{"id":10682,"date":"2022-10-14T14:00:14","date_gmt":"2022-10-14T21:00:14","guid":{"rendered":"https:\/\/www.everywomanover29.com\/blog\/?p=10682"},"modified":"2022-10-14T09:45:32","modified_gmt":"2022-10-14T16:45:32","slug":"lactium-alpha-s1-casein-hydrolysate-hydrolyzed-casein-for-lowering-high-cortisol-reducing-anxiety-and-improving-sleep","status":"publish","type":"post","link":"https:\/\/www.everywomanover29.com\/blog\/lactium-alpha-s1-casein-hydrolysate-hydrolyzed-casein-for-lowering-high-cortisol-reducing-anxiety-and-improving-sleep\/","title":{"rendered":"Lactium\u00ae (alpha-s1 casein hydrolysate\/hydrolyzed casein) for lowering high cortisol, reducing anxiety and improving sleep"},"content":{"rendered":"<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone size-full wp-image-10683\" src=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2022\/10\/lactium-anxiety.jpg\" alt=\"lactium cortisol anxiety\" width=\"940\" height=\"492\" srcset=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2022\/10\/lactium-anxiety.jpg 940w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2022\/10\/lactium-anxiety-300x157.jpg 300w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2022\/10\/lactium-anxiety-768x402.jpg 768w, https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2022\/10\/lactium-anxiety-610x319.jpg 610w\" sizes=\"(max-width: 940px) 100vw, 940px\" \/><\/p>\n<p>Lactium\u00ae is my second choice for lowering high cortisol and reducing the type of anxiety that we see when cortisol is high i.e. anxiety that feels like an adrenaline-type surge.\u00a0 It is especially helpful when cortisol is high as you wake up. This can be confirmed by a 4 collection saliva test. The reason why Lactium\u00ae is the best choice in a situation like this is because Seriphos (a phosphorylated serine product) is most effective for lowering high cortisol when it\u2019s used 3 hours before the high cortisol measurement and you can&#8217;t do this when anxiety and adrenaline-type surges happen on waking in the morning. This is where Lactium\u00ae shines. It also helps to reduce anxiety at other times in the day and to improve sleep.<\/p>\n<h2>The Lactium\u00ae research<\/h2>\n<p>There is research supporting the use of Lactium\u00ae for improving sleep, reducing anxiety and lowering high cortisol. The number of Lactium\u00ae studies are not extensive but the results are very promising and correlate with what we see clinically. Here are a few of them:<\/p>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15517308\/\" target=\"_blank\" rel=\"noopener\">Effects of a tryptic hydrolysate from bovine milk alphaS1-casein on hemodynamic responses in healthy human volunteers facing successive mental and physical stress situations<\/a><\/li>\n<\/ul>\n<p style=\"padding-left: 80px;\"><em>&#8220;The study subjects were (double blind) randomly allocated to ingest three times, 12 hours apart, two capsules containing either 200 mg of alphaS1-casein hydrolysate or bovine skimmed milk powder as a placebo.\u201d They were then subjected to successive stress situations. There was a significant decrease of plasma cortisol concentrations and heart rate remained stable in the Lactium\u00ae group. The study conclusion is as follows: \u201cOn the basis of blood pressure and cortisol changes, these results suggest an anti stress profile of this alphaS1-casein hydrolysate in human subjects.&#8221;<\/em><\/p>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31252661\/\" target=\"_blank\" rel=\"noopener\">A Double-Blind, Randomized, Placebo-Controlled Crossover Clinical Study of the Effects of Alpha-s1 Casein Hydrolysate on Sleep Disturbance<\/a><\/li>\n<\/ul>\n<p style=\"padding-left: 80px;\">48 participants exhibited mild to moderate degree of sleep disturbance and after 4 weeks of Lactium\u00ae use, <em>\u201coverall perceived sleep profiles in sleep diaries were significantly improved \u2026 represented by increased total sleep time and sleep efficiency, as well as decreased sleep latency and wake after sleep onset.\u201d It was concluded that Lactium\u00ae \u201cwas well tolerated and could improve sleep quality, with possible cumulative beneficial effects with long-term administration.\u201d<\/em><\/p>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35277011\/\" target=\"_blank\" rel=\"noopener\">Effect of Alpha-S1-Casein Tryptic Hydrolysate and L-Theanine on Poor Sleep Quality: A Double Blind, Randomized Placebo-Controlled Crossover Trial<\/a><\/li>\n<\/ul>\n<p style=\"padding-left: 80px;\">39 subjects were given a supplement containing Lactium\u00ae and theanine for four weeks. The authors concluded that \u201c<em>given its beneficial effects without notable adverse events, it would be advantageous to use these nutraceutical ingredients to promote better sleep quality<\/em>\u201d (and in a larger study).