{"id":8226,"date":"2019-03-22T14:00:05","date_gmt":"2019-03-22T21:00:05","guid":{"rendered":"https:\/\/www.everywomanover29.com\/blog\/?p=8226"},"modified":"2019-03-24T04:01:34","modified_gmt":"2019-03-24T11:01:34","slug":"case-study-bartonella-and-sudden-onset-adolescent-schizophrenia","status":"publish","type":"post","link":"https:\/\/www.everywomanover29.com\/blog\/case-study-bartonella-and-sudden-onset-adolescent-schizophrenia\/","title":{"rendered":"Case Study: Bartonella and Sudden-Onset Adolescent Schizophrenia"},"content":{"rendered":"<p><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter wp-image-8227\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella.png\" alt=\"\" width=\"940\" height=\"492\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella.png 940w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-300x157.png 300w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-768x402.png 768w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-610x319.png 610w\" sizes=\"(max-width: 940px) 100vw, 940px\" \/><\/p>\n<p>According to <a href=\"https:\/\/news.ncsu.edu\/2019\/03\/bartonella-schizophrenia\/\" target=\"_blank\" rel=\"noopener noreferrer\">a press release<\/a> from North Carolina State University, researchers share a case study describing an adolescent human patient diagnosed with rapid onset schizophrenia who was found instead to have a <em>Bartonella henselae<\/em> infection. This study adds to the growing body of evidence that <em>Bartonella<\/em> infection can mimic a host of chronic illnesses, including mental illness, and could open up new avenues of research into bacterial or microbial causes of mental disorders.<\/p>\n<p><em>Bartonella<\/em> is a bacteria most commonly associated with cat scratch disease, which until recently was thought to be a short-lived (or self-limiting) infection. There are at least 30 different known species of <em>Bartonella<\/em>, and 13 of those have been found to infect human beings. The ability to find and diagnose <em>Bartonella<\/em> infection in animals and humans \u2013 it is notorious for \u201chiding\u201d in the linings of blood vessels \u2013 has led to its identification in patients with a host of chronic illnesses ranging from migraines to seizures to rheumatoid illnesses that the medical community previously hadn\u2019t been able to attribute to a specific cause.<\/p>\n<p>In the case study published in the <a href=\"https:\/\/journals.sagepub.com\/doi\/10.1177\/1179573519832014\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Journal of Central Nervous Disease<\/em><\/a>, an adolescent with sudden onset psychotic behavior \u2013 diagnosed as schizophrenia \u2013 was seen and treated by numerous specialists and therapists over an 18-month period. All conventional treatments for both psychosis and autoimmune disorders failed. Finally, a physician recognized lesions on the patient\u2019s skin that are often associated with <em>Bartonella<\/em>, and the patient tested positive for the infection. Combination antimicrobial chemotherapy led to full recovery.<\/p>\n<p>According to the case report above, <a href=\"https:\/\/journals.sagepub.com\/doi\/10.1177\/1179573519832014\" target=\"_blank\" rel=\"noopener noreferrer\">Bartonella henselae Bloodstream Infection in a Boy With Pediatric Acute-Onset Neuropsychiatric Syndrome<\/a>, these are some of the many symptoms he experienced over the 18-month period:<\/p>\n<ul>\n<li><em>He reported feeling overwhelmed, confused, depressed, and agitated. <\/em><\/li>\n<li><em>He said that he was an \u201cevil, damned son of the devil\u201d and wanted to kill himself because he was afraid of his new-onset homicidal thoughts toward those he cared about<\/em><\/li>\n<li><em>Weeks after initial hospitalization in October, he became more dysfunctional; school was not possible; he developed progressively severe psychiatric symptoms including obsessional intrusive thoughts, phobias, irrational fears, emotional lability, unpredictable rage outbursts, and increased psychotic thinking. He believed that he had special powers and that a family cat wanted to kill him. <\/em><\/li>\n<li><em>By December 2015, his illness had progressed in severity, causing his mother to quit her job to provide full-time supervision. In addition to persecutory delusions related to his pets, he developed auditory, visual, and tactile hallucinations and began refusing to leave the house. <\/em><\/li>\n<li><em>In January 2016, following discharge after a week-long hospitalization, he developed non-specific somatic symptoms, including excessive fatigue, daily headaches, chest pains, shortness of breath (possible panic anxiety), and urinary frequency<\/em><\/li>\n<\/ul>\n<p>I suspect some of his later symptoms were related to side-effects from many of the medications he was prescribed over the course of his treatment. Some symptoms may also be attributed to withdrawal from some of these medications. One example mentioned in the case study was \u201c<em>abrupt withdrawal of clozapine and tramadol\u201d <\/em>where<em> \u201che experienced severe anorexia, nausea, and vomiting, which resulted in hospitalization and a 20.5-kg weight loss over 40\u2009days.\u201d <\/em>It\u2019s well- documented that <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8879889\" target=\"_blank\" rel=\"noopener noreferrer\"><u>withdrawal signs and symptoms of antipsychotic medications <\/u><\/a>such as clozapine<em> \u201cmay include insomnia, nausea, vomiting, anxiety, and agitation.