{"id":11814,"date":"2024-09-06T14:00:02","date_gmt":"2024-09-06T21:00:02","guid":{"rendered":"https:\/\/www.everywomanover29.com\/blog\/?p=11814"},"modified":"2024-09-06T09:34:11","modified_gmt":"2024-09-06T16:34:11","slug":"im-anxious-about-gaba-side-effects-and-feel-like-adding-a-bit-of-tryptophan-before-increasing-gaba-to-avoid-overdoing-it-with-either-one","status":"publish","type":"post","link":"https:\/\/www.everywomanover29.com\/blog\/im-anxious-about-gaba-side-effects-and-feel-like-adding-a-bit-of-tryptophan-before-increasing-gaba-to-avoid-overdoing-it-with-either-one\/","title":{"rendered":"I\u2019m anxious about GABA side effects and feel like adding a bit of tryptophan before increasing GABA (to avoid overdoing it with either one)"},"content":{"rendered":"<p><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter size-full wp-image-11815\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/09\/anxious-gaba-side-effects.jpg\" alt=\"gaba side effects\" width=\"940\" height=\"492\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/09\/anxious-gaba-side-effects.jpg 940w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/09\/anxious-gaba-side-effects-300x157.jpg 300w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/09\/anxious-gaba-side-effects-768x402.jpg 768w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/09\/anxious-gaba-side-effects-610x319.jpg 610w\" sizes=\"(max-width: 940px) 100vw, 940px\" \/><\/p>\n<blockquote><p>I have symptoms from both low GABA and low serotonin on your questionnaire. So I suspect I need to supplement with both. The main issues I have (anxiety, panic) are common to both deficiencies. I took a trial dose of 1 Gaba Calm and it seemed to help a bit. Should one continue increasing the dose of GABA or introduce some tryptophan next?<\/p>\n<p>I am trying to avoid GABA side effects because now that I read your last post on tingling etc (which would be a huge trigger for me), I\u2019m anxious about that.<\/p>\n<p>I feel like adding a bit of tryptophan before increasing GABA and going up like that, one at a time. Versus going higher and higher with GABA since the symptoms are on both lists &#8211; in order to avoid overdoing it with one .<\/p>\n<p>Does that make sense or do you still recommend doing one at a time (I just read on one of your blog posts that one should try one amino acid first before introducing another one)? Thank you!<\/p><\/blockquote>\n<p>Liz asked this great question on one of the blogs where I discuss how there can be an extremely large variation in dosing for GABA and how too much can cause a niacin-like flush and tingling.<\/p>\n<p>Her concerns are very valid &#8211; especially for someone who is anxious &#8211; but I still recommend doing a trial of just one amino acid before introducing another. In today\u2019s blog I share why this is my recommendation and why sometimes there is an exception to this recommendation (and how best to implement it).<\/p>\n<h2>My recommendation and her results<\/h2>\n<p>Liz is correct, I do always recommend doing a trial of one amino acid at a time before introducing the next one. I confirmed that this is still my recommendation and also reminded her that when \u201c<em>one GABA Calm seems to help a bit<\/em>\u201d it\u2019s a positive sign. When I hear this it\u2019s a big clue that you are on track and the next step is to continue to increase the GABA to determine if you\u2019ll get even better results. I told her we are looking for a wow effect in a few days to weeks.<\/p>\n<p>In case you\u2019re wondering, she did increase just the GABA (without adding tryptophan) and shared &#8220;<em>I\u2019ve now increased to 2 GABA Calms and it helps a lot!<\/em>&#8221;<\/p>\n<p>With this kind of result she may decide to stay with just 2 GABA Calm or she may decide to increase yet again if this amount hasn\u2019t substantially reduced her low GABA symptoms of physical tension, anxious thoughts, self-medicating with sugar or alcohol to relax, feelings of panic, pain etc. You can see <a href=\"https:\/\/www.everywomanover29.com\/blog\/amino-acids-mood-questionnaire-from-the-antianxiety-food-solution\/\" target=\"_blank\" rel=\"noopener\">all the low GABA symptoms here<\/a>).