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Anxiety and Hypoglycemia Symptoms Improve with Diet Modification

August 12, 2016 By Trudy Scott 15 Comments

strawberry-smoothie

A paper published by the Canadian College of Naturopathic Medicine last month supports what I see with my clients on a daily basis: when it comes to anxiety caused by low blood sugar (or hypoglycemia) the correct diet can have a huge impact. And this means is the inclusion of enough protein, fats and fiber, especially at breakfast.

Here is the abstract from the paper: Generalized Anxiety Disorder and Hypoglycemia Symptoms Improved with Diet Modification

Observational evidence suggests that a relationship may exist between high glycemic index diets and the development of anxiety and depression symptoms; however, as no interventional studies assessing this relationship in a psychiatric population have been completed, the possibility of a causal link is unclear.

AB is a 15-year-old female who presented with concerns of generalized anxiety disorder and hypoglycemia symptoms. Her diet consisted primarily of refined carbohydrates. The addition of protein, fat, and fiber to her diet resulted in a substantial decrease in anxiety symptoms as well as a decrease in the frequency and severity of hypoglycemia symptoms.

A brief return to her previous diet caused a return of her anxiety symptoms, followed by improvement when she restarted the prescribed diet.

This case strengthens the hypothesis that dietary glycemic index may play a role in the pathogenesis or progression of mental illnesses such as generalized anxiety disorder and subsequently that dietary modification as a therapeutic intervention in the treatment of mental illness warrants further study.

Here are some details about this case report for AB, who was a 15-year-old female student of south-Asian descent:

  • she had anxiety (rated as 8/10 with 10 being the highest level of anxiety), worried excessively, experienced heart palpitations, shakiness, discomfort in her stomach, and muscle tension and often missed school because of how she felt
  • she experienced symptoms of hypoglycemia/low blood sugar and when her blood sugar dipped too low she experienced muscle weakness, headaches, nausea, anxiety, and poor concentration
  • when she felt anxious she would eat she would eat chocolate, chips, fruit and when her blood sugar dipped she would eat a granola bar

As you can see from her typical daily diet she was eating mostly carbohydrates, with very little protein, fat or fiber:

  1. Breakfast: fruit smoothie containing fruit, fruit juice, and water.
  2. Morning snack: bagel with margarine.
  3. Lunch: pasta or white rice with vegetables.
  4. Afternoon snack: granola bar or cookies or gummy candies.
  5. After school meal: white pasta; it may include meat.
  6. Dinner: white rice or spaghetti; it may include meat.
  7. Evening snack: cookies and toast.
  8. Beverages: 2 liters of water, 1 cup of juice, 1 cup of lactose-free milk, and 1 cup of tea.

She made the following changes in her diet adding protein at breakfast, lunch, dinner and at snack time, and adding healthy fats like flax seeds, olive oil and nut butters:

  1. Breakfast: includes a smoothie containing fruit, water, 1 scoop of protein powder, and 1 tablespoon of flax seeds or olive oil.
  2. Lunch and dinner: include a serving of protein (meat, legume, and soy) and a serving of vegetables.
  3. Snacks: include protein when possible (e.g., apple with sunflower seed butter, vegetable sticks with hummus, and pumpkin seeds).
  4. Continue to eat carbohydrate-containing snacks as needed for the management of hypoglycemia symptoms.

Over a 4-week period she made a few simple dietary changes and saw profound results: her anxiety decreased significantly from 8/10 to 4 or 5/10, she had more energy, she had fewer headaches, better concentration and improved mood.

The interesting factor is that when she slipped up for a week and went back to her old diet she felt more anxious within a day, but felt better within 2 days of adding back protein, fats and fiber.

These results are very typical with my clients and getting a handle on stabilizing blood sugar is the first thing I do with all my clients. Believe it or not, for some people this is ALL they need to do. I would add that I recommend making these changes in conjunction with the removal of gluten and caffeine.

I also like to see animal protein (and fat) as part of the snacks: like grass-fed beef jerky, grass-fed beef sticks, boiled eggs or pemmican. AB was allergic to eggs, nuts, and fish so these were not an option for her. Soy is often as issue so would need to be watched.