\u201d<br \/>\n<\/em><\/p>\n<p>This figure lists the medications he was prescribed during his treatment. The pink area was during his psychotic 18-month period and the yellow area was during his antimicrobial treatment of the <em>Bartonella<\/em>.<\/p>\n<figure id=\"attachment_8230\" aria-describedby=\"caption-attachment-8230\" style=\"width: 580px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-8230 \" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-fig2.png\" alt=\"\" width=\"580\" height=\"651\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-fig2.png 800w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-fig2-267x300.png 267w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-fig2-768x862.png 768w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-fig2-610x685.png 610w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/><figcaption id=\"caption-attachment-8230\" class=\"wp-caption-text\">Figure 2. Drug administration timeline for the boy, reprinted <a href=\"https:\/\/journals.sagepub.com\/doi\/10.1177\/1179573519832014\" target=\"_blank\" rel=\"noopener noreferrer\">from the study<\/a><\/figcaption><\/figure>\n<p>The skin lesions or \u201cstretch mark-like\u201d lesions on his thigh (A) and armpit (B) are tell-tale signs of a <em>Bartonella<\/em> bacterial infection or neurobartonellosis. Here are photographs taken by his parents.<\/p>\n<figure id=\"attachment_8231\" aria-describedby=\"caption-attachment-8231\" style=\"width: 610px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-8231\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-fig3.png\" alt=\"\" width=\"610\" height=\"472\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-fig3.png 800w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-fig3-300x232.png 300w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-fig3-768x594.png 768w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella-fig3-610x472.png 610w\" sizes=\"(max-width: 610px) 100vw, 610px\" \/><figcaption id=\"caption-attachment-8231\" class=\"wp-caption-text\"><a href=\"https:\/\/journals.sagepub.com\/doi\/10.1177\/1179573519832014\" target=\"_blank\" rel=\"noopener noreferrer\">Also from the study<\/a><\/figcaption><\/figure>\n<p>A successful outcome for this young boy came about as a result of antimicrobial treatment in the way of antibiotics and antifungals. His skin lesions healed, his psychosis and other symptoms resolved, he was able to quit his psychiatric medications and go back to being a typical young boy. How wonderful for this young boy!\u00a0 And this gives me so much hope for others who may be in a similar situation and looking for solutions.<\/p>\n<p>Other than the hope I felt, these are my other thoughts that came to my mind as I read this case study:<\/p>\n<ul>\n<li>How many people are being prescribed psychiatric medications when they actually have an infection or physiological condition? The authors state: <em>&#8220;Beyond suggesting that Bartonella infection itself could contribute to progressive neuropsychiatric disorders like schizophrenia, it raises the question of how often infection may be involved with psychiatric disorders generally.&#8221;<\/em><\/li>\n<li>How can a young boy of this age be prescribed this many psychiatric medications over an 18-month period? I\u2019m sure his doctors were doing their best but what is it going to take for doctors to look for infectious (and\/or physiological or biological or nutritional or environmental) causes for psychiatric symptoms as the first approach or certainly at the same time in a situation like this where psychosis was a factor?<\/li>\n<li>What will it take for mainstream practitioners to get up to speed with this epidemic of Lyme disease? And when will testing for Lyme disease and co-infections be used by all doctors and not just Lyme-literate doctors and functional medicine doctors like Dr. Darin Ingels. the author of \u201cThe Lyme Solution.\u201d (Here is my <a href=\"https:\/\/www.everywomanover29.com\/blog\/the-lyme-solution-by-dr-darin-ingels\/\" target=\"_blank\" rel=\"noopener noreferrer\">review of his excellent book<\/a>.) It is worth noting that Dr. Ingels uses very successful treatments that are purely herbal, dietary and immune-supportive, and don\u2019t require antibiotics.<\/li>\n<\/ul>\n<p>We already know there is a huge psychiatric connection with Lyme disease and co-infections: anxiety, depression, panic attacks, and OCD too. This case adds to the evidence. Even though <a href=\"https:\/\/www.everywomanover29.com\/blog\/neuropsychiatric-lyme-disease-suruchi-chandra\/\" target=\"_blank\" rel=\"noopener noreferrer\">neuropsychiatric Lyme disease<\/a>\u00a0is well-recognized in the world of functional medicine, keep in mind that Lyme disease bacteria such as <em>Borrelia<\/em> and co-infections such as <em>Bartonella<\/em> are only one of many possible trigger\/root cause of symptoms like this young boy experienced.<\/p>\n<p>Other infectious causes of psychiatric conditions include chronic strep (in the case of <a href=\"https:\/\/www.everywomanover29.com\/blog\/kid-not-crazy-panspandas-awareness-day-2017\/\" target=\"_blank\" rel=\"noopener noreferrer\">PANDAS\/PANS<\/a>) and <a href=\"https:\/\/www.everywomanover29.com\/blog\/toxoplasma-gondii-schizophrenia-bipolar-disorder-ocd-unresolved-anxiety\/\" target=\"_blank\" rel=\"noopener noreferrer\">toxoplasma gondii<\/a>.