{"id":4248,"date":"2016-03-04T14:00:26","date_gmt":"2016-03-04T22:00:26","guid":{"rendered":"https:\/\/www.everywomanover29.com\/blog\/?p=4248"},"modified":"2016-03-04T14:00:26","modified_gmt":"2016-03-04T22:00:26","slug":"alzheimers-inflammation-stress-candida-rudy-tanzi-ihs-2016","status":"publish","type":"post","link":"https:\/\/www.everywomanover29.com\/blog\/alzheimers-inflammation-stress-candida-rudy-tanzi-ihs-2016\/","title":{"rendered":"Alzheimer\u2019s disease, inflammation, stress and candida: Dr. Rudy Tanzi at IHS 2016"},"content":{"rendered":"<p><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter size-full wp-image-4250\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2016\/03\/ihs-1.jpg\" alt=\"ihs-1\" width=\"480\" height=\"360\" \/><\/p>\n<p>I spent last week in New York city at the <a href=\"http:\/\/www.ihsymposium.com\/\" target=\"_blank\">Integrative Healthcare Symposium<\/a>\u00a0Annual Conference listening to some truly brilliant speakers and would like to share some highlights from the wonderful presentation by Rudolph Tanzi, PhD : <strong>What Can Alzheimer\u2019s Disease Teach Us About the Brain, Mind, and Self? <\/strong><\/p>\n<p><a href=\"http:\/\/curealz.org\/people\/rudy-tanzi#sthash.CSQcoHXs.dpuf\" target=\"_blank\">Dr. Rudolph Tanzi<\/a>\u00a0is the Vice-Chair of Neurology and Director of the Genetics and Aging Research Unit at Massachusetts General Hospital, and serves as the Joseph P. and Rose F.\u00a0Kennedy Professor of Neurology\u00a0at Harvard Medical School.\u00a0<\/p>\n<p>Dr. Tanzi co-discovered three of the first Alzheimer\u2019s disease genes and has identified several others in the Alzheimer\u2019s Genome Project, which he directs. He also discovered the Wilson\u2019s disease gene and participated in the discovery of several other neurological disease genes.<\/p>\n<p>The <a href=\"http:\/\/www.massgeneral.org\/neurology\/researcher_profiles\/tanzi_rudolph.aspx\" target=\"_blank\">focus of his research<\/a>\u00a0is in identifying and characterizing the genetic and environmental factors involved in neurodegeneration in Alzheimer&#8217;s disease and autism.<\/p>\n<p>Dr. Tanzi shared this fundamental information:<\/p>\n<ul>\n<li><em>the Alzheimer\u2019s disease pathology begins in all of us after the age of 40<\/em><\/li>\n<li><em>two thirds of those with Alzheimer\u2019s disease are female <\/em><\/li>\n<li><em>and women are especially susceptible after menopause\u00a0\u00a0 <\/em><\/li>\n<li><em>head injuries increase the risk<\/em><\/li>\n<li><em>these genes predispose us to the disease: APP, PSEN1, PSEN2 and APOE<\/em><\/li>\n<\/ul>\n<p>Most of the above apply to me (I know I have the APOE gene) but I\u2019m less concerned about Alzheimer\u2019s disease that I have ever been and this is based on what was shared later in his presentation.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-4251\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2016\/03\/ihs-2.jpg\" alt=\"ihs-2\" width=\"400\" height=\"300\" \/><\/p>\n<p>Dr. Tanzi\u2019s whole presentation was fascinating and the section on fungi\/candida, although concerning, was promising because we can do something about candida. This is the paper he shared: <em><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26468932\" target=\"_blank\">Different Brain Regions are Infected with Fungi in Alzheimer&#8217;s Disease<\/a><\/em>\u00a0with this question: Are clinical microbial pathogens triggering Alzheimer\u2019s disease?<\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-4252\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2016\/03\/ihs-3.jpg\" alt=\"ihs-3\" width=\"400\" height=\"300\" \/><\/p>\n<p>It was really interesting to hear that<\/p>\n<ul>\n<li><em>the amyloid is an antimicrobial agent in the brain and provides protection against the candida\/fungi<\/em><\/li>\n<li><em>and that that the amyloid plaques also provide protection against Borellia, periodontal bugs, Herpes Simplex 1 and other infectious agents <\/em><\/li>\n<\/ul>\n<p>What was most encouraging was this:<\/p>\n<ul>\n<li>your brain can handle tons of amyloid plaques and tangles and yet not develop Alzheimer\u2019s disease.