{"id":5676,"date":"2017-01-20T14:00:06","date_gmt":"2017-01-20T22:00:06","guid":{"rendered":"https:\/\/www.everywomanover29.com\/blog\/?p=5676"},"modified":"2020-03-06T08:27:12","modified_gmt":"2020-03-06T16:27:12","slug":"seriphos-original-formula-anxiety-insomnia-cortisol","status":"publish","type":"post","link":"https:\/\/www.everywomanover29.com\/blog\/seriphos-original-formula-anxiety-insomnia-cortisol\/","title":{"rendered":"Seriphos Original Formula is back: the best product for anxiety and insomnia caused by high cortisol"},"content":{"rendered":"<figure id=\"attachment_5677\" aria-describedby=\"caption-attachment-5677\" style=\"width: 470px\" class=\"wp-caption aligncenter\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-5677 size-full\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/01\/seriphos.jpg\" width=\"470\" height=\"240\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/01\/seriphos.jpg 470w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/01\/seriphos-300x153.jpg 300w\" sizes=\"(max-width: 470px) 100vw, 470px\" \/><figcaption id=\"caption-attachment-5677\" class=\"wp-caption-text\">Seriphos \u201cOriginal Formula\u201d with a red triangle on the left side of the bottle (Photo credit: Drew Todd)<\/figcaption><\/figure>\n<p>Interplexus changed its proprietary formula for Seriphos, a phosphorylated serine product, sometime March\/April 2016. It was changed to a form which no longer worked for many people with the anxiety and insomnia that is associated with high levels of cortisol at night.<\/p>\n<p>Thanks to feedback from folks in my community I investigated and blogged about this here: <a href=\"https:\/\/www.everywomanover29.com\/blog\/seriphos-reformulated-high-cortisol\/\" target=\"_blank\" rel=\"noopener noreferrer\">Seriphos has been reformulated \u2013 what do I use to lower high cortisol?<\/a>, sharing information about labeling confusion and many possible alternatives. \u00a0I also looked into <a href=\"https:\/\/www.everywomanover29.com\/blog\/magnolia-officinalis-phellodendron-amurense-relora-cortisol-stress-anxiety\/\" target=\"_blank\" rel=\"noopener noreferrer\">Relora<\/a>, a standardized\/patented Magnolia bark extract and Phellodendron bark extract, as a very viable alternative.<\/p>\n<p>But I was hoping, as were many of you, that they\u2019d hear all the requests and complaints from their loyal users and practitioners like myself and bring back the original formula.<\/p>\n<p>This week a number of people in my community notified me that the original Seriphos is back so I reached out to Interplexus again. I had been watching their site and had not seen any announcement just a banner stating it\u2019ll be ready Dec 2016 (which is still on the site as of this writing). So I emailed Interplexus earlier this week:<\/p>\n<blockquote><p>Just checking to see if you have a status update on this please?\u00a0 When will it be ready and when can we expect to see it in online stores? Can it be purchased from Interplexus directly? Can you also please share how we&#8217;ll know it&#8217;s the new formulation and are you able to guarantee it\u2019s the exact same formula as before?<\/p><\/blockquote>\n<p>And the response from Interplexus:<\/p>\n<blockquote><p>Seriphos has been in stock for about 3 weeks now and is widely available online, we are suggesting retail customers search the product online and purchase from the most convenient retailer because at this time we [Interplexus] are wholesale only. However we will be venturing into retail in the future.<\/p>\n<p>The label now has a red triangle on the left side that states \u201cOriginal Formula.\u201d To avoid confusion we are asking that customers purchase from online stores that have the updated label. We can assure you that it is the exact same formula as before.<\/p><\/blockquote>\n<p>The Original Formula of Seriphos is now back! And we\u2019re thrilled! Thank you Interplexus!<\/p>\n<figure id=\"attachment_5678\" aria-describedby=\"caption-attachment-5678\" style=\"width: 424px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-5678 size-full\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/01\/seriphos-bottle-1.jpg\" width=\"424\" height=\"184\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/01\/seriphos-bottle-1.jpg 424w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/01\/seriphos-bottle-1-300x130.jpg 300w\" sizes=\"(max-width: 424px) 100vw, 424px\" \/><figcaption id=\"caption-attachment-5678\" class=\"wp-caption-text\">(Photo credit: Julie Matthews)<\/figcaption><\/figure>\n<p>This is what the old bottle looked like before it was reformulated. The label reads: Proprietary Blend 1000mg Phosphorylated Serine\/Ethanolamine.<\/p>\n<figure id=\"attachment_5679\" aria-describedby=\"caption-attachment-5679\" style=\"width: 400px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-5679 size-full\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/01\/seriphos-bottle-2.jpg\" width=\"400\" height=\"270\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/01\/seriphos-bottle-2.jpg 400w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2017\/01\/seriphos-bottle-2-300x203.jpg 300w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><figcaption id=\"caption-attachment-5679\" class=\"wp-caption-text\">(Photo credit: Drew Todd)<\/figcaption><\/figure>\n<p>This is the label from the \u201cOriginal Formula\u201d \u2013 the new Seriphos just reintroduced<\/p>\n<p>As you can see the new \u201cOriginal Formula\u201d has the red triangle on the front and the back also reads: Proprietary Blend 1000mg Phosphorylated Serine\/Ethanolamine.<\/p>\n<p>I\u2019m sharing all this and the images for a few reasons:<\/p>\n<ul>\n<li>There was some confusion with the labels when it was reformulated earlier in 2016 (you can see what I mean here)<\/li>\n<li>If you need it I want to make sure you get the correct one and<\/li>\n<li>In the last week I\u2019ve had three reports from people who have the \u201cOriginal Formula\u201d and feel it\u2019s not working as before.