{"id":6299,"date":"2017-06-02T14:00:21","date_gmt":"2017-06-02T21:00:21","guid":{"rendered":"http:\/\/www.everywomanover29.com\/blog\/?p=6299"},"modified":"2017-06-02T12:31:34","modified_gmt":"2017-06-02T19:31:34","slug":"anxiety-ibs-sibo-breath-antibody-testing-mindd-2017","status":"publish","type":"post","link":"https:\/\/www.everywomanover29.com\/blog\/anxiety-ibs-sibo-breath-antibody-testing-mindd-2017\/","title":{"rendered":"Anxiety is a common symptom of IBS\/SIBO: breath and antibody testing at MINDD 2017"},"content":{"rendered":"<p><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter size-full wp-image-6301\" src=\"http:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/anxiety-ibs-sibo.jpg\" alt=\"\" width=\"940\" height=\"492\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/anxiety-ibs-sibo.jpg 470w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/anxiety-ibs-sibo-300x157.jpg 300w\" sizes=\"(max-width: 940px) 100vw, 940px\" \/><\/p>\n<p>I attended Dr. Nirala Jacobi\u2019s presentation on at MINDD 2017 practitioner training and here are some highlights from her presentation on SIBO (small intestine bacterial overgrowth) which is the leading cause of IBS and a major cause of leaky gut syndrome. It is the presence of an overgrowth of beneficial bacteria in the small intestine i.e. good bacteria in the wrong place.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-6304\" src=\"http:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo1.jpg\" alt=\"\" width=\"450\" height=\"259\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo1.jpg 450w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo1-300x173.jpg 300w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/p>\n<p>She shares that:<\/p>\n<blockquote>\n<p>Bacterial overgrowth has also been implicated in a host of other conditions such as developmental delay, fibromyalgia, interstitial cystitis, malabsorption syndromes and many more [such as anxiety and depression and even insomnia]. SIBO requires a methodical approach to testing and treatment in order to successfully re-establish a healthy digestive tract.<\/p>\n<\/blockquote>\n<p>And some of the typical symptoms SIBO patients experience:<\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-6305\" src=\"http:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo2.jpg\" alt=\"\" width=\"450\" height=\"261\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo2.jpg 450w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo2-300x174.jpg 300w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/p>\n<p>I was not familiar with all these prior surgical procedures being a possible cause but this makes sense. I\u2019ve added gastric bypass, appendix removal, endometrial surgeries, C-section and gallbladder removal (cholecystectomy) to my <a href=\"http:\/\/www.everywomanover29.com\/blog\/sibo-small-intestinal-bacterial-overgrowth-questionnaire\" target=\"_blank\" rel=\"noopener noreferrer\">SIBO questionnaire<\/a>.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-6306\" src=\"http:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo3.jpg\" alt=\"\" width=\"450\" height=\"263\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo3.jpg 450w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo3-300x175.jpg 300w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/p>\n<p>Other possible causes include certain medications, stress and anxiety (which affects how much HCl or stomach acid you produce and gut motility) and overconsumption of simple carbohydrates.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-6307\" src=\"http:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo4.jpg\" alt=\"\" width=\"450\" height=\"263\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo4.jpg 450w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo4-300x175.jpg 300w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/p>\n<p>Going back to the #1 possible cause i.e. post-infectious due to a stomach bug, the gastroenteritis and autoimmunity connection was presented. Bacteria which cause food poisoning produce a toxin called CdtB which is similar to human vinculin which is important for nerve function.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-6308\" src=\"http:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo5.jpg\" alt=\"\" width=\"450\" height=\"263\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo5.jpg 450w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo5-300x175.jpg 300w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/p>\n<p>Due to the similarity between CdtB and vinculin, the body produces anti-vinculin and anti- CdtB antibodies which lead to an auto-immune attack on the enteric nervous system. This causes damage to the MMC\/migrating motor complex and contributes to SIBO.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-6309\" src=\"http:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo6.jpg\" alt=\"\" width=\"450\" height=\"263\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo6.jpg 450w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/06\/sibo6-300x175.jpg 300w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/p>\n<p>A press release from Cedars-Sinai and Dr. Pimental: <a href=\"https:\/\/www.cedars-sinai.edu\/About-Us\/News\/News-Releases-2015\/Definitive-Tests-for-Irritable-Bowel-Syndrome-Developed-at-Cedars-Sinai.aspx\" target=\"_blank\" rel=\"noopener noreferrer\">Definitive Tests for Irritable Bowel Syndrome Developed at Cedars-Sinai<\/a>\u00a0announce the multicenter study validating the accuracy of the new blood tests:<\/p>\n<blockquote>\n<p>Dr. Pimentel and fellow researchers studied nearly 3,000 people, comparing IBS patients to those diagnosed with inflammatory bowel disease, celiac disease and those with no GI disease. The blood tests identified the two antibodies associated with IBS &#8211; anti-Cdtb and anti-vinculin &#8211; with greater than 90 percent certainty.<\/p>\n<p>The tests are marketed under the name IBSchek\u2122 and are produced by Commonwealth Laboratories Inc., in Salem, Massachusetts.