAD67), used to make GABA from glutamate, and very likely contributes to increased anxiety symptoms too.

Resources if you are new to using tryptophan, GABA and other amino acids as supplements

If you are new to using tryptophan, GABA or any of the other amino acids as supplements, here is the Amino Acids Mood Questionnaire from The Antianxiety Food Solution (you can see all the symptoms of neurotransmitter imbalances, including low GABA and low serotonin).

If you suspect low levels of any of the neurotransmitters and do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the practitioner/health team you or your loved one is working with.

There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, gluten, blood sugar control, sugar cravings, self-medicating with alcohol and more.

The book doesn’t include product names (per the publisher’s request) so this blog, The Antianxiety Food Solution Amino Acid and Pyroluria Supplements, lists the amino acids that I use with my individual clients and those in my group programs. You can find them all in my online store.

If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA QuickStart Program (if you have low GABA symptoms). This is a paid online/virtual group program where you get my guidance and community support.

If you are a practitioner, join us in The Balancing Neurotransmitters: the Fundamentals program. This is also a paid online/virtual program with an opportunity to interact with me and other practitioners who are also using the amino acids.

If you or a family member have had a pinworm infection, what symptoms did you experience and was the entire family affected?

Have you had hormonal and/or pelvic issues and/or gut issues as a result of systemic infection with pinworm?

How have other parasitic infections impacted your health?

How familiar are you with the fact that pinworm and other parasites can affect your mood, anxiety and sleep, as well as cause gut issues?

If you’re interested in learning more about testing and herbal protocols please let me know. If you’d like to share what has worked for you please do share too.

If you have other questions and feedback please share them here too.

Filed Under: Anxiety, Gut health, Insomnia, Parasites, PTSD/Trauma Tagged With: amino acids, anxiety, diarrhea, Enterobiasis, female health, GABA, insomnia, irritability, itching anal area, loss of appetite, mental health, mood, nausea, Nightmares, parasite, parasitic, pinworm, post-traumatic-stress-disorder, PTSD, Syrian, tape, the GABA Quickstart online program; and Balancing Neurotransmitters: the Fundamentals program for practitioners, toxoplasma gondii, tryptophan

Parasites, heavy metals and Lyme disease on the Parasite Summit

September 10, 2017 By Trudy Scott 4 Comments

Here are a few snippets from some of the interviews on the Parasite Summit:

The Trio of Parasites, Heavy Metals and Lyme Disease by Dr. Jay Davidson 

from what we understand research wise, Lyme disease, which is technically a bacteria or spirochete, has been shown to live inside of certain nematodes, which is essentially a type of parasite like a roundworm. So parasites can actually house Lyme disease, or bacteria, or other viruses, or other bacteria. And then, parasites are also a huge sponge for absorbing heavy metals.

And here’s what’s really crazy to think about. Parasites absorb heavy metals. So if you run a test and think, “Oh, man, I must have a ton of heavy metals because Dr. Jay and Dr. Scott are saying heavy metals are like this big thing,” and all of a sudden you have like no heavy metals show up or even false lows, and let’s say you “ran the test right,” it could mean that you also have a massive parasite issue because parasites absorb heavy metals. And if you didn’t deal with the parasites, then the heavy metals are still in the parasite, which then means that, from a testing standpoint, can still come up negative.

Digestion Strategies for Parasite Prevention by Dr. David Jockers

Now, somebody that does have their gallbladder taken out, you’re still producing bile. You just can’t produce as much. And so ultimately, therefore, you’re going to be at a much greater risk of developing something like a parasitic overgrowth if you don’t already have one. Which is typically one of the problems when you do have a sluggish gallbladder, oftentimes, it’s associated with a parasitic overgrowth or some sort of bacterial overgrowth in your small intestine.

I think it has to do with the ability of bile to be an emulsifier. Okay. So not only is it good for breaking up fatty acids in there, which is super key for digestion there, but the outer membrane of a lot of bacteria and microbes also is a fatty membrane. And so it can help break that up, as well. I believe that’s the main mechanism for it.

Parasites: Root Cause of Mystery Diseases by Ann Louise Gittleman

I think if any of your listeners have real difficulty in shaking off some of sort of illness, and if they’ve been feeling tired and listless and if they have a problem that the doctor simply can’t identify, then they have to begin to suspect that parasites could be the underlying cause. I also want them to remember that parasitic diseases don’t always happen to people just in other countries. The rate of parasite related disorders in our country is just about skyrocketing. And every single one of the 134 species that have been identified has been found on our shores.

The dark circles, the intermittent diarrhea, the persistent acne, anorexia, food intolerance, palpitations, puffy eyes, depression. Oh, that’s a good one. And there have been clinical studies from JAMA, as I recall, where they’ve connected toxoplasmosis with depression. So depression is big…who would connect it with a parasite? And the inability to relax and anxiety and being overly angry very oftentimes can have a toxoplasmosis connection.