<\/p>\n<p>As always, I also reminded her what when you are new to the amino acids and other anxiety nutrition solutions like eating real whole food, quality animal protein, fermented foods, organic produce, healthy fats, gluten\/sugar\/caffeine removal, eating for blood sugar control, addressing gut health and pyroluria, my book \u201c<a href=\"https:\/\/www.everywomanover29.com\/blog\/the-antianxiety-food-solution-by-trudy-scott\/\" target=\"_blank\" rel=\"noopener\">The Antianxiety Food Solution<\/a>\u201d is a great place to start. It\u2019s a comprehensive approach \u2013 amino acids AND diet.<\/p>\n<p>She has \u201c<em>been eating organic, gluten-free, whole foods for 10+ yrs\u201d <\/em>(this is a wonderful foundation). However the stress of the last few years has really gotten to her and she has been meaning to get my book to get some help with amino acids. Hopefully she now has a\u00a0 copy!<\/p>\n<h2>Why do I recommend doing a trial of one amino acid at a time before introducing the next one?<\/h2>\n<p>As she mentioned, she has overlaps with low GABA and low serotonin symptoms: \u201c<em>anxiety, panic.\u201d <\/em>This is not uncommon. Although they do differ &#8211; with low GABA it\u2019s more physical and with low serotonin it\u2019s more mental &#8211; it can often be challenging to figure out which neurotransmitter imbalance is the issue. Doing a trial of one of the amino acids and seeing\/feeling the results provides the answer.<\/p>\n<p>In this case, Liz discovered all or some of her anxiety was caused by low GABA levels. I say some, because it can be due to both low GABA and low serotonin. Once she has a good baseline of GABA and assuming she still has some lingering anxiety symptoms (and other low serotonin symptoms like PMS, anger, low mood, afternoon cravings etc &#8211; <a href=\"https:\/\/www.everywomanover29.com\/blog\/amino-acids-mood-questionnaire-from-the-antianxiety-food-solution\/\" target=\"_blank\" rel=\"noopener\">see them all here<\/a>), she would then trial tryptophan without changing GABA dosing.<\/p>\n<p>Laying in the tryptophan (after doing an initial trial) would help Liz know that low serotonin is also an issue for her.<\/p>\n<p>And it would have all been challenging to figure out what was doing what had she done some GABA and some tryptophan and then more GABA and then more tryptophan.<\/p>\n<h2>Too much GABA and the adverse effects<\/h2>\n<p>Liz was understandably concerned about potential adverse effects of using too much GABA after reading this blog post: <a href=\"https:\/\/www.everywomanover29.com\/blog\/how-much-gaba-should-i-use-for-my-anxiety-it-depends-on-your-unique-needs-and-there-is-an-extremely-large-variation-in-dosing\/\" target=\"_blank\" rel=\"noopener\">How much GABA should I use for my anxiety? It depends on your unique needs (and there is an extremely large variation in dosing)<\/a><em>.<\/em> (This is the blog she commented on)<\/p>\n<p>I\u2019ve also published these blogs with similar messages:<\/p>\n<ul>\n<li><a href=\"https:\/\/www.everywomanover29.com\/blog\/too-much-gaba-causes-a-tingling-niacin-like-flush-sensation-in-the-brain-and-body-its-awful-and-very-uncomfortable\/\" target=\"_blank\" rel=\"noopener\">Too much GABA causes a tingling niacin-like flush sensation (in the brain and body). It\u2019s awful and very uncomfortable!<\/a><\/li>\n<li><a href=\"https:\/\/www.everywomanover29.com\/blog\/high-dose-gaba-750-mg-caused-her-to-feel-anxious-and-nervous-with-feelings-of-panic-she-also-felt-agitated-flushed-and-hot\/\" target=\"_blank\" rel=\"noopener\">High dose GABA (750 mg) caused her to feel anxious and nervous with feelings of panic. She also felt agitated, flushed and hot<\/a><\/li>\n<\/ul>\n<p>Learning about adverse effects like this may make you feel more anxious rather than educated and empowered &#8211; hence her question about using tryptophan. However, too much tryptophan can also increase feelings of anxiousness and keep you awake (and it\u2019s going to complicate the trial).<\/p>\n<p>Knowing about vitamin C as an antidote often helps mitigate some of the anxious feelings but when it doesn\u2019t then there may be an exception.<\/p>\n<h2>Why there may be an exception to my recommendation (and how best to implement it).<\/h2>\n<p>Typically when someone has profound fears that hold them back and stop them from using any of the amino acids, my recommendation is always to start with serotonin support as it can allay fears, worry, obsessing and ruminations about possible adverse effects.