So this case study supports the fact that we must not forget the basics like blood sugar control. It’s very common for me to get questions like this on my blog: “I’m anxious, which amino acid should I use?” I always reply: focus first on real whole food and eating to balance blood sugar, remove sugar, gluten and caffeine, and then look at doing a trial of one or more of the amino acids

I do like to make things easier for my clients and this is where an amino acid like glutamine is very helpful in terms of providing added blood sugar stability, a calming effect and help with gut healing

Adding the glutamine and also doing a trial of an amino acid like GABA Calm may get the anxiety down a few more notches because we are always aiming for zero.

Addressing adrenal issues (which are closely related to blood sugar issues), and of course addressing all the other possible factors like thyroid health, gut health, other food sensitivities and so on would be the next step.

Have you see the positive impacts of keeping your blood sugar stable? What makes the most impact for you?

If you are a practitioner, how do you help your clients or patients address blood sugar issues?

Filed Under: Antianxiety Tagged With: anxiety, Carbohydrate, fat, fatigue, GABA, glutamine, Headaches, Hypoglycemia, low blood sugar, protein

Pyroluria and chronic fatigue syndrome: is there a link?

January 16, 2015 By Trudy Scott 21 Comments

pyroluria and chronic fatigue

Last week I blogged about the social anxiety condition called pyroluria (Pyroluria, high mauve, pyrrole disorder, malvaria, elevated kryptopyrroles and social anxiety) and received some great comments on this and the other pyroluria blogs.

One question on this blog: The Anxiety Summit: How zinc and vitamin B6 prevent pyroluria and social anxiety was related to Chronic Fatigue Syndrome/CFS so I’ve decided to share this and some additional information I was able to find.

Hi Trudy, I’m calling from Melbourne Australia, I was wondering if you have had any of your clients present with Chronic Fatigue Syndrome as well as pyroluria. I have just recently been diagnosed with CFS, I also have ADHD. Someone on a CFS forum that I belong to told me about pyroluria and said it is common in ADHD and CFS sufferers. While the link between ADHD and pyroluria is well documented, I haven’t been able to find any information regarding a connection between Chronic Fatigue Syndrome and pyroluria. I notice that there is an overlap of symptoms in the two conditions. I have all of the symptoms of CFS and many of the symptoms of pyroluria. I’m very interested in hearing your views about CFS and how it relates to pyroluria if at all. — Tom

I was not aware of a CFS/pyroluria connection until now but see there is some research showing how CFS and mood disorders/anxiety can have related causes and one of them is inflammation:

An intriguing and hitherto unexplained co-occurrence: Depression and chronic fatigue syndrome are manifestations of shared inflammatory, oxidative and nitrosative (IO&NS) pathways

Low zinc is a factor in pyroluria and depression and of course we may also see low zinc in CFS:

Lower serum zinc in Chronic Fatigue Syndrome (CFS): relationships to immune dysfunctions and relevance for the oxidative stress status in CFS

I find this paper very interesting since many of these same nutrients are commonly low in folks with anxiety and depression: Nutritional strategies for treating chronic fatigue syndrome

A detailed review of the literature suggests a number of marginal nutritional deficiencies may have etiologic relevance. These include deficiencies of various B vitamins, vitamin C, magnesium, sodium, zinc, L-tryptophan, L-carnitine, coenzyme Q10, and essential fatty acids.

I’m surprised the above paper didn’t mention iron anemia.  This is very common with pyroluria.  This paper: Iron insufficiency and hypovitaminosis D in adolescents with chronic fatigue and orthostatic intolerance found this

In patients presenting with chronic fatigue and/or orthostatic intolerance, low ferritin levels and hypovitaminosis D are common

These are just a few of the links I found by doing a very quick pubmed search. There are likely many more.

Everything is so connected and inter-related! And it’s interesting how certain deficiencies can manifest in certain ways – one person may find themselves with a CFS diagnosis, someone else with arthritis and yet someone else with heart disease. I think we need to be thinking about addressing nutrient deficiencies, balancing biochemistry and getting healthy, perhaps more just than addressing a diagnosis.

If you score high on the Pyroluria Questionnaire I would suggest simply addressing the pyroluria which may have some ripple down effects and actually improve the symptoms of CFS.

Now the next post will have to dig into the link between ADHD and pyroluria. Stay tuned.

In the meantime, I’d love to see your comments/questions if you can relate to any of this. Also, please do share in the comments if you know you have pyroluria and find the nutrients have eliminated your social anxiety and inner tension symptoms, and have also helped your CFS.

 

Filed Under: Depression, Pyroluria, Stress Tagged With: ADHD, anxiety, fatigue, Inflammation, iron, pyroluria, zinc

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