<\/p>\n<\/blockquote>\n<p>This paper reports this autoimmunity connection: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25424202\" target=\"_blank\" rel=\"noopener noreferrer\">Autoimmunity Links Vinculin to the Pathophysiology of Chronic Functional Bowel Changes Following Campylobacter jejuni Infection in a Rat Model<\/a>\u00a0and this paper discusses the two tests: <a href=\"http:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0126438\" target=\"_blank\" rel=\"noopener noreferrer\">Development and Validation of a Biomarker for Diarrhea-Predominant Irritable Bowel Syndrome in Human Subjects<\/a><\/p>\n<p>These blood tests are available in the USA but are not yet available in Australia where Dr. Nirala Jacobi now lives and practices.<\/p>\n<p>Dr. Nirala Jacobi, BHSc, ND (USA) graduated from Bastyr University in 1998 with a doctorate in naturopathic medicine. She practiced as a primary care physician in Montana for 7 years before arriving in Australia. Nirala is considered one of Australia\u2019s leading experts in the natural treatment of small intestine bacterial overgrowth (SIBO), a common cause of IBS. In 2014, she designed the SIBO Bi-Phasic Diet to aid practitioners in simplifying their treatment approach with their SIBO patients. She is the Chief Medical Officer and Director of <a href=\"https:\/\/sibotest.com\" target=\"_blank\" rel=\"noopener noreferrer\">SIBOtest.com<\/a>, an online breath testing service and educational portal for practitioners. She frequently lectures to national and international professional audiences on the topic of SIBO and founded the first Australian SIBO Summit in 2016 Nirala has had a busy private practice in Brisbane since 2008 and recently moved her clinic to Wilsons Creek in the beautiful northern rivers region of NSW, Australia.<\/p>\n<p>For SIBO breath testing services in all countries check out <a href=\"http:\/\/www.siboinfo.com\/testing.html\" target=\"_blank\" rel=\"noopener noreferrer\">the testing page on Dr. Siebecker\u2019s SIBOinfo site <\/a><\/p>\n<p>Keep in mind that most SIBO studies are on IBS. <a href=\"http:\/\/www.siboinfo.com\/associated-diseases.html\" target=\"_blank\" rel=\"noopener noreferrer\">According to Dr. Siebecker<\/a><\/p>\n<blockquote>\n<p>Drs. Pimentel and Lin originated the theory that SIBO is the underlying cause of IBS.\u00a0 As with all theories, there is debate and controversy about this idea, with many who agree and many who do not.\u00a0 One thing is certainly clear, the symptoms of SIBO overlap with those of IBS and a large percentage of IBS sufferers test positive for SIBO.\u00a0 One study by Dr Pimentel and team, showed <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12591062\" target=\"_blank\" rel=\"noopener noreferrer\">SIBO in up to 84% of IBS patients<\/a>, though the percentage has been lower in other studies, with an average of 60%.<\/p>\n<\/blockquote>\n<p>Here is the most recent study showing the mental health effects of IBS (which we could presumably extrapolate to SIBO and confirm with the testing discussed above) &#8211; <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28460516\" target=\"_blank\" rel=\"noopener noreferrer\">Neuroendocrine Dysregulation in Irritable Bowel Syndrome Patients: A Pilot Study<\/a><\/p>\n<blockquote>\n<p>Irritable bowel syndrome (IBS) is a multifactorial disorder, involving dysregulation of brain-gut axis<\/p>\n<p>Prevalent psychological symptoms in IBS were maladjustment (60%), trait (40%) and state (17%) anxiety, obsessive compulsive-disorders (23%), and depressive symptoms (23%).<\/p>\n<\/blockquote>\n<p>If you are not getting anxiety symptom resolution with dietary changes, the use of targeted individual amino acid, adrenal support, addressing dysbiosis and other biochemical approaches it\u2019s time to work with a practitioner to rule out or address SIBO as a causal factor.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>I attended Dr. Nirala Jacobi\u2019s presentation on at MINDD 2017 practitioner training and here are some highlights from her presentation on SIBO (small intestine bacterial overgrowth) which is the leading cause of IBS and a major cause of leaky gut syndrome. It is the presence of an overgrowth of beneficial bacteria in the small intestine [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[51,517],"tags":[1038,1096,1097,474],"class_list":["post-6299","post","type-post","status-publish","format-standard","category-events","category-sibo","tag-mindd","tag-nirala-jacobi","tag-sbi","tag-sibo","entry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Anxiety is a common symptom of IBS\/SIBO: breath and antibody testing at MINDD 2017 - everywomanover29 blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.everywomanover29.com\/blog\/anxiety-ibs-sibo-breath-antibody-testing-mindd-2017\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Anxiety is a common symptom of IBS\/SIBO: breath and antibody testing at MINDD 2017 - everywomanover29 blog\" \/>\n<meta property=\"og:description\" content=\"I attended Dr. Nirala Jacobi\u2019s presentation on at MINDD 2017 practitioner training and here are some highlights from her presentation on SIBO (small intestine bacterial overgrowth) which is the leading cause of IBS and a major cause of leaky gut syndrome. 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Trudy is the author of The Antianxiety Food Solution: How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood and End Cravings and host of The Anxiety Summit now in its 6th season and called a \u201cbouquet of hope.\u201d Trudy is passionate about sharing the powerful food mood connection because she experienced the results first-hand, finding complete resolution of her anxiety and panic attacks.\",\"url\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/author\\\/everywomanover29\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Anxiety is a common symptom of IBS\/SIBO: breath and antibody testing at MINDD 2017 - everywomanover29 blog","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.everywomanover29.com\/blog\/anxiety-ibs-sibo-breath-antibody-testing-mindd-2017\/","og_locale":"en_US","og_type":"article","og_title":"Anxiety is a common symptom of IBS\/SIBO: breath and antibody testing at MINDD 2017 - everywomanover29 blog","og_description":"I attended Dr. Nirala Jacobi\u2019s presentation on at MINDD 2017 practitioner training and here are some highlights from her presentation on SIBO (small intestine bacterial overgrowth) which is the leading cause of IBS and a major cause of leaky gut syndrome. 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