<\/p>\n<p>You\u2019ll see Lactium\u00ae referred to as alpha-s1 casein hydrolysate, hydrolyzed casein concentrate, and tryptic hydrolysate from bovine milk alphaS1-casein.<\/p>\n<p>INGREDIA of France manufactures Lactium and you will see some of the studies have been initiated and\/or co-authored by them.<\/p>\n<p>The product I use is called Biotics Research De-Stress. It contains 150mg Lactium\u00ae in one capsule. I\u2019ve had clients use 1-2 capsules at a time, based on symptoms and the relief they feel.<\/p>\n<h2>Lactium\u00ae works on GABAA receptors<\/h2>\n<p>What is really interesting is an animal study that reports Lactium\u00ae works on the GABAA receptor: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27401107\/\" target=\"_blank\" rel=\"noopener\">A tryptic hydrolysate from bovine milk \u03b1s1-casein enhances pentobarbital-induced sleep in mice via the GABAA receptor<\/a><\/p>\n<p>It was found that Lactium\u00ae \u201c<em>enhanced the sleep induced by pentobarbital sodium in mice. It also promoted slow-wave (delta) EEG activity in rats; a pattern indicative of sleep or relaxation<\/em>.\u201d The authors state that the effects are \u201cprobably mediated through the GABAA receptor-chloride ion channel complex.\u201d<\/p>\n<p>As you may already know, GABA is one of the amino acids I use extensively with folks with <a href=\"https:\/\/www.everywomanover29.com\/blog\/gaba-physical-tension-stiff-tense-muscles-type-anxiety\/\" target=\"_blank\" rel=\"noopener\">low GABA physical anxiety<\/a> and related sleep issues. There is also compelling research on the benefits of <a href=\"https:\/\/www.everywomanover29.com\/blog\/gaba-and-theanine-for-easing-anxiety-improving-sleep-and-supporting-immunity\/\" target=\"_blank\" rel=\"noopener\">GABA and theanine for improving sleep and easing anxiety<\/a>.<\/p>\n<p>I have found that many of my clients do well on both GABA (when GABA levels are low) and Lactium\u00ae (when cortisol is high).\u00a0 Lactium\u00ae can be used in the daytime and at night when cortisol is high (and so can Seriphos).<\/p>\n<h2>Seriphos and other ways to lower high cortisol<\/h2>\n<p>As I mentioned above, Seriphos is my first choice for lowering high cortisol and easing this type of anxiety, especially when cortisol is high during the night. Seriphos is a phosphorylated serine product and I find it much more effective than regular phosphatidylserine products.<\/p>\n<p>If you\u2019re new to Seriphos here is my blog post &#8211; <a href=\"https:\/\/www.everywomanover29.com\/blog\/seriphos-original-formula-anxiety-insomnia-cortisol\/\" target=\"_blank\" rel=\"noopener\">Seriphos Original Formula is back: the best product for anxiety and insomnia caused by high cortisol<\/a><\/p>\n<p>There are other ways to lower cortisol too:<\/p>\n<ul>\n<li>Relora &#8211; <a href=\"https:\/\/www.everywomanover29.com\/blog\/magnolia-officinalis-phellodendron-amurense-relora-cortisol-stress-anxiety\/\" target=\"_blank\" rel=\"noopener\">Magnolia officinalis and Phellodendron amurense (Relora\u00ae) lowers cortisol and reduces stress and anxiety<\/a><\/li>\n<li>Forest bathing &#8211; <a href=\"https:\/\/www.everywomanover29.com\/blog\/anxiety-stress-and-high-cortisol-forest-bathing-to-the-rescue\/\" target=\"_blank\" rel=\"noopener\">Anxiety, stress and high cortisol: forest bathing to the rescue<\/a><\/li>\n<li>Reducing Wi-Fi exposure &#8211; <a href=\"https:\/\/www.everywomanover29.com\/blog\/wi-fi-threat-to-human-health-anxiety-sibo-oxalate-issues-high-cortisol\/\" target=\"_blank\" rel=\"noopener\">Wi-Fi is an important threat to human health and may contribute to unresolved anxiety, SIBO, oxalate issues and high cortisol<\/a><\/li>\n<li>Tapping &#8211; <a href=\"https:\/\/www.everywomanover29.com\/blog\/tapping-or-eft-for-reducing-anxiety-depression-pain-and-cravings-plus-physiological-changes-in-cortisol-heart-rate-blood-pressure-and-siga\/\" target=\"_blank\" rel=\"noopener\">Tapping (or EFT) for reducing anxiety, depression, pain and cravings, plus physiological changes in cortisol, heart rate, blood pressure and SigA<\/a><\/li>\n<li>Essential oils &#8211; <a href=\"https:\/\/www.everywomanover29.com\/blog\/orange-essential-oil-ptsd-fear-stress-anxiety\/\" target=\"_blank\" rel=\"noopener\">Orange essential oil to alleviate PTSD, fear, stress and anxiety<\/a><\/li>\n<\/ul>\n<h2>Resources if you are new to using GABA and other amino acids as supplements<\/h2>\n<p>If you are new to using any of the amino acids as supplements, here is the <a href=\"https:\/\/www.everywomanover29.com\/blog\/amino-acids-mood-questionnaire-from-the-antianxiety-food-solution\/\" target=\"_blank\" rel=\"noopener\">Amino Acids Mood Questionnaire from The Antianxiety Food Solution<\/a> (you can see all the symptoms of neurotransmitter imbalances, including low GABA).