<\/p>\n<p>Other physiological root causes of psychiatric conditions like schizophrenia, anxiety, bipolar disorder and depression could include a thyroid condition, heavy metal toxicity from say lead or mercury, mycotoxins, and even gluten.<\/p>\n<p>We need to be shouting case studies like this from the rooftops so more doctors, more psychologists, more functional medicine practitioners, and more parents are aware and start to look for infectious\/physiological\/biological\/nutritional\/environmental root causes.<\/p>\n<p>We appreciate those involved in publishing this case and the family for giving permission.\u00a0 Hopefully, case studies like these will drive future research and treatment approaches.<\/p>\n<p>What do you think and what came to your mind when you read this case study?<\/p>\n<p>Feel free to post your questions here too.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>According to a press release from North Carolina State University, researchers share a case study describing an adolescent human patient diagnosed with rapid onset schizophrenia who was found instead to have a Bartonella henselae infection. This study adds to the growing body of evidence that Bartonella infection can mimic a host of chronic illnesses, including [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":8227,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[1240],"tags":[46,1589,1590,1588,1587,1592,1591,1594,1593,115],"class_list":["post-8226","post","type-post","status-publish","format-standard","has-post-thumbnail","category-children","tag-anxiety","tag-bartonella","tag-bipolar-disorder-and-depression","tag-borrelia","tag-lyme","tag-neurobartonellosis","tag-psychiatric","tag-psychosis","tag-psychotic","tag-schizophrenia","entry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Case Study: Bartonella and Sudden-Onset Adolescent Schizophrenia - everywomanover29 blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.everywomanover29.com\/blog\/case-study-bartonella-and-sudden-onset-adolescent-schizophrenia\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Case Study: Bartonella and Sudden-Onset Adolescent Schizophrenia - everywomanover29 blog\" \/>\n<meta property=\"og:description\" content=\"According to a press release from North Carolina State University, researchers share a case study describing an adolescent human patient diagnosed with rapid onset schizophrenia who was found instead to have a Bartonella henselae infection. This study adds to the growing body of evidence that Bartonella infection can mimic a host of chronic illnesses, including [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.everywomanover29.com\/blog\/case-study-bartonella-and-sudden-onset-adolescent-schizophrenia\/\" \/>\n<meta property=\"og:site_name\" content=\"everywomanover29 blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/TrudyScottAntianxietyFoodSolution\" \/>\n<meta property=\"article:published_time\" content=\"2019-03-22T21:00:05+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2019-03-24T11:01:34+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2019\/03\/bartonella.png\" \/>\n\t<meta property=\"og:image:width\" content=\"940\" \/>\n\t<meta property=\"og:image:height\" content=\"492\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Trudy Scott\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@foodmoodexpert\" \/>\n<meta name=\"twitter:site\" content=\"@foodmoodexpert\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Trudy Scott\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/case-study-bartonella-and-sudden-onset-adolescent-schizophrenia\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/case-study-bartonella-and-sudden-onset-adolescent-schizophrenia\\\/\"},\"author\":{\"name\":\"Trudy Scott\",\"@id\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/#\\\/schema\\\/person\\\/0992b9ecc4de889bd46f1226dc787b5b\"},\"headline\":\"Case Study: Bartonella and Sudden-Onset Adolescent Schizophrenia\",\"datePublished\":\"2019-03-22T21:00:05+00:00\",\"dateModified\":\"2019-03-24T11:01:34+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/case-study-bartonella-and-sudden-onset-adolescent-schizophrenia\\\/\"},\"wordCount\":1145,\"commentCount\":26,\"image\":{\"@id\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/case-study-bartonella-and-sudden-onset-adolescent-schizophrenia\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/wp-content\\\/uploads\\\/2019\\\/03\\\/bartonella.png\",\"keywords\":[\"anxiety\",\"bartonella\",\"bipolar disorder and depression\",\"borrelia\",\"lyme\",\"neurobartonellosis\",\"psychiatric\",\"psychosis\",\"psychotic\",\"schizophrenia\"],\"articleSection\":[\"Children\\\/Teens\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/case-study-bartonella-and-sudden-onset-adolescent-schizophrenia\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/case-study-bartonella-and-sudden-onset-adolescent-schizophrenia\\\/\",\"url\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/case-study-bartonella-and-sudden-onset-adolescent-schizophrenia\\\/\",\"name\":\"Case Study: Bartonella and Sudden-Onset Adolescent Schizophrenia - 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