{"id":2930,"date":"2015-03-06T18:00:52","date_gmt":"2015-03-07T02:00:52","guid":{"rendered":"https:\/\/www.everywomanover29.com\/blog\/?p=2930"},"modified":"2015-03-06T18:02:08","modified_gmt":"2015-03-07T02:02:08","slug":"mthfr-and-methylation","status":"publish","type":"post","link":"https:\/\/www.everywomanover29.com\/blog\/mthfr-and-methylation\/","title":{"rendered":"MTHFR and methylation: mood, anxiety, depression, and resources"},"content":{"rendered":"<p><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter wp-image-2932 size-full\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2015\/03\/dna.jpg\" alt=\"\" width=\"500\" height=\"281\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2015\/03\/dna.jpg 500w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2015\/03\/dna-300x169.jpg 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/p>\n<p>Methylation polymorphisms (also called defects or mutations or SNPs) can impact mood. I\u2019d like to share a few studies on some of the mood issues, other health conditions where we may see impacts and some resources for you to learn more.<\/p>\n<p>If you have one of the MTHFR polymorphisms, the BH4 cycle may be affected and may impact how we make serotonin and dopamine. Here is some of the research:<\/p>\n<ul>\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23586533\" target=\"_blank\">Anxiety and schizophrenia<\/a><\/li>\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25173634\" target=\"_blank\">Depression<\/a><\/li>\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17074966\" target=\"_blank\">Bipolar disorder<\/a><\/li>\n<\/ul>\n<p>There is much evidence on the methylation polymorphisms and these health conditions:<\/p>\n<ul>\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25566964\" target=\"_blank\">Cancer<\/a><\/li>\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24746944\" target=\"_blank\">Fertility<\/a><\/li>\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25591425\" target=\"_blank\">Heart disease and stroke<\/a><\/li>\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25070812\" target=\"_blank\">Thyroid cancer<\/a><\/li>\n<\/ul>\n<p><strong>Resources for further learning<\/strong><\/p>\n<p>The two practitioners who I have learned the most from are Dr. Ben Lynch ND and Coleen Walsh, a nutritionist who has been dubbed the \u201cmethyl queen\u201d. \u00a0\u00a0\u00a0<\/p>\n<ul>\n<li>Ben Lynch ND: his website <a href=\"http:\/\/mthfr.net\/\">http:\/\/mthfr.net\/<\/a> and blog articles provide a wealth of information and he is very active on his Facebook page (<a href=\"https:\/\/www.facebook.com\/drbenjaminlynch\">https:\/\/www.facebook.com\/drbenjaminlynch<\/a>). I did his excellent 2 day professional training which he has available on this site. I also interviewed him on The Anxiety Summit and we talked about <a href=\"https:\/\/www.everywomanover29.com\/blog\/anxiety-biochemical-and-genetic-predispositions\/\" target=\"_blank\">GAD, MOAO and COMT polymorphisms<\/a><\/li>\n<\/ul>\n<ul>\n<li>Coleen Walsh, nutritionist, \u201cmethyl queen\u201d offers a <a href=\"https:\/\/www.everywomanover29.com\/blog\/mthfr-and-methylation-practitioner-training\/\" target=\"_blank\">professional MTHFR and Methylation training for practitioners<\/a> and a <a href=\"https:\/\/www.everywomanover29.com\/blog\/mthfr-workshop-for-layperson\/\" target=\"_blank\">MTHFR workshop for the layperson and every day mutant<\/a>. I highly recommend both of these.<\/li>\n<\/ul>\n<p>Just remember this great quote from Coleen Walsh during <a href=\"https:\/\/www.everywomanover29.com\/blog\/anxiety-summit-mthfr-and-your-mood\" target=\"_blank\">our interview on the Anxiety Summit<\/a>:<\/p>\n<blockquote>\n<p>Our DNA is not set in stone! Diet and lifestyle can go a long way to change our health destiny<\/p>\n<\/blockquote>\n<p>The good news is that we can change our health, our disease outcomes and how we feel by eating real whole good quality organic food, getting chemicals and toxins out of our diets and environment, reducing stress, supporting the liver and our natural detox processes.<\/p>\n<p>Certain key nutrients can also be very help for many people with polymorphisms. I\u2019ll share more on folate and other nutrients and other SNPs in a later blog post. I\u2019ll also share more on genetic testing.<\/p>\n<p>I\u2019d love to hear if you\u2019ve done genetic testing and how making changes (supplement, diet, lifestyle) have helped. Be sure to post questions too.<\/p>\n<table>\n<tbody>\n<tr>\n<td style=\"padding: 5px; text-align: left; font-family: Verdana,Geneva,Tahoma,sans-serif; color: #333333; font-size: 12px;\">\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Methylation polymorphisms (also called defects or mutations or SNPs) can impact mood. I\u2019d like to share a few studies on some of the mood issues, other health conditions where we may see impacts and some resources for you to learn more. If you have one of the MTHFR polymorphisms, the BH4 cycle may be affected [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[7,132,32,205,290,271],"tags":[292,495,291],"class_list":["post-2930","post","type-post","status-publish","format-standard","category-anxiety-and-panic","category-bipolar-disorder","category-cancer-3","category-depression-2","category-mthfr","category-the-anxiety-summit-1","tag-coleen-walsh","tag-methylation","tag-mthfr-2","entry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>MTHFR and methylation: mood, anxiety, depression, and resources - 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