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flavonoid

Apigenin, a flavonoid in parsley increases brain connections, reduces anxiety

December 25, 2015 By Trudy Scott 9 Comments

parsley

New research finds that a flavonoid called apigenin increases brain connections:

the flavonoid apigenin, a substance found in parsley, thyme, chamomile and red pepper, improves neuron formation and strengthens the connections between brain cells, new lab research demonstrates… and has potential to treat diseases like schizophrenia, depression, Alzheimer’s and Parkinson’s

Previous experiments with animals had already shown that substances from the same chemical group as the apigenin… positively affect memory and learning. Many studies highlight the potential of flavonoids to preserve and enhance brain function.

While the effectiveness of flavonoids for brain health is not an entirely new concept, this research is the first to show the positive effects of apigegin directly on human cells and the first to unraveling its mechanism.

The neurons that were treated with the apigenin flavonoid (API) show more formation of synapses (red) than the neurons that were not treated. You can see this in the image on the right.

Credit: Rehen et al.

 

The study concludes with this:

since flavonoids are present at high amounts in some foods, we can speculate that a diet rich in flavonoids may influence the formation of neurons and the way they communicate within the brain.

Yes! These are powerful foods and nutrients for brain health! And these flavonoids have been shown to specifically reduce anxiety too, as mentioned in this paper – Flavonoids and the central nervous system: from forgotten factors to potent anxiolytic compounds

A paper published in October 2015: Flavonoid nutraceuticals and ionotropic receptors for the inhibitory neurotransmitter GABA likens flavonoids to benzodiazapines:

A number of studies have likened flavonoids to the widely prescribed benzodiazepines as ‘a new family of benzodiazepine receptor ligands’.

It is time to consider flavonoids in their own right as important modulators of these vital [GABA] receptors in brain function.

So let’s eat parsley and get a decent serving size in a delicious salad. I’ve got the perfect recipe for you, created by Rebecca Katz, author of The Healthy Mind Cookbook. I interviewed her on the Anxiety Summit and this was our topic – Your Brain on Food: The Science and Alchemy of Yum for Alleviating Anxiety!

We talked about one of my favorite recipes from her book: a pomegranate olive mint salsa recipe 

When I read the ingredients list I was surprised about the quantity of parley and mint but followed the directions anyway and the end result is incredibly yum! We LOVE this recipe – it has become a standard in our home. We have had it with both salmon and with lamb chops (it’s the best mint “sauce” for lamb).

Enjoy and let us know what you think! If you have a recipe that uses parsley feel free to share a link or the recipe in the comments.

Filed Under: Antianxiety, Recipes Tagged With: apigenin, flavonoid, parsley, Rebecca Katz

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