<\/p>\n<p>If you suspect low levels of any of the neurotransmitters and do not yet have my book, <a href=\"https:\/\/www.everywomanover29.com\/blog\/the-antianxiety-food-solution-by-trudy-scott\/\" target=\"_blank\" rel=\"noopener\">The Antianxiety Food Solution \u2013 How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings<\/a>, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the practitioner\/health team you or your loved one is working with.<\/p>\n<p>There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, gluten, blood sugar control, sugar cravings, self-medicating with alcohol and more.<\/p>\n<p>The book doesn\u2019t include product names (per the publisher\u2019s request) so this blog, <a href=\"https:\/\/www.everywomanover29.com\/blog\/amino-acids-pyroluria-supplements\/\" target=\"_blank\" rel=\"noopener\">The Antianxiety Food Solution Amino Acid and Pyroluria Supplements<\/a>, lists the amino acids that I use with my individual clients and those in my group programs. You can find them all in my online store.<\/p>\n<p>You can also find Biotics Research De-Stress in my online store (see link above for how to set up an account and purchase).<\/p>\n<p>If, after reading this blog and my book, you don\u2019t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the <a href=\"https:\/\/www.anxietynutritioninstitute.com\/gabaquickstart\/\" target=\"_blank\" rel=\"noopener\">GABA QuickStart Program<\/a> (if you have low GABA symptoms). This is a paid online\/virtual group program where you get my guidance and community support.<\/p>\n<p>If you are a practitioner, join us in <a href=\"https:\/\/www.anxietynutritioninstitute.com\/balancingneurotransmitters\/\" target=\"_blank\" rel=\"noopener\">The Balancing Neurotransmitters: the Fundamentals<\/a> program. This is also a paid online\/virtual program with an opportunity to interact with me and other practitioners who are also using the amino acids.<\/p>\n<p>Have you used Lactium\u00ae for improving your sleep, reducing anxiety and\/or lowering your high cortisol?<\/p>\n<p>Have you also used any of the above approaches to lower cortisol or reduce anxiety too?<\/p>\n<p>How quickly did each one help?<\/p>\n<p>If you\u2019re a practitioner do you use Lactium\u00ae with success?<\/p>\n<p>If you have questions please share them here too.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lactium\u00ae is my second choice for lowering high cortisol and reducing the type of anxiety that we see when cortisol is high i.e. anxiety that feels like an adrenaline-type surge.\u00a0 It is especially helpful when cortisol is high as you wake up. This can be confirmed by a 4 collection saliva test. The reason why [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":10683,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[1172,1298],"tags":[2649,2647,46,2560,304,2396,1130,2648,152,1204,910,2650,908,128],"class_list":["post-10682","post","type-post","status-publish","format-standard","has-post-thumbnail","category-anxiety","category-insomnia","tag-adrenaline-type-surge","tag-alpha-s1-casein-hydrolysate","tag-anxiety","tag-balancing-neurotransmitters-the-fundamentals-program-for-practitioners","tag-cortisol","tag-gaba-quickstart-program","tag-high-cortisol","tag-hydrolyzed-casein","tag-insomnia","tag-lactium","tag-phosphorylated-serine","tag-saliva-test","tag-seriphos","tag-sleep","entry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Lactium\u00ae (alpha-s1 casein hydrolysate\/hydrolyzed casein) for lowering high cortisol, reducing anxiety and improving sleep - everywomanover29 blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.everywomanover29.com\/blog\/lactium-alpha-s1-casein-hydrolysate-hydrolyzed-casein-for-lowering-high-cortisol-reducing-anxiety-and-improving-sleep\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lactium\u00ae (alpha-s1 casein hydrolysate\/hydrolyzed casein) for lowering high cortisol, reducing anxiety and improving sleep - everywomanover29 blog\" \/>\n<meta property=\"og:description\" content=\"Lactium\u00ae is my second choice for lowering high cortisol and reducing the type of anxiety that we see when cortisol is high i.e. anxiety that feels like an adrenaline-type surge.\u00a0 It is especially helpful when cortisol is high as you wake up. 