<\/li>\n<li>the big deciding factor seems to be inflammation<\/li>\n<li>\u201cresilient brains\u201d had plaques, no inflammation and no Alzheimer\u2019s disease!<\/li>\n<\/ul>\n<p>So these are some of my thoughts:<\/p>\n<ul>\n<li>Tanzi did share that many people with Alzheimer\u2019s disease suffer from depression and agitation. Here is <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26876501\" target=\"_blank\">a paper I retrieved<\/a>; it does state that depression is worse when benzodiazepines have been used and we know benzodiazepines have been found to contribute to dementia so we need to consider this too.<\/li>\n<li>We also know anxiety is a factor in Alzheimer\u2019s disease and <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26880859\" target=\"_blank\">this study<\/a>\u00a0\u201cshowed that anxiolytic behavior\u2026is predominantly due to cox-2 mediated neuroinflammation induced neurodegeneration in the brain.\u201d<\/li>\n<li>Some of the same underlying causes of anxiety and depression seem to be underlying factors when it comes to Alzheimer\u2019s disease \u2013 like candida and inflammation \u2013 and there is something we can do about this. We can get rid of the candida and can use natural methods to reduce inflammation starting with eating an anti-inflammatory diet with wild oily fish, no gluten, no sugar and reduced carbs. \u00a0\u00a0\u00a0<\/li>\n<\/ul>\n<p>Dr. Tanzi also shared these for preventing Alzheimer\u2019s disease:<\/p>\n<ul>\n<li><em>Social engagement<\/em> (this is why addressing <a href=\"https:\/\/www.everywomanover29.com\/blog\/pyroluria-mauve-pyrrole-malvaria-kryptopyrroles-social-anxiety\/\" target=\"_blank\">pyroluria\/social anxiety<\/a>\u00a0is important \u2013 interestingly zinc, vitamin B6 and evening primrose oil are anti-inflammatory)<\/li>\n<li><em>Learning new things<\/em><\/li>\n<li><em>Reducing emotional stress and deep sleep<\/em> (this is where my work with the <a href=\"https:\/\/www.everywomanover29.com\/blog\/which-amino-acids-for-anxiety-which-ones-how-long\/\" target=\"_blank\">amino acids<\/a>\u00a0comes in \u2013 interestingly I found <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26888940\" target=\"_blank\">this study<\/a>\u00a0that discusses how enhancing GABA signaling can prevent cognitive decline in mice with the apoE4 gene)<\/li>\n<li><em>Exercise <\/em>(also so beneficial in anxiety and depression)<\/li>\n<li><em>And nutrients like ashwaganda and cat\u2019s claw <\/em>(to address stress and kill infections\/candida)<\/li>\n<\/ul>\n<p>Clearly I have more reading and researching to do! As you can tell I love putting all the puzzle pieces together.<\/p>\n<p>I\u2019ve also got more to share from Dr. Tanzi\u2019s talk and will do so next week. Stay tuned for more information on his \u201cthree- dimensional human stem cell-derived neural culture system that recapitulates Alzheimer\u2019s disease plaque and tangle pathology.\u201d<\/p>\n<p>Feel free to ask questions and share your thoughts in the comments section.<\/p>\n<p>&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td style=\"padding: 5px; text-align: left; font-family: Verdana,Geneva,Tahoma,sans-serif; color: #333333; font-size: 12px;\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>I spent last week in New York city at the Integrative Healthcare Symposium\u00a0Annual Conference listening to some truly brilliant speakers and would like to share some highlights from the wonderful presentation by Rudolph Tanzi, PhD : What Can Alzheimer\u2019s Disease Teach Us About the Brain, Mind, and Self? Dr. Rudolph Tanzi\u00a0is the Vice-Chair of Neurology [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[389,51,191,39],"tags":[747,390,748,659,749,83],"class_list":["post-4248","post","type-post","status-publish","format-standard","category-candida","category-events","category-inflammation","category-stress","tag-alzheimers-disease","tag-candida-2","tag-dr-rudy-tanzi","tag-inflammation","tag-integrative-healthcare-symposium","tag-stress-2","entry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Alzheimer\u2019s disease, inflammation, stress and candida: Dr. Rudy Tanzi at IHS 2016 - 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