<\/li>\n<\/ul>\n<p>I\u2019m going to stay optimistic and hope they\u2019ll see results after another week of use (maybe 2 weeks tops), although in the past I have had many clients say they notice a difference in a few days.<\/p>\n<p>If you have new \u201cOriginal Formula\u201d and have started using it again and have observed it\u2019s not working as before here are a few things to consider:<\/p>\n<ul>\n<li>Give it a week or two to see if it\u2019s going to work for you<\/li>\n<li>Keep a food mood sleep log to make sure nothing else is affecting your anxiety and sleep (like accidental gluten exposure, caffeine, high FODMAPs food if you have SIBO<\/li>\n<li>Your cortisol high may have shifted in the time you weren\u2019t taking the old Seriphos pre-April 2016 and you may need to retest your salivary cortisol levels and adjust the timing accordingly<\/li>\n<li>Think back to try and figure out if anything else may have change between then and now (a new medication started, a medication stopped, new supplements, dietary changes etc)<\/li>\n<\/ul>\n<p>If this is the first time you\u2019re reading about Seriphos here is some additional information: If you have high nighttime cortisol (as measured by an adrenal saliva test) it can cause insomnia and anxiety. Using 1-3 x Seriphos about 1-3 hours before the high cortisol is the best way I know for lowering the high cortisol and providing relief.<\/p>\n<p>Here is some feedback from someone who <a href=\"https:\/\/www.everywomanover29.com\/blog\/tryptophan-melatonin-work-but-still-wake-up-at-4am\/\" target=\"_blank\" rel=\"noopener noreferrer\">commented on the blog<\/a>:<\/p>\n<blockquote><p>I have been tested for cortisol and I have extremely high levels day and night. The old Seriphos [pre-April 2016] was working for me to reduce the internal jitters which would wake me several times a night with heart pounding and adrenalin rushing. I do not have a problem turning my brain off going to sleep \u2013 just problems waking several hours later (sometimes several times a night) \u2013 sometimes not being able to get back to sleep because I am wide awake.<\/p><\/blockquote>\n<p>And feedback from Julie Matthews, Certified Nutrition Consultant, Author of\u00a0<a href=\"http:\/\/NourishingHope.com\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Nourishing Hope for Autism<\/em><\/a>\u00a0and founder of <a href=\"http:\/\/BioIndividualNutrition.com\" target=\"_blank\" rel=\"noopener noreferrer\">Bioindividual Nutrition Institute<\/a>:<\/p>\n<blockquote><p>Seriphos is the best thing I found to combat high cortisol levels in the evening. I don\u2019t need to take it every day, but if there is an event that gets my cortisol up such as: travel, speaking at a conference, or doing taiko too late at night, I could be awake for hours from high cortisol. When I take Seriphos, I can literally feel my system dramatically ratcheting down moment by moment and within an hour or less I am easily able to go to bed and sleep. I have tried other supplements and none of them work nearly as well as Seriphos for me. I\u2019m so glad the \u201cOriginal Formula\u201d is back.<\/p><\/blockquote>\n<p>If you do have the new \u201cOriginal Formula\u201d and used the old Seriphos pre-April 2016, have you started using it again? We\u2019d love to hear how you\u2019re doing and how it compares to the Seriphos pre-April 2016?<\/p>\n<p>If you\u2019re a practitioner and have used the old Seriphos pre-April 2016 with success for helping clients\/patients lower high cortisol we\u2019d love to hear your feedback on the new \u201cOriginal Formula.\u201d<\/p>\n<p>Thanks for the initial alert about the reformulation, thanks if you shared pictures with me, thanks if have been asking questions and sharing feedback here on the blog, and thanks if you contacted Interplexus! I love the community we are creating here!<\/p>\n<p>UPDATE 3\/7\/2020: The new \u201cOriginal Formula\u201d of Seriphos is the same as the old Seriphos pre-April 2016 and is working as it always did, helping to lower high cortisol levels in order to ease anxiety that is due to high cortisol and improve sleep issues that are caused by high night-time or early morning cortisol. (I\u2019ve been replying to comments to this effect but forgot to come back and update the blog.)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Interplexus changed its proprietary formula for Seriphos, a phosphorylated serine product, sometime March\/April 2016. It was changed to a form which no longer worked for many people with the anxiety and insomnia that is associated with high levels of cortisol at night. Thanks to feedback from folks in my community I investigated and blogged about [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[965],"tags":[46,304,152,908],"class_list":["post-5676","post","type-post","status-publish","format-standard","category-supplements","tag-anxiety","tag-cortisol","tag-insomnia","tag-seriphos","entry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Seriphos Original Formula is back: the best product for anxiety and insomnia caused by high cortisol - everywomanover29 blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.everywomanover29.com\/blog\/seriphos-original-formula-anxiety-insomnia-cortisol\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Seriphos Original Formula is back: the best product for anxiety and insomnia caused by high cortisol - everywomanover29 blog\" \/>\n<meta property=\"og:description\" content=\"Interplexus changed its proprietary formula for Seriphos, a phosphorylated serine product, sometime March\/April 2016. 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