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The reason why [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.everywomanover29.com\/blog\/lactium-alpha-s1-casein-hydrolysate-hydrolyzed-casein-for-lowering-high-cortisol-reducing-anxiety-and-improving-sleep\/\" \/>\n<meta property=\"og:site_name\" content=\"everywomanover29 blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/TrudyScottAntianxietyFoodSolution\" \/>\n<meta property=\"article:published_time\" content=\"2022-10-14T21:00:14+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.everywomanover29.com\/blog\/wp-content\/uploads\/2022\/10\/lactium-anxiety.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"940\" \/>\n\t<meta property=\"og:image:height\" content=\"492\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Trudy Scott\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@foodmoodexpert\" \/>\n<meta name=\"twitter:site\" content=\"@foodmoodexpert\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Trudy Scott\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/lactium-alpha-s1-casein-hydrolysate-hydrolyzed-casein-for-lowering-high-cortisol-reducing-anxiety-and-improving-sleep\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/lactium-alpha-s1-casein-hydrolysate-hydrolyzed-casein-for-lowering-high-cortisol-reducing-anxiety-and-improving-sleep\\\/\"},\"author\":{\"name\":\"Trudy Scott\",\"@id\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/#\\\/schema\\\/person\\\/0992b9ecc4de889bd46f1226dc787b5b\"},\"headline\":\"Lactium\u00ae (alpha-s1 casein hydrolysate\\\/hydrolyzed casein) for lowering high cortisol, reducing anxiety and improving sleep\",\"datePublished\":\"2022-10-14T21:00:14+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/lactium-alpha-s1-casein-hydrolysate-hydrolyzed-casein-for-lowering-high-cortisol-reducing-anxiety-and-improving-sleep\\\/\"},\"wordCount\":1264,\"commentCount\":29,\"image\":{\"@id\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/lactium-alpha-s1-casein-hydrolysate-hydrolyzed-casein-for-lowering-high-cortisol-reducing-anxiety-and-improving-sleep\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/10\\\/lactium-anxiety.jpg\",\"keywords\":[\"adrenaline-type surge\",\"alpha-s1 casein hydrolysate\",\"anxiety\",\"Balancing Neurotransmitters: the Fundamentals program for practitioners\",\"cortisol\",\"GABA Quickstart program\",\"high cortisol\",\"hydrolyzed casein\",\"insomnia\",\"lactium\",\"phosphorylated serine\",\"saliva test\",\"seriphos\",\"sleep\"],\"articleSection\":[\"Anxiety\",\"Insomnia\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/lactium-alpha-s1-casein-hydrolysate-hydrolyzed-casein-for-lowering-high-cortisol-reducing-anxiety-and-improving-sleep\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/lactium-alpha-s1-casein-hydrolysate-hydrolyzed-casein-for-lowering-high-cortisol-reducing-anxiety-and-improving-sleep\\\/\",\"url\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/lactium-alpha-s1-casein-hydrolysate-hydrolyzed-casein-for-lowering-high-cortisol-reducing-anxiety-and-improving-sleep\\\/\",\"name\":\"Lactium\u00ae (alpha-s1 casein hydrolysate\\\/hydrolyzed casein) for lowering high cortisol, reducing anxiety and improving sleep - 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Trudy is the author of The Antianxiety Food Solution: How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood and End Cravings and host of The Anxiety Summit now in its 6th season and called a \u201cbouquet of hope.\u201d Trudy is passionate about sharing the powerful food mood connection because she experienced the results first-hand, finding complete resolution of her anxiety and panic attacks.\",\"url\":\"https:\\\/\\\/www.everywomanover29.com\\\/blog\\\/author\\\/everywomanover29\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Lactium\u00ae (alpha-s1 casein hydrolysate\/hydrolyzed casein) for lowering high cortisol, reducing anxiety and improving sleep - everywomanover29 blog","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.everywomanover29.com\/blog\/lactium-alpha-s1-casein-hydrolysate-hydrolyzed-casein-for-lowering-high-cortisol-reducing-anxiety-and-improving-sleep\/","og_locale":"en_US","og_type":"article","og_title":"Lactium\u00ae (alpha-s1 casein hydrolysate\/hydrolyzed casein) for lowering high cortisol, reducing anxiety and improving sleep - everywomanover29 blog","og_description":"Lactium\u00ae is my second choice for lowering high cortisol and reducing the type of anxiety that we see when cortisol is high i.e. anxiety that feels like an adrenaline-type surge.\u00a0 It is especially helpful when cortisol is high as you wake up. This can be confirmed by a 4 collection saliva test. 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