<\/p>\n<p>In a situation like Liz describes, if anxious thoughts and worrying prevents her from increasing GABA, we would discuss all of the above and I\u2019d help her decide what to do next:<\/p>\n<ul>\n<li>Layer on tryptophan before she has found her ideal dose of GABA, without any change to GABA i.e. one change only. And then go from there to increase the GABA and eventually increase the tryptophan later if she needs to<\/li>\n<li>Stop GABA and switch to tryptophan only and then come back to GABA. It isn\u2019t ideal to lose the gains experienced, even when GABA only \u201c<em>seems to help a bit.\u201d<\/em><\/li>\n<\/ul>\n<p>The good news is that Liz felt comfortable enough increasing the GABA and saw the benefits. This may not be the case for everyone and the above are some options to consider.<\/p>\n<h2>A few GABA product options\u00a0 \u2013 a sublingual, a powder and a cream<\/h2>\n<div style=\"display: flex; align-items: center;\">\n<div style=\"width: 33%; padding: 1rem;\"><a href=\"https:\/\/us.fullscript.com\/welcome\/trudyscott\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" class=\"aligncenter wp-image-11485\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/02\/gaba-calm.png\" alt=\"gaba calm\" width=\"166\" height=\"280\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/02\/gaba-calm.png 206w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/02\/gaba-calm-178x300.png 178w\" sizes=\"(max-width: 166px) 100vw, 166px\" \/><\/a><\/div>\n<div style=\"width: 33%; padding: 1rem;\"><a href=\"https:\/\/us.fullscript.com\/welcome\/trudyscott\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" class=\"aligncenter wp-image-11486\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/02\/now-gaba-pure-powder.png\" alt=\"gaba pure poder\" width=\"178\" height=\"280\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/02\/now-gaba-pure-powder.png 252w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/02\/now-gaba-pure-powder-191x300.png 191w\" sizes=\"(max-width: 178px) 100vw, 178px\" \/><\/a><\/div>\n<div style=\"width: 33%; padding: 1rem;\"><a href=\"https:\/\/www.everywomanover29.com\/blog\/somnium-nighttime-gaba-cream-insomnia-anxiety-bloated-belly-muscle-spasms-ms-arfid-anorexia-alzheimers-and-autism\/\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-11572 \" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/04\/somnium-gaba-cream.jpeg\" alt=\"somnium gaba cream\" width=\"223\" height=\"187\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/04\/somnium-gaba-cream.jpeg 332w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2024\/04\/somnium-gaba-cream-300x251.jpeg 300w\" sizes=\"(max-width: 223px) 100vw, 223px\" \/><\/a><\/div>\n<\/div>\n<p>Liz used Source Naturals GABA Calm lozenges (a good low dose of 125 mg). It\u2019s one of the many products I recommend. Another one is Now GABA Powder (which does need to be measured out to provide a 125 mg typical starting dose). Keep in mind, some individuals need less to start.<\/p>\n<p>When using GABA powder I have clients use a handy mini measuring spoon <a href=\"https:\/\/amzn.to\/3Q94nsI\" target=\"_blank\" rel=\"noopener\">like this one<\/a>\u00a0(my Amazon link) and share more about <a href=\"https:\/\/www.everywomanover29.com\/blog\/how-to-accurately-measure-a-small-amount-of-powdered-gaba-and-other-gaba-options-when-gaba-calm-is-not-tolerated\/\" target=\"_blank\" rel=\"noopener\">how to measure out GABA powder on this blog<\/a>).<\/p>\n<p>For Source Naturals GABA Calm lozenges and Now GABA Powder:<\/p>\n<ul>\n<li>You can purchase these from my online store (Fullscript \u2013 only available to US customers \u2013 <a href=\"https:\/\/us.fullscript.com\/welcome\/trudyscott\" target=\"_blank\" rel=\"noopener\">use this link to set up an account<\/a>).<\/li>\n<li>If you\u2019re not in the US, you can purchase these at iherb (<a href=\"https:\/\/www.iherb.com\/?rcode=BAN2021\" target=\"_blank\" rel=\"noopener\">use this link to save 5%<\/a>).<\/li>\n<\/ul>\n<p>Somnium GABA Cream is available in the US and elsewhere with international shipping. Read <a href=\"https:\/\/www.everywomanover29.com\/blog\/somnium-nighttime-gaba-cream-insomnia-anxiety-bloated-belly-muscle-spasms-ms-arfid-anorexia-alzheimers-and-autism\/\" target=\"_blank\" rel=\"noopener\">more about the product<\/a>\u00a0and who may benefit from using a cream, and grab my coupon code to save 15%.<\/p>\n<h2>Additional resources when you are new to using GABA and other amino acids as supplements<\/h2>\n<p>As always, I use <a href=\"https:\/\/www.everywomanover29.com\/blog\/amino-acids-mood-questionnaire-from-the-antianxiety-food-solution\/\" target=\"_blank\" rel=\"noopener\">the symptoms questionnaire<\/a> to figure out if low low GABA or other neurotransmitter imbalances may be an issue.<\/p>\n<p>If you suspect low levels of any of the neurotransmitters and do not yet have my book, <a href=\"https:\/\/www.everywomanover29.com\/blog\/the-antianxiety-food-solution-by-trudy-scott\/\" target=\"_blank\" rel=\"noopener\">The Antianxiety Food Solution \u2013 How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings<\/a>, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the practitioner\/health team you or your loved one is working with.<\/p>\n<p>There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, gluten, blood sugar control (this is covered in an entire chapter too), sugar cravings, anxiety and mood issues.<\/p>\n<p>The book doesn\u2019t include product names (per the publisher\u2019s request) so this blog, <a href=\"https:\/\/www.everywomanover29.com\/blog\/amino-acids-pyroluria-supplements\/\" target=\"_blank\" rel=\"noopener\">The Antianxiety Food Solution Amino Acid and Pyroluria Supplements<\/a>, lists the amino acids that I use with my individual clients and those in my group programs.<\/p>\n<p>If, after reading this blog and my book, you don\u2019t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the <a href=\"https:\/\/www.anxietynutritioninstitute.com\/gabaquickstart\/\" target=\"_blank\" rel=\"noopener\">GABA QuickStart Program<\/a> (if you have low GABA symptoms). This is a paid online\/virtual group program where you get my guidance and community support.<\/p>\n<p>If you are a practitioner, join us in <a href=\"https:\/\/www.anxietynutritioninstitute.com\/balancingneurotransmitters\/\" target=\"_blank\" rel=\"noopener\">The Balancing Neurotransmitters: the Fundamentals<\/a> program. This is also a paid online\/virtual program with an opportunity to interact with me and other practitioners who are also using the amino acids.<\/p>\n<h2>Wrapping up and your feedback<\/h2>\n<p>I appreciate Liz for asking this question. I do hope this information has been helpful for you and for her too.<\/p>\n<p>Now I\u2019d love to hear from you &#8211; does any of this resonate with you? Have you felt anxious or fearful about increasing your dose of GABA? And how did you resolve it?<\/p>\n<p>If you\u2019re a practitioner is this how you advise your clients\/patients?<\/p>\n<p>Feel free to share and ask your questions below.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>I have symptoms from both low GABA and low serotonin on your questionnaire. So I suspect I need to supplement with both. The main issues I have (anxiety, panic) are common to both deficiencies. I took a trial dose of 1 Gaba Calm and it seemed to help a bit. Should one continue increasing the [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":11815,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[1172,663,1181,745],"tags":[794,46,75,3137,59,842,3136,3138,179,154,676,1936,80],"class_list":["post-11814","post","type-post","status-publish","format-standard","has-post-thumbnail","category-anxiety","category-gaba","category-serotonin","category-tryptophan","tag-amino-acid","tag-anxiety","tag-anxious","tag-avoid-overdoing-it","tag-gaba","tag-gaba-calm","tag-gaba-side-effects","tag-niacin-like-flush","tag-panic","tag-serotonin","tag-side-effects","tag-tingling","tag-tryptophan","entry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>I\u2019m anxious about GABA side effects and feel like adding a bit of tryptophan before increasing GABA (to avoid overdoing it with either one) - everywomanover29 blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.everywomanover29.com\/blog\/im-anxious-about-gaba-side-effects-and-feel-like-adding-a-bit-of-tryptophan-before-increasing-gaba-to-avoid-overdoing-it-with-either-one\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"I\u2019m anxious about GABA side effects and feel like adding a bit of tryptophan before increasing GABA (to avoid overdoing it with either one) - everywomanover29 blog\" \/>\n<meta property=\"og:description\" content=\"I have symptoms from both low GABA and low serotonin on your questionnaire. So I suspect I need to supplement with both. The main issues I have (anxiety, panic) are common to both deficiencies. I took a trial dose of 1 Gaba Calm and it seemed to help a bit. 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