I cover toxoplasma gondii in great detail in my interview on the Parasite Summit, as well as malaria and malaria medications.

At the Parasite Summit, experts will help you determine if parasites are silently impacting your health–they’re FAR MORE COMMON than you think! Parasites aren’t just found in third-world countries, millions are already infected in industrialized countries and could be silently hampering your health. Fortunately, with awareness and appropriate care, parasites can be prevented and treated, once detected.

If you’re struggling with any of the following, don’t miss this event:

  • Gastrointestinal: pain/cramps, excess gas, bloating, constipation/diarrhea
  • Infertility and hormone disorders
  • Skin issues: acne, itching, rashes
  • Mental health: depression, bipolar disorder, anxiety, OCD, schizophrenia
  • Challenges with autoimmune disease recovery (Toxoplasma gondii may be a factor in Hashimoto’s thyroiditis)

The Parasite Summit is online from September 11-18, 2017 and you can register here I hope you can join us!

Please share feedback and ask questions in the comments below.

Filed Under: Events, Parasites Tagged With: ann louise gittleman, anxiety, David Jockers, heavy metals, Jay Davidson, Lyme Disease, The Parasite Summit, toxoplasma gondii

Toxoplasma gondii: schizophrenia, bipolar disorder, OCD and unresolved anxiety?

August 14, 2017 By Trudy Scott 17 Comments

Toxoplasma gondii is a microscopic parasite that infects cats and can be found in the soil – research shows it may be a factor in schizophrenia, bipolar disorder and OCD in susceptible individuals. Could toxoplasma gondii could be one of the root causes of unresolved anxiety? I believe so and feel it’s under-rated.

This is the one of the parasitic infections I cover in an interview I did on The Parasite Summit.

Here are a few snippets from my interview:

A single-celled parasite called Toxoplasma gondii causes a disease known as toxoplasmosis.

Toxoplasma gondii is a microscopic parasite that infects cats and can be found in the soil. The infection can be acquired by ingesting contaminated food or water, by handling contaminated cat litter, or by transmission from mother-to-child.

According to the CDC – as of Mar 1, 2017 – in the United States it is estimated that 11% of the population 6 years and older have been infected with Toxoplasma. In various places throughout the world, it has been shown that up to 95% of some populations have been infected with Toxoplasma.

I love cats and have always been a cat person and pets are wonderful companions helping many of us humans recovering from PTSD and trauma – but we always need to dig deeper:

  • some individuals don’t respond as well to dietary changes, brain chemical balancing and addressing other biochemical/nutritional factors
  • I’m always looking for root possible causes. I’ve identified 70+ causes of anxiety and one of them is parasites
  • any parasite could be a factor – it causes stress and inflammation in the body, and we may see high cortisol leading to increased anxiety, insomnia and inflammation
  • could toxoplasma gondii could be one of the root causes of unresolved anxiety? I believe so and feel it’s under-rated – and believe we’ll be hearing more about it as more research comes out

I discuss this review paper published this year: Is Toxoplasma gondii a Trigger of Bipolar Disorder?

The association between T. gondii and schizophrenia/schizoaffective disorder is one of the most studied links between one pathogen and a psychiatric disorder.

However, growing emerging evidence has also documented an association between latent toxoplasmosis and the risk of [bipolar disorder] and suicidal/aggressive behaviors. T. gondii infection, as previously suggested for schizophrenia, may contribute to the onset and the progressive course of the disease interacting with genetic hereditary predisposing factors, as well as affecting neurotransmitter systems and immune responses, which have recently been shown to be closely linked to the pathogenesis of BD and its medical comorbidities.

The link between this parasite and psychiatric disorders could be also explained by its ability to influence neurotransmitter pathways. Indeed, T. gondii has been shown to increase dopamine levels, as well as to modulate serotonin, gamma-aminobutyric acid (GABA) and glutamate signaling.

With the impacts on neurotransmitters it’s clear how this parasite could directly trigger anxiety, panic attacks, fears, worry and even OCD. I cover this and more (malaria and malaria medications too) in my interview and book.

Parasites may be silently impacting your health and they’re FAR MORE COMMON than you think! Parasites aren’t just found in third-world countries, millions are already infected in industrialized countries and parasites could be silently hampering your health. Fortunately, with awareness and appropriate care, parasites can be prevented and treated, once detected.

If you’re struggling with any of the following, it may be worth looking into parasites:

  • Gastrointestinal: pain/cramps, excess gas, bloating, constipation/diarrhea
  • Infertility and hormone disorders
  • Skin issues: acne, itching, rashes
  • Mental health: depression, bipolar disorder, anxiety, OCD, schizophrenia
  • Challenges with autoimmune disease recovery (Toxoplasma gondii may also be a factor in Hashimoto’s thyroiditis)

Please share feedback and ask questions in the comments below.

Filed Under: Anxiety and panic, Events, Parasites Tagged With: anxiety, bipolar disorder, cats, dopamine, GABA, hashimoto's thyroiditis, OCD, parasite, schizophrenia, serotonin, The Parasite Summit, toxoplasma gondii, Trudy Scott

The Anxiety Summit – The Parasite/Anxiety Connection

May 9, 2015 By Trudy Scott 46 Comments

 

Ann Louise Gittleman PhD, CNS, author of The Fat Flush Plan and Guess What Came to Dinner, was interviewed on the Anxiety Summit by host of the Anxiety Summit, Trudy Scott, Food Mood Expert and Nutritionist, author of The Antianxiety Food Solution.

The Parasite/Anxiety Connection

  • How common are parasites and how do we become infected (even if we live in a first world country)
  • How do parasites contribute to anxiety and depression and even schizophrenia
  • Other symptoms of a parasitic infection
  • How to avoid being exposed to parasites
  • How to test for parasites and how do we get rid of the parasite/s

Here are some gems from our interview:

Parasitic infections in the USA are far more common than you would expect – in fact the estimates are that 1 in every 3 people have a parasite or more than one

Parasites can contribute to or cause anxiety and fear by altering “hormonal and neurotransmitter communication and/or direct interference with the neurons and brain regions that mediate behavioural expression”

According to folklore, parasites are more active around the full moon, so testing and treating around this time may yield better results

Toxoplasma gondii is one parasite that has been researched a great deal and is one that has big implications for anxiety and other mood conditions, especially schizophrenia.

Ann Louise shared this interesting article from Scientific American called Toxoplasma’s Dark Side: The Link Between Parasite and Suicide

In 2003, E. Fuller Torrey of the Stanley Medical Research Institute in Bethesda, Maryland his colleagues noted a link between Toxoplasma and schizophrenia – specifically, that women with high levels of the parasite were more likely to give birth to schizophrenics-to-be

scientists have discovered a link between suicide and parasite infection

In 2006, researchers linked Toxoplasma infection to neuroticism in both men and women.

When we are infected with a parasite like Toxoplasma gondii, our immune system goes on the offensive, producing a group of molecules called cytokines that activate various immune cell types. The exact mechanism by which cytokines cause depression and other mental illnesses is poorly understood, but we do know they are able to pass the blood-brain barrier and alter neurotransmitters like serotonin and dopamine in the brain.

Here is the parasite testing and products we discussed:  

The Expanded GI panel (for testing)

Colon Cleaning kit with Verma-Plus and Para- Key (together with a probiotic)

Verma-Plus contains the Native American herb called Centaury (aerial portion) (Centaurium erythraea)

It seems to have antimicrobial properties too: Volatile organic compounds from Centaurium erythraea Rafn (Croatia) and the antimicrobial potential of its essential oil.

And gastroprotective effects: Gastroprotective effect of small centaury (Centaurium erythraea L) on aspirin-induced gastric damage in rats.

We also talked about using filtered water for washing fruits and vegetables and this is the water filter Ann Louise recommends: Countertop Ultra-Ceramic Water Filter. “It purifies your tap water for the removal of incoming contaminants including parasites, chlorine, chloramines, heavy metals, cloudiness and sediment. The ceramic filter also inhibits the growth of bacteria”

Ann Louise has written many wonderful books.  Here are three of them that were mentioned in this interview:

Guess What Came to Dinner? Parasites and Your Health (this is the book about parasites)

Ann Louise Gittleman_guess what came to dinner

 

 

 

 

 

 

 

 

Before the Change: Taking Charge of Your Perimenopause (this is the one that helped me so much when I was in my late thirties and having perimenopausal symptoms – with the zinc, vitamin B6 and evening primrose oil )

Ann Louise Gittleman_before the change

 

 

 

 

 

 

 

 

The Fat Flush Plan (this is one of many her classic weight loss books)

AnnLouiseGittleman_fat flush plan

 

 

 

 

 

 

 

 

Here is her gift: a 50-Page Report on Parasites – Still the Greatest Masqueraders of All Time

If you are not already registered for the Anxiety Summit you can get live access to the speakers of the day here: www.theAnxietySummit.com

Missed this interview or can’t listen live? Or want this and the other great interviews for your learning library? Purchase the MP3s or MP3s + transcripts and listen when it suits you.

You can find your purchasing options here: Anxiety Summit Season 1, Anxiety Summit Season 2, and Anxiety Summit Season 3.

Filed Under: Antianxiety, Parasites, Testing, The Anxiety Summit 3 Tagged With: ann louise gittleman, parasites, perimenopause, schizophrenia, the anxiety summit, toxoplasma gondii